Kenneth McMartin

Kenneth McMartin

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Kenneth McMartin

Kenneth McMartin

Publications by authors named "Kenneth McMartin"

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Curcumin gum formulation for prevention of oral cavity head and neck squamous cell carcinoma.

Laryngoscope 2018 Nov 13. Epub 2018 Nov 13.

Department of Otolaryngology-Head and Neck Surgery, Louisiana State University- Health Sciences Center, Shreveport, Louisiana, U.S.A.

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http://doi.wiley.com/10.1002/lary.27542
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http://dx.doi.org/10.1002/lary.27542DOI Listing
November 2018

Human health assessment for long-term oral ingestion of diethylene glycol.

Regul Toxicol Pharmacol 2017 Jun 29;87 Suppl 2:S1-S20. Epub 2017 Apr 29.

Toxicology and Environmental Research and Consulting, The Dow Chemical Company, Midland, MI 48640 USA. Electronic address:

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http://dx.doi.org/10.1016/j.yrtph.2017.03.027DOI Listing
June 2017

In-vivo evidence of nephrotoxicity and altered hepatic function in rats following administration of diglycolic acid, a metabolite of diethylene glycol.

Clin Toxicol (Phila) 2017 Mar 11;55(3):196-205. Epub 2017 Jan 11.

a Department of Pharmacology, Toxicology and Neuroscience , Louisiana State University Health Sciences Center - Shreveport , Shreveport , LA , USA.

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http://dx.doi.org/10.1080/15563650.2016.1271128DOI Listing
March 2017

Diglycolic acid, the toxic metabolite of diethylene glycol, chelates calcium and produces renal mitochondrial dysfunction in vitro.

Clin Toxicol (Phila) 2016 Jul 22;54(6):501-11. Epub 2016 Mar 22.

b Department of Pharmacology, Toxicology, and Neuroscience , Louisiana State University Health Sciences Center , Shreveport , LA , USA ;

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http://dx.doi.org/10.3109/15563650.2016.1162312DOI Listing
July 2016

Antidotes for poisoning by alcohols that form toxic metabolites.

Br J Clin Pharmacol 2016 Mar 4;81(3):505-15. Epub 2016 Jan 4.

The Norwegian CBRNe Centre of Medicine, Department of Acute Medicine, Division of Medicine, Oslo University Hospital, NO-0424, Oslo, Norway.

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http://biochem.flas.kps.ku.ac.th/02738451/alcohol_toxic.pdf
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http://dx.doi.org/10.1111/bcp.12824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767193PMC
March 2016

Enhanced Systemic Bioavailability of Curcumin Through Transmucosal Administration of a Novel Microgranular Formulation.

Anticancer Res 2015 Dec;35(12):6411-8

Feist-Weiller Cancer Center, Louisiana State University Health Sciences Center, Shreveport, LA, U.S.A. Department of Otolaryngology-Head and Neck Surgery, Louisiana State University Health Sciences Center, Shreveport, LA, U.S.A.

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http://ar.iiarjournals.org/content/35/12/6411.full.pdf
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December 2015

Diethylene glycol-induced toxicities show marked threshold dose response in rats.

Toxicol Appl Pharmacol 2015 Feb 26;282(3):244-51. Epub 2014 Dec 26.

Department of Pharmacology, Toxicology, & Neuroscience, Louisiana State University Health Sciences Center, Shreveport, LA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2014.12.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237385PMC
February 2015

Quantitation of diethylene glycol and its metabolites by gas chromatography mass spectrometry or ion chromatography mass spectrometry in rat and human biological samples.

J Anal Toxicol 2014 May 25;38(4):184-93. Epub 2014 Mar 25.

1Toxicology and Environmental Research and Consulting, The Dow Chemical Company, Midland, MI, USA.

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https://academic.oup.com/jat/article/38/4/184/2798005
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http://dx.doi.org/10.1093/jat/bku018DOI Listing
May 2014

Aluminum citrate blocks toxicity of calcium oxalate crystals by preventing binding with cell membrane phospholipids.

Am J Nephrol 2013 4;37(1):41-9. Epub 2013 Jan 4.

Department of Pharmacology, Toxicology and Neuroscience, Louisiana State University Health Sciences Center, Shreveport, LA 71130-3932, USA.

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http://dx.doi.org/10.1159/000345985DOI Listing
August 2013

Diglycolic acid inhibits succinate dehydrogenase activity in human proximal tubule cells leading to mitochondrial dysfunction and cell death.

Toxicol Lett 2013 Aug 1;221(3):176-84. Epub 2013 Jul 1.

Department of Pharmacology, Toxicology, and Neuroscience, Louisiana State University Health Sciences Center, Shreveport, LA, USA.

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http://dx.doi.org/10.1016/j.toxlet.2013.06.231DOI Listing
August 2013

Oral Reference Dose for ethylene glycol based on oxalate crystal-induced renal tubule degeneration as the critical effect.

Regul Toxicol Pharmacol 2013 Mar 22;65(2):229-41. Epub 2012 Dec 22.

Snellings Toxicology Consulting, LLC, 23 Trails End Lane, Ridgefield, CT 06877, USA.

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http://dx.doi.org/10.1016/j.yrtph.2012.12.005DOI Listing
March 2013

Aluminum citrate prevents renal injury from calcium oxalate crystal deposition.

J Am Soc Nephrol 2012 Dec 8;23(12):2024-33. Epub 2012 Nov 8.

Department of Pharmacology, Toxicology, and Neuroscience, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130-3932, USA.

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http://dx.doi.org/10.1681/ASN.2012040357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507364PMC
December 2012

Kinetics of fomepizole in pregnant rats.

Clin Toxicol (Phila) 2012 Sep 14;50(8):743-8. Epub 2012 Aug 14.

Department of Pharmacology, Toxicology and Neuroscience, Lousiana State University Health Sciences Center, Shreveport, LA 71130, USA.

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http://dx.doi.org/10.3109/15563650.2012.716518DOI Listing
September 2012

Kinetics and metabolism of fomepizole in healthy humans.

Clin Toxicol (Phila) 2012 Jun 4;50(5):375-83. Epub 2012 May 4.

Department of Pharmacology, Toxicology and Neuroscience, Lousiana State University Health Sciences Center - Shreveport, Shreveport , LA 71130-3932, USA.

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http://dx.doi.org/10.3109/15563650.2012.683197DOI Listing
June 2012

Diglycolic acid is the nephrotoxic metabolite in diethylene glycol poisoning inducing necrosis in human proximal tubule cells in vitro.

Toxicol Sci 2011 Nov 18;124(1):35-44. Epub 2011 Aug 18.

Department of Pharmacology, Toxicology, and Neuroscience, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130-3932, USA.

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http://dx.doi.org/10.1093/toxsci/kfr204DOI Listing
November 2011

Role of tissue metabolite accumulation in the renal toxicity of diethylene glycol.

Toxicol Sci 2011 Oct 29;123(2):374-83. Epub 2011 Jul 29.

Department of Pharmacology, Toxicology and Neuroscience, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130-3932, USA.

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http://dx.doi.org/10.1093/toxsci/kfr197DOI Listing
October 2011

Methods to evaluate the effect of ethanol on the folate analogue: fluorescein methotrexate uptake in human proximal tubular cells.

Adv Pharmacol Sci 2009 29;2009:291349. Epub 2009 Sep 29.

Department of Pharmacology, LSU Health Sciences Center, Shreveport, LA 71118, USA.

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http://dx.doi.org/10.1155/2009/291349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990105PMC
July 2011

Inhibition of metabolism of diethylene glycol prevents target organ toxicity in rats.

Toxicol Sci 2010 Sep 7;117(1):25-35. Epub 2010 Jun 7.

Department of Pharmacology, Toxicology and Neuroscience, Louisiana State University Health Sciences Center-Shreveport, Shreveport, Louisiana 71130-3932, USA.

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http://dx.doi.org/10.1093/toxsci/kfq167DOI Listing
September 2010

Involvement of urinary proteins in the rat strain difference in sensitivity to ethylene glycol-induced renal toxicity.

Am J Physiol Renal Physiol 2010 Sep 9;299(3):F605-15. Epub 2010 Jun 9.

Department of Pharmacology, Toxicology, and Neuroscience, Louisiana State University Health Sciences Center, Shreveport, USA.

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http://dx.doi.org/10.1152/ajprenal.00419.2009DOI Listing
September 2010

Renal toxicity of ethylene glycol results from internalization of calcium oxalate crystals by proximal tubule cells.

Toxicol Lett 2010 Feb 18;192(3):365-72. Epub 2009 Nov 18.

Department of Pharmacology, Toxicology & Neuroscience, Louisiana State University Health Sciences Center, Shreveport, LA 71130-3932, USA.

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http://dx.doi.org/10.1016/j.toxlet.2009.11.013DOI Listing
February 2010

Are calcium oxalate crystals involved in the mechanism of acute renal failure in ethylene glycol poisoning?

Authors:
Kenneth McMartin

Clin Toxicol (Phila) 2009 Nov;47(9):859-69

Department of Pharmacology, Toxicology & Neuroscience, Louisiana State University Health Sciences Center, Shreveport, LA, USA.

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http://dx.doi.org/10.3109/15563650903344793DOI Listing
November 2009

Strain differences in urinary factors that promote calcium oxalate crystal formation in the kidneys of ethylene glycol-treated rats.

Am J Physiol Renal Physiol 2009 May 25;296(5):F1080-7. Epub 2009 Feb 25.

Department of Pharmacology, Toxicology and Neuroscience, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.

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http://dx.doi.org/10.1152/ajprenal.90727.2008DOI Listing
May 2009

Relationship between serum glycolate and falsely elevated lactate in severe ethylene glycol poisoning.

J Anal Toxicol 2009 Apr;33(3):174-6

New York City Poison Control Center, Department of Health and Mental Hygiene, New York, New York, USA.

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http://dx.doi.org/10.1093/jat/33.3.174DOI Listing
April 2009

Inhibition of NADPH oxidase activity promotes differentiation of B16 melanoma cells.

Oncol Rep 2008 May;19(5):1225-30

Department of Pharmacology, Toxicology and Neuroscience, LSU Health Sciences Center-Shreveport, Shreveport, LA 71130, USA.

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May 2008

Oral administration of fomepizole produces similar blood levels as identical intravenous dose.

Clin Toxicol (Phila) 2008 Mar;46(3):181-6

Department of Emergency Medicine, SUNY Upstate Medical University, Syracuse, New York 13210, USA.

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http://dx.doi.org/10.1080/15563650701373796DOI Listing
March 2008

Calcium oxalate, and not other metabolites, is responsible for the renal toxicity of ethylene glycol.

Toxicol Lett 2007 Aug 20;173(1):8-16. Epub 2007 Jun 20.

Department of Pharmacology, Toxicology & Neuroscience, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130-3932, United States.

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http://dx.doi.org/10.1016/j.toxlet.2007.06.010DOI Listing
August 2007

Extremely slow formate elimination in severe methanol poisoning: a fatal case report.

Clin Toxicol (Phila) 2007 Jun-Aug;45(5):516-21

Department of Acute Medicine, Ullevaal University Hospital, Oslo, Norway.

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http://www.tandfonline.com/doi/full/10.1080/1556365070135415
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http://dx.doi.org/10.1080/15563650701354150DOI Listing
July 2007

Acute ethanol exposure inhibits renal folate transport, but repeated exposure upregulates folate transport proteins in rats and human cells.

J Nutr 2007 May;137(5):1260-5

Department of Pharmacology, Toxicology, and Neuroscience, Louisiana State University Health Sciences Center, Shreveport, LA 71130-3932, USA.

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http://dx.doi.org/10.1093/jn/137.5.1260DOI Listing
May 2007

Aluminum citrate inhibits cytotoxicity and aggregation of oxalate crystals.

Toxicology 2007 Feb 15;230(2-3):117-25. Epub 2006 Nov 15.

Department of Pharmacology, Toxicology & Neuroscience, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130-3932, USA.

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http://dx.doi.org/10.1016/j.tox.2006.11.046DOI Listing
February 2007

Calcium oxalate monohydrate, a metabolite of ethylene glycol, is toxic for rat renal mitochondrial function.

Toxicol Sci 2005 Mar 15;84(1):195-200. Epub 2004 Dec 15.

Department of Pharmacology and Therapeutics, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, Louisiana 71130-3932, USA.

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http://dx.doi.org/10.1093/toxsci/kfi062DOI Listing
March 2005

The cytotoxicity of oxalate, metabolite of ethylene glycol, is due to calcium oxalate monohydrate formation.

Toxicology 2005 Mar;208(3):347-55

Department of Pharmacology and Therapeutics, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130-3932, USA.

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http://dx.doi.org/10.1016/j.tox.2004.11.029DOI Listing
March 2005

Subchronic toxicity of ethylene glycol in Wistar and F-344 rats related to metabolism and clearance of metabolites.

Toxicol Sci 2004 Oct 30;81(2):502-11. Epub 2004 Jun 30.

ToxWorks, 1153 Roadstown Road, Bridgeton, New Jersey 08302, USA.

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http://dx.doi.org/10.1093/toxsci/kfh206DOI Listing
October 2004

Formate kinetics in methanol poisoning.

J Toxicol Clin Toxicol 2002 ;40(2):137-43

Emergency Medicine and Toxicology, Carolinas Medical Center, Charlotte, North Carolina 28232-2861, USA.

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July 2002