Publications

Prognostic Implications of Changes in Albumin Following Left Ventricular Assist Device Implantation in Patients With Severe Heart Failure.
Am J Cardiol 2017 Dec 30;120(11):2003-2007. Epub 2017 Aug 30.
Department of Medicine, Cardiovascular Division, University of Pennsylvania, Philadelphia, Pennsylvania; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:




Detailed Echocardiographic Phenotyping in Breast Cancer Patients: Associations With Ejection Fraction Decline, Recovery, and Heart Failure Symptoms Over 3 Years of Follow-Up.
Circulation 2017 Apr 19;135(15):1397-1412. Epub 2017 Jan 19.
From Department of Pediatrics, Division of Cardiology, The Children's Hospital of Philadelphia, PA (H.K.N.); Department of Biostatistics and Epidemiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia (B. Finkelman, B. French, B.K.); and Department of Medicine, Division of Cardiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia (B. Finkelman, T.P., D.H., A.M.S., K.B.M., B.K.).

Development of dilated cardiomyopathy and impaired calcium homeostasis with cardiac-specific deletion of ESRRβ.
Am J Physiol Heart Circ Physiol 2017 Apr 27;312(4):H662-H671. Epub 2017 Jan 27.
Cardiovascular Institute, Department of Medicine, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, Massachusetts.

Pharmacokinetics and Pharmacodynamics of Inorganic Nitrate in Heart Failure With Preserved Ejection Fraction.
Circ Res 2017 Mar 7;120(7):1151-1161. Epub 2016 Dec 7.
From the Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia (P.Z., V.T., H.S.-C., M.B., J.A.B., S.V., K.B.M., T.P.C., J.A.C.); Rowan University School of Osteopathic Medicine, Stratford, NJ (L.T.); Children's Hospital of Philadelphia Research Institute, PA (P.-T.D., H.I.); Division of Nephrology/Hypertension, Perelman School of Medicine, University of Pennsylvania, Philadelphia (R.R.T.); Office of Nursing Research, School of Nursing, University of Pennsylvania, Philadelphia (J.C.); Departments of Kinesiology, Anatomy, and Physiology, Kansas State University, Manhattan (D.C.P.).


Right ventricular response to pulsatile load is associated with early right heart failure and mortality after left ventricular assist device.
J Heart Lung Transplant 2017 Jan 24;36(1):97-105. Epub 2016 Jun 24.
Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

Intravenous Allogeneic Mesenchymal Stem Cells for Nonischemic Cardiomyopathy: Safety and Efficacy Results of a Phase II-A Randomized Trial.
Circ Res 2017 Jan 16;120(2):332-340. Epub 2016 Nov 16.
From the Division of Cardiology, Department of Medicine, Stony Brook University, NY (J.B., H.A.S.); MedStar Heart and Vascular Institute, MedStar Washington Hospital Center, Washington, DC (S.E.E., M.J.L.); Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC (S.J.G., R.J.K.); Division of Cardiology, Department of Medicine, Emory University, Atlanta, GA (A.A.Q., R.T.C.); CardioCell LLC, San Diego, CA (S.S.); Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (A.S.A., J.E.W.); Stemedica Cell Technologies Inc, San Diego, CA (N.I.T.); Department of Biostatistics and Bioinformatics, Emory University, Atlanta, GA (Y.-A.K.); Division of Cardiology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia (K.B.M.); and Center for Cardiovascular Innovation, Northwestern University Feinberg School of Medicine, Chicago, IL (M.G.).

Effect of Heart Failure With Preserved Ejection Fraction on Nitric Oxide Metabolites.
Am J Cardiol 2016 Dec 15;118(12):1855-1860. Epub 2016 Sep 15.
Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.


Comparing Raman and fluorescence lifetime spectroscopy from human atherosclerotic lesions using a bimodal probe.
J Biophotonics 2016 Sep 22;9(9):958-66. Epub 2016 Mar 22.
Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich-Schiller University Jena, Helmholtzweg 4, 07743, Jena, Germany.



Comparison of Causes of Death After Heart Transplantation in Patients With Left Ventricular Ejection Fractions ≤35% Versus >35.
Am J Cardiol 2016 Apr 28;117(8):1322-6. Epub 2016 Jan 28.
Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:

Evidence for Intramyocardial Disruption of Lipid Metabolism and Increased Myocardial Ketone Utilization in Advanced Human Heart Failure.
Circulation 2016 Feb 27;133(8):706-16. Epub 2016 Jan 27.
From Cardiovascular Institute University of Pennsylvania Perelman School of Medicine, Smilow Translational Research Center, Philadelphia, PA (K.C.B., J.B., A.J., K.B.M., J.E.R.); A.J. Drexel Autism Institute, Drexel University, Philadelphia, PA (N.W.S.); and Center of Cancer Pharmacology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA (M.A., C.M., A.J.W., L.L.W., I.A.B.).


Fluorescence Lifetime Imaging Combined with Conventional Intravascular Ultrasound for Enhanced Assessment of Atherosclerotic Plaques: an Ex Vivo Study in Human Coronary Arteries.
J Cardiovasc Transl Res 2015 Jun 1;8(4):253-63. Epub 2015 May 1.
Department of Biomedical Engineering, University of California Davis, 451 E. Health Sciences Drive, Davis, CA, 95616, USA.

Effects of sildenafil on ventricular and vascular function in heart failure with preserved ejection fraction.
Circ Heart Fail 2015 May 17;8(3):533-41. Epub 2015 Mar 17.
From the Department of Medicine, Division of Cardiology, Mayo Clinic, Rochester, MN (B.A.B., H.C., G.L., M.M.R.); Department of Medicine, Massachusetts General Hospital, Boston (G.D.L., M.J.S.); Department of Medicine, Duke Clinical Research Institute, Durham, NC (S.E.M.); Department of Medicine, Cardiology Unit, University of Vermont College of Medicine, Burlington (M.L.W.); Department of Medicine, Michael E. DeBakey VA Medical Center and Department of Medicine, Baylor College of Medicine, Houston, TX (A.D.); and Department of Medicine, University of Pennsylvania, Translational Research Center, Philadelphia (K.B.M.).

Effects of Xanthine Oxidase Inhibition in Hyperuricemic Heart Failure Patients: The Xanthine Oxidase Inhibition for Hyperuricemic Heart Failure Patients (EXACT-HF) Study.
Circulation 2015 May 14;131(20):1763-71. Epub 2015 Apr 14.
From Brigham and Women's Hospital, Harvard Medical School, Boston, MA (M.M.G.); Duke University Medical Center, Durham, NC (K.J.A., G.M.F., C.M.O., S.E.M., K.L.L., A.F.H.); Mayo Clinic, Rochester, MN (M.M.R.); Michael E. DeBakey VA Medical Center, Baylor College of Medicine, Houston, TX (A.D.); Ottawa Heart Institute, Ontario, Canada (H.H.); Emory University, Atlanta, GA (J.B.); Cleveland Clinic, OH (W.H.W.T.); MetroHealth Campus of Case Western Reserve University, Cleveland, OH (M.E.D.); University of Vermont, Burlington (M.M.L.); Washington University, St. Louis, MO (D.L.M.); Hennepin County Medical Center, Minneapolis, MN (S.R.G.); Morehouse School of Medicine, Atlanta, GA (E.O.O.); Christiana Care Health System, Newark, DE (M.T.S.); University of Pennsylvania, Philadelphia (K.B.M., T.P.C.); Tufts Medical Center, Boston, MA (M.A.K.); Massachusetts General Hospital, Boston (M.J.S.); and National Heart, Lung, and Blood Institute, Bethesda, MD (M.R.S.).


RNA-Seq identifies novel myocardial gene expression signatures of heart failure.
Genomics 2015 Feb 17;105(2):83-9. Epub 2014 Dec 17.
Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, United States. Electronic address:

Effect of inorganic nitrate on exercise capacity in heart failure with preserved ejection fraction.
Circulation 2015 Jan 22;131(4):371-80; discussion 380. Epub 2014 Dec 22.
From the Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Perelman School of Medicine, Philadelphia (P.Z., P.S.-K., P.K., K.B.M., T.P.C., J.A.C.); Division of Cardiology, Philadelphia Veterans Affairs Medical Center, Philadelphia, PA (D.R., P.S.-K., S.G., R.B., J.A.C.); Children's Hospital of Philadelphia Research Institute, Philadelphia, PA (P.-T.D., H.I.); Division of Nephrology/Hypertension. Perelman School of Medicine, University of Pennsylvania, Philadelphia (R.R.T.); and Departments of Kinesiology, Anatomy, and Physiology, Kansas State University, Manhattan (D.C.P.).

Cardioprotection by controlling hyperamylinemia in a "humanized" diabetic rat model.
J Am Heart Assoc 2014 Aug 21;3(4). Epub 2014 Aug 21.
Department of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, KY (S.D., S.S., F.D.) Saha Cardiovascular Research Center, University of Kentucky, Lexington, KY (S.D., F.D.).

A bioengineered hydrogel system enables targeted and sustained intramyocardial delivery of neuregulin, activating the cardiomyocyte cell cycle and enhancing ventricular function in a murine model of ischemic cardiomyopathy.
Circ Heart Fail 2014 Jul 5;7(4):619-26. Epub 2014 Jun 5.
From the Department of Cardiothoracic Surgery, Stanford University, CA (J.E.C., J.W.M., Y.S., J.B.P., B.B.E., Y.J.W.); and Departments of Surgery, Division of Cardiovascular Surgery (J.E.C., J.W.M., C.M.B., A.T., A.S.F., G.H., W.H., P.A.), Bioengineering (B.P.P., M.S.D., J.A.B.), and Cardiology (A.M., K.B.M.), University of Pennsylvania, Philadelphia.

GLP-1 agonist therapy for advanced heart failure with reduced ejection fraction: design and rationale for the functional impact of GLP-1 for heart failure treatment study.
Circ Heart Fail 2014 Jul;7(4):673-9
From the Perelman School of Medicine, University of Pennsylvania, Philadelphia (K.B.M., T.P.C.); Duke Clinical Research Institute, Durham, NC (K.J.A., A.F.H.); Mayo Clinic, Rochester, MN (M.M.R.); Division of Cardiovascular Sciences, National Heart, Lung and Blood Institute, Bethesda, MD (M.R.S.); and Harvard Medical School, Boston, MA (E.B.).


Gene expression and genetic variation in human atria.
Heart Rhythm 2014 Feb 28;11(2):266-71. Epub 2013 Oct 28.
Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Massachusetts; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts; Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts.


BET bromodomains mediate transcriptional pause release in heart failure.
Cell 2013 Aug;154(3):569-82
Case Cardiovascular Research Institute, Department of Medicine, Case Western Reserve University School of Medicine, and Harrington Heart & Vascular Institute, University Hospitals Case Medical Center, Cleveland, OH 44106, USA.


Klf15 deficiency is a molecular link between heart failure and aortic aneurysm formation.
Sci Transl Med 2010 Apr;2(26):26ra26
Case Cardiovascular Research Institute, Department of Medicine, Harrington-McLaughlin Heart and Vascular Institute, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, OH 44106, USA.


Evidence for coregulation of myocardial gene expression by MEF2 and NFAT in human heart failure.
Circ Cardiovasc Genet 2009 Jun 31;2(3):212-9. Epub 2009 Mar 31.
Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.


Sex and age dimorphism of myocardial gene expression in nonischemic human heart failure.
Circ Cardiovasc Genet 2008 Dec 9;1(2):117-25. Epub 2008 Dec 9.
Lillehei Heart Institute, Division of Cardiology, Developmental Biology Center, University of Minnesota, Minneapolis, USA.

Reduced effects of BAY K 8644 on L-type Ca2+ current in failing human cardiac myocytes are related to abnormal adrenergic regulation.
Am J Physiol Heart Circ Physiol 2008 May 21;294(5):H2257-67. Epub 2008 Mar 21.
Cardiovascular Research Center and Department of Physiology, Temple University School of Medicine, 3420 North Broad Street, Philadelphia, PA 19140, USA.

Cardiac dysfunction and heart failure are associated with abnormalities in the subcellular distribution and amounts of oligomeric muscle LIM protein.
Am J Physiol Heart Circ Physiol 2007 Jan 8;292(1):H259-69. Epub 2006 Sep 8.
Dept. of Physiology and Biophysics (M/C 901 Univ. of Illinois at Chicago, 835 S. Wolcott Ave., Chicago IL 60612-7342, USA.


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