Publications by authors named "Ken C Pang"

45Publications

Proteomic analysis of extracellular vesicles reveals an immunogenic cargo in rheumatoid arthritis synovial fluid.

Clin Transl Immunology 2020 7;9(11):e1185. Epub 2020 Nov 7.

The Walter and Eliza Hall Institute of Medical Research Parkville VIC Australia.

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http://dx.doi.org/10.1002/cti2.1185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648259PMC
November 2020

"No One Stays Just on Blockers Forever": Clinicians' Divergent Views and Practices Regarding Puberty Suppression for Nonbinary Young People.

J Adolesc Health 2020 Oct 26. Epub 2020 Oct 26.

Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1016/j.jadohealth.2020.09.028DOI Listing
October 2020

Identity, well-being and autonomy in ongoing puberty suppression for non-binary adults: a response to the commentaries.

J Med Ethics 2020 Nov 21;46(11):761-762. Epub 2020 Oct 21.

Department of Adolescent Medicine, The Royal Children's Hospital Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1136/medethics-2020-106942DOI Listing
November 2020

Forever young? The ethics of ongoing puberty suppression for non-binary adults.

J Med Ethics 2020 Nov 24;46(11):743-752. Epub 2020 Jul 24.

Department of Adolescent Medicine, The Royal Children's Hospital Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1136/medethics-2019-106012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7656150PMC
November 2020

Circulating Small Noncoding RNA Biomarkers of Response to Triple Disease-modifying Antirheumatic Drug Therapy in White Women With Early Rheumatoid Arthritis.

J Rheumatol 2020 Jun 15. Epub 2020 Jun 15.

This work was supported by the Reid Family Trust (IPW) and the Royal Children's Hospital Foundation (KCP). A.D. Foers, PhD, A.L. Garnham, PhD, The Walter and Eliza Hall Institute of Medical Research, and Department of Medical Biology, University of Melbourne, Parkville; G.K. Smyth, PhD, The Walter and Eliza Hall Institute of Medical Research, and School of Mathematics & Statistics, University of Melbourne, Parkville; S.M. Proudman, MB BS, Rheumatology Unit, Royal Adelaide Hospital, and Discipline of Medicine, University of Adelaide, Adelaide; L.Cheng, PhD, A.F. Hill, PhD, Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Bundoora; K.C. Pang, MB BS, PhD, Departments of Paediatrics, Psychiatry and Adolescent Medicine, University of Melbourne, and Murdoch Children's Research Institute, Parkville; I.P. Wicks, MB BS, PhD, The Walter and Eliza Hall Institute of Medical Research, and Department of Rheumatology, Royal Melbourne Hospital, Parkville, Australia. K.C. Pang and I.P. Wicks contributed equally. SMP reports grants from Actelion Pharmaceuticals and Melrose, outside the submitted work. Address correspondence to Dr. I.P. Wicks, The Walter & Eliza Hall Institute, Parkville, VIC 3052, Autralia. Email: Dr. K.C. Pang, Murdoch Children's Research Institute, Parkville, VIC 3052, Australia. Email: Accepted for publication June 4, 2020.

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http://dx.doi.org/10.3899/jrheum.191012DOI Listing
June 2020

Non-Binary and Binary Gender Identity in Australian Trans and Gender Diverse Individuals.

Arch Sex Behav 2020 10 13;49(7):2673-2681. Epub 2020 Apr 13.

Murdoch Children's Research Institute and University of Melbourne (Department of Paediatrics), Royal Children's Hospital, Parkville, VIC, Australia.

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http://dx.doi.org/10.1007/s10508-020-01689-9DOI Listing
October 2020

Fertility Counseling for Transgender Adolescents: A Review.

J Adolesc Health 2020 Jun 27;66(6):658-665. Epub 2020 Feb 27.

Royal Children's Hospital, Parkville, Victoria, Australia; Murdoch Children's Research Institute, Parkville, Victoria, Australia; Department of Paediatrics, University of Melbourne, Parkville, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jadohealth.2020.01.007DOI Listing
June 2020

Youths with a non-binary gender identity: a review of their sociodemographic and clinical profile.

Lancet Child Adolesc Health 2020 04 21;4(4):322-330. Epub 2020 Jan 21.

Department of Paediatrics, University of Melbourne, Parkville, VIC, Australia; Murdoch Children's Research Institute, Parkville, VIC, Australia; Royal Children's Hospital, Melbourne, VIC, Australia; Inflammation Division, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia. Electronic address:

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http://dx.doi.org/10.1016/S2352-4642(19)30403-1DOI Listing
April 2020

Gender dysphoria: puberty blockers and loss of bone mineral density.

BMJ 2019 12 4;367:l6471. Epub 2019 Dec 4.

Murdoch Children's Research Institute, Parkville, VIC 3052, Australia.

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http://dx.doi.org/10.1136/bmj.l6471DOI Listing
December 2019

Prevalence of Autism Spectrum Disorder and Attention-Deficit Hyperactivity Disorder Amongst Individuals with Gender Dysphoria: A Systematic Review.

J Autism Dev Disord 2020 Mar;50(3):695-706

Department of Medicine (Austin Health), The University of Melbourne, Studley Road, Heidelberg, VIC, Australia.

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http://dx.doi.org/10.1007/s10803-019-04298-1DOI Listing
March 2020

SIDT2 RNA Transporter Promotes Lung and Gastrointestinal Tumor Development.

iScience 2019 Oct 10;20:14-24. Epub 2019 Sep 10.

The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; Murdoch Children's Research Institute, Parkville, VIC, Australia; Department of Paediatrics, University of Melbourne, Parkville, VIC, Australia; Department of Psychiatry, University of Melbourne, Parkville, VIC, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2019.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817685PMC
October 2019

Should Parental Refusal of Puberty-Blocking Treatment be Overridden? The Role of the Harm Principle.

Am J Bioeth 2019 02;19(2):69-72

Murdoch Children's Research Institute, Royal Children's Hospital, University of Melbourne, and The Walter and Eliza Hall Institute of Medical Research.

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http://dx.doi.org/10.1080/15265161.2018.1557283DOI Listing
February 2019

Everyone agrees transgender children require more science.

Med J Aust 2019 08 17;211(3):142-142.e1. Epub 2019 Jun 17.

Royal Children's Hospital, Melbourne, VIC.

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http://dx.doi.org/10.5694/mja2.50237DOI Listing
August 2019

Facial Feminization Surgery: Privacy, Personal Identity, Compensatory Justice, and Resource Allocation.

Am J Bioeth 2018 12;18(12):12-15

c Murdoch Children's Research Institute, University of Melbourne, and Institute of Medical Research.

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http://dx.doi.org/10.1080/15265161.2018.1531168DOI Listing
December 2018

SIDT1 Localizes to Endolysosomes and Mediates Double-Stranded RNA Transport into the Cytoplasm.

J Immunol 2019 06 6;202(12):3483-3492. Epub 2019 May 6.

Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia;

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1801369
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http://dx.doi.org/10.4049/jimmunol.1801369DOI Listing
June 2019

Generation of four iPSC lines from peripheral blood mononuclear cells (PBMCs) of an attention deficit hyperactivity disorder (ADHD) individual and a healthy sibling in an Australia-Caucasian family.

Stem Cell Res 2019 01 19;34:101353. Epub 2018 Dec 19.

Monash Institute of Cognitive and Clinical Neurosciences and School of Psychological Sciences, Monash University, Wellington Road, Clayton, Victoria, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S18735061183028
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http://dx.doi.org/10.1016/j.scr.2018.11.014DOI Listing
January 2019

Molecular Karyotyping in Children and Adolescents with Gender Dysphoria.

Transgend Health 2018 1;3(1):147-153. Epub 2018 Aug 1.

Department of Adolescent Medicine, Royal Children's Hospital, Parkville, Australia.

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http://dx.doi.org/10.1089/trgh.2017.0051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083207PMC
August 2018

Enrichment of extracellular vesicles from human synovial fluid using size exclusion chromatography.

J Extracell Vesicles 2018 26;7(1):1490145. Epub 2018 Jun 26.

Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1080/20013078.2018.1490145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022248PMC
June 2018

Australian standards of care and treatment guidelines for transgender and gender diverse children and adolescents.

Med J Aust 2018 08 18;209(3):132-136. Epub 2018 Jun 18.

Royal Children's Hospital Melbourne, Melbourne, VIC.

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August 2018

Detection and Quantification of MAVS Aggregation via Confocal Microscopy.

Methods Mol Biol 2018 ;1714:237-247

Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC, 3052, Australia.

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http://dx.doi.org/10.1007/978-1-4939-7519-8_16DOI Listing
July 2018

SIDT2 Transports Extracellular dsRNA into the Cytoplasm for Innate Immune Recognition.

Immunity 2017 09 12;47(3):498-509.e6. Epub 2017 Sep 12.

The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; Murdoch Childrens Research Institute, Parkville, VIC, Australia; Department of Paediatrics, University of Melbourne, Parkville, VIC, Australia; Department of Psychiatry, University of Melbourne, Parkville, VIC, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679266PMC
September 2017

Typical Pubertal Timing in an Australian Population of Girls and Boys with Autism Spectrum Disorder.

J Autism Dev Disord 2017 Dec;47(12):3983-3993

Department of Paediatrics, University of Melbourne, Parkville, Australia.

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http://link.springer.com/10.1007/s10803-017-3281-3
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http://dx.doi.org/10.1007/s10803-017-3281-3DOI Listing
December 2017

Brief Report: Sexual Attraction and Relationships in Adolescents with Autism.

J Autism Dev Disord 2017 06;47(6):1910-1916

Department of Paediatrics, University of Melbourne, Parkville, Australia.

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http://dx.doi.org/10.1007/s10803-017-3092-6DOI Listing
June 2017

Review: Extracellular Vesicles in Joint Inflammation.

Arthritis Rheumatol 2017 07 5;69(7):1350-1362. Epub 2017 Jun 5.

Murdoch Childrens Research Institute and The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1002/art.40076DOI Listing
July 2017

Intercellular communication for innate immunity.

Mol Immunol 2017 06 18;86:16-22. Epub 2016 Oct 18.

Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia.

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http://dx.doi.org/10.1016/j.molimm.2016.10.002DOI Listing
June 2017

Increasing viral dose causes a reversal in CD8+ T cell immunodominance during primary influenza infection due to differences in antigen presentation, T cell avidity, and precursor numbers.

J Immunol 2013 Jan 10;190(1):36-47. Epub 2012 Dec 10.

Infection and Inflammation Research Centre, School of Medical Sciences, University of New South Wales, Sydney, New South Wales 2052, Australia.

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http://dx.doi.org/10.4049/jimmunol.1200089DOI Listing
January 2013

CD8(+) T cells that produce interleukin-17 regulate myeloid-derived suppressor cells and are associated with survival time of patients with gastric cancer.

Gastroenterology 2012 Oct 15;143(4):951-62.e8. Epub 2012 Jun 15.

Department of Clinical Microbiology and Immunology, College of Medical Laboratory Science, Third Military Medical University, Chongqing, China.

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http://dx.doi.org/10.1053/j.gastro.2012.06.010DOI Listing
October 2012

Direct antigen presentation by DC shapes the functional CD8(+) T-cell repertoire against the nuclear self-antigen La-SSB.

Eur J Immunol 2010 Feb;40(2):330-8

Department of Microbiology and Immunology, University of Melbourne, Victoria, Australia.

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http://doi.wiley.com/10.1002/eji.200939522
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http://dx.doi.org/10.1002/eji.200939522DOI Listing
February 2010

Non-coding RNAs: regulators of disease.

J Pathol 2010 Jan;220(2):126-39

Institute for Molecular Bioscience, University of Queensland, Brisbane QLD 4072, Australia.

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http://doi.wiley.com/10.1002/path.2638
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http://dx.doi.org/10.1002/path.2638DOI Listing
January 2010

Genome-wide identification of long noncoding RNAs in CD8+ T cells.

J Immunol 2009 Jun;182(12):7738-48

Australian Research Council Special Research Centre for Functional and Applied Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia.

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http://dx.doi.org/10.4049/jimmunol.0900603DOI Listing
June 2009

Differentiating protein-coding and noncoding RNA: challenges and ambiguities.

PLoS Comput Biol 2008 Nov 28;4(11):e1000176. Epub 2008 Nov 28.

ARC Special Research Centre for Functional and Applied Genomics, Institute for Molecular Bioscience, University of Queensland, St Lucia, Australia.

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http://dx.doi.org/10.1371/journal.pcbi.1000176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518207PMC
November 2008

NRED: a database of long noncoding RNA expression.

Nucleic Acids Res 2009 Jan 1;37(Database issue):D122-6. Epub 2008 Oct 1.

ARC Special Research Centre for Functional and Applied Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland 4072, Australia.

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http://nar.oxfordjournals.org/content/early/2008/10/01/nar.g
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http://nar.oxfordjournals.org/lookup/doi/10.1093/nar/gkn617
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http://dx.doi.org/10.1093/nar/gkn617DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686506PMC
January 2009

Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation.

Genome Res 2008 Sep 18;18(9):1433-45. Epub 2008 Jun 18.

ARC Special Research Centre for Functional and Applied Genomics, Institute for Molecular Bioscience, University of Queensland, St Lucia QLD 4072, Australia.

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http://dx.doi.org/10.1101/gr.078378.108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527704PMC
September 2008

RNAdb 2.0--an expanded database of mammalian non-coding RNAs.

Nucleic Acids Res 2007 Jan 1;35(Database issue):D178-82. Epub 2006 Dec 1.

ARC Special Research Centre for Functional and Applied Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland 4072, Australia.

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http://dx.doi.org/10.1093/nar/gkl926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751534PMC
January 2007

Immunoproteasome subunit deficiencies impact differentially on two immunodominant influenza virus-specific CD8+ T cell responses.

J Immunol 2006 Dec;177(11):7680-8

T Cell Laboratory, Melbourne Centre for Clinical Sciences, Ludwig Institute for Cancer Research, Austin Health, Heidelberg, Victoria 3084, Australia.

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http://dx.doi.org/10.4049/jimmunol.177.11.7680DOI Listing
December 2006

The abundance of short proteins in the mammalian proteome.

PLoS Genet 2006 Apr 28;2(4):e52. Epub 2006 Apr 28.

Genome Exploration Research Group (Genome Network Project Core Group), RIKEN Genomic Sciences Center, RIKEN Yokohama Institute, Yokohama, Japan.

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http://dx.plos.org/10.1371/journal.pgen.0020052
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http://dx.doi.org/10.1371/journal.pgen.0020052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1449894PMC
April 2006

Clusters of internally primed transcripts reveal novel long noncoding RNAs.

PLoS Genet 2006 Apr 28;2(4):e37. Epub 2006 Apr 28.

Mouse Genome Informatics Consortium, The Jackson Laboratory, Bar Harbor, Maine, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.0020037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1449886PMC
April 2006

Dynamic quantification of MHC class I-peptide presentation to CD8+ T cells via intracellular cytokine staining.

J Immunol Methods 2006 Apr 20;311(1-2):12-8. Epub 2006 Feb 20.

T cell Laboratory, Ludwig Institute for Cancer Research, Melbourne Branch, Austin Health, Heidelberg, VIC, 3084, Australia.

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http://dx.doi.org/10.1016/j.jim.2006.01.008DOI Listing
April 2006

Experimental validation of the regulated expression of large numbers of non-coding RNAs from the mouse genome.

Genome Res 2006 Jan 12;16(1):11-9. Epub 2005 Dec 12.

ARC Special Research Centre for Functional and Applied Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane QLD 4072, Australia.

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http://dx.doi.org/10.1101/gr.4200206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356124PMC
January 2006

Rapid evolution of noncoding RNAs: lack of conservation does not mean lack of function.

Trends Genet 2006 Jan 10;22(1):1-5. Epub 2005 Nov 10.

ARC Special Research Centre for Functional and Applied Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane QLD 4072, Australia.

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http://dx.doi.org/10.1016/j.tig.2005.10.003DOI Listing
January 2006

RNAdb--a comprehensive mammalian noncoding RNA database.

Nucleic Acids Res 2005 Jan;33(Database issue):D125-30

ARC Special Research Centre for Functional and Applied Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland 4072, Australia.

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http://dx.doi.org/10.1093/nar/gki089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC540043PMC
January 2005