Kenneth M Kaufman

Kenneth M Kaufman

UNVERIFIED PROFILE

Are you Kenneth M Kaufman?   Register this Author

Register author
Kenneth M Kaufman

Kenneth M Kaufman

Publications by authors named "Kenneth M Kaufman"

Are you Kenneth M Kaufman?   Register this Author

94Publications

5673Reads

12Profile Views

A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus.

Hum Mol Genet 2018 07;27(13):2392-2404

Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddy140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005081PMC
July 2018

Profound loss of esophageal tissue differentiation in patients with eosinophilic esophagitis.

J Allergy Clin Immunol 2017 Sep 17;140(3):738-749.e3. Epub 2017 Jan 17.

Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaci.2016.11.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513800PMC
September 2017

Transancestral mapping and genetic load in systemic lupus erythematosus.

Authors:
Carl D Langefeld Hannah C Ainsworth Deborah S Cunninghame Graham Jennifer A Kelly Mary E Comeau Miranda C Marion Timothy D Howard Paula S Ramos Jennifer A Croker David L Morris Johanna K Sandling Jonas Carlsson Almlöf Eduardo M Acevedo-Vásquez Graciela S Alarcón Alejandra M Babini Vicente Baca Anders A Bengtsson Guillermo A Berbotto Marc Bijl Elizabeth E Brown Hermine I Brunner Mario H Cardiel Luis Catoggio Ricard Cervera Jorge M Cucho-Venegas Solbritt Rantapää Dahlqvist Sandra D'Alfonso Berta Martins Da Silva Iñigo de la Rúa Figueroa Andrea Doria Jeffrey C Edberg Emőke Endreffy Jorge A Esquivel-Valerio Paul R Fortin Barry I Freedman Johan Frostegård Mercedes A García Ignacio García de la Torre Gary S Gilkeson Dafna D Gladman Iva Gunnarsson Joel M Guthridge Jennifer L Huggins Judith A James Cees G M Kallenberg Diane L Kamen David R Karp Kenneth M Kaufman Leah C Kottyan László Kovács Helle Laustrup Bernard R Lauwerys Quan-Zhen Li Marco A Maradiaga-Ceceña Javier Martín Joseph M McCune David R McWilliams Joan T Merrill Pedro Miranda José F Moctezuma Swapan K Nath Timothy B Niewold Lorena Orozco Norberto Ortego-Centeno Michelle Petri Christian A Pineau Bernardo A Pons-Estel Janet Pope Prithvi Raj Rosalind Ramsey-Goldman John D Reveille Laurie P Russell José M Sabio Carlos A Aguilar-Salinas Hugo R Scherbarth Raffaella Scorza Michael F Seldin Christopher Sjöwall Elisabet Svenungsson Susan D Thompson Sergio M A Toloza Lennart Truedsson Teresa Tusié-Luna Carlos Vasconcelos Luis M Vilá Daniel J Wallace Michael H Weisman Joan E Wither Tushar Bhangale Jorge R Oksenberg John D Rioux Peter K Gregersen Ann-Christine Syvänen Lars Rönnblom Lindsey A Criswell Chaim O Jacob Kathy L Sivils Betty P Tsao Laura E Schanberg Timothy W Behrens Earl D Silverman Marta E Alarcón-Riquelme Robert P Kimberly John B Harley Edward K Wakeland Robert R Graham Patrick M Gaffney Timothy J Vyse

Nat Commun 2017 07 17;8:16021. Epub 2017 Jul 17.

Divisions of Genetics and Molecular Medicine and Immunology, Infection and Inflammatory Diseases, King's College London, Guy's Hospital, London SE1 9RT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms16021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520018PMC
July 2017

Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons.

PLoS Genet 2017 Jun 22;13(6):e1006820. Epub 2017 Jun 22.

Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1006820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501660PMC
June 2017

X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome.

Arthritis Rheumatol 2016 05;68(5):1290-1300

College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/art.39560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019501PMC
May 2016

Focused transcription from the human CR2/CD21 core promoter is regulated by synergistic activity of TATA and Initiator elements in mature B cells.

Cell Mol Immunol 2016 Jan 2;13(1):119-31. Epub 2015 Feb 2.

School of Pathology and Laboratory Medicine, Centre for Genetic Origins of Health and Disease, The University of Western Australia, Crawley, WA, Australia.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/cmi2014138
Publisher Site
http://dx.doi.org/10.1038/cmi.2014.138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711682PMC
January 2016

The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.

Hum Mol Genet 2015 Jan 8;24(2):582-96. Epub 2014 Sep 8.

Division of Rheumatology, Center for Autoimmune Genomics and Etiology and US Department of Veterans Affairs Medical Center, Cincinnati, OH, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddu455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275071PMC
January 2015

Challenges and cautions with small and retrospective postoperative pain genome-wide association studies with TAOK3.

Pain 2014 Nov 17;155(11):2434-5. Epub 2014 Aug 17.

Department of Pediatrics and Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

View Article

Download full-text PDF

Source
http://Insights.ovid.com/crossref?an=00006396-201411000-0002
Publisher Site
http://dx.doi.org/10.1016/j.pain.2014.08.008DOI Listing
November 2014

Whole exome sequencing for familial bicuspid aortic valve identifies putative variants.

Circ Cardiovasc Genet 2014 Oct 1;7(5):677-83. Epub 2014 Aug 1.

From the Department of Pediatrics, Cincinnati Children's Hospital Medical Center, OH (L.J.M., V.P., K.M.K., L.C.K., M.K., P.D., M.T.W.); Department of Pediatrics, University of Cincinnati School of Medicine, Cincinnati OH (L.J.M., K.M.K., M.K., M.T.W.); Department of Pediatrics, Nationwide Children's Hospital, The Ohio State University, Columbus (L.C.); Herma Heart Center, Children's Hospital of Wisconsin, Milwaukee (D.W.B.); and Department of Pediatrics, Medical College of Wisconsin, Milwaukee (D.W.B.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCGENETICS.114.000526DOI Listing
October 2014

The struggle to find reliable results in exome sequencing data: filtering out Mendelian errors.

Front Genet 2014 12;5:16. Epub 2014 Feb 12.

Division of Rheumatology, Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati OH, USA ; Department of Veterans Affairs, Veterans Affairs Medical Center - Cincinnati, Cincinnati OH, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fgene.2014.00016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921572PMC
February 2014

Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome.

Nat Genet 2013 Nov 6;45(11):1284-92. Epub 2013 Oct 6.

1] Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA. [2] Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.2792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867192PMC
November 2013

Mapping susceptibility gene in systemic lupus erythematosus.

Methods Mol Biol 2012 ;900:11-24

Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/978-1-60761-720-4_2
Publisher Site
http://dx.doi.org/10.1007/978-1-60761-720-4_2DOI Listing
January 2013

IRF5 gene polymorphisms in melanoma.

J Transl Med 2012 Aug 21;10:170. Epub 2012 Aug 21.

Infectious Disease and Immunogenetics Section, Department of Transfusion Medicine, Clinical Center and trans-NIH Center for Human Immunology, National Institutes of Health, Bethesda, MD 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1479-5876-10-170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492128PMC
August 2012

Genetic ancestry, serum interferon-α activity, and autoantibodies in systemic lupus erythematosus.

J Rheumatol 2012 Jun 15;39(6):1238-40. Epub 2012 Apr 15.

Section of Rheumatology, Gwen Knapp Center for Lupus Research, University of Chicago, Chicago, IL 60637, USA.

View Article

Download full-text PDF

Source
http://www.jrheum.org/cgi/doi/10.3899/jrheum.111467
Publisher Site
http://dx.doi.org/10.3899/jrheum.111467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381952PMC
June 2012

Sex chromosome aneuploidies among men with systemic lupus erythematosus.

J Autoimmun 2012 May 6;38(2-3):J129-34. Epub 2011 Dec 6.

Department of Medicine, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaut.2011.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309073PMC
May 2012

Association of a functional IRF7 variant with systemic lupus erythematosus.

Arthritis Rheum 2011 Mar;63(3):749-54

University of California, Los Angeles, and Joint Molecular Rheumatology Laboratory of Institute of Health Sciences and Shanghai Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institutes for Biological Sciences, and Chinese Academy of Sciences, Shanghai, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/art.30193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063317PMC
March 2011

Genome-wide association scan of Dupuytren's disease.

J Hand Surg Am 2010 Dec 25;35(12):2039-45. Epub 2010 Oct 25.

Department of Arthritis and Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhsa.2010.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998563PMC
December 2010

Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies.

Nat Rev Genet 2009 05;10(5):285-90

Oklahoma Medical Research Foundation, 825 North East 13th Street, Oklahoma City, Oklahoma 73104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrg2571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737697PMC
May 2009

Genetic variation in the CRP promoter: association with systemic lupus erythematosus.

Hum Mol Genet 2008 Apr 8;17(8):1147-55. Epub 2008 Jan 8.

Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294-2182, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddn004DOI Listing
April 2008

Unraveling the genetics of systemic lupus erythematosus.

Springer Semin Immunopathol 2006 Oct 22;28(2):119-30. Epub 2006 Sep 22.

Department of Medicine, University of Oklahoma, Oklahoma City, OK, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00281-006-0040-5DOI Listing
October 2006

Evaluation of the genetic association of the PTPN22 R620W polymorphism in familial and sporadic systemic lupus erythematosus.

Arthritis Rheum 2006 Aug;54(8):2533-40

Oklahoma Medical Research Foundation, and Department of Veterans Affairs Medical Center, Oklahoma City, Oklahoma 73104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/art.21963DOI Listing
August 2006

An altered immune response to Epstein-Barr nuclear antigen 1 in pediatric systemic lupus erythematosus.

Arthritis Rheum 2006 Jan;54(1):360-8

Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, 825 NE 13th Street, Oklahoma City, OK 73104, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/art.21682
Publisher Site
http://dx.doi.org/10.1002/art.21682DOI Listing
January 2006

The mannose-binding lectin gene polymorphisms and systemic lupus erythematosus: two case-control studies and a meta-analysis.

Arthritis Rheum 2005 Dec;52(12):3966-74

Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/art.21484DOI Listing
December 2005

Proteasome degradation of GRK2 during ischemia and ventricular tachyarrhythmias in a canine model of myocardial infarction.

Am J Physiol Heart Circ Physiol 2005 Nov 1;289(5):H1960-7. Epub 2005 Jul 1.

Dept. of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpheart.00328.2005DOI Listing
November 2005

Linkage at 5q14.3-15 in multiplex systemic lupus erythematosus pedigrees stratified by autoimmune thyroid disease.

Arthritis Rheum 2005 Nov;52(11):3646-50

Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, OK 73104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/art.21413DOI Listing
November 2005

Structural availability influences the capacity of autoantigenic epitopes to induce a widespread lupus-like autoimmune response.

Proc Natl Acad Sci U S A 2004 Mar 26;101(10):3551-6. Epub 2004 Feb 26.

Oklahoma Medical Research Foundation, University of Oklahoma Health Sciences Center, and Veterans Affairs Medical Center, Oklahoma City, OK 73104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0306267101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC373500PMC
March 2004

Peptide mimics of a major lupus epitope of SmB/B'.

Ann N Y Acad Sci 2003 Apr;987:215-29

Arthritis and Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma 73104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1749-6632.2003.tb06051.xDOI Listing
April 2003

Anti-sm autoantibodies in systemic lupus target highly basic surface structures of complexed spliceosomal autoantigens.

J Immunol 2002 Feb;168(4):2054-62

Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.168.4.2054DOI Listing
February 2002