Kenneth K Chan

Kenneth K Chan

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Kenneth K Chan

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Combinatorial Antitumor Activity of Oxaliplatin with Epigenetic Modifying Agents, 5-Aza-CdR and FK228, in Human Gastric Cancer Cells.

Biomol Ther (Seoul) 2018 Nov;26(6):591-598

Department of Biomedicine & Health Science, Graduate School, The Catholic University of Korea, Seoul 06591, Republic of Korea.

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http://dx.doi.org/10.4062/biomolther.2018.061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254647PMC
November 2018

Aspiration Thrombectomy versus Conventional Catheter-Directed Thrombolysis as First-Line Treatment for Noniatrogenic Acute Lower Limb Ischemia.

J Vasc Interv Radiol 2018 05 22;29(5):607-613. Epub 2018 Mar 22.

Department of Vascular and Endovascular Surgery, Sir Charles Gairdner Hospital, Perth, Western Australia 6009, Australia; School of Public Health, Curtin University, Perth, Western Australia, Australia; Faculty of Health and Medical Sciences, University of Western Australia, Perth, Western Australia, Australia; Heart Research Institute, Harry Perkins Institute of Medical Research, Perth, Western Australia, Australia.

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http://dx.doi.org/10.1016/j.jvir.2017.11.030DOI Listing
May 2018

Differential association for N-acetyltransferase 2 genotype and phenotype with bladder cancer risk in Chinese population.

Oncotarget 2016 Jun;7(26):40012-40024

University of Pittsburgh Cancer Institute, and Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.18632/oncotarget.9475DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129988PMC
June 2016

CD33-Targeted Lipid Nanoparticles (aCD33LNs) for Therapeutic Delivery of GTI-2040 to Acute Myelogenous Leukemia.

Mol Pharm 2015 Jun 28;12(6):2010-8. Epub 2015 Apr 28.

†Division of Pharmaceutics, College of Pharmacy, ‡Division of Hematology-Oncology, §Molecular, Cellular and Developmental Biology Program, and ∥Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio 43210, United States.

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http://dx.doi.org/10.1021/mp5008212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962870PMC
June 2015

Increasing prevalence of hypertension among patients with thoracic aorta dissection: trends over eight decades--a structured meta-analysis.

Am J Hypertens 2014 Jul 12;27(7):907-17. Epub 2014 Feb 12.

University of British Columbia, Department of Medicine-Cardiology, Vancouver, British Columbia, Canada.

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https://academic.oup.com/ajh/article-lookup/doi/10.1093/ajh/
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http://dx.doi.org/10.1093/ajh/hpt293DOI Listing
July 2014

First-line beta-blockers versus other antihypertensive medications for chronic type B aortic dissection.

Cochrane Database Syst Rev 2014 Feb 26(2):CD010426. Epub 2014 Feb 26.

Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1002/14651858.CD010426.pub2DOI Listing
February 2014

Curcumin down-regulates DNA methyltransferase 1 and plays an anti-leukemic role in acute myeloid leukemia.

PLoS One 2013 13;8(2):e55934. Epub 2013 Feb 13.

Division of Hematology, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0055934PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572185PMC
August 2013

Reactivation of RASSF1A in breast cancer cells by curcumin.

Nutr Cancer 2012 12;64(8):1228-35. Epub 2012 Nov 12.

College of Pharmacy, Ohio State University, Columbus, Ohio 43210, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082258PMC
http://dx.doi.org/10.1080/01635581.2012.717682DOI Listing
May 2013

A liquid chromatography-tandem mass spectrometric method for quantification of curcumin-O-glucuronide and curcumin in human plasma.

J Chromatogr B Analyt Technol Biomed Life Sci 2012 Jul 26;900:89-93. Epub 2012 May 26.

Zhejiang Cancer Research Institute, Zhejiang Cancer Hospital, Hangzhou, Zhejiang Province 310022, China.

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http://dx.doi.org/10.1016/j.jchromb.2012.05.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387345PMC
July 2012

Synthetic microRNA cassette dosing: pharmacokinetics, tissue distribution and bioactivity.

Mol Pharm 2012 Jun 23;9(6):1638-44. Epub 2012 May 23.

Division of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210,United States.

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http://dx.doi.org/10.1021/mp2006483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977775PMC
June 2012

Cytochrome P4501A2 phenotype and bladder cancer risk: The Shanghai bladder cancer study.

Int J Cancer 2012 Mar 21;130(5):1174-83. Epub 2011 Jun 21.

Masonic Cancer Center, University of Minnesota, MN, USA.

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http://dx.doi.org/10.1002/ijc.26121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167995PMC
March 2012

Enhancement of curcumin oral absorption and pharmacokinetics of curcuminoids and curcumin metabolites in mice.

Cancer Chemother Pharmacol 2012 Mar 4;69(3):679-89. Epub 2011 Oct 4.

College of Pharmacy, The Ohio State University, Room 152, Riffe Building, 500 W. 12th Avenue, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1007/s00280-011-1749-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368221PMC
March 2012

Effects of human oral mucosal tissue, saliva, and oral microflora on intraoral metabolism and bioactivation of black raspberry anthocyanins.

Cancer Prev Res (Phila) 2011 Aug 10;4(8):1209-21. Epub 2011 May 10.

Division of Oral Maxillofacial Surgery, Pathology & Anesthesiology, College of Dentistry, 2191B Postle Hall, 305 W. 12th Ave, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-11-0040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151333PMC
August 2011

Kisspeptin resets the hypothalamic GnRH clock in men.

J Clin Endocrinol Metab 2011 Jun 6;96(6):E908-15. Epub 2011 Apr 6.

Harvard Reproductive Sciences Center and Reproductive Endocrine Unit, Department of Medicine, Massachusetts General Hospital, 55 Fruit Street, BHX 5, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1210/jc.2010-3046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100758PMC
June 2011

Phase I and pharmacokinetic study of erlotinib (OSI-774) in combination with docetaxel in squamous cell carcinoma of the head and neck (SSCHN).

Cancer Chemother Pharmacol 2011 Mar 19;67(3):579-86. Epub 2010 May 19.

Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, College of Medicine and The Ohio State University Medical Center, Columbus, OH, USA.

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http://link.springer.com/10.1007/s00280-010-1332-y
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http://dx.doi.org/10.1007/s00280-010-1332-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828747PMC
March 2011

Environmental tobacco smoke in relation to bladder cancer risk--the Shanghai bladder cancer study [corrected].

Cancer Epidemiol Biomarkers Prev 2010 Dec 15;19(12):3087-95. Epub 2010 Oct 15.

Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-10-0823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003610PMC
December 2010

A liquid chromatography-tandem mass spectrometric method for quantification of curcuminoids in cell medium and mouse plasma.

J Chromatogr B Analyt Technol Biomed Life Sci 2010 Nov 17;878(30):3045-51. Epub 2010 Sep 17.

College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1016/j.jchromb.2010.08.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975763PMC
November 2010

Targeted delivery of antisense oligodeoxynucleotide by transferrin conjugated pH-sensitive lipopolyplex nanoparticles: a novel oligonucleotide-based therapeutic strategy in acute myeloid leukemia.

Mol Pharm 2010 Feb;7(1):196-206

NSF Nanoscale Science and Engineering Center, Division of Pharmaceutics, College of Pharmacy, Department of Chemical and Biomolecular Engineering, The Comprehensive Cancer Center, and Division of Hematology and Oncology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, USA.

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http://dx.doi.org/10.1021/mp900205rDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342499PMC
February 2010

A LC-MS/MS method for the analysis of intracellular nucleoside triphosphate levels.

Pharm Res 2009 Jun 17;26(6):1504-15. Epub 2009 Mar 17.

College of Pharmacy, The Ohio State University, 500 W. 12th Avenue, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1007/s11095-009-9863-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071250PMC
June 2009

Curcumin is a potent DNA hypomethylation agent.

Bioorg Med Chem Lett 2009 Feb 14;19(3):706-9. Epub 2008 Dec 14.

Division of Pharmaceutics, College of Pharmacy, The Ohio State University, 500 W. 12th St., Columbus, OH 43210, USA.

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http://dx.doi.org/10.1016/j.bmcl.2008.12.041DOI Listing
February 2009

Enzyme kinetics of GTI-2040, a phosphorothioate oligonucleotide targeting ribonucleotide reductase.

Drug Metab Dispos 2008 Nov 24;36(11):2227-33. Epub 2008 Jul 24.

Division of Pharmaceutics, College of Pharmacy, Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1124/dmd.108.021295DOI Listing
November 2008

Metabolism of a sulfur-containing heteroarotionoid antitumor agent, SHetA2, using liquid chromatography/tandem mass spectrometry.

Rapid Commun Mass Spectrom 2008 Nov;22(21):3371-81

College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.

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http://doi.wiley.com/10.1002/rcm.3744
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http://dx.doi.org/10.1002/rcm.3744DOI Listing
November 2008

Genetic determinants in the metabolism of bladder carcinogens in relation to risk of bladder cancer.

Carcinogenesis 2008 Jul 9;29(7):1386-93. Epub 2008 Jun 9.

The Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1093/carcin/bgn136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720058PMC
July 2008

A phase I and pharmacokinetic study of weekly oxaliplatin followed by paclitaxel in patients with solid tumors.

Clin Cancer Res 2008 Jun;14(11):3434-40

Division of Hematology and Oncology, The Ohio State University, A434B Starling Loving Hall, 320 West 10th Avenue, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-4903DOI Listing
June 2008

Beta-cryptoxanthin and lung cancer in Shanghai, China--an examination of potential confounding with cigarette smoking using urinary cotinine as a biomarker for true tobacco exposure.

Nutr Cancer 2007 ;57(2):123-9

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1080/01635580701273998DOI Listing
September 2007

Quantification of valproic acid and its metabolite 2-propyl-4-pentenoic acid in human plasma using HPLC-MS/MS.

J Chromatogr B Analyt Technol Biomed Life Sci 2007 May 4;850(1-2):206-12. Epub 2006 Dec 4.

Division of Pharmaceutics, College of Pharmacy, The Ohio State University, OH 43210, USA.

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http://dx.doi.org/10.1016/j.jchromb.2006.11.027DOI Listing
May 2007

Community attitudes towards discriminatory practice against people with severe mental illness in Hong Kong.

Int J Soc Psychiatry 2007 Mar;53(2):159-74

Department of Social Work, Hong Kong Baptist University, Kowloon, Hong Kong.

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http://journals.sagepub.com/doi/10.1177/0020764006074556
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http://dx.doi.org/10.1177/0020764006074556DOI Listing
March 2007

Population pharmacokinetics of humanized monoclonal antibody HuCC49deltaCH2 and murine antibody CC49 in colorectal cancer patients.

J Clin Pharmacol 2007 Feb;47(2):227-37

Division of Pharmaceutics, College of Pharmacy, The Ohio State University, 232 Parks Hall, 500 West 12th Avenue, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1177/0091270006293758DOI Listing
February 2007

High performance liquid chromatographic analysis and preclinical pharmacokinetics of the heteroarotinoid antitumor agent, SHetA2.

Cancer Chemother Pharmacol 2006 Nov 14;58(5):561-9. Epub 2006 Mar 14.

College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1007/s00280-006-0211-zDOI Listing
November 2006

Pharmacokinetics of N-2-chloroethylaziridine, a volatile cytotoxic metabolite of cyclophosphamide, in the rat.

Cancer Chemother Pharmacol 2006 Oct 10;58(4):532-9. Epub 2006 Feb 10.

College of Pharmacy, The Ohio State University, Columbus, OH, 43210, USA.

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http://link.springer.com/10.1007/s00280-006-0196-7
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http://dx.doi.org/10.1007/s00280-006-0196-7DOI Listing
October 2006

In vivo metabolism and final disposition of a novel nonsteroidal androgen in rats and dogs.

Drug Metab Dispos 2006 Oct 30;34(10):1713-21. Epub 2006 Jun 30.

Division of Pharmaceutics, College of Pharmacy, The Ohio State University, 500 West 12th Ave., Columbus, OH 43210, USA.

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http://dx.doi.org/10.1124/dmd.106.009985DOI Listing
October 2006

Enzyme specific activation of benzoquinone ansamycin prodrugs using HuCC49DeltaCH2-beta-galactosidase conjugates.

J Med Chem 2006 Oct;49(21):6290-7

Division of Pharmaceutics, College of Pharmacy, Department of Chemistry and Biochemistry, Department of Surgery, The Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1021/jm060647fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596603PMC
October 2006

A phase II study of chloroquinoxaline sulfonamide (CQS) in patients with metastatic colorectal carcinoma (MCRC).

Invest New Drugs 2006 Jul;24(4):343-6

Division of Hematology and Oncology, Department of Medicine, The Ohio State University-James Cancer Hospital, Columbus, OH, USA.

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http://dx.doi.org/10.1007/510637-005-4827-3DOI Listing
July 2006

A specific picomolar hybridization-based ELISA assay for the determination of phosphorothioate oligonucleotides in plasma and cellular matrices.

Pharm Res 2006 Jun 25;23(6):1251-64. Epub 2006 May 25.

Division of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1007/s11095-006-0082-3DOI Listing
June 2006

The combination of the proteasome inhibitor bortezomib and the bcl-2 antisense molecule oblimersen sensitizes human B-cell lymphomas to cyclophosphamide.

Clin Cancer Res 2006 May;12(9):2902-11

Department of Medicine, Lymphoma, and Developmental Chemotherapy Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-05-0308DOI Listing
May 2006

Tandem mass spectrometric analysis of cyclophosphamide, ifosfamide and their metabolites.

Rapid Commun Mass Spectrom 2005 ;19(18):2581-90

Colleges of Pharmacy and Medicine and Public Health, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1002/rcm.2099DOI Listing
March 2006

Discovery of a daunorubicin analogue that exhibits potent antitumor activity and overcomes P-gp-mediated drug resistance.

J Med Chem 2006 Feb;49(3):932-41

Division of Pharmaceutics, College of Pharmacy, Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1021/jm050800qDOI Listing
February 2006

Characterization and quantification of Bcl-2 antisense G3139 and metabolites in plasma and urine by ion-pair reversed phase HPLC coupled with electrospray ion-trap mass spectrometry.

J Chromatogr B Analyt Technol Biomed Life Sci 2005 Oct 18;825(2):201-13. Epub 2005 Aug 18.

Division of Pharmaceutics, College of Pharmacy, Room no. 308, The Ohio State University, Comprehensive Cancer Center (OSU CCC), 410 W12th Ave., Columbus, OH 43210, USA.

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http://dx.doi.org/10.1016/j.jchromb.2005.05.049DOI Listing
October 2005

Investigating the SecY plug movement at the SecYEG translocation channel.

EMBO J 2005 Oct 8;24(19):3380-8. Epub 2005 Sep 8.

Department of Biochemistry & Molecular Biology, Faculty of Medicine, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1038/sj.emboj.7600804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1276166PMC
October 2005

Hormonal effect on psoriasis in pregnancy and post partum.

Arch Dermatol 2005 May;141(5):601-6

Department of Dermatology, University of California, Irvine 92697, USA.

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http://dx.doi.org/10.1001/archderm.141.5.601DOI Listing
May 2005

Efflux of depsipeptide FK228 (FR901228, NSC-630176) is mediated by P-glycoprotein and multidrug resistance-associated protein 1.

J Pharmacol Exp Ther 2005 Apr 5;313(1):268-76. Epub 2005 Jan 5.

Division of Pharmaceutics, College of Pharmacy, The Ohio State Univeristy, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1124/jpet.104.072033DOI Listing
April 2005

Cellular uptake and intracellular levels of the bcl-2 antisense g3139 in cultured cells and treated patients with acute myeloid leukemia.

Clin Cancer Res 2005 Apr;11(8):2998-3008

Division of Pharmaceutics, College of Medicine and Public Health, Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-04-1505DOI Listing
April 2005

Characterization of a novel two-finger variable reluctance gripper.

ISA Trans 2005 Apr;44(2):177-85

Department of Electrical Engineering, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.

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April 2005

Metabolism studies of the anti-tumor agent maytansine and its analog ansamitocin P-3 using liquid chromatography/tandem mass spectrometry.

J Mass Spectrom 2005 Mar;40(3):389-99

College of Pharmacy, Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1002/jms.800DOI Listing
March 2005

A phase 1 and pharmacodynamic study of depsipeptide (FK228) in chronic lymphocytic leukemia and acute myeloid leukemia.

Blood 2005 Feb 5;105(3):959-67. Epub 2004 Oct 5.

Department of Internal Medicine, Division of Hematology-Oncology, Starling Loving Hall, Rm 302, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1182/blood-2004-05-1693DOI Listing
February 2005

An API LC/MS/MS quantitation method for ansamitocin P-3 (AP3) and its preclinical pharmacokinetics.

J Pharm Biomed Anal 2004 Nov;36(4):815-21

College of Pharmacy, The Ohio State University, 410 W. 12th Avenue, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1016/j.jpba.2004.07.045DOI Listing
November 2004

Subnanogram on-line column-switching liquid chromatographic-tandem mass spectrometric quantification method for nelfinavir and methoxyphenol metabolite M1 in rat plasma.

J Chromatogr B Analyt Technol Biomed Life Sci 2004 Sep;809(1):1-7

College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1016/j.jchromb.2004.05.007DOI Listing
September 2004

Carotenoids/vitamin C and smoking-related bladder cancer.

Int J Cancer 2004 Jun;110(3):417-23

USC/Norris Comprehensive Cancer Center, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90089-9181, USA.

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http://dx.doi.org/10.1002/ijc.20104DOI Listing
June 2004

Recent developments in the maytansinoid antitumor agents.

Chem Pharm Bull (Tokyo) 2004 Jan;52(1):1-26

College of Pharmacy, The Ohio State University, 500 West 12th Avenue, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1248/cpb.52.1DOI Listing
January 2004

DNA sequence specificity for topoisomerase II poisoning by the quinoxaline anticancer drugs XK469 and CQS.

Mol Pharmacol 2003 Jun;63(6):1382-8

The Ohio State University, Department of Radiology, 103 Wiseman Hall, 400 West 12th Avenue, Columbus, OH 43210, USA.

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http://molpharm.aspetjournals.org/cgi/doi/10.1124/mol.63.6.1
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http://dx.doi.org/10.1124/mol.63.6.1382DOI Listing
June 2003

Identification of thiols and glutathione conjugates of depsipeptide FK228 (FR901228), a novel histone protein deacetylase inhibitor, in the blood.

Rapid Commun Mass Spectrom 2003 ;17(8):757-66

College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1002/rcm.976DOI Listing
May 2003

Permanent hair dyes and bladder cancer: risk modification by cytochrome P4501A2 and N-acetyltransferases 1 and 2.

Carcinogenesis 2003 Mar;24(3):483-9

USC/Norris Comprehensive Cancer Center, Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90033-0800, USA.

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http://dx.doi.org/10.1093/carcin/24.3.483DOI Listing
March 2003

Dosing sequence-dependent pharmacokinetic interaction of oxaliplatin with paclitaxel in the rat.

Cancer Chemother Pharmacol 2002 Dec 16;50(6):445-53. Epub 2002 Oct 16.

College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1007/s00280-002-0531-6DOI Listing
December 2002

Arylamine exposures and bladder cancer risk.

Mutat Res 2002 Sep;506-507:21-8

Keck School of Medicine, USC/Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1016/s0027-5107(02)00148-3DOI Listing
September 2002

Pharmacokinetics of oxaliplatin (NSC 266046) alone and in combination with paclitaxel in cancer patients.

Cancer Chemother Pharmacol 2002 May 20;49(5):367-74. Epub 2002 Feb 20.

College of Pharmacy, Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1007/s00280-002-0426-6DOI Listing
May 2002

Bradykinin antagonist dimer, CU201, inhibits the growth of human lung cancer cell lines in vitro and in vivo and produces synergistic growth inhibition in combination with other antitumor agents.

Clin Cancer Res 2002 May;8(5):1280-7

Lung Cancer Program of the University of Colorado Cancer Center, University of Colorado Health Sciences Center, Denver 80262, USA.

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May 2002

Electrospray LC-MS/MS quantitation, stability, and preliminary pharmacokinetics of bradykinin antagonist polypeptide B201 (NSC 710295) in the mouse.

J Pharm Biomed Anal 2002 May;28(3-4):601-12

College of Pharmacy The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1016/s0731-7085(01)00697-5DOI Listing
May 2002