Kenan Onel

Kenan Onel

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Kenan Onel

Kenan Onel

Publications by authors named "Kenan Onel"

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Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes.

Genet Epidemiol 2019 10 13;43(7):844-863. Epub 2019 Aug 13.

Center for Neuroengineering and Therapeutics, Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/gepi.22242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763347PMC
October 2019

Precision oncology: lessons learned and challenges for the future.

Cancer Manag Res 2019 7;11:7525-7536. Epub 2019 Aug 7.

The Icahn School of Medicine at Mount Sinai, Department of Genetics and Genomic Sciences, New York, NY, USA.

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http://dx.doi.org/10.2147/CMAR.S201326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698584PMC
August 2019

Comparing ethnicity-based and expanded carrier screening methods at a single fertility center reveals significant differences in carrier rates and carrier couple rates.

Genet Med 2019 06 16;21(6):1400-1406. Epub 2018 Oct 16.

Department of Obstetrics and Gynecology, Northwell Health, Division of Reproductive Endocrinology, Manhasset, NY, USA.

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http://www.nature.com/articles/s41436-018-0331-y
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http://dx.doi.org/10.1038/s41436-018-0331-yDOI Listing
June 2019

Choosing an expanded carrier screening panel: comparing two panels at a single fertility centre.

Reprod Biomed Online 2019 Feb 14;38(2):225-232. Epub 2018 Dec 14.

Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, Northwell Health, 300 Community Dr, Manhasset NY 11030, USA; Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, 500 Hofstra Blvd, empstead NY 11549, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14726483183060
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http://dx.doi.org/10.1016/j.rbmo.2018.11.018DOI Listing
February 2019

Increased risk of colon cancer and osteogenic sarcoma in Diamond-Blackfan anemia.

Blood 2018 11 28;132(20):2205-2208. Epub 2018 Sep 28.

Division of Hematology/Oncology and Stem Cell Transplantation, Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.

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http://www.bloodjournal.org/lookup/doi/10.1182/blood-2018-05
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http://dx.doi.org/10.1182/blood-2018-05-848937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238192PMC
November 2018

Genome-Wide Association Study to Identify Susceptibility Loci That Modify Radiation-Related Risk for Breast Cancer After Childhood Cancer.

J Natl Cancer Inst 2017 11;109(11)

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD; Department of Epidemiology and Cancer Control, Division of Cancer Survivorship, Department of Oncology, Department of Biostatistics, Hartwell Center for Bioinformatics and Biotechnology, and Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN; Cancer Genomics Research Laboratory, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD; Departments of Medicine, Pediatrics, and Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY; Section of Hematology, Oncology and Stem Cell Transplantation, Department of Pediatrics, University of Chicago, Chicago, IL; Nationwide Children's Hospital and the Ohio State University School of Medicine, Columbus, OH; Department of Pediatrics, University of Minnesota, Minneapolis, MN; Information Management Services, Inc., Calverton, MD; Cancer Prevention and Clinical Statistics Programs and Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA; Department of Genetics and Department of Radiation Physics, The University of Texas at MD Anderson Cancer Center, Houston, TX; Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Institute for Cancer Outcomes and Survivorship, University of Alabama at Birmingham, Birmingham, AL.

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http://dx.doi.org/10.1093/jnci/djx058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059172PMC
November 2017

Integrative genetic analysis suggests that skin color modifies the genetic architecture of melanoma.

PLoS One 2017 3;12(10):e0185730. Epub 2017 Oct 3.

Department of Pediatrics, Hofstra Northwell School of Medicine, Hempstead, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0185730PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626488PMC
October 2017

Evaluation of Genetic Predisposition for MYCN-Amplified Neuroblastoma.

J Natl Cancer Inst 2017 10;109(10)

Affiliations of authors: Section of Hematology/Oncology, Department of Pediatrics (EAH, MAA, ADS, SLV, SLC), Section of Genetic Medicine, Department of Medicine (BES), and Institute for Genomics and Systems Biology, Center for Data Intensive Science (BES), University of Chicago, Chicago, IL; Division of Oncology and Center for Childhood Cancer Research and Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA (ZV, MD, LM, JMM, SJD); Department of Pediatrics and Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA (JMM, SJD); Department of Pediatrics, Hofstra-Northwell School of Medicine and The Feinstein Institute for Medical Research, Manhasset, NY (KO).

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http://dx.doi.org/10.1093/jnci/djx093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279278PMC
October 2017

The genetics of breast cancer risk in the post-genome era: thoughts on study design to move past BRCA and towards clinical relevance.

Breast Cancer Res 2016 10 3;18(1):99. Epub 2016 Oct 3.

Department of Pediatrics, The University of Chicago, Chicago, IL, 60637, USA.

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http://dx.doi.org/10.1186/s13058-016-0759-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048663PMC
October 2016

Breast Cancer Risk in Childhood Cancer Survivors Without a History of Chest Radiotherapy: A Report From the Childhood Cancer Survivor Study.

J Clin Oncol 2016 Mar 23;34(9):910-8. Epub 2015 Dec 23.

Tara O. Henderson and Kenan Onel, University of Chicago, Chicago, IL; Chaya S. Moskowitz, Joanne F. Chou, Chau T. Dang, Danielle Novetsky Friedman, Dana Barnea, Elena Lorenzi, and Kevin C. Oeffinger, Memorial Sloan Kettering Cancer Center, New York, NY; Angela R. Bradbury, University of Pennsylvania, Philadelphia, PA; Joseph Phillip Neglia, University of Minnesota, Minneapolis, MN; Smita Bhatia, University of Alabama, Birmingham, AL; Louise C. Strong and Marilyn Stovall, MD Anderson Cancer Center, Houston, TX; Lisa B. Kenney and Lisa R. Diller, Dana-Farber Cancer Institute/Children's Hospital Boston, Boston, MA; Elena Lorenzi, Humanitas Clinical and Research Center, Rozzano, Milan, Italy; Sue Hammond, Nationwide Children's Hospital, Columbus, OH; Wendy M. Leisenring, Fred Hutchinson Cancer Research Center, Seattle, WA; and Leslie L. Robison and Gregory T. Armstrong, St Jude Children's Research Hospital, Memphis, TN.

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http://dx.doi.org/10.1200/JCO.2015.62.3314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871997PMC
March 2016

Whole-exome Sequence Analysis Implicates Rare Il17REL Variants in Familial and Sporadic Inflammatory Bowel Disease.

Inflamm Bowel Dis 2016 Jan;22(1):20-7

*Department of Pediatrics and †Center for Research Informatics, The University of Chicago, Chicago, Illinois; ‡Northern Institute for Cancer Research, Newcastle University, Newcastle-upon-Tyne, United Kingdom; §Meyerhoff Inflammatory Bowel Disease Center, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland; ‖Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland; ¶F. Widjaja Family Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California; **Department of Genetics and Genomic Sciences and ††Zane Cohen Centre for Digestive Diseases, Department of Medicine, Mount Sinai Hospital, The University of Toronto, Toronto, Ontario, Canada; and ‡‡Department of Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1097/MIB.0000000000000610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679526PMC
January 2016

The rising incidence of second cancers: patterns of occurrence and identification of risk factors for children and adults.

Am Soc Clin Oncol Educ Book 2014 :e57-67

From the Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, MD; Department of Pediatrics, The University of Chicago, Chicago, IL; and Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN.

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http://dx.doi.org/10.14694/EdBook_AM.2014.34.e57DOI Listing
December 2015

A Review of Fanconi Anemia for the Practicing Pediatrician.

Pediatr Ann 2015 Oct;44(10):444-5, 448, 450 passim

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http://dx.doi.org/10.3928/00904481-20151012-11DOI Listing
October 2015

Integrated genomic analysis suggests MLL3 is a novel candidate susceptibility gene for familial nasopharyngeal carcinoma.

Cancer Epidemiol Biomarkers Prev 2015 Aug 26;24(8):1222-8. Epub 2015 May 26.

Department of Pediatrics, The University of Chicago, Chicago, Illinois. The University of Chicago Comprehensive Cancer Center, The University of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1158/1055-9965.EPI-15-0275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526396PMC
August 2015

Establishing a translational genomics infrastructure in pediatric cancer: the GREAT KIDS experience.

Per Med 2015 Jun;12(3):221-229

Department of Pediatrics, The University of Chicago, 5801 S Ellis Ave, Chicago, IL 60637, USA.

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http://dx.doi.org/10.2217/pme.14.90DOI Listing
June 2015

The APC tumor suppressor is required for epithelial cell polarization and three-dimensional morphogenesis.

Biochim Biophys Acta 2015 Mar 8;1853(3):711-23. Epub 2015 Jan 8.

Department of Biochemistry and Molecular Biology, Indiana University School of Medicine - South Bend, South Bend, IN 46617, USA; Department of Biological Sciences and Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2014.12.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327896PMC
March 2015

Systematic computation with functional gene-sets among leukemic and hematopoietic stem cells reveals a favorable prognostic signature for acute myeloid leukemia.

BMC Bioinformatics 2015 Mar 24;16:97. Epub 2015 Mar 24.

Department of Pediatrics, and Comer Children's Hospital, Section of Hematology/Oncology, The University of Chicago, 900 East 57th Street, KCBD Room 5121, Chicago, Illinois, 60637, USA.

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http://dx.doi.org/10.1186/s12859-015-0510-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376348PMC
March 2015

Radiation-induced apoptosis varies among individuals and is modified by sex and age.

Int J Radiat Biol 2014 Oct 25;90(10):903-8. Epub 2014 Jun 25.

Department of Pediatrics, The University of Chicago , Chicago, Illinois , USA.

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http://dx.doi.org/10.3109/09553002.2014.925603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222525PMC
October 2014

Evolving risk of therapy-related acute myeloid leukemia following cancer chemotherapy among adults in the United States, 1975-2008.

Blood 2013 Apr 14;121(15):2996-3004. Epub 2013 Feb 14.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1182/blood-2012-08-448068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624944PMC
April 2013

Proposal for the clinical detection and management of patients and their family members with familial myelodysplastic syndrome/acute leukemia predisposition syndromes.

Leuk Lymphoma 2013 Jan 9;54(1):28-35. Epub 2012 Jul 9.

Section of Hematology/Oncology, Department of Medicine and Center for Clinical Cancer Genetics, The University of Chicago, Chicago, IL, USA.

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http://www.tandfonline.com/doi/full/10.3109/10428194.2012.70
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http://dx.doi.org/10.3109/10428194.2012.701738DOI Listing
January 2013

Tumor necrosis factor inhibitors and cancer in juvenile idiopathic arthritis: disentangling the web.

Arthritis Rheum 2012 Apr 10;64(4):966-9. Epub 2012 Feb 10.

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http://dx.doi.org/10.1002/art.34349DOI Listing
April 2012

Heritability of hematologic malignancies: from pedigrees to genomics.

Hematol Oncol Clin North Am 2010 Oct;24(5):939-72

Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.hoc.2010.06.001DOI Listing
October 2010

Anti-tumor necrosis factor therapy and cancer risk in patients with autoimmune disorders.

Arthritis Care Res (Hoboken) 2010 Jul;62(7):1024-8

University of Chicago, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1002/acr.20228DOI Listing
July 2010

Translating genetic questions into clinical answers in acute myeloid leukemia.

Leuk Res 2009 Nov 23;33(11):1448-9. Epub 2009 Jul 23.

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http://dx.doi.org/10.1016/j.leukres.2009.06.018DOI Listing
November 2009

MDM2 SNP309 and TP53 Arg72Pro interact to alter therapy-related acute myeloid leukemia susceptibility.

Blood 2008 Aug 21;112(3):741-9. Epub 2008 Apr 21.

Department of Medicine, University of Chicago Cancer Research Center, University of Chicago, IL 60637, USA.

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http://dx.doi.org/10.1182/blood-2007-11-126508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481552PMC
August 2008

Genetic predictors of long-term toxicities after radiation therapy for breast cancer.

Int J Cancer 2008 Mar;122(6):1333-9

Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.

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http://dx.doi.org/10.1002/ijc.23138DOI Listing
March 2008

The broken genome: genetic and pharmacologic approaches to breaking DNA.

Ann Med 2007 ;39(3):208-18

Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1080/08035250601167136DOI Listing
July 2007

The TP53 mutational spectrum and frequency of CHEK2*1100delC in Li-Fraumeni-like kindreds.

Fam Cancer 2005 ;4(2):177-81

Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

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http://link.springer.com/10.1007/s10689-004-1946-5
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http://dx.doi.org/10.1007/s10689-004-1946-5DOI Listing
September 2005

The genetics of familial lymphomas.

Curr Oncol Rep 2004 Sep;6(5):380-7

Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

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http://dx.doi.org/10.1007/s11912-004-0064-8DOI Listing
September 2004

MDM2 and prognosis.

Mol Cancer Res 2004 Jan;2(1):1-8

Division of Molecular Pathology, Department of Pathology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

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January 2004

Differential recruitment of caspase 8 to cFlip confers sensitivity or resistance to Fas-mediated apoptosis in a subset of familial lymphoma patients.

Leuk Res 2003 Sep;27(9):841-51

Hospital for Special Surgery, Weill Medical College of Cornell University, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/s0145-2126(03)00018-3DOI Listing
September 2003

Pediatric AML: past, present, and future.

Cancer Invest 2002 ;20(7-8):1117

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http://dx.doi.org/10.1081/cnv-120005931DOI Listing
December 2002