Kenneth C Williams

Kenneth C Williams

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Kenneth C Williams

Kenneth C Williams

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Animal models of HIV-associated disease of the central nervous system.

Handb Clin Neurol 2018 ;152:41-53

Department of Biology, Boston College, Chestnut Hill, MA, United States. Electronic address:

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http://dx.doi.org/10.1016/B978-0-444-63849-6.00004-9DOI Listing
September 2018

Monocyte subsets exhibit transcriptional plasticity and a shared response to interferon in SIV-infected rhesus macaques.

J Leukoc Biol 2018 01 14;103(1):141-155. Epub 2017 Dec 14.

Department of Biology, Boston College, Chestnut Hill, Massachusetts, USA.

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http://dx.doi.org/10.1002/JLB.4A0217-047RDOI Listing
January 2018

HDL Cholesterol Efflux Capacity in Newly Diagnosed HIV and Effects of Antiretroviral Therapy.

J Clin Endocrinol Metab 2017 11;102(11):4250-4259

Lipid Metabolism Unit/Center for Computational and Integrative Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114.

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http://dx.doi.org/10.1210/jc.2017-01334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673269PMC
November 2017

Direct Targeting of Macrophages With Methylglyoxal-Bis-Guanylhydrazone Decreases SIV-Associated Cardiovascular Inflammation and Pathology.

J Acquir Immune Defic Syndr 2017 04;74(5):583-592

*Department of Biology, Boston College, Chestnut Hill, MA; †Cornell University College of Veterinary Medicine, Ithaca, NY; and ‡Department of Pathology and Laboratory Medicine, UCSF, San Francisco, CA.

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http://Insights.ovid.com/crossref?an=00126334-201704150-0001
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http://dx.doi.org/10.1097/QAI.0000000000001297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370195PMC
April 2017

Effects of pitavastatin and pravastatin on markers of immune activation and arterial inflammation in HIV.

AIDS 2017 03;31(6):797-806

aMassachusetts General Hospital, Program in Nutrition and Metabolism and Harvard Medical School, Boston bDepartment of Biology, Boston College, Chestnut Hill, Massachusetts cDepartment of Neuroscience, Temple University School of Medicine, Philadelphia, Pennsylvania dMount Sinai Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, New York eKOWA Pharmaceuticals America Inc., Montgomery, Alabama, USA.

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http://Insights.ovid.com/crossref?an=00002030-201703270-0000
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http://dx.doi.org/10.1097/QAD.0000000000001427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382495PMC
March 2017

Correction for Rife et al., Evolution of Neuroadaptation in the Periphery and Purifying Selection in the Brain Contribute to Compartmentalization of Simian Immunodeficiency Virus (SIV) in the Brains of Rhesus Macaques with SIV-Associated Encephalitis.

J Virol 2016 10 12;90(19):8947. Epub 2016 Sep 12.

Department of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, Florida, USA Emerging Pathogens Institute, University of Florida, Gainesville, Florida, USA.

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http://dx.doi.org/10.1128/JVI.01304-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021433PMC
October 2016

High expression levels of BLyS/BAFF by blood dendritic cells and granulocytes are associated with B-cell dysregulation in SIV-infected rhesus macaques.

PLoS One 2015 24;10(6):e0131513. Epub 2015 Jun 24.

Laboratoire d'immunogénétique, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Canada; Département de Microbiologie, Infectiologie et Immunologie de l'Université de Montréal, Montréal, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0131513PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479440PMC
April 2016

Editorial: Identification of in vivo markers for human polarized macrophages: a need that's finally met.

J Leukoc Biol 2015 Oct;98(4):449-50

*Department of Biology, Boston College, Chestnut Hill, Massachusetts, USA; and Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, Virginia, USA

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http://dx.doi.org/10.1189/jlb.1CE0615-233RRDOI Listing
October 2015

Tracking the Emergence of Host-Specific Simian Immunodeficiency Virus env and nef Populations Reveals nef Early Adaptation and Convergent Evolution in Brain of Naturally Progressing Rhesus Macaques.

J Virol 2015 Aug 3;89(16):8484-96. Epub 2015 Jun 3.

Department of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, Florida, USA Emerging Pathogens Institute, University of Florida, Gainesville, Florida, USA

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http://dx.doi.org/10.1128/JVI.01010-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524235PMC
August 2015

Macrophage Polarization in AIDS: Dynamic Interface between Anti-Viral and Anti-Inflammatory Macrophages during Acute and Chronic Infection.

J Clin Cell Immunol 2015 Jun 24;6(3). Epub 2015 Jun 24.

Department of Biology, Boston College, Chestnut Hill, MA, 02467, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612489PMC
June 2015

Soluble CD163 is associated with shortened telomere length in HIV-infected patients.

J Acquir Immune Defic Syndr 2014 Dec;67(4):414-418

Program in Nutritional Metabolism (K.F., S.S., E.P., J.L., S.K.G.), Massachusetts General Hospital and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1097/QAI.0000000000000329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213298PMC
December 2014

Spatiotemporal dynamics of simian immunodeficiency virus brain infection in CD8+ lymphocyte-depleted rhesus macaques with neuroAIDS.

J Gen Virol 2014 Dec 9;95(Pt 12):2784-95. Epub 2014 Sep 9.

Department of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL, USA Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA

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http://dx.doi.org/10.1099/vir.0.070318-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233634PMC
December 2014

The importance of monocytes and macrophages in HIV pathogenesis, treatment, and cure.

AIDS 2014 Sep;28(15):2175-87

aDepartment of Biology, Boston College, Chestnut Hill, Massachusetts, USA bCentre for Biomedical Research, Burnet Institute cDepartment of Infectious Diseases, Monash University dInfectious Diseases Unit, The Alfred Hospital, Melbourne, Victoria, Australia.

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http://pdfs.journals.lww.com/aidsonline/2014/09240/The_impor
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http://dx.doi.org/10.1097/QAD.0000000000000408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331181PMC
September 2014

Identification and characterization of a macrophage-tropic SIV envelope glycoprotein variant in blood from early infection in SIVmac251-infected macaques.

Virology 2014 Jun 8;458-459:53-68. Epub 2014 May 8.

Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Neurology, Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.virol.2014.03.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112485PMC
June 2014

Monocyte/macrophages and their role in HIV neuropathogenesis.

Immunol Rev 2013 Jul;254(1):102-13

Department of Biology, Boston College, Chestnut Hill, MA 02467, USA.

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http://dx.doi.org/10.1111/imr.12068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704190PMC
July 2013

Arterial inflammation in patients with HIV.

JAMA 2012 Jul;308(4):379-86

MR-PET-CT Program and Department of Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1001/jama.2012.6698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724172PMC
July 2012

Immunophenotyping of lymphocyte, monocyte and dendritic cell subsets in normal rhesus macaques by 12-color flow cytometry: clarification on DC heterogeneity.

J Immunol Methods 2010 Aug 30;360(1-2):119-28. Epub 2010 Jun 30.

Department of Biology, Boston College, Higgins Hall 468, 140 Commonwealth Avenue, Chestnut Hill, MA 02467, USA.

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http://dx.doi.org/10.1016/j.jim.2010.06.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930593PMC
August 2010

Evaluation of a 12-color flow cytometry panel to study lymphocyte, monocyte, and dendritic cell subsets in humans.

Cytometry A 2010 May;77(5):410-9

Department of Biology, Boston College, Chestnut Hill, Massachusetts 02467, USA.

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http://dx.doi.org/10.1002/cyto.a.20859DOI Listing
May 2010

The level of monocyte turnover predicts disease progression in the macaque model of AIDS.

Blood 2009 Oct 21;114(14):2917-25. Epub 2009 Apr 21.

Division of Immunology, Tulane National Primate Research Center, Tulane University Health Science Center, Covington, LA 70433, USA .

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http://dx.doi.org/10.1182/blood-2009-02-204263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756202PMC
October 2009

Dynamics of Simian immunodeficiency virus-specific cytotoxic T-cell responses in tissues.

J Med Primatol 2003 Aug;32(4-5):194-200

Tulane National Primate Research Center, Tulane University Health Sciences Center, Covington, LA 70433, USA.

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August 2003

Global dysfunction of CD4 T-lymphocyte cytokine expression in simian-human immunodeficiency virus/SIV-infected monkeys is prevented by vaccination.

J Virol 2003 Apr;77(8):4695-702

Division of Viral Pathogenesis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC152134PMC
http://dx.doi.org/10.1128/jvi.77.8.4695-4702.2003DOI Listing
April 2003

Central nervous system damage, monocytes and macrophages, and neurological disorders in AIDS.

Annu Rev Neurosci 2002 27;25:537-62. Epub 2002 Mar 27.

Department of Medicine, Harvard Medical School Division of Viral Pathogenesis Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1146/annurev.neuro.25.112701.142822DOI Listing
October 2002

Characterization of an in vitro rhesus macaque blood-brain barrier.

J Neuroimmunol 2002 Oct;131(1-2):98-103

New England Regional Primate Research Center, Harvard Medical School, Southborough, MA 01772-9102, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635499PMC
http://dx.doi.org/10.1016/s0165-5728(02)00256-4DOI Listing
October 2002