Keith R Johnson

Keith R Johnson

UNVERIFIED PROFILE

Are you Keith R Johnson?   Register this Author

Register author
Keith R Johnson

Keith R Johnson

Publications by authors named "Keith R Johnson"

Are you Keith R Johnson?   Register this Author

41Publications

-Reads

Palmitoylation of Desmoglein 2 Is a Regulator of Assembly Dynamics and Protein Turnover.

J Biol Chem 2016 Nov 4;291(48):24857-24865. Epub 2016 Oct 4.

From the Department of Oral Biology, College of Dentistry, University of Nebraska Medical Center, Lincoln, Nebraska 68583,

View Article
November 2016

The carboxyl tail of connexin32 regulates gap junction assembly in human prostate and pancreatic cancer cells.

J Biol Chem 2015 Feb 29;290(8):4647-62. Epub 2014 Dec 29.

From the Department of Biochemistry and Molecular Biology, Department of Oral Biology, Eppley Institute for Research in Cancer and Allied Diseases, Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska 68198

View Article
February 2015

Palmitoylation of plakophilin is required for desmosome assembly.

J Cell Sci 2014 Sep 7;127(Pt 17):3782-93. Epub 2014 Jul 7.

The University of Nebraska Medical Center, College of Dentistry, Department of Oral Biology, Lincoln, NE 68583, USA

View Article
September 2014

Interactions between MUC1 and p120 catenin regulate dynamic features of cell adhesion, motility, and metastasis.

Cancer Res 2014 Mar 26;74(5):1609-20. Epub 2013 Dec 26.

Authors' Affiliations: Eppley Institute for Research in Cancer and Allied Disease; Department of Oral Biology, University of Nebraska Medical Center, Omaha, Nebraska; Department of Gynecologic Oncology and Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas; and Department of Translational Oncology, Genentech, Inc., 1 DNA Way, South San Francisco, California.

View Article
March 2014

Phosphorylation on Ser-279 and Ser-282 of connexin43 regulates endocytosis and gap junction assembly in pancreatic cancer cells.

Mol Biol Cell 2013 Mar 30;24(6):715-33. Epub 2013 Jan 30.

Department of Biochemistry and Molecular Biology, Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE 68198, USA.

View Article
March 2013

Differential expression of metabolic genes in tumor and stromal components of primary and metastatic loci in pancreatic adenocarcinoma.

PLoS One 2012 7;7(3):e32996. Epub 2012 Mar 7.

The Eppley Institute for Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, United States of America.

View Article
August 2012

MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer.

Proc Natl Acad Sci U S A 2012 Aug 6;109(34):13787-92. Epub 2012 Aug 6.

Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE 68198, USA.

View Article
August 2012

Desmosome dynamics in migrating epithelial cells requires the actin cytoskeleton.

Exp Cell Res 2011 Dec 16;317(20):2814-22. Epub 2011 Sep 16.

The University of Nebraska Medical Center College of Dentistry, Lincoln, NE 68583, USA.

View Article
December 2011

Regulation of Aerobic Glycolysis by microRNAs in Cancer.

Mol Cell Pharmacol 2011 ;3(3):125-134

Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska.

View Article
January 2011

Assembly of connexin43 into gap junctions is regulated differentially by E-cadherin and N-cadherin in rat liver epithelial cells.

Mol Biol Cell 2010 Dec 29;21(23):4089-107. Epub 2010 Sep 29.

Department of Biochemistry and Molecular Biology, Eppley Institute for Research in Cancer and Allied Diseases, Eppley Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198, USA.

View Article
December 2010

E-cadherin differentially regulates the assembly of Connexin43 and Connexin32 into gap junctions in human squamous carcinoma cells.

J Biol Chem 2010 Apr 10;285(14):10761-76. Epub 2010 Jan 10.

Department of Biochemistry and Molecular Biology, Eppley Institute for Research in Cancer and Allied Diseases, Eppley Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska 68198, USA.

View Article
April 2010

Expression artifact with retroviral vectors based on pBMN.

Anal Biochem 2009 Dec 12;395(1):49-53. Epub 2009 Jul 12.

Department of Oral Biology, University of Nebraska Medical Center, Omaha, 68198, USA.

View Article
December 2009

TGF-beta induces formation of F-actin cores and matrix degradation in human breast cancer cells via distinct signaling pathways.

Exp Cell Res 2008 Nov 26;314(19):3478-93. Epub 2008 Sep 26.

Department of Biochemistry, University of Nebraska Medical Center, Omaha, NE 68198-7696, USA.

View Article
November 2008

E-cadherin/catenin complexes are formed cotranslationally in the endoplasmic reticulum/Golgi compartments.

Cell Commun Adhes 2008 Nov;15(4):365-78

Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska 68198-7696, USA.

View Article
November 2008

Generation and characterization of monoclonal antibodies against the proregion of human desmoglein-2.

Hybridoma (Larchmt) 2008 Aug;27(4):249-58

University of Nebraska Medical Center, Department of Genetics, Cell Biology and Anatomy, Omaha, Nebraska 68198-7696, USA.

View Article
August 2008

Cadherin switching.

J Cell Sci 2008 Mar;121(Pt 6):727-35

University of Nebraska Medical Center, Department of Oral Biology and Eppley Cancer Center, Omaha, NE 68198-7696, USA.

View Article
March 2008

Collagen I-mediated up-regulation of N-cadherin requires cooperative signals from integrins and discoidin domain receptor 1.

J Cell Biol 2008 Mar;180(6):1277-89

Department of Oral Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA.

View Article
March 2008

Collagen I promotes epithelial-to-mesenchymal transition in lung cancer cells via transforming growth factor-beta signaling.

Am J Respir Cell Mol Biol 2008 Jan 2;38(1):95-104. Epub 2007 Aug 2.

Department of Oral Biology, Eppley Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska, USA.

View Article
January 2008

The regulatory or phosphorylation domain of p120 catenin controls E-cadherin dynamics at the plasma membrane.

Exp Cell Res 2008 Jan 31;314(1):52-67. Epub 2007 Jul 31.

Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska 68198-7696, USA.

View Article
January 2008

ADH-1 suppresses N-cadherin-dependent pancreatic cancer progression.

Int J Cancer 2008 Jan;122(1):71-7

Department of Oral Biology, University of Nebraska Medical Center, Omaha, NE 68198-7696, USA.

View Article
January 2008

Evidence that the V832M E-cadherin germ-line missense mutation does not influence the affinity of alpha -catenin for the cadherin/catenin complex.

Cell Commun Adhes 2007 Mar-Jun;14(2-3):45-55

University of Nebraska Medical Center, Department of Pathology and Microbiology, Omaha, Nebraska, USA.

View Article
September 2007

NHERF links the N-cadherin/catenin complex to the platelet-derived growth factor receptor to modulate the actin cytoskeleton and regulate cell motility.

Mol Biol Cell 2007 Apr 17;18(4):1220-32. Epub 2007 Jan 17.

Department of Biochemistry and Molecular Biology, Eppley Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198-7696, USA.

View Article
April 2007

Expression of E-cadherin, P-cadherin and N-cadherin in oral squamous cell carcinoma: correlation with the clinicopathologic features and patient outcome.

J Craniomaxillofac Surg 2007 Jan 12;35(1):1-9. Epub 2007 Feb 12.

Department of Oral and Maxillofacial Surgery and Dentistry, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

View Article
January 2007

Collagen I promotes metastasis in pancreatic cancer by activating c-Jun NH(2)-terminal kinase 1 and up-regulating N-cadherin expression.

Cancer Res 2006 Dec;66(24):11745-53

Department of Oral Biology, University of Nebraska Medical Center, Omaha, Nebraska 68198, USA.

View Article
December 2006

Phosphoinositide-3 kinase-Rac1-c-Jun NH2-terminal kinase signaling mediates collagen I-induced cell scattering and up-regulation of N-cadherin expression in mouse mammary epithelial cells.

Mol Biol Cell 2006 Jul 19;17(7):2963-75. Epub 2006 Apr 19.

Department of Oral Biology, Eppley Institute for Research in Cancer and Allied Diseases, and Eppley Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198-7696, USA.

View Article
July 2006

N-cadherin-mediated cell motility requires cis dimers.

Cell Commun Adhes 2005 Jan-Apr;12(1-2):23-39

Department of Oral Biology, College of Dentistry, University of Nebraska Medical Center, Omaha, Nebraska, USA.

View Article
May 2006

Src activation is not necessary for transforming growth factor (TGF)-beta-mediated epithelial to mesenchymal transitions (EMT) in mammary epithelial cells. PP1 directly inhibits TGF-beta receptors I and II.

J Biol Chem 2006 Jan 1;281(1):59-68. Epub 2005 Nov 1.

Department of Oral Biology, College of Dentistry, University of Nebraska Medical Center, Nebraska Medical Center, Omaha 68198-7696, USA.

View Article
January 2006

Modulating the strength of cadherin adhesion: evidence for a novel adhesion complex.

J Cell Sci 2005 Sep 9;118(Pt 17):3883-94. Epub 2005 Aug 9.

University of Nebraska Medical Center, College of Dentistry, 769605 Nebraska Medical Center, Omaha, NE 68583, USA.

View Article
September 2005

Effect of N-cadherin misexpression by the mammary epithelium in mice.

J Cell Biochem 2005 Aug;95(6):1093-107

Lankenau Institute for Medical Research, Wynnewood, Pennsylvania 19096, USA.

View Article
August 2005

Cadherin switching: essential for behavioral but not morphological changes during an epithelium-to-mesenchyme transition.

J Cell Sci 2005 Mar 15;118(Pt 5):873-87. Epub 2005 Feb 15.

Department of Oral Biology (College of Dentistry), University of Nebraska Medical Center, Omaha, NE 68198-7696, USA.

View Article
March 2005

R-cadherin influences cell motility via Rho family GTPases.

J Biol Chem 2004 Jul 13;279(30):31041-9. Epub 2004 May 13.

Department of Oral Biology, College of Dentistry, Eppley Institute for Research in Cancer and Allied Diseases, and Eppley Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska 68198, USA.

View Article
July 2004

Cadherins as modulators of cellular phenotype.

Annu Rev Cell Dev Biol 2003 ;19:207-35

Department of Oral Biology, College of Dentistry and Eppley Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska 68198-7696, USA.

View Article
February 2004

Cadherin-mediated cellular signaling.

Curr Opin Cell Biol 2003 Oct;15(5):509-14

University of Nebraska Medical Center, 987696 Nebraska Medical Center, Omaha, NE 68198-7696, USA.

View Article
October 2003

Nuclear association of the cytoplasmic tail of MUC1 and beta-catenin.

J Biol Chem 2003 Sep 27;278(39):38029-39. Epub 2003 Jun 27.

Eppley Institute for Research in Cancer and Allied Diseases, Omaha, Nebraska 68198-6805, USA.

View Article
September 2003

Characterization of cadherin-24, a novel alternatively spliced type II cadherin.

J Biol Chem 2003 Jul 5;278(30):27513-9. Epub 2003 May 5.

University of Nebraska Medical Center, Department of Oral Biology, College of Dentistry and Eppley Cancer Center, Omaha, Nebraska 68198, USA.

View Article
July 2003

Differential displacement of classical cadherins by VE-cadherin.

Cell Commun Adhes 2002 Mar-Apr;9(2):103-15

Department of Oral Biology and Eppley Institute for Cancer Research, University of Nebraska Medical Center, Omaha, NE 68198-7696, USA.

View Article
May 2003

N-cadherin-catenin complexes form prior to cleavage of the proregion and transport to the plasma membrane.

J Biol Chem 2003 May 25;278(19):17269-76. Epub 2003 Feb 25.

University of Nebraska Medical Center, College of Dentistry and Eppley Cancer Center, Omaha, Nebraska 68198-7696, USA.

View Article
May 2003

Impaired trafficking of connexins in androgen-independent human prostate cancer cell lines and its mitigation by alpha-catenin.

J Biol Chem 2002 Dec 29;277(51):50087-97. Epub 2002 Aug 29.

Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA.

View Article
December 2002

A role for cadherins in cellular signaling and differentiation.

J Cell Biochem 1998 ;72 Suppl 30-31(S30-31):168-176

Department of Biology, University of Toledo, Toledo, OH 43606.

View Article
January 1998