Kenneth G C Smith

Kenneth G C Smith

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Kenneth G C Smith

Publications by authors named "Kenneth G C Smith"

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B Cell Fcγ Receptor IIb Modulates Atherosclerosis in Male and Female Mice by Controlling Adaptive Germinal Center and Innate B-1-Cell Responses.

Arterioscler Thromb Vasc Biol 2019 Jul 16;39(7):1379-1389. Epub 2019 May 16.

From the Division of Cardiovascular Medicine (J.B.-C., A.F., T.B., L.M., D.T., M.N., J.H., M.B., J.L., Z.M., A.P.S.), Department of Medicine, University of Cambridge, United Kingdom.

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http://dx.doi.org/10.1161/ATVBAHA.118.312272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636804PMC
July 2019

FcγRIIb differentially regulates pre-immune and germinal center B cell tolerance in mouse and human.

Nat Commun 2019 04 29;10(1):1970. Epub 2019 Apr 29.

The Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, CB2 OXY, England, UK.

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http://dx.doi.org/10.1038/s41467-019-09434-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488660PMC
April 2019

Antibody repertoire analysis in polygenic autoimmune diseases.

Immunology 2018 09 16;155(1):3-17. Epub 2018 Apr 16.

Department of Medicine, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1111/imm.12927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099162PMC
September 2018

Reduced monocyte and macrophage TNFSF15/TL1A expression is associated with susceptibility to inflammatory bowel disease.

PLoS Genet 2018 09 10;14(9):e1007458. Epub 2018 Sep 10.

Department of Medicine, University of Cambridge School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.

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https://dx.plos.org/10.1371/journal.pgen.1007458
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http://dx.doi.org/10.1371/journal.pgen.1007458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130856PMC
September 2018

Belimumab in kidney transplantation: an experimental medicine, randomised, placebo-controlled phase 2 trial.

Lancet 2018 06 14;391(10140):2619-2630. Epub 2018 Jun 14.

Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge, UK; National Institute of Health Research (NIHR) Cambridge Biomedical Research Centre, Cambridge, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01406736183098
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http://dx.doi.org/10.1016/S0140-6736(18)30984-XDOI Listing
June 2018

Peripheral Immune Cell Populations Associated with Cognitive Deficits and Negative Symptoms of Treatment-Resistant Schizophrenia.

PLoS One 2016 31;11(5):e0155631. Epub 2016 May 31.

NIHR Cambridge Biomedical Research Centre, Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge, Cambridge, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0155631PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887013PMC
July 2017

Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network.

Genome Med 2016 07 19;8(1):76. Epub 2016 Jul 19.

Department of Medicine and Cambridge Institute for Medical Research, The University of Cambridge, Box 139, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, UK.

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http://dx.doi.org/10.1186/s13073-016-0329-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4952362PMC
July 2016

The Contribution of Transcriptomics to Biomarker Development in Systemic Vasculitis and SLE.

Curr Pharm Des 2015 ;21(17):2225-35

Cambridge Institute for Medical Research, and Department of Medicine, The University of Cambridge, Box 139, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0XY, United Kingdom.

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http://dx.doi.org/10.2174/1381612821666150313130256DOI Listing
May 2016

FcγRIIB and autoimmunity.

Immunol Rev 2016 Jan;269(1):194-211

Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge, UK.

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http://dx.doi.org/10.1111/imr.12368DOI Listing
January 2016

Regulatory T cells and control of the germinal centre response.

Arthritis Res Ther 2014 ;16(5):471

Lymphocyte Signalling and Development, Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289055PMC
August 2015

Long-term follow-up of patients who received repeat-dose rituximab as maintenance therapy for ANCA-associated vasculitis.

Rheumatology (Oxford) 2015 Jul 3;54(7):1153-60. Epub 2014 Dec 3.

Department of Medicine, University of Cambridge School of Clinical Medicine, Vasculitis and Lupus Service, Addenbrooke's Hospital, Cambridge, UK, Department of Clinical and Experimental Medicine, University of Parma, Italy and Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK Department of Medicine, University of Cambridge School of Clinical Medicine, Vasculitis and Lupus Service, Addenbrooke's Hospital, Cambridge, UK, Department of Clinical and Experimental Medicine, University of Parma, Italy and Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.

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http://dx.doi.org/10.1093/rheumatology/keu452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473766PMC
July 2015

How many memories does it take to make an SLE flare?

Nat Immunol 2015 Jul;16(7):685-7

Department of Medicine and Cambridge Institute of Medical Research, University of Cambridge School of Clinical Medicine, Cambridge, UK.

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http://dx.doi.org/10.1038/ni.3209DOI Listing
July 2015

T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection.

Nature 2015 Jul 29;523(7562):612-6. Epub 2015 Jun 29.

1] Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK [2] Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK.

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http://dx.doi.org/10.1038/nature14468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623162PMC
July 2015

Emerging concepts in the pathogenesis of antineutrophil cytoplasmic antibody-associated vasculitis.

Curr Opin Rheumatol 2015 Mar;27(2):197-203

aDepartment of Medicine, University of Cambridge bCambridge Institute of Medical Research, Cambridge, UK.

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http://dx.doi.org/10.1097/BOR.0000000000000145DOI Listing
March 2015

Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes.

Nat Med 2014 Dec 10;20(12):1458-63. Epub 2014 Nov 10.

Laboratory of Systems Biology, Lymphocyte Biology Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1038/nm.3709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283039PMC
December 2014

FcγRIIb inhibits immune complex-induced VEGF-A production and intranodal lymphangiogenesis.

Proc Natl Acad Sci U S A 2014 Dec 4;111(50):17971-6. Epub 2014 Dec 4.

Department of Medicine, Cambridge Institute for Medical Research, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge CB2 0XY, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1413915111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273345PMC
December 2014

Randomized trial of enteric-coated mycophenolate sodium versus mycophenolate mofetil in multi-system autoimmune disease.

Clin Kidney J 2014 Dec 16;7(6):562-8. Epub 2014 Sep 16.

Vasculitis and Lupus Clinic , Addenbrooke's Hospital , Cambridge , UK ; Department of Medicine , University of Cambridge School of Clinical Medicine , Cambridge , UK.

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http://dx.doi.org/10.1093/ckj/sfu096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389135PMC
December 2014

Human T-follicular helper and T-follicular regulatory cell maintenance is independent of germinal centers.

Blood 2014 Oct 15;124(17):2666-74. Epub 2014 Sep 15.

Cambridge Institute for Medical Research and Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom;

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http://dx.doi.org/10.1182/blood-2014-07-585976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208282PMC
October 2014

Comparison of gene expression microarray data with count-based RNA measurements informs microarray interpretation.

BMC Genomics 2014 Aug 4;15:649. Epub 2014 Aug 4.

Cambridge Institute for Medical Research and Department of Medicine, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1186/1471-2164-15-649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143561PMC
August 2014

The immunopathology of ANCA-associated vasculitis.

Semin Immunopathol 2014 Jul 24;36(4):461-78. Epub 2014 Jul 24.

The Cambridge Institute for Medical Research and the Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge, UK,

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http://link.springer.com/10.1007/s00281-014-0436-6
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http://dx.doi.org/10.1007/s00281-014-0436-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118034PMC
July 2014

The effect of rituximab therapy on immunoglobulin levels in patients with multisystem autoimmune disease.

BMC Musculoskelet Disord 2014 May 25;15:178. Epub 2014 May 25.

Department of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1186/1471-2474-15-178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038057PMC
May 2014

Prognosis in autoimmune and infectious disease: new insights from genetics.

Clin Transl Immunology 2014 May 16;3(5):e15. Epub 2014 May 16.

Cambridge Institute for Medical Research, Cambridge Biomedical Campus , Cambridge, UK ; Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus , Cambridge, UK.

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http://dx.doi.org/10.1038/cti.2014.8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232069PMC
May 2014

Siglec-G deficiency leads to more severe collagen-induced arthritis and earlier onset of lupus-like symptoms in MRL/lpr mice.

J Immunol 2014 Apr 5;192(7):2994-3002. Epub 2014 Mar 5.

Division of Genetics, Department of Biology, University of Erlangen-Nürnberg, 91058 Erlangen, Germany;

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http://dx.doi.org/10.4049/jimmunol.1303367DOI Listing
April 2014

Important role for FcγRIIB on B lymphocytes for mucosal antigen-induced tolerance and Foxp3+ regulatory T cells.

J Immunol 2013 Oct 13;191(8):4412-22. Epub 2013 Sep 13.

University of Gothenburg Vaccine Institute, SE405 30 Göteborg, Sweden;

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1301324
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http://dx.doi.org/10.4049/jimmunol.1301324DOI Listing
October 2013

MiR-210 is induced by Oct-2, regulates B cells, and inhibits autoantibody production.

J Immunol 2013 Sep 19;191(6):3037-3048. Epub 2013 Aug 19.

Cambridge Institute for Medical Research and Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0XY, UK.

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http://dx.doi.org/10.4049/jimmunol.1301289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162006PMC
September 2013

Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway.

Cell 2013 Sep 12;155(1):57-69. Epub 2013 Sep 12.

Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK; Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.

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http://dx.doi.org/10.1016/j.cell.2013.08.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790457PMC
September 2013

L31. A GWAS in ANCA-associated vasculitis: will genetics help re-define clinical classification?

Presse Med 2013 Apr 11;42(4 Pt 2):589-91. Epub 2013 Mar 11.

Cambridge Institute for Medical Research and Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0XY, United Kingdom.

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http://dx.doi.org/10.1016/j.lpm.2013.02.303DOI Listing
April 2013

Increased red cell turnover in a line of CD22-deficient mice is caused by Gpi1c: a model for hereditary haemolytic anaemia.

Eur J Immunol 2012 Dec 16;42(12):3212-22. Epub 2012 Oct 16.

Cambridge Institute for Medical Research and Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge, UK.

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http://doi.wiley.com/10.1002/eji.201242633
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http://dx.doi.org/10.1002/eji.201242633DOI Listing
December 2012

CD22 and autoimmune disease.

Int Rev Immunol 2012 Oct;31(5):363-78

Charité University Medicine Berlin, CC12, Dept. Medicine/Rheumatology and Clinical Immunology and German Rheumatism Research Center Berlin (DRFZ), Berlin, Germany.

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http://dx.doi.org/10.3109/08830185.2012.709890DOI Listing
October 2012

Magnetic resonance imaging with hyperpolarized [1,4-(13)C2]fumarate allows detection of early renal acute tubular necrosis.

Proc Natl Acad Sci U S A 2012 Aug 26;109(33):13374-9. Epub 2012 Jul 26.

Cambridge Institute for Medical Research and Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge CB2 0XY, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1205539109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3421192PMC
August 2012

Gene expression profiling of CD8+ T cells predicts prognosis in patients with Crohn disease and ulcerative colitis.

J Clin Invest 2011 Oct 26;121(10):4170-9. Epub 2011 Sep 26.

Cambridge Institute for Medical Research, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.

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http://dx.doi.org/10.1172/JCI59255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196314PMC
October 2011

Wild immunology: converging on the real world.

Ann N Y Acad Sci 2011 Oct;1236:17-29

Centre for Immunity, Infection and Evolution, Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Ashworth Laboratories, Kings Buildings, Edinburgh, United Kingdom.

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http://doi.wiley.com/10.1111/j.1749-6632.2011.06251.x
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http://dx.doi.org/10.1111/j.1749-6632.2011.06251.xDOI Listing
October 2011

Foxp3+ follicular regulatory T cells control the germinal center response.

Nat Med 2011 Jul 24;17(8):975-82. Epub 2011 Jul 24.

Cambridge Institute for Medical Research and the Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1038/nm.2425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182542PMC
July 2011

Local renal autoantibody production in lupus nephritis.

J Am Soc Nephrol 2011 Feb 18;22(2):296-305. Epub 2010 Nov 18.

Cambridge Institute for Medical Research and the Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge CB2 2OY, United Kingdom.

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http://www.jasn.org/cgi/doi/10.1681/ASN.2010050515
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http://dx.doi.org/10.1681/ASN.2010050515DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029902PMC
February 2011

Genetic susceptibility to systemic lupus erythematosus protects against cerebral malaria in mice.

Proc Natl Acad Sci U S A 2011 Jan 27;108(3):1122-7. Epub 2010 Dec 27.

Laboratories of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USA.

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http://dx.doi.org/10.1073/pnas.1017996108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024697PMC
January 2011

Long-term efficacy and safety of rituximab in refractory and relapsing systemic lupus erythematosus.

Nephrol Dial Transplant 2010 Nov 11;25(11):3586-92. Epub 2010 May 11.

Vasculitis and Lupus Clinic, Renal Unit, Addenbrooke's Hospital, Cambridge University, Hills Road, UK.

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http://dx.doi.org/10.1093/ndt/gfq256DOI Listing
November 2010

The contribution of genetic variation and infection to the pathogenesis of ANCA-associated systemic vasculitis.

Arthritis Res Ther 2010 15;12(1):202. Epub 2010 Feb 15.

Cambridge Institute for Medical Research and Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0XY, UK.

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http://arthritis-research.biomedcentral.com/articles/10.1186
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http://dx.doi.org/10.1186/ar2928DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875655PMC
August 2010

Copy number, linkage disequilibrium and disease association in the FCGR locus.

Hum Mol Genet 2010 Aug 27;19(16):3282-94. Epub 2010 May 27.

Department of Medicine, Cambridge Institute for Medical Research, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0XY, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908468PMC
http://dx.doi.org/10.1093/hmg/ddq216DOI Listing
August 2010

Efficient inhibition of miR-155 function in vivo by peptide nucleic acids.

Nucleic Acids Res 2010 Jul 11;38(13):4466-75. Epub 2010 Mar 11.

Medical Research Council, Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.

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http://dx.doi.org/10.1093/nar/gkq160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910044PMC
July 2010

A CD8+ T cell transcription signature predicts prognosis in autoimmune disease.

Nat Med 2010 May 18;16(5):586-91, 1p following 591. Epub 2010 Apr 18.

Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge Institute for Medical Research, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1038/nm.2130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504359PMC
May 2010

FcgammaRIIB in autoimmunity and infection: evolutionary and therapeutic implications.

Nat Rev Immunol 2010 May;10(5):328-43

Cambridge Institute for Medical Research and the Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge CB2 0XY, UK.

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http://dx.doi.org/10.1038/nri2762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148599PMC
May 2010

A defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus.

Proc Natl Acad Sci U S A 2010 Apr 12;107(17):7881-5. Epub 2010 Apr 12.

Department of Medicine, Cambridge Institute for Medical Research, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge CB2 0XY, United Kingdom.

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http://www.pnas.org/lookup/doi/10.1073/pnas.0915133107
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http://dx.doi.org/10.1073/pnas.0915133107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867866PMC
April 2010

FcgammaRIIB, FcgammaRIIIB, and systemic lupus erythematosus.

Ann N Y Acad Sci 2010 Jan;1183:69-88

Cambridge Institute for Medical Research and Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1111/j.1749-6632.2009.05132.xDOI Listing
January 2010

Confirmation of the genetic association of CTLA4 and PTPN22 with ANCA-associated vasculitis.

BMC Med Genet 2009 Dec 1;10:121. Epub 2009 Dec 1.

Cambridge Institute for Medical Research, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB20XY, UK.

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http://dx.doi.org/10.1186/1471-2350-10-121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224698PMC
December 2009

Low-affinity Fcgamma receptors, autoimmunity and infection.

Expert Rev Mol Med 2009 Aug 13;11:e24. Epub 2009 Aug 13.

Cambridge Institute for Medical Research and Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge, CB2 0XY, UK.

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http://www.journals.cambridge.org/abstract_S1462399409001161
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http://dx.doi.org/10.1017/S1462399409001161DOI Listing
August 2009

What is the value of mycophenolate mofetil as induction and maintenance therapy in lupus nephritis?

Curr Opin Rheumatol 2009 May;21(3):256-61

Renal Unit, Vasculitis and Lupus Clinic, Box 118, Addenbrooke's Hospital, Hills Road, Cambridge CB2 OQQ, UK.

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May 2009

Contrasting genetic association of IL2RA with SLE and ANCA-associated vasculitis.

BMC Med Genet 2009 Mar 5;10:22. Epub 2009 Mar 5.

Cambridge Institute for Medical Research, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0XY, UK.

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http://dx.doi.org/10.1186/1471-2350-10-22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662820PMC
March 2009

Complement abnormalities in acquired lipodystrophy revisited.

J Clin Endocrinol Metab 2009 Jan 14;94(1):10-6. Epub 2008 Oct 14.

Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, United Kingdom.

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http://dx.doi.org/10.1210/jc.2008-1703DOI Listing
January 2009

Dependence of surface monoclonal antibody binding on dynamic changes in FcgammaRIIb expression.

Immunology 2008 Jul 24;124(3):412-8. Epub 2008 Jan 24.

Department of Medicine, Cambridge Institute for Medical Research, Addenbrooke's Hospital, Cambridge, UK.

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http://doi.wiley.com/10.1111/j.1365-2567.2007.02791.x
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http://dx.doi.org/10.1111/j.1365-2567.2007.02791.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440835PMC
July 2008

Distinct cell-specific control of autoimmunity and infection by FcgammaRIIb.

J Exp Med 2008 Apr 24;205(4):883-95. Epub 2008 Mar 24.

Cambridge Institute for Medical Research and the Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge CB2 2OY, England, UK.

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http://dx.doi.org/10.1084/jem.20072565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292226PMC
April 2008

CD22: an inhibitory enigma.

Immunology 2008 Mar 7;123(3):314-25. Epub 2007 Dec 7.

Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Addenbrooke's Hospital, Cambridge CB2 0XY, United Kingdom.

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http://doi.wiley.com/10.1111/j.1365-2567.2007.02752.x
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http://dx.doi.org/10.1111/j.1365-2567.2007.02752.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2433339PMC
March 2008

The nervous spleen: The nervous spleen.

Immunol Cell Biol 2008 Jan;86(1):1-2

Department of Medicine, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2XY, UK.

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http://doi.wiley.com/10.1038/sj.icb.7100150
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http://dx.doi.org/10.1038/sj.icb.7100150DOI Listing
January 2008

B cells in glomerulonephritis: focus on lupus nephritis.

Semin Immunopathol 2007 Nov 18;29(4):337-53. Epub 2007 Oct 18.

Division of Renal Medicine, Department of Medicine and Cambridge Institute for Medical Research, University of Cambridge, Lab 5.15, Box 139 Addenbrooke's Hospital, Cambridge, CB2 2XY, UK.

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http://dx.doi.org/10.1007/s00281-007-0092-1DOI Listing
November 2007

Control of Rta expression critically determines transcription of viral and cellular genes following gammaherpesvirus infection.

J Gen Virol 2007 Jun;88(Pt 6):1689-97

Cambridge Institute for Medical Research and the Department of Medicine, Wellcome Trust/MRC Building, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 2XY, UK.

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http://dx.doi.org/10.1099/vir.0.82548-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2884955PMC
June 2007

FcgammaRIIb controls bone marrow plasma cell persistence and apoptosis.

Nat Immunol 2007 Apr 18;8(4):419-29. Epub 2007 Feb 18.

Cambridge Institute for Medical Research and the Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge CB2 2OY, UK.

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http://dx.doi.org/10.1038/ni1440DOI Listing
April 2007

Systemic lupus erythematosus-associated defects in the inhibitory receptor FcgammaRIIb reduce susceptibility to malaria.

Proc Natl Acad Sci U S A 2007 Apr 13;104(17):7169-74. Epub 2007 Apr 13.

Cambridge Institute for Medical Research and Department of Medicine, University of Cambridge, Cambridge, United Kingdom.

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http://www.sciencemag.org/cgi/doi/10.1126/science.1133515
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