Kenji Tamura

Kenji Tamura

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Kenji Tamura

Kenji Tamura

Publications by authors named "Kenji Tamura"

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A Comparative Study of Longitudinal Toxicities of Cytotoxic Drugs, Molecularly Targeted Agents, Immunomodulatory Drugs, and Cancer Vaccines.

Clin Pharmacol Ther 2019 Oct 29;106(4):803-809. Epub 2019 Apr 29.

Investigational Drug Branch, Cancer Therapy Evaluation Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institute of Health, Rockville, Maryland, USA.

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http://dx.doi.org/10.1002/cpt.1442DOI Listing
October 2019

Brain metastasis-related microRNAs in patients with advanced breast cancer.

PLoS One 2019 11;14(10):e0221538. Epub 2019 Oct 11.

Department of Breast and Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0221538PLOS
October 2019

Therapeutic preferability of gemcitabine for ARID1A-deficient ovarian clear cell carcinoma.

Gynecol Oncol 2019 Oct 8. Epub 2019 Oct 8.

Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan; Molecular Oncology, The Jikei University Graduate School of Medicine, Tokyo, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00908258193155
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http://dx.doi.org/10.1016/j.ygyno.2019.10.002DOI Listing
October 2019

Feasibility of initial treatment in elderly patients with ovarian cancer in Japan: a retrospective study.

Int J Clin Oncol 2019 Sep 15;24(9):1111-1118. Epub 2019 Apr 15.

Breast and Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1007/s10147-019-01449-3DOI Listing
September 2019

Real-world data on initial treatment strategies for older adult patients with endometrial cancer in Japan.

Cancer Chemother Pharmacol 2019 Sep 4. Epub 2019 Sep 4.

Department of Breast and Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1007/s00280-019-03938-8DOI Listing
September 2019

Rosette-like Layered Double Hydroxides: Adsorbent Materials for the Removal of Anionic Pollutants from Water.

ACS Appl Mater Interfaces 2019 Aug 26;11(31):27954-27963. Epub 2019 Jul 26.

National Institute for Materials Science , 1-1 Namiki , Tsukuba , Ibaraki 305-0044 , Japan.

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http://dx.doi.org/10.1021/acsami.9b08719DOI Listing
August 2019

Comparison of Sample Preparation Methods for Multielements Analysis of Olive Oil by ICP-MS.

Methods Protoc 2019 Aug 19;2(3). Epub 2019 Aug 19.

Faculty of Life and Environmental Sciences, University of Tsukuba, Ibaraki 305-8572, Japan.

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http://dx.doi.org/10.3390/mps2030072DOI Listing
August 2019

Platinum-free interval affects efficacy of following treatment for platinum-refractory or -resistant ovarian cancer.

Cancer Chemother Pharmacol 2019 Jul 13;84(1):33-39. Epub 2019 Apr 13.

Breast and Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1007/s00280-019-03834-1DOI Listing
July 2019

Interregional traceability of Tunisian olive oils to the provenance soil by multielemental fingerprinting and chemometrics.

Food Chem 2019 Jun 19;283:656-664. Epub 2019 Jan 19.

Environmental Soil Chemistry Laboratory, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8577, Japan; Faculty of Life and Environmental Sciences, University of Tsukuba, Ibaraki 305-8572, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S03088146193015
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http://dx.doi.org/10.1016/j.foodchem.2019.01.082DOI Listing
June 2019

Short-Term Effects of Carbonaceous Components in PM on Pulmonary Function: A Panel Study of 37 Chinese Healthy Adults.

Int J Environ Res Public Health 2019 06 26;16(13). Epub 2019 Jun 26.

Department of Epidemiology and Health Statistics, School of Health Sciences, Wuhan University, Wuhan 430071, China.

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http://dx.doi.org/10.3390/ijerph16132259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651261PMC
June 2019

Invasive breast cancers in adolescent and young adult women show more aggressive immunohistochemical and clinical features than those in women aged 40-44 years.

Breast Cancer 2019 May 11;26(3):386-396. Epub 2018 Dec 11.

Department of Breast and Medical Oncology, National Cancer Center Hospital, Tokyo 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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http://dx.doi.org/10.1007/s12282-018-00937-0DOI Listing
May 2019

Biomarker discordance between primary breast cancer and bone or bone marrow metastases.

Jpn J Clin Oncol 2019 May;49(5):426-430

Department of Breast and Medical Oncology, National Cancer Center Hospital.

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http://dx.doi.org/10.1093/jjco/hyz018DOI Listing
May 2019

Insights Into Breast Cancer in the East vs the West: A Review.

JAMA Oncol 2019 May 16. Epub 2019 May 16.

Department of Haematology-Oncology, National University Cancer Institute, Singapore.

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http://oncology.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamaoncol.2019.0620DOI Listing
May 2019

Mathematical analysis of gefitinib resistance of lung adenocarcinoma caused by MET amplification.

Biochem Biophys Res Commun 2019 Apr 26;511(3):544-550. Epub 2019 Feb 26.

Division of Molecular Pathology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2019.02.086DOI Listing
April 2019

Serum miRNA-based Prediction of Axillary Lymph Node Metastasis in Breast Cancer.

Clin Cancer Res 2019 Mar 27;25(6):1817-1827. Epub 2018 Nov 27.

Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, Tokyo, Japan.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-1414DOI Listing
March 2019

Isoflavone Intake in Early Pregnancy and Hypospadias in the Japan Environment and Children's Study.

Urology 2019 02 15;124:229-236. Epub 2018 Nov 15.

Centre for Health and Environmental Risk Research, National Institute for Environmental Studies, Tsukuba, Japan.

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http://dx.doi.org/10.1016/j.urology.2018.11.008DOI Listing
February 2019

Trastuzumab emtansine plus pertuzumab in Japanese patients with HER2-positive metastatic breast cancer: a phase Ib study.

Breast Cancer 2019 Jan 23;26(1):39-46. Epub 2018 Jul 23.

Department of Breast and Medical Oncology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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http://dx.doi.org/10.1007/s12282-018-0887-zDOI Listing
January 2019

Fish consumption in early pregnancy and congenital gastrointestinal tract atresia in the Japan Environment and Children's Study.

Br J Nutr 2019 Jan 29;121(1):100-108. Epub 2018 Oct 29.

1Centre for Health and Environmental Risk Research,National Institute for Environmental Studies,16-2 Onogawa,Tsukuba,Ibaraki 305-8506,Japan.

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http://dx.doi.org/10.1017/S0007114518002842DOI Listing
January 2019

A novel prediction score for predicting the baseline risk of recurrence of stage I-II endometrial carcinoma.

J Gynecol Oncol 2019 Jan 2;30(1):e8. Epub 2018 Oct 2.

Department of Breast and Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.3802/jgo.2019.30.e8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304400PMC
January 2019

Six-year monitoring of the vertical distribution of radiocesium in three forest soils after the Fukushima Dai-ichi Nuclear Power Plant accident.

J Environ Radioact 2018 Dec 30;192:172-180. Epub 2018 Jun 30.

Faculty of Life and Environmental Sciences, University of Tsukuba, Japan.

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http://dx.doi.org/10.1016/j.jenvrad.2018.06.015DOI Listing
December 2018

Cesium desorption behavior of weathered biotite in Fukushima considering the actual radioactive contamination level of soils.

J Environ Radioact 2018 Oct 15;190-191:81-88. Epub 2018 May 15.

Department of Earth and Planetary Science, Graduate School of Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

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http://dx.doi.org/10.1016/j.jenvrad.2018.05.006DOI Listing
October 2018

SMARCB-1 deficient squamous cell carcinoma of a mediastinal cyst.

Pathol Int 2018 Oct 14;68(10):563-566. Epub 2018 Sep 14.

Department of Pathology and Clinical Laboratories, National Cancer Center Hospital, Tokyo, Japan.

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http://doi.wiley.com/10.1111/pin.12720
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http://dx.doi.org/10.1111/pin.12720DOI Listing
October 2018

Six-year monitoring of the vertical distribution of radiocesium in three forest soils after the Fukushima Dai-ichi Nuclear Power Plant accident.

J Environ Radioact 2018 Oct 28:105811. Epub 2018 Oct 28.

Faculty of Life and Environmental Sciences, University of Tsukuba, Japan.

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http://dx.doi.org/10.1016/j.jenvrad.2018.09.009DOI Listing
October 2018

Efficacy of capecitabine in patients with locally advanced or metastatic breast cancer with or without prior treatment with fluoropyrimidine: a retrospective study.

Cancer Chemother Pharmacol 2018 08 5;82(2):275-283. Epub 2018 Jun 5.

Department of Breast and Medical Oncology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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http://dx.doi.org/10.1007/s00280-018-3617-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060805PMC
August 2018

Symptom management: the utility of regional cooling for hand-foot syndrome induced by pegylated liposomal doxorubicin in ovarian cancer.

Support Care Cancer 2018 Jul 25;26(7):2161-2166. Epub 2018 Jan 25.

Department of Breast and Medical Oncology, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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http://dx.doi.org/10.1007/s00520-018-4054-zDOI Listing
July 2018

Efficacy and Safety of Pazopanib for Recurrent or Metastatic Solitary Fibrous Tumor.

Oncology 2018 3;94(6):340-344. Epub 2018 Apr 3.

Department of Breast and Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1159/000486623DOI Listing
June 2018

Utility of Bayesian Single-Arm Design in New Drug Application for Rare Cancers in Japan: A Case Study of Phase 2 Trial for Sarcoma.

Ther Innov Regul Sci 2018 05 8;52(3):334-338. Epub 2017 Sep 8.

2 Department of Breast and Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1177/2168479017728989DOI Listing
May 2018

TERT promoter hotspot mutations in breast cancer.

Breast Cancer 2018 May 8;25(3):292-296. Epub 2017 Dec 8.

Department of Breast and Medical Oncology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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http://dx.doi.org/10.1007/s12282-017-0825-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906518PMC
May 2018

Downward migration of radiocesium in an abandoned paddy soil after the Fukushima Dai-ichi Nuclear Power Plant accident.

J Environ Radioact 2018 Feb 14;182:157-164. Epub 2017 Dec 14.

Center for Research in Isotopes and Environmental Dynamics, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8572, Japan.

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http://dx.doi.org/10.1016/j.jenvrad.2017.11.034DOI Listing
February 2018

Solid state vibrational circular dichroism towards molecular recognition: chiral metal complexes intercalated in a clay mineral.

Phys Chem Chem Phys 2018 Jan;20(5):3141-3147

Department of Chemistry, Graduate School of Science and Engineering, Ehime University, Matsuyama 790-8577, Japan.

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http://dx.doi.org/10.1039/c7cp05114jDOI Listing
January 2018

Potential utility of a longitudinal relative dose intensity of molecularly targeted agents in phase 1 dose-finding trials.

Cancer Sci 2018 Jan 8;109(1):207-214. Epub 2017 Dec 8.

Investigational Drug Branch, Cancer Therapy Evaluation Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institute of Health, Rockville, MD, USA.

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http://doi.wiley.com/10.1111/cas.13436
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http://dx.doi.org/10.1111/cas.13436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765308PMC
January 2018

Baseline risk of recurrence in stage I-II endometrial carcinoma.

J Gynecol Oncol 2018 Jan;29(1):e9

Department of Breast and Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.3802/jgo.2018.29.e9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709535PMC
January 2018

Amrubicin Monotherapy for Patients with Platinum-Pretreated Non-Gastrointestinal Non-Pancreatic Extrapulmonary Neuroendocrine Carcinoma.

Oncology 2017 19;93(3):177-182. Epub 2017 May 19.

Department of Medical Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan.

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http://dx.doi.org/10.1159/000475669DOI Listing
December 2017

SHISA2 enhances the aggressive phenotype in prostate cancer through the regulation of WNT5A expression.

Oncol Lett 2017 Dec 28;14(6):6650-6658. Epub 2017 Sep 28.

Department of Urology, Kochi Medical School, Kochi University, Nankoku, Kochi 783-8505, Japan.

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http://dx.doi.org/10.3892/ol.2017.7099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754837PMC
December 2017

Visualization of HER2-specific breast cancer intratumoral heterogeneity using Cu-DOTA-trastuzumab PET.

Eur J Nucl Med Mol Imaging 2017 11 3;44(12):2146-2147. Epub 2017 Aug 3.

Department of Breast and Medical Oncology, National Cancer Center Hospital, Tsukiji 5-1-1, Chuo-Ku, Tokyo, 104-0045, Japan.

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http://dx.doi.org/10.1007/s00259-017-3781-6DOI Listing
November 2017

The Prognostic Impact of the Pathological Response to Neoadjuvant Dose-Dense Therapy for Ovarian Carcinoma.

Int J Gynecol Cancer 2017 11;27(9):1850-1855

*Department of Medical Oncology, Chiba University, Chiba; and Departments of †Breast and Medical Oncology, ‡Pathology, §Pharmacy, and ∥Gynecology, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1097/IGC.0000000000001107DOI Listing
November 2017

LC-MS bioanalysis of Trastuzumab and released emtansine using nano-surface and molecular-orientation limited (nSMOL) proteolysis and liquid-liquid partition in plasma of Trastuzumab emtansine-treated breast cancer patients.

J Pharm Biomed Anal 2017 Oct 19;145:33-39. Epub 2017 Jun 19.

Leading Technology of Bioanalysis and Protein Chemistry, SHIMADZU Corporation, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2017.06.032DOI Listing
October 2017

Evaluation of the heterogeneous tissue distribution of erlotinib in lung cancer using matrix-assisted laser desorption ionization mass spectrometry imaging.

Sci Rep 2017 10 3;7(1):12622. Epub 2017 Oct 3.

Division of Molecular Pharmacology, National Cancer Center Research Institute, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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http://dx.doi.org/10.1038/s41598-017-13025-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626687PMC
October 2017

Do all patients in the phase I oncology trials need to be hospitalized? Domestic but outstanding issues for globalization of drug development in Japan.

Int J Clin Oncol 2017 Aug 14;22(4):780-785. Epub 2017 Mar 14.

Department of Experimental Therapeutics, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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http://dx.doi.org/10.1007/s10147-017-1108-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533862PMC
August 2017

Allred score is a promising predictor of prognosis and medroxyprogesterone acetate efficacy in patients with endometrial cancer.

Cancer Chemother Pharmacol 2017 Jul 24;80(1):127-134. Epub 2017 May 24.

Department of Breast and Medical Oncology, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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http://dx.doi.org/10.1007/s00280-017-3342-5DOI Listing
July 2017

Surveillance of protocol deviations in Japanese oncology registration trials: a single institute experience.

Invest New Drugs 2017 06 1;35(3):392-396. Epub 2017 Feb 1.

Clinical Trial Coordination and Support Office, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1007/s10637-017-0434-3DOI Listing
June 2017

Prognostic Significance of Progesterone Receptor Expression in Estrogen-Receptor Positive, HER2-Negative, Node-Negative Invasive Breast Cancer With a Low Ki-67 Labeling Index.

Clin Breast Cancer 2017 02 25;17(1):41-47. Epub 2016 Jun 25.

Department of Breast and Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.clbc.2016.06.012DOI Listing
February 2017

Drug induced interstitial lung disease in oncology phase I trials.

Cancer Sci 2016 Dec;107(12):1830-1836

Investigational Drug Branch, Cancer Therapy Evaluation Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institute of Health, Rockville, Maryland, USA.

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http://doi.wiley.com/10.1111/cas.13087
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http://dx.doi.org/10.1111/cas.13087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198943PMC
December 2016

Comprehensive screening of target molecules by next-generation sequencing in patients with malignant solid tumors: guiding entry into phase I clinical trials.

Mol Cancer 2016 11 16;15(1):73. Epub 2016 Nov 16.

Department of Experimental Therapeutics, Exploratory Oncology Research & Clinical Center, National Cancer Center, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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http://dx.doi.org/10.1186/s12943-016-0553-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112718PMC
November 2016

[Undifferentiated Prostate Cancer Treated with Radiation Therapy].

Hinyokika Kiyo 2016 Nov;62(11):599-604

The Department of Urology, Kochi Medical School, Kochi University.

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http://dx.doi.org/10.14989/ActaUrolJap_62_11_599DOI Listing
November 2016

Feasibility of dose-dense paclitaxel/carboplatin therapy in elderly patients with ovarian, fallopian tube, or peritoneal cancer.

Cancer Chemother Pharmacol 2016 10 13;78(4):745-52. Epub 2016 Aug 13.

Department of Breast and Clinical Oncology, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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http://dx.doi.org/10.1007/s00280-016-3100-0DOI Listing
October 2016

Safety and tolerability of the olaparib tablet formulation in Japanese patients with advanced solid tumours.

Cancer Chemother Pharmacol 2016 Sep 15;78(3):525-31. Epub 2016 Jul 15.

Department of Gastroenterology, National Hospital Organization Hokkaido Cancer Center, Hokkaido, Japan.

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http://dx.doi.org/10.1007/s00280-016-3106-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010592PMC
September 2016

Phase 1 study of abemaciclib, an inhibitor of CDK 4 and 6, as a single agent for Japanese patients with advanced cancer.

Cancer Chemother Pharmacol 2016 Aug 16;78(2):281-8. Epub 2016 Jun 16.

Department of Experimental Therapeutics, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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http://dx.doi.org/10.1007/s00280-016-3085-8DOI Listing
August 2016

[Molecular target therapy].

Authors:
Kenji Tamura

Nihon Rinsho 2016 May;74 Suppl 3:226-33

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May 2016