Kenneth Marek

Kenneth Marek

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Kenneth Marek

Kenneth Marek

Publications by authors named "Kenneth Marek"

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Concordance for Parkinson's disease in twins: A 20-year update.

Ann Neurol 2019 Apr 11;85(4):600-605. Epub 2019 Mar 11.

Department of Neurology; University of California-San Francisco, San Francisco Veterans Affairs Health Care System, University of California-San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1002/ana.25441DOI Listing
April 2019

Plasma α-synuclein and cognitive impairment in the Parkinson's Associated Risk Syndrome: A pilot study.

Neurobiol Dis 2018 08 27;116:53-59. Epub 2018 Apr 27.

Department of Pathology, Peking University Health Science Centre and Third Hospital, Beijing 100191, China; Department of Pathology, University of Washington School of Medicine, Seattle, WA 98104-2499, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2018.04.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294306PMC
August 2018

Observations on a 2-Step Approach to Screening for Parkinson Disease-Reply.

JAMA Neurol 2017 12;74(12):1506-1507

Institute for Neurodegenerative Disorders, New Haven, Connecticut.

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http://dx.doi.org/10.1001/jamaneurol.2017.3208DOI Listing
December 2017

Longitudinal CSF biomarkers in patients with early Parkinson disease and healthy controls.

Neurology 2017 Nov 13;89(19):1959-1969. Epub 2017 Oct 13.

From the Department of Neurology (B.M.), University Medical Center, Göttingen; Paracelsus-Elena-Klinik (B.M.), Kassel, Germany; Department of Biostatistics (C.J.C.-G., C.S.C.), College of Public Health, University of Iowa, Iowa City; BioLegend Inc. (P.T.), San Diego, CA; Department of Pathology & Laboratory Medicine (L.M.S., J.Q.T.), Center for Neurodegenerative Disease Research, Institute on Aging (L.M.S. , J.Q.T.), and Morris K. Udall Center of Excellence for Parkinson's Disease Research (J.Q.T.), Perelman School of Medicine, University of Pennsylvania, Philadelphia; Molecular Genetics Section (A.S.), Laboratory of Neurogenetics, National Institute on Aging, NIH, Bethesda, MD; The Michael J. Fox Foundation for Parkinson's Research (M.F.), New York, NY; Institute for Neurodegenerative Disorders (K.M.), New Haven, CT; and Department of Neurosciences (D.G.), University of California, San Diego.

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http://dx.doi.org/10.1212/WNL.0000000000004609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679418PMC
November 2017

Clinical utility of DaTscan™ imaging in the evaluation of patients with parkinsonism: a US perspective.

Expert Rev Neurother 2017 03 23;17(3):219-225. Epub 2016 Nov 23.

g Institute for Neurodegenerative Disorders , New Haven , CT , USA.

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http://dx.doi.org/10.1080/14737175.2017.1256205DOI Listing
March 2017

Predictors of time to initiation of symptomatic therapy in early Parkinson's disease.

Ann Clin Transl Neurol 2016 Jul 17;3(7):482-94. Epub 2016 May 17.

Institute for Neurodegenerative Disorders (IND) Molecular NeuroImaging LLC (MNI) New Haven Connecticut.

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http://dx.doi.org/10.1002/acn3.317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931714PMC
July 2016

Change in PDE10 across early Huntington disease assessed by [18F]MNI-659 and PET imaging.

Neurology 2016 Feb 22;86(8):748-54. Epub 2016 Jan 22.

From the Institute for Neurodegenerative Disorders and Molecular NeuroImaging, New Haven, CT.

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http://dx.doi.org/10.1212/WNL.0000000000002391DOI Listing
February 2016

Testosterone level and the effect of levodopa and agonists in early Parkinson disease: results from the INSPECT cohort.

J Clin Mov Disord 2014 26;1. Epub 2014 Nov 26.

Departments of Neurology, Neurosurgery and Psychiatry, McKnight Brain Institute, University of Florida, 100 S Newell Dr Rm-L3-101, Gainesville, 32611 FL USA.

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http://dx.doi.org/10.1186/2054-7072-1-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711001PMC
January 2016

Clinical correlates of raphe serotonergic dysfunction in early Parkinson's disease.

Brain 2015 Oct 23;138(Pt 10):2964-73. Epub 2015 Jul 23.

1 Division of Brain Sciences, Imperial College London, South Kensington Campus, London, SW7 2AZ, UK 3 Department of Nuclear Medicine and PET Centre, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus, Denmark

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http://dx.doi.org/10.1093/brain/awv215DOI Listing
October 2015

Novel recruitment strategy to enrich for LRRK2 mutation carriers.

Mol Genet Genomic Med 2015 Sep 6;3(5):404-12. Epub 2015 May 6.

Institute for Neurodegenerative Disorders New Haven, Connecticut, 06510.

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http://dx.doi.org/10.1002/mgg3.151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585448PMC
September 2015

Author Response.

Neurology 2015 Jun;84(22):2292

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June 2015

Imaging prodromal Parkinson disease: the Parkinson Associated Risk Syndrome Study.

Neurology 2014 Nov 8;83(19):1739-46. Epub 2014 Oct 8.

From the Institute for Neurodegenerative Disorders (D.J., J.S., K.M.), New Haven, CT; Parkinson's Disease and Movement Disorders Center (M.S.), Department of Neurology, University of Pennsylvania, Philadelphia; Department of Biostatistics and Computational Biology (S.E., D.O.), University of Rochester, NY; and Avid Radiopharmaceuticals (A.S.), Philadelphia, PA.

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http://dx.doi.org/10.1212/WNL.0000000000000960DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239830PMC
November 2014

A practical approach to remote longitudinal follow-up of Parkinson's disease: the FOUND study.

Mov Disord 2014 May 11;29(6):743-9. Epub 2014 Feb 11.

Clinical Research, The Parkinson's Institute, Sunnyvale, California, USA; Department of Health Research and Policy, Stanford University, Palo Alto, California, USA.

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http://dx.doi.org/10.1002/mds.25814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656448PMC
May 2014

Longitudinal follow-up of SWEDD subjects in the PRECEPT Study.

Neurology 2014 May 23;82(20):1791-7. Epub 2014 Apr 23.

From the Institute for Neurodegenerative Disorders (K.M., J.S., D.J.), University of Rochester (S.E., D.O.), Rochester, NY; Georgetown University (I.S.), Washington, DC; University of Toronto (A.E.L.); and Western University (C.H.), London, Ontario, Canada.

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http://dx.doi.org/10.1212/WNL.0000000000000424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035714PMC
May 2014

Reply: Unusual DAT scan results.

Mov Disord 2013 Jun 4;28(6):847. Epub 2013 Apr 4.

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http://dx.doi.org/10.1002/mds.25447DOI Listing
June 2013

Traditional neuropsychological correlates and reliability of the automated neuropsychological assessment metrics-4 battery for Parkinson's disease.

Parkinsonism Relat Disord 2012 Aug 18;18(7):864-70. Epub 2012 May 18.

Yale University School of Medicine, New Haven, Connecticut 06519, USA.

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http://dx.doi.org/10.1016/j.parkreldis.2012.04.021DOI Listing
August 2012

Impaired olfaction and other prodromal features in the Parkinson At-Risk Syndrome Study.

Mov Disord 2012 Mar 11;27(3):406-12. Epub 2012 Jan 11.

Parkinson's Disease and Movement Disorders Center, Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19107, USA.

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http://dx.doi.org/10.1002/mds.24892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342466PMC
March 2012

Molecular PET imaging in multicenter Alzheimer's therapeutic trials: current trends and implementation strategies.

Expert Rev Neurother 2011 Dec;11(12):1783-93

Institute for Neurodegenerative Disorders, Duke University, New Haven, NC, USA.

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http://dx.doi.org/10.1586/ern.11.168DOI Listing
December 2011

Serum urate and probability of dopaminergic deficit in early "Parkinson's disease".

Mov Disord 2011 Aug 29;26(10):1864-8. Epub 2011 Apr 29.

Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/mds.23741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150627PMC
August 2011

The role of the core imaging laboratory in multicenter trials.

Semin Nucl Med 2010 Sep;40(5):338-46

Molecular Neuroimaging, LLC, Institute for Neurodegenerative Disorders, and Yale University School of Medicine, New Haven, CT, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00012998100001
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http://dx.doi.org/10.1053/j.semnuclmed.2010.03.002DOI Listing
September 2010

Rationale for delayed-start study of pramipexole in Parkinson's disease: the PROUD study.

Mov Disord 2010 Aug;25(11):1627-32

Department of Clinical Neurosciences, Institute of Neurology, University College London, London, United Kingdom.

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http://dx.doi.org/10.1002/mds.23143DOI Listing
August 2010

Supplement neuroimaging movement disorders.

Mov Disord 2009 ;24 Suppl 2:S655

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http://dx.doi.org/10.1002/mds.22770DOI Listing
January 2010

Can we image premotor Parkinson disease?

Neurology 2009 Feb;72(7 Suppl):S21-6

Institute for Neurodegenerative Disorders, New Haven, CT, USA.

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http://dx.doi.org/10.1212/WNL.0b013e318198df97DOI Listing
February 2009

Biomarkers for Parkinson's [corrected] disease: tools to assess Parkinson's disease onset and progression.

Ann Neurol 2008 Dec;64 Suppl 2:S111-21

Institute for Neurodegenerative Disorders, New Haven, CT, USA.

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http://dx.doi.org/10.1002/ana.21602DOI Listing
December 2008

Striatal dopamine transporters correlate with simple reaction time in elderly subjects.

Neurobiol Aging 2008 Aug 23;29(8):1237-46. Epub 2007 Mar 23.

Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, United States.

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http://dx.doi.org/10.1016/j.neurobiolaging.2007.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523216PMC
August 2008

The specificity and sensitivity of transcranial ultrasound in the differential diagnosis of Parkinson's disease: a prospective blinded study.

Lancet Neurol 2008 May 3;7(5):417-24. Epub 2008 Apr 3.

Center of Neurology, Department of Neurodegeneration and Hertie Institute of Clinical Brain Research, University of Tübingen, Germany.

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http://dx.doi.org/10.1016/S1474-4422(08)70067-XDOI Listing
May 2008

Risk factors for Parkinson's disease and impaired olfaction in relatives of patients with Parkinson's disease.

Mov Disord 2007 Nov;22(15):2249-55

Parkinson's Disease and Movement Disorders Center, Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1002/mds.21707DOI Listing
November 2007

Optimized, automated striatal uptake analysis applied to SPECT brain scans of Parkinson's disease patients.

J Nucl Med 2007 Jun 15;48(6):857-64. Epub 2007 May 15.

Institute for Neurodegenerative Disorders, and Molecular Neuroimaging, LLC, New Haven, Connecticut 06510, USA.

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http://dx.doi.org/10.2967/jnumed.106.037432DOI Listing
June 2007

Levodopa and the progression of Parkinson's disease.

N Engl J Med 2004 Dec;351(24):2498-508

Columbia University, New York, USA.

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http://dx.doi.org/10.1056/NEJMoa033447DOI Listing
December 2004

Looking backward to move forward: early detection of neurodegenerative disorders.

Science 2003 Oct;302(5646):830-4

Department of Neurology and Alzheimer Disease Research Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://www.sciencemag.org/cgi/doi/10.1126/science.1090349
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http://dx.doi.org/10.1126/science.1090349DOI Listing
October 2003

Imaging the dopamine system to assess disease-modifying drugs: studies comparing dopamine agonists and levodopa.

Neurology 2003 Sep;61(6 Suppl 3):S43-8

Institute for Neurodegenerative Disorders, New Haven, Connecticut 06510, USA.

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http://dx.doi.org/10.1212/wnl.61.6_suppl_3.s43DOI Listing
September 2003

Dopamine agonists and Parkinson's disease progression: what can we learn from neuroimaging studies.

Ann Neurol 2003 ;53 Suppl 3:S160-6; discussion S166-9

Institute for Neurodegenerative Disorders, New Haven, CT 06510, USA.

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http://dx.doi.org/10.1002/ana.10486DOI Listing
April 2003

Single-photon emission tomography and dopamine transporter imaging in Parkinson's disease.

Adv Neurol 2003 ;91:183-91

Department of Neurology, Institute for Neurogenerative Disorders, New Haven, Connecticut, USA.

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January 2003

The natural history of the syndrome of primary progressive freezing gait.

Arch Neurol 2002 Nov;59(11):1778-83

Parkinson's Disease and Movement Disorder Center of Albany Medical Center, 215 Washington Ave Extension, Albany, NY 12203, USA.

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http://dx.doi.org/10.1001/archneur.59.11.1778DOI Listing
November 2002