Kelly L Brown

Kelly L Brown

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Kelly L Brown

Kelly L Brown

Publications by authors named "Kelly L Brown"

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Hyaluronan primes the oxidative burst in human neutrophils.

J Leukoc Biol 2020 May 18. Epub 2020 May 18.

BC Children's Hospital Research Institute, The University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1002/JLB.3MA0220-216RRDOI Listing
May 2020

Anti-neutrophil cytoplasmic antibodies (ANCA): Antigen interactions and downstream effects.

J Leukoc Biol 2020 May 18. Epub 2020 May 18.

Department of Pediatrics, Division of Rheumatology, The University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1002/JLB.3VMR0220-438RRDOI Listing
May 2020

Methods for type I interferon detection and their relevance for clinical utility and improved understanding of rheumatic diseases.

Clin Exp Rheumatol 2019 Nov-Dec;37(6):1077-1083. Epub 2019 Mar 25.

Department of Paediatrics, Division of Rheumatology, The University of British Columbia, and BC Children's Hospital Research Institute, Vancouver, Canada.

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December 2019

Complexity in unclassified auto-inflammatory disease: a case report illustrating the potential for disease arising from the allelic burden of multiple variants.

Pediatr Rheumatol Online J 2019 Oct 28;17(1):70. Epub 2019 Oct 28.

Department of Pediatrics, The University of British Columbia Faculty of Medicine, BC Children's Hospital, 4480 Oak Street, Vancouver, BC, V6H 3V4, Canada.

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http://dx.doi.org/10.1186/s12969-019-0374-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819641PMC
October 2019

Comparable type I interferon score determination from PAXgene and Tempus whole blood RNA collection and isolation systems.

BMC Res Notes 2019 Aug 15;12(1):511. Epub 2019 Aug 15.

Division of Rheumatology, Department of Pediatrics, Faculty of Medicine, The University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1186/s13104-019-4562-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694656PMC
August 2019

The Value of Creativity for Enhancing Translational Ecologies, Insights, and Discoveries.

Front Psychol 2019 9;10:951. Epub 2019 Jul 9.

Discovery Lead Nutrition and Health Science, Corporate R&D, Lesaffre International, Lille, France.

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http://dx.doi.org/10.3389/fpsyg.2019.00951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637314PMC
July 2019

Periodic fever syndromes: beyond the single gene paradigm.

Pediatr Rheumatol Online J 2019 May 14;17(1):22. Epub 2019 May 14.

Division of Rheumatology, Department of Pediatrics, University of British Columbia, Vancouver, Canada.

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https://ped-rheum.biomedcentral.com/articles/10.1186/s12969-
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http://dx.doi.org/10.1186/s12969-019-0324-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515597PMC
May 2019

Emergency management communication on university Web sites: A 7-year study.

J Emerg Manag 2016 Jul-Aug;14(4):259-68

Department of Criminal Justice and Homeland Security, Indiana University Kokomo, Kokomo, Indiana.

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http://dx.doi.org/10.5055/jem.2016.0291DOI Listing
September 2018

Elevated Mitochondrial Reactive Oxygen Species and Cellular Redox Imbalance in Human NADPH-Oxidase-Deficient Phagocytes.

Front Immunol 2017 21;8:1828. Epub 2017 Dec 21.

The Phagocyte Research Group, Department of Rheumatology and Inflammation Research, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.3389/fimmu.2017.01828DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744066PMC
December 2017

Clinical practice variation and need for pediatric-specific treatment guidelines among rheumatologists caring for children with ANCA-associated vasculitis: an international clinician survey.

Pediatr Rheumatol Online J 2017 Aug 7;15(1):61. Epub 2017 Aug 7.

Clinical Professor, Division of Rheumatology, Department of Pediatrics, University of British Columbia, BC Children's Hospital, Room K4-119 4480 Oak Street Vancouver, Vancouver, BC, V6H 3V4, Canada.

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http://dx.doi.org/10.1186/s12969-017-0191-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545848PMC
August 2017

The where, when, how, and why of hyaluronan binding by immune cells.

Front Immunol 2015 14;6:150. Epub 2015 Apr 14.

Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia , Vancouver, BC , Canada.

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http://dx.doi.org/10.3389/fimmu.2015.00150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396519PMC
April 2015

Innate defense regulator peptide 1018 protects against perinatal brain injury.

Ann Neurol 2014 Mar 7;75(3):395-410. Epub 2014 Mar 7.

Institute of Neuroscience and Physiology, Department of Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1002/ana.24087DOI Listing
March 2014

Differential use of chondroitin sulfate to regulate hyaluronan binding by receptor CD44 in Inflammatory and Interleukin 4-activated Macrophages.

J Biol Chem 2011 Jun 6;286(22):19179-90. Epub 2011 Apr 6.

Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M110.200790
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http://dx.doi.org/10.1074/jbc.M110.200790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103297PMC
June 2011

Multiplex short tandem repeat amplification of low template DNA samples with the addition of proofreading enzymes.

J Forensic Sci 2011 May 6;56(3):726-32. Epub 2011 Apr 6.

Department of Forensic Science and Biology, Virginia Commonwealth University, 1000 West Cary Street, PO Box 842012, Richmond, VA 23284, USA.

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http://doi.wiley.com/10.1111/j.1556-4029.2011.01727.x
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http://dx.doi.org/10.1111/j.1556-4029.2011.01727.xDOI Listing
May 2011

Intracellular generation of superoxide by the phagocyte NADPH oxidase: how, where, and what for?

Free Radic Biol Med 2010 Dec 24;49(12):1834-45. Epub 2010 Sep 24.

Department of Rheumatology and Inflammation Research, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1016/j.freeradbiomed.2010.09.016DOI Listing
December 2010

Profile of blood cells and inflammatory mediators in periodic fever, aphthous stomatitis, pharyngitis and adenitis (PFAPA) syndrome.

BMC Pediatr 2010 Sep 6;10:65. Epub 2010 Sep 6.

Department of Rheumatology and Inflammation Research, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1186/1471-2431-10-65DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944328PMC
September 2010

Divergent effects on phagocytosis by macrophage-derived oxygen radicals.

J Innate Immun 2009 14;1(6):592-8. Epub 2009 Aug 14.

Department of Rheumatology and Inflammation Research, University of Gothenburg, Gothenburg, Sweden.

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https://www.karger.com/Article/FullText/235583
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http://dx.doi.org/10.1159/000235583DOI Listing
May 2010

G-protein-coupled receptor independent, immunomodulatory properties of chemokine CXCL9.

Cell Immunol 2010 3;261(2):105-13. Epub 2009 Dec 3.

Centre for Microbial Diseases and Immunity Research, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1016/j.cellimm.2009.11.007DOI Listing
March 2010

Treating neonatal brain injury - promise and inherent research challenges.

Recent Pat Inflamm Allergy Drug Discov 2010 Jan;4(1):16-24

Perinatal Center, The Queen Silvia Children's Hospital, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.2174/187221310789895586DOI Listing
January 2010

Robust TLR4-induced gene expression patterns are not an accurate indicator of human immunity.

J Transl Med 2010 Jan 27;8. Epub 2010 Jan 27.

Centre for Microbial Diseases and Immunity Research, Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, V6T 1Z3, Canada.

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http://translational-medicine.biomedcentral.com/articles/10.
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http://dx.doi.org/10.1186/1479-5876-8-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843650PMC
January 2010

Manual annotation and analysis of the defensin gene cluster in the C57BL/6J mouse reference genome.

BMC Genomics 2009 Dec 15;10:606. Epub 2009 Dec 15.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.

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http://dx.doi.org/10.1186/1471-2164-10-606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807441PMC
December 2009

The host defense peptide LL-37 selectively permeabilizes apoptotic leukocytes.

Antimicrob Agents Chemother 2009 Mar 15;53(3):1027-38. Epub 2008 Dec 15.

Department of Rheumatology and Inflammation Research, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1128/AAC.01310-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650579PMC
March 2009

Galectin-3 functions as an opsonin and enhances the macrophage clearance of apoptotic neutrophils.

Glycobiology 2009 Jan 10;19(1):16-20. Epub 2008 Oct 10.

Department of Rheumatology and Inflammation Research, University of Gothenburg, Sweden.

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https://academic.oup.com/glycob/article-lookup/doi/10.1093/g
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http://dx.doi.org/10.1093/glycob/cwn104DOI Listing
January 2009

ROS-deficient monocytes have aberrant gene expression that correlates with inflammatory disorders of chronic granulomatous disease.

Clin Immunol 2008 Oct 26;129(1):90-102. Epub 2008 Jul 26.

Centre for Microbial Disease Research, Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1016/j.clim.2008.06.005DOI Listing
October 2008

Complexities of targeting innate immunity to treat infection.

Trends Immunol 2007 Jun 30;28(6):260-6. Epub 2007 Apr 30.

Centre for Microbial Diseases and Immunity Research, University of British Columbia, Vancouver, British Columbia, V6T 1Z4, Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S147149060700100
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http://dx.doi.org/10.1016/j.it.2007.04.005DOI Listing
June 2007

Enhanced inflammatory responses of chronic granulomatous disease leukocytes involve ROS-independent activation of NF-kappa B.

Eur J Immunol 2007 Apr;37(4):1087-96

Department of Pediatrics, University of British Columbia, Child and Family Research Institute, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1002/eji.200636651DOI Listing
April 2007

Host defence peptides from invertebrates--emerging antimicrobial strategies.

Immunobiology 2006 17;211(4):315-22. Epub 2006 Apr 17.

Department of Microbiology and Immunology, University of British Columbia, 2259 Lower Mall, Vancouver, BC, Canada V6T 1Z4.

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http://dx.doi.org/10.1016/j.imbio.2005.10.017DOI Listing
October 2006

Cationic host defense (antimicrobial) peptides.

Curr Opin Immunol 2006 Feb 6;18(1):24-30. Epub 2005 Dec 6.

Centre for Microbial Diseases and Immunity Research, University of British Columbia, Vancouver, British Columbia, V6T 1Z4, Canada.

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http://dx.doi.org/10.1016/j.coi.2005.11.004DOI Listing
February 2006

Modulation of the TLR-mediated inflammatory response by the endogenous human host defense peptide LL-37.

J Immunol 2006 Feb;176(4):2455-64

Centre for Microbial Diseases and Immunity Research, Department of Microbiology and Immunology, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.4049/jimmunol.176.4.2455DOI Listing
February 2006

Expression of N-acetylglucosamine 6-O-sulfotransferases (GlcNAc6STs)-1 and -4 in human monocytes: GlcNAc6ST-1 is implicated in the generation of the 6-sulfo N-acetyllactosamine/Lewis x epitope on CD44 and is induced by TNF-alpha.

Glycobiology 2005 Jul 23;15(7):7C-13C. Epub 2005 Feb 23.

Department of Microbiology and Immunology, University of British Columbia, 300-6174 University Boulevard, Vancouver, British Columbia, Canada V6T 1Z3.

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http://dx.doi.org/10.1093/glycob/cwi050DOI Listing
July 2005

Regulation of hyaluronan binding by F-actin and colocalization of CD44 and phosphorylated ezrin/radixin/moesin (ERM) proteins in myeloid cells.

Exp Cell Res 2005 Feb;303(2):400-14

Department of Microbiology and Immunology, University of British Columbia, #300-6174 University Boulevard, Vancouver, B.C., Canada, V6T 1Z3.

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http://dx.doi.org/10.1016/j.yexcr.2004.10.002DOI Listing
February 2005