Keith Matthews

Keith Matthews

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Keith Matthews

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Comparison of psychiatric co-morbidity in treatment-seeking, opioid dependent patients with versus without chronic pain.

Addiction 2019 Aug 6. Epub 2019 Aug 6.

Division of Neuroscience, University of Dundee, Mailbox 6, Level 6, Laboratories Block, Ninewells Hospital and Medical School, Dundee, DD1 9SY.

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http://dx.doi.org/10.1111/add.14768DOI Listing
August 2019

Positional Dynamics and Glycosomal Recruitment of Developmental Regulators during Trypanosome Differentiation.

MBio 2019 Jul 9;10(4). Epub 2019 Jul 9.

Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom

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http://dx.doi.org/10.1128/mBio.00875-19DOI Listing
July 2019

A Randomized Trial Directly Comparing Ventral Capsule and Anteromedial Subthalamic Nucleus Stimulation in Obsessive-Compulsive Disorder: Clinical and Imaging Evidence for Dissociable Effects.

Biol Psychiatry 2019 May 30;85(9):726-734. Epub 2019 Jan 30.

Department of Clinical and Movement Neurosciences, University College London Queen Square Institute of Neurology, London, United Kingdom; The National Hospital for Neurology and Neurosurgery, London, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00063223193006
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http://dx.doi.org/10.1016/j.biopsych.2019.01.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467837PMC
May 2019

African trypanosomes.

Parasit Vectors 2019 Apr 29;12(1):190. Epub 2019 Apr 29.

Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1186/s13071-019-3355-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489224PMC
April 2019

Oligopeptide Signaling through TbGPR89 Drives Trypanosome Quorum Sensing.

Cell 2019 Jan 29;176(1-2):306-317.e16. Epub 2018 Nov 29.

Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FL, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.10.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333907PMC
January 2019

Substance misuse in patients who have comorbid chronic pain in a clinical population receiving methadone maintenance therapy for the treatment of opioid dependence.

Drug Alcohol Depend 2018 12 18;193:131-136. Epub 2018 Oct 18.

Division of Neuroscience, University of Dundee, Mailbox 6, Level 6, Laboratories Block, Ninewells Hospital and Medical School, Dundee, DD1 9SY Scotland, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03768716183074
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http://dx.doi.org/10.1016/j.drugalcdep.2018.08.038DOI Listing
December 2018

A gene expression comparison of Trypanosoma brucei and Trypanosoma congolense in the bloodstream of the mammalian host reveals species-specific adaptations to density-dependent development.

PLoS Negl Trop Dis 2018 10 11;12(10):e0006863. Epub 2018 Oct 11.

Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1371/journal.pntd.0006863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199001PMC
October 2018

Mitochondrial DNA is critical for longevity and metabolism of transmission stage Trypanosoma brucei.

PLoS Pathog 2018 07 18;14(7):e1007195. Epub 2018 Jul 18.

Centre for Immunity, Infection and Evolution, Institute of Immunology & Infection Research, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1371/journal.ppat.1007195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066258PMC
July 2018

Analysis of shared heritability in common disorders of the brain.

Authors:
Verneri Anttila Brendan Bulik-Sullivan Hilary K Finucane Raymond K Walters Jose Bras Laramie Duncan Valentina Escott-Price Guido J Falcone Padhraig Gormley Rainer Malik Nikolaos A Patsopoulos Stephan Ripke Zhi Wei Dongmei Yu Phil H Lee Patrick Turley Benjamin Grenier-Boley Vincent Chouraki Yoichiro Kamatani Claudine Berr Luc Letenneur Didier Hannequin Philippe Amouyel Anne Boland Jean-François Deleuze Emmanuelle Duron Badri N Vardarajan Christiane Reitz Alison M Goate Matthew J Huentelman M Ilyas Kamboh Eric B Larson Ekaterina Rogaeva Peter St George-Hyslop Hakon Hakonarson Walter A Kukull Lindsay A Farrer Lisa L Barnes Thomas G Beach F Yesim Demirci Elizabeth Head Christine M Hulette Gregory A Jicha John S K Kauwe Jeffrey A Kaye James B Leverenz Allan I Levey Andrew P Lieberman Vernon S Pankratz Wayne W Poon Joseph F Quinn Andrew J Saykin Lon S Schneider Amanda G Smith Joshua A Sonnen Robert A Stern Vivianna M Van Deerlin Linda J Van Eldik Denise Harold Giancarlo Russo David C Rubinsztein Anthony Bayer Magda Tsolaki Petra Proitsi Nick C Fox Harald Hampel Michael J Owen Simon Mead Peter Passmore Kevin Morgan Markus M Nöthen Martin Rossor Michelle K Lupton Per Hoffmann Johannes Kornhuber Brian Lawlor Andrew McQuillin Ammar Al-Chalabi Joshua C Bis Agustin Ruiz Mercè Boada Sudha Seshadri Alexa Beiser Kenneth Rice Sven J van der Lee Philip L De Jager Daniel H Geschwind Matthias Riemenschneider Steffi Riedel-Heller Jerome I Rotter Gerhard Ransmayr Bradley T Hyman Carlos Cruchaga Montserrat Alegret Bendik Winsvold Priit Palta Kai-How Farh Ester Cuenca-Leon Nicholas Furlotte Tobias Kurth Lannie Ligthart Gisela M Terwindt Tobias Freilinger Caroline Ran Scott D Gordon Guntram Borck Hieab H H Adams Terho Lehtimäki Juho Wedenoja Julie E Buring Markus Schürks Maria Hrafnsdottir Jouke-Jan Hottenga Brenda Penninx Ville Artto Mari Kaunisto Salli Vepsäläinen Nicholas G Martin Grant W Montgomery Mitja I Kurki Eija Hämäläinen Hailiang Huang Jie Huang Cynthia Sandor Caleb Webber Bertram Muller-Myhsok Stefan Schreiber Veikko Salomaa Elizabeth Loehrer Hartmut Göbel Alfons Macaya Patricia Pozo-Rosich Thomas Hansen Thomas Werge Jaakko Kaprio Andres Metspalu Christian Kubisch Michel D Ferrari Andrea C Belin Arn M J M van den Maagdenberg John-Anker Zwart Dorret Boomsma Nicholas Eriksson Jes Olesen Daniel I Chasman Dale R Nyholt Andreja Avbersek Larry Baum Samuel Berkovic Jonathan Bradfield Russell J Buono Claudia B Catarino Patrick Cossette Peter De Jonghe Chantal Depondt Dennis Dlugos Thomas N Ferraro Jacqueline French Helle Hjalgrim Jennifer Jamnadas-Khoda Reetta Kälviäinen Wolfram S Kunz Holger Lerche Costin Leu Dick Lindhout Warren Lo Daniel Lowenstein Mark McCormack Rikke S Møller Anne Molloy Ping-Wing Ng Karen Oliver Michael Privitera Rodney Radtke Ann-Kathrin Ruppert Thomas Sander Steven Schachter Christoph Schankin Ingrid Scheffer Susanne Schoch Sanjay M Sisodiya Philip Smith Michael Sperling Pasquale Striano Rainer Surges G Neil Thomas Frank Visscher Christopher D Whelan Federico Zara Erin L Heinzen Anthony Marson Felicitas Becker Hans Stroink Fritz Zimprich Thomas Gasser Raphael Gibbs Peter Heutink Maria Martinez Huw R Morris Manu Sharma Mina Ryten Kin Y Mok Sara Pulit Steve Bevan Elizabeth Holliday John Attia Thomas Battey Giorgio Boncoraglio Vincent Thijs Wei-Min Chen Braxton Mitchell Peter Rothwell Pankaj Sharma Cathie Sudlow Astrid Vicente Hugh Markus Christina Kourkoulis Joana Pera Miriam Raffeld Scott Silliman Vesna Boraska Perica Laura M Thornton Laura M Huckins N William Rayner Cathryn M Lewis Monica Gratacos Filip Rybakowski Anna Keski-Rahkonen Anu Raevuori James I Hudson Ted Reichborn-Kjennerud Palmiero Monteleone Andreas Karwautz Katrin Mannik Jessica H Baker Julie K O'Toole Sara E Trace Oliver S P Davis Sietske G Helder Stefan Ehrlich Beate Herpertz-Dahlmann Unna N Danner Annemarie A van Elburg Maurizio Clementi Monica Forzan Elisa Docampo Jolanta Lissowska Joanna Hauser Alfonso Tortorella Mario Maj Fragiskos Gonidakis Konstantinos Tziouvas Hana Papezova Zeynep Yilmaz Gudrun Wagner Sarah Cohen-Woods Stefan Herms Antonio Julià Raquel Rabionet Danielle M Dick Samuli Ripatti Ole A Andreassen Thomas Espeseth Astri J Lundervold Vidar M Steen Dalila Pinto Stephen W Scherer Harald Aschauer Alexandra Schosser Lars Alfredsson Leonid Padyukov Katherine A Halmi James Mitchell Michael Strober Andrew W Bergen Walter Kaye Jin Peng Szatkiewicz Bru Cormand Josep Antoni Ramos-Quiroga Cristina Sánchez-Mora Marta Ribasés Miguel Casas Amaia Hervas Maria Jesús Arranz Jan Haavik Tetyana Zayats Stefan Johansson Nigel Williams Astrid Dempfle Aribert Rothenberger Jonna Kuntsi Robert D Oades Tobias Banaschewski Barbara Franke Jan K Buitelaar Alejandro Arias Vasquez Alysa E Doyle Andreas Reif Klaus-Peter Lesch Christine Freitag Olga Rivero Haukur Palmason Marcel Romanos Kate Langley Marcella Rietschel Stephanie H Witt Soeren Dalsgaard Anders D Børglum Irwin Waldman Beth Wilmot Nikolas Molly Claiton H D Bau Jennifer Crosbie Russell Schachar Sandra K Loo James J McGough Eugenio H Grevet Sarah E Medland Elise Robinson Lauren A Weiss Elena Bacchelli Anthony Bailey Vanessa Bal Agatino Battaglia Catalina Betancur Patrick Bolton Rita Cantor Patrícia Celestino-Soper Geraldine Dawson Silvia De Rubeis Frederico Duque Andrew Green Sabine M Klauck Marion Leboyer Pat Levitt Elena Maestrini Shrikant Mane Daniel Moreno- De-Luca Jeremy Parr Regina Regan Abraham Reichenberg Sven Sandin Jacob Vorstman Thomas Wassink Ellen Wijsman Edwin Cook Susan Santangelo Richard Delorme Bernadette Rogé Tiago Magalhaes Dan Arking Thomas G Schulze Robert C Thompson Jana Strohmaier Keith Matthews Ingrid Melle Derek Morris Douglas Blackwood Andrew McIntosh Sarah E Bergen Martin Schalling Stéphane Jamain Anna Maaser Sascha B Fischer Céline S Reinbold Janice M Fullerton José Guzman-Parra Fermin Mayoral Peter R Schofield Sven Cichon Thomas W Mühleisen Franziska Degenhardt Johannes Schumacher Michael Bauer Philip B Mitchell Elliot S Gershon John Rice James B Potash Peter P Zandi Nick Craddock I Nicol Ferrier Martin Alda Guy A Rouleau Gustavo Turecki Roel Ophoff Carlos Pato Adebayo Anjorin Eli Stahl Markus Leber Piotr M Czerski Cristiana Cruceanu Ian R Jones Danielle Posthuma Till F M Andlauer Andreas J Forstner Fabian Streit Bernhard T Baune Tracy Air Grant Sinnamon Naomi R Wray Donald J MacIntyre David Porteous Georg Homuth Margarita Rivera Jakob Grove Christel M Middeldorp Ian Hickie Michele Pergadia Divya Mehta Johannes H Smit Rick Jansen Eco de Geus Erin Dunn Qingqin S Li Matthias Nauck Robert A Schoevers Aartjan Tf Beekman James A Knowles Alexander Viktorin Paul Arnold Cathy L Barr Gabriel Bedoya-Berrio O Joseph Bienvenu Helena Brentani Christie Burton Beatriz Camarena Carolina Cappi Danielle Cath Maria Cavallini Daniele Cusi Sabrina Darrow Damiaan Denys Eske M Derks Andrea Dietrich Thomas Fernandez Martijn Figee Nelson Freimer Gloria Gerber Marco Grados Erica Greenberg Gregory L Hanna Andreas Hartmann Matthew E Hirschtritt Pieter J Hoekstra Alden Huang Chaim Huyser Cornelia Illmann Michael Jenike Samuel Kuperman Bennett Leventhal Christine Lochner Gholson J Lyon Fabio Macciardi Marcos Madruga-Garrido Irene A Malaty Athanasios Maras Lauren McGrath Eurípedes C Miguel Pablo Mir Gerald Nestadt Humberto Nicolini Michael S Okun Andrew Pakstis Peristera Paschou John Piacentini Christopher Pittenger Kerstin Plessen Vasily Ramensky Eliana M Ramos Victor Reus Margaret A Richter Mark A Riddle Mary M Robertson Veit Roessner Maria Rosário Jack F Samuels Paul Sandor Dan J Stein Fotis Tsetsos Filip Van Nieuwerburgh Sarah Weatherall Jens R Wendland Tomasz Wolanczyk Yulia Worbe Gwyneth Zai Fernando S Goes Nicole McLaughlin Paul S Nestadt Hans-Jorgen Grabe Christel Depienne Anuar Konkashbaev Nuria Lanzagorta Ana Valencia-Duarte Elvira Bramon Nancy Buccola Wiepke Cahn Murray Cairns Siow A Chong David Cohen Benedicto Crespo-Facorro James Crowley Michael Davidson Lynn DeLisi Timothy Dinan Gary Donohoe Elodie Drapeau Jubao Duan Lieuwe Haan David Hougaard Sena Karachanak-Yankova Andrey Khrunin Janis Klovins Vaidutis Kučinskas Jimmy Lee Chee Keong Svetlana Limborska Carmel Loughland Jouko Lönnqvist Brion Maher Manuel Mattheisen Colm McDonald Kieran C Murphy Igor Nenadic Jim van Os Christos Pantelis Michele Pato Tracey Petryshen Digby Quested Panos Roussos Alan R Sanders Ulrich Schall Sibylle G Schwab Kang Sim Hon-Cheong So Elisabeth Stögmann Mythily Subramaniam Draga Toncheva John Waddington James Walters Mark Weiser Wei Cheng Robert Cloninger David Curtis Pablo V Gejman Frans Henskens Morten Mattingsdal Sang-Yun Oh Rodney Scott Bradley Webb Gerome Breen Claire Churchhouse Cynthia M Bulik Mark Daly Martin Dichgans Stephen V Faraone Rita Guerreiro Peter Holmans Kenneth S Kendler Bobby Koeleman Carol A Mathews Alkes Price Jeremiah Scharf Pamela Sklar Julie Williams Nicholas W Wood Chris Cotsapas Aarno Palotie Jordan W Smoller Patrick Sullivan Jonathan Rosand Aiden Corvin Benjamin M Neale Jonathan M Schott Richard Anney Josephine Elia Maria Grigoroiu-Serbanescu Howard J Edenberg Robin Murray

Science 2018 06;360(6395)

Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

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http://dx.doi.org/10.1126/science.aap8757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097237PMC
June 2018

Non-linear hierarchy of the quorum sensing signalling pathway in bloodstream form African trypanosomes.

PLoS Pathog 2018 06 25;14(6):e1007145. Epub 2018 Jun 25.

Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1371/journal.ppat.1007145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034907PMC
June 2018

Compulsivity in opioid dependence.

Prog Neuropsychopharmacol Biol Psychiatry 2018 Feb 14;81:333-339. Epub 2017 Sep 14.

St Andrews University, Division of Population and Behavioural Sciences, School of Medicine, St Andrews, Fife, UK. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2017.09.007DOI Listing
February 2018

Emerging challenges in understanding trypanosome antigenic variation.

Emerg Top Life Sci 2017 Dec;1(6):585-592

Immune Diversity (D150), Division Immunology, German Cancer Research Center, Im Neuenheimer Feld 280, Heidelberg 69120, Germany.

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http://dx.doi.org/10.1042/ETLS20170104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162063PMC
December 2017

Interspecies quorum sensing in co-infections can manipulate trypanosome transmission potential.

Nat Microbiol 2017 Nov 4;2(11):1471-1479. Epub 2017 Sep 4.

Centre for Immunity, Infection and Evolution, Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3FL, UK.

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http://dx.doi.org/10.1038/s41564-017-0014-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660621PMC
November 2017

The Cytological Events and Molecular Control of Life Cycle Development of Trypanosoma brucei in the Mammalian Bloodstream.

Pathogens 2017 Jun 28;6(3). Epub 2017 Jun 28.

Institute for Immunology and Infection Research, Centre for Immunity, Infection and Evolution, School of Biological Sciences, King's Buildings, University of Edinburgh, Charlotte Auerbach Road, Edinburgh EH9 3FL, UK.

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http://dx.doi.org/10.3390/pathogens6030029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617986PMC
June 2017

Genome-wide RNAi selection identifies a regulator of transmission stage-enriched gene families and cell-type differentiation in Trypanosoma brucei.

PLoS Pathog 2017 03 23;13(3):e1006279. Epub 2017 Mar 23.

Centre for Immunity, Infection and Evolution, Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, Scotland, United Kingdom.

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http://dx.doi.org/10.1371/journal.ppat.1006279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380359PMC
March 2017

Targeting pathogen metabolism without collateral damage to the host.

Sci Rep 2017 01 13;7:40406. Epub 2017 Jan 13.

University of Groningen, University Medical Center Groningen, Department of Pediatrics and Systems Biology Centre for Energy Metabolism and Ageing, Center for Liver, Digestive and Metabolic Diseases, Groningen, The Netherlands.

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http://dx.doi.org/10.1038/srep40406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234033PMC
January 2017

Neurosurgical Treatments for Patients with Chronic, Treatment-Refractory Depression: A Retrospective, Consecutive, Case Series Comparison of Anterior Capsulotomy, Anterior Cingulotomy and Vagus Nerve Stimulation.

Stereotact Funct Neurosurg 2015 16;93(6):387-92. Epub 2015 Dec 16.

Advanced Interventions Service, NHS Tayside, and Division of Neuroscience, University of Dundee, Dundee, UK.

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http://dx.doi.org/10.1159/000439115DOI Listing
December 2016

Autobiographical memory specificity in response to verbal and pictorial cues in clinical depression.

J Behav Ther Exp Psychiatry 2016 Jun 13;51:109-15. Epub 2016 Jan 13.

Department of Psychology, University of Stirling, Stirling, FK9 4LA, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00057916163000
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http://dx.doi.org/10.1016/j.jbtep.2016.01.002DOI Listing
June 2016

A causal role for the anterior mid-cingulate cortex in negative affect and cognitive control.

Brain 2016 06 28;139(Pt 6):1844-54. Epub 2016 Apr 28.

School of Medicine (Neuroscience), Ninewells Hospital and Medical School, University of Dundee, UK Advanced Interventions Service, Area 7, Level 6, South Block, Ninewells Hospital and Medical School, UK

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http://dx.doi.org/10.1093/brain/aww069DOI Listing
June 2016

Drug resistance in eukaryotic microorganisms.

Nat Microbiol 2016 06 24;1(7):16092. Epub 2016 Jun 24.

Wellcome Trust Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical and Veterinary Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.

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http://dx.doi.org/10.1038/nmicrobiol.2016.92DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215055PMC
June 2016

Structural MRI-Based Predictions in Patients with Treatment-Refractory Depression (TRD).

PLoS One 2015 17;10(7):e0132958. Epub 2015 Jul 17.

Division of Neuroscience, Medical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee, United Kingdom; Advanced Interventions Service, Area 7, Level 6, South Block, Ninewells Hospital and Medical School, NHS Tayside, Dundee, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0132958PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506147PMC
May 2016

25 years of African trypanosome research: From description to molecular dissection and new drug discovery.

Authors:
Keith R Matthews

Mol Biochem Parasitol 2015 Mar-Apr;200(1-2):30-40. Epub 2015 Feb 28.

Centre for Immunity, Infection and Evolution, Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.molbiopara.2015.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509711PMC
March 2016

Molecular control of irreversible bistability during trypanosome developmental commitment.

J Cell Biol 2015 Oct 19;211(2):455-68. Epub 2015 Oct 19.

Centre for Immunity, Infection and Evolution, Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, Scotland, UK

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http://dx.doi.org/10.1083/jcb.201506114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621835PMC
October 2015

Failure of hippocampal deactivation during loss events in treatment-resistant depression.

Brain 2015 Sep 30;138(Pt 9):2766-76. Epub 2015 Jun 30.

1 Division of Neuroscience, Medical Research Institute, Ninewells Hospital and Medical School, University of Dundee, U.K, DD1 9SY 3 Advanced Interventions Service, Area 7, Level 6, South Block, Ninewells Hospital and Medical School, Dundee, UK

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http://dx.doi.org/10.1093/brain/awv177DOI Listing
September 2015

The within-host dynamics of African trypanosome infections.

Philos Trans R Soc Lond B Biol Sci 2015 Aug;370(1675)

Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528486PMC
http://dx.doi.org/10.1098/rstb.2014.0288DOI Listing
August 2015

Efficacy of cognitive-behavioral therapy for obsessive-compulsive disorder.

Psychiatry Res 2015 Feb 8;225(3):236-46. Epub 2014 Dec 8.

NIHR Specialist Biomedical Research Centre for Mental Health at the South London and Maudsley NHS Foundation Trust and The Institute of Psychiatry, King׳s College London, UK.

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http://dx.doi.org/10.1016/j.psychres.2014.11.058DOI Listing
February 2015

Obsessive-compulsive disorder (OCD): Practical strategies for pharmacological and somatic treatment in adults.

Psychiatry Res 2015 May 11;227(1):114-25. Epub 2015 Feb 11.

Obsessive Compulsive Disorder Clinic, Department of Psychology, McGill University Health Centre, and Department of Psychiatry, McGill University, Montreal, PQ, Canada.

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http://dx.doi.org/10.1016/j.psychres.2014.12.003DOI Listing
May 2015

NMD3 regulates both mRNA and rRNA nuclear export in African trypanosomes via an XPOI-linked pathway.

Nucleic Acids Res 2015 May 14;43(9):4491-504. Epub 2015 Apr 14.

Centre for Immunity, Infection and Evolution, Institute for Immunology and Infection Research, School of Biological Sciences, Kings Buildings, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, UK

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http://dx.doi.org/10.1093/nar/gkv330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482084PMC
May 2015

Efficacy of cognitive-behavioral therapy for obsessive-compulsive disorder.

Psychiatry Res 2015 May;227(1):104-13

NIHR Specialist Biomedical Research Centre for Mental Health at the South London and Maudsley NHS Foundation Trust, UK; The Institute of Psychiatry, King׳s College London, UK.

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http://dx.doi.org/10.1016/j.psychres.2015.02.004DOI Listing
May 2015

Assembling the components of the quorum sensing pathway in African trypanosomes.

Mol Microbiol 2015 Apr 4;96(2):220-32. Epub 2015 Mar 4.

Centre for Immunity, Infection and Evolution, Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Charlotte Auerbach Road, Edinburgh, EH9 3FL, UK.

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http://dx.doi.org/10.1111/mmi.12949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403954PMC
April 2015

Somatic symptom count scores do not identify patients with symptoms unexplained by disease: a prospective cohort study of neurology outpatients.

J Neurol Neurosurg Psychiatry 2015 Mar 16;86(3):295-301. Epub 2014 Jun 16.

Department of Psychiatry, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1136/jnnp-2014-308234DOI Listing
March 2015

Efficacy of cognitive-behavioral therapy for obsessive-compulsive disorder.

Psychiatry Res 2015 Feb 8;225(3):236-46. Epub 2014 Dec 8.

NIHR Specialist Biomedical Research Centre for Mental Health at the South London and Maudsley NHS Foundation Trust and The Institute of Psychiatry, King׳s College London, UK.

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http://dx.doi.org/10.1016/j.psychres.2014.11.058DOI Listing
February 2015

Predicting methylphenidate response in attention deficit hyperactivity disorder: a preliminary study.

J Psychopharmacol 2015 Jan 18;29(1):24-30. Epub 2014 Sep 18.

Division of Neuroscience, Medical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.

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http://dx.doi.org/10.1177/0269881114548438DOI Listing
January 2015

Brainstem abnormalities in attention deficit hyperactivity disorder support high accuracy individual diagnostic classification.

Hum Brain Mapp 2014 Oct 13;35(10):5179-89. Epub 2014 May 13.

Division of Neuroscience, Medical Research Institute, Ninewells Hospital and Medical School, University of Dundee, United Kingdom.

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http://dx.doi.org/10.1002/hbm.22542DOI Listing
October 2014

Transcriptome-wide analysis of trypanosome mRNA decay reveals complex degradation kinetics and suggests a role for co-transcriptional degradation in determining mRNA levels.

Mol Microbiol 2014 Oct 15;94(2):307-26. Epub 2014 Sep 15.

Zentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 282, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1111/mmi.12764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285177PMC
October 2014

Consensus on guidelines for stereotactic neurosurgery for psychiatric disorders.

J Neurol Neurosurg Psychiatry 2014 Sep 20;85(9):1003-8. Epub 2014 Jan 20.

Working Group 'Deep Brain Stimulation in Psychiatry: Guidance for Responsible Research and Application'. This Working Group is organised by the Europäische Akademie GmbH (Bad Neuenahr-Ahrweiler, Germany, http://www.ea-aw.de). It consists of an interdisciplinary and international team of neurosurgeons, neurologists, psychiatrists, neuropsychologists, bioethicists, philosophers and legal scholars, analysing ethical issues arising from the application of Deep Brain Stimulation for Psychiatric Disorders. Questions such as critical issues around regulatory processes and ethical guidance for the management of conflicts of interest for researchers, engineers and clinicians engaged in the development of therapeutic deep brain stimulation have been comprehensively studied and the results have been published under common authorship. Chair of the Focus Group 'Deep Brain Stimulation in Psychiatry: Guidance for Responsible Research and Application', Chair of the Task Force on Brain Stimulation of the World Federations of Societies of Biological Psychiatry, Chair of the Section of Experimental Brain Stimulation Methods of the German Association of Psychiatry, Psychotherapy and Psychosomatics and member of the Operational Committee on Sections of the World Psychiatric Association. He is professor of Psychiatry and Psychotherapy at the University of Bonn, Germany, and Associate Professor of Psychiatry and Mental Health at The Johns Hopkins University, Baltimore, MD, USA.

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http://www.psychiatry.wisc.edu/downloads/mayberg1.pdf
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September 2014

Factors associated with high burden in caregivers of older adults with cancer.

Cancer 2014 Sep 4;120(18):2927-35. Epub 2014 Jun 4.

Department of Medical Oncology and Therapeutics Research, City of Hope National Medical Center, Duarte, California.

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September 2014

Independent pathways can transduce the life-cycle differentiation signal in Trypanosoma brucei.

PLoS Pathog 2013 17;9(10):e1003689. Epub 2013 Oct 17.

Centre for Immunity, Infection and Evolution, Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.

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May 2014

Identifying older heart failure patients with major depression in primary care: a feasibility study.

Int J Geriatr Psychiatry 2014 May;29(5):547-9

Ageing and Health, University of Dundee, Dundee, UK.

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May 2014

Bloodstream form pre-adaptation to the tsetse fly in Trypanosoma brucei.

Front Cell Infect Microbiol 2013 14;3:78. Epub 2013 Nov 14.

Centre for Immunity, Infection and Evolution, School of Biological Sciences, University of Edinburgh Edinburgh, UK.

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April 2014

Abnormal brain activity during a reward and loss task in opiate-dependent patients receiving methadone maintenance therapy.

Neuropsychopharmacology 2014 Mar 17;39(4):885-94. Epub 2013 Oct 17.

Department of Psychiatry, Medical Research Institute, University of Dundee, Dundee, UK.

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March 2014

High-throughput chemical screening for antivirulence developmental phenotypes in Trypanosoma brucei.

Eukaryot Cell 2014 Mar 17;13(3):412-26. Epub 2014 Jan 17.

Centre for Immunity, Infection and Evolution, Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.

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March 2014

Cognitive Behavioural Analysis System of Psychotherapy (CBASP) for chronic depression: clinical characteristics and six month clinical outcomes in an open case series.

J Affect Disord 2014 Jan 5;152-154:268-76. Epub 2013 Oct 5.

Division of Neuroscience, Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, UK. Electronic address:

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January 2014

Genome-wide dissection of the quorum sensing signalling pathway in Trypanosoma brucei.

Nature 2014 Jan 15;505(7485):681-685. Epub 2013 Dec 15.

Centre for Immunity, Infection and Evolution, Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, EH9 3JT, United Kingdom.

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January 2014

The clinical utility of different quantitative methods for measuring treatment resistance in major depression.

J Affect Disord 2013 Sep 11;150(2):231-6. Epub 2013 May 11.

Northamptonshire Healthcare NHS Foundation Trust, Northampton, United Kingdom.

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September 2013

Vagus nerve stimulation for chronic major depressive disorder: 12-month outcomes in highly treatment-refractory patients.

J Affect Disord 2013 Sep 29;150(3):1221-5. Epub 2013 Jun 29.

Advanced Interventions Service, NHS Tayside, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.

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September 2013

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.

Authors:
S Hong Lee Stephan Ripke Benjamin M Neale Stephen V Faraone Shaun M Purcell Roy H Perlis Bryan J Mowry Anita Thapar Michael E Goddard John S Witte Devin Absher Ingrid Agartz Huda Akil Farooq Amin Ole A Andreassen Adebayo Anjorin Richard Anney Verneri Anttila Dan E Arking Philip Asherson Maria H Azevedo Lena Backlund Judith A Badner Anthony J Bailey Tobias Banaschewski Jack D Barchas Michael R Barnes Thomas B Barrett Nicholas Bass Agatino Battaglia Michael Bauer Mònica Bayés Frank Bellivier Sarah E Bergen Wade Berrettini Catalina Betancur Thomas Bettecken Joseph Biederman Elisabeth B Binder Donald W Black Douglas H R Blackwood Cinnamon S Bloss Michael Boehnke Dorret I Boomsma Gerome Breen René Breuer Richard Bruggeman Paul Cormican Nancy G Buccola Jan K Buitelaar William E Bunney Joseph D Buxbaum William F Byerley Enda M Byrne Sian Caesar Wiepke Cahn Rita M Cantor Miguel Casas Aravinda Chakravarti Kimberly Chambert Khalid Choudhury Sven Cichon C Robert Cloninger David A Collier Edwin H Cook Hilary Coon Bru Cormand Aiden Corvin William H Coryell David W Craig Ian W Craig Jennifer Crosbie Michael L Cuccaro David Curtis Darina Czamara Susmita Datta Geraldine Dawson Richard Day Eco J De Geus Franziska Degenhardt Srdjan Djurovic Gary J Donohoe Alysa E Doyle Jubao Duan Frank Dudbridge Eftichia Duketis Richard P Ebstein Howard J Edenberg Josephine Elia Sean Ennis Bruno Etain Ayman Fanous Anne E Farmer I Nicol Ferrier Matthew Flickinger Eric Fombonne Tatiana Foroud Josef Frank Barbara Franke Christine Fraser Robert Freedman Nelson B Freimer Christine M Freitag Marion Friedl Louise Frisén Louise Gallagher Pablo V Gejman Lyudmila Georgieva Elliot S Gershon Daniel H Geschwind Ina Giegling Michael Gill Scott D Gordon Katherine Gordon-Smith Elaine K Green Tiffany A Greenwood Dorothy E Grice Magdalena Gross Detelina Grozeva Weihua Guan Hugh Gurling Lieuwe De Haan Jonathan L Haines Hakon Hakonarson Joachim Hallmayer Steven P Hamilton Marian L Hamshere Thomas F Hansen Annette M Hartmann Martin Hautzinger Andrew C Heath Anjali K Henders Stefan Herms Ian B Hickie Maria Hipolito Susanne Hoefels Peter A Holmans Florian Holsboer Witte J Hoogendijk Jouke-Jan Hottenga Christina M Hultman Vanessa Hus Andrés Ingason Marcus Ising Stéphane Jamain Edward G Jones Ian Jones Lisa Jones Jung-Ying Tzeng Anna K Kähler René S Kahn Radhika Kandaswamy Matthew C Keller James L Kennedy Elaine Kenny Lindsey Kent Yunjung Kim George K Kirov Sabine M Klauck Lambertus Klei James A Knowles Martin A Kohli Daniel L Koller Bettina Konte Ania Korszun Lydia Krabbendam Robert Krasucki Jonna Kuntsi Phoenix Kwan Mikael Landén Niklas Långström Mark Lathrop Jacob Lawrence William B Lawson Marion Leboyer David H Ledbetter Phil H Lee Todd Lencz Klaus-Peter Lesch Douglas F Levinson Cathryn M Lewis Jun Li Paul Lichtenstein Jeffrey A Lieberman Dan-Yu Lin Don H Linszen Chunyu Liu Falk W Lohoff Sandra K Loo Catherine Lord Jennifer K Lowe Susanne Lucae Donald J MacIntyre Pamela A F Madden Elena Maestrini Patrik K E Magnusson Pamela B Mahon Wolfgang Maier Anil K Malhotra Shrikant M Mane Christa L Martin Nicholas G Martin Manuel Mattheisen Keith Matthews Morten Mattingsdal Steven A McCarroll Kevin A McGhee James J McGough Patrick J McGrath Peter McGuffin Melvin G McInnis Andrew McIntosh Rebecca McKinney Alan W McLean Francis J McMahon William M McMahon Andrew McQuillin Helena Medeiros Sarah E Medland Sandra Meier Ingrid Melle Fan Meng Jobst Meyer Christel M Middeldorp Lefkos Middleton Vihra Milanova Ana Miranda Anthony P Monaco Grant W Montgomery Jennifer L Moran Daniel Moreno-De-Luca Gunnar Morken Derek W Morris Eric M Morrow Valentina Moskvina Pierandrea Muglia Thomas W Mühleisen Walter J Muir Bertram Müller-Myhsok Michael Murtha Richard M Myers Inez Myin-Germeys Michael C Neale Stan F Nelson Caroline M Nievergelt Ivan Nikolov Vishwajit Nimgaonkar Willem A Nolen Markus M Nöthen John I Nurnberger Evaristus A Nwulia Dale R Nyholt Colm O'Dushlaine Robert D Oades Ann Olincy Guiomar Oliveira Line Olsen Roel A Ophoff Urban Osby Michael J Owen Aarno Palotie Jeremy R Parr Andrew D Paterson Carlos N Pato Michele T Pato Brenda W Penninx Michele L Pergadia Margaret A Pericak-Vance Benjamin S Pickard Jonathan Pimm Joseph Piven Danielle Posthuma James B Potash Fritz Poustka Peter Propping Vinay Puri Digby J Quested Emma M Quinn Josep Antoni Ramos-Quiroga Henrik B Rasmussen Soumya Raychaudhuri Karola Rehnström Andreas Reif Marta Ribasés John P Rice Marcella Rietschel Kathryn Roeder Herbert Roeyers Lizzy Rossin Aribert Rothenberger Guy Rouleau Douglas Ruderfer Dan Rujescu Alan R Sanders Stephan J Sanders Susan L Santangelo Joseph A Sergeant Russell Schachar Martin Schalling Alan F Schatzberg William A Scheftner Gerard D Schellenberg Stephen W Scherer Nicholas J Schork Thomas G Schulze Johannes Schumacher Markus Schwarz Edward Scolnick Laura J Scott Jianxin Shi Paul D Shilling Stanley I Shyn Jeremy M Silverman Susan L Slager Susan L Smalley Johannes H Smit Erin N Smith Edmund J S Sonuga-Barke David St Clair Matthew State Michael Steffens Hans-Christoph Steinhausen John S Strauss Jana Strohmaier T Scott Stroup James S Sutcliffe Peter Szatmari Szabocls Szelinger Srinivasa Thirumalai Robert C Thompson Alexandre A Todorov Federica Tozzi Jens Treutlein Manfred Uhr Edwin J C G van den Oord Gerard Van Grootheest Jim Van Os Astrid M Vicente Veronica J Vieland John B Vincent Peter M Visscher Christopher A Walsh Thomas H Wassink Stanley J Watson Myrna M Weissman Thomas Werge Thomas F Wienker Ellen M Wijsman Gonneke Willemsen Nigel Williams A Jeremy Willsey Stephanie H Witt Wei Xu Allan H Young Timothy W Yu Stanley Zammit Peter P Zandi Peng Zhang Frans G Zitman Sebastian Zöllner Bernie Devlin John R Kelsoe Pamela Sklar Mark J Daly Michael C O'Donovan Nicholas Craddock Patrick F Sullivan Jordan W Smoller Kenneth S Kendler Naomi R Wray

Nat Genet 2013 Sep 11;45(9):984-94. Epub 2013 Aug 11.

The University of Queensland, Queensland Brain Institute, Brisbane, Queensland, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800159PMC
September 2013

Stable transformation of pleomorphic bloodstream form Trypanosoma brucei.

Mol Biochem Parasitol 2013 Aug 5;190(2):60-2. Epub 2013 Jul 5.

Centre for Immunity, Infection and Evolution, Institute for Immunology and Infection Research, School of Biological Sciences, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1016/j.molbiopara.2013.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003390PMC
August 2013

Metabolomics guides rational development of a simplified cell culture medium for drug screening against Trypanosoma brucei.

Antimicrob Agents Chemother 2013 Jun 9;57(6):2768-79. Epub 2013 Apr 9.

Wellcome Trust Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.

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http://dx.doi.org/10.1128/AAC.00044-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716122PMC
June 2013

A short bifunctional element operates to positively or negatively regulate ESAG9 expression in different developmental forms of Trypanosoma brucei.

J Cell Sci 2013 May 22;126(Pt 10):2294-304. Epub 2013 Mar 22.

Centre for Immunity, Infection and Evolution, Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, King's Buildings, West Mains Road, Edinburgh, EH9 3JT, UK.

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http://dx.doi.org/10.1242/jcs.126011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672941PMC
May 2013

Investigating mammalian tyrosine phosphatase inhibitors as potential 'piggyback' leads to target Trypanosoma brucei transmission.

Chem Biol Drug Des 2013 Feb;81(2):291-301

Centre for Immunity, Infection and Evolution, School of Biological Sciences, Institute of Immunology and Infection Research, University of Edinburgh, King's Building, West Mains Road, Edinburgh EH9 3JT, UK.

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http://dx.doi.org/10.1111/cbdd.12079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003393PMC
February 2013

Salience network-midbrain dysconnectivity and blunted reward signals in schizophrenia.

Psychiatry Res 2013 Feb 10;211(2):104-11. Epub 2012 Nov 10.

Medical Research Institute, University of Dundee, Dundee, UK.

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http://dx.doi.org/10.1016/j.pscychresns.2012.06.003DOI Listing
February 2013

Solitary solid renal mass: can we predict malignancy?

BJU Int 2012 Dec 22;110(11 Pt B):E548-52. Epub 2012 May 22.

Divisions of Urology, McGill University Health Centre, Montreal, QC, Canada.

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December 2012

Targeting new drugs with choline metabolism.

Int Innov 2012 Oct(Oct):18-21

University of Edinburgh.

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October 2012

Identification of the regulatory elements controlling the transmission stage-specific gene expression of PAD1 in Trypanosoma brucei.

Nucleic Acids Res 2012 Sep 7;40(16):7705-17. Epub 2012 Jun 7.

Centre for Immunity, Infection and Evolution, Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, King's buildings, West Mains Road, Edinburgh, EH9 3JTU, UK.

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http://dx.doi.org/10.1093/nar/gks533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439917PMC
September 2012

Multi-centre diagnostic classification of individual structural neuroimaging scans from patients with major depressive disorder.

Brain 2012 May;135(Pt 5):1508-21

Division of Neuroscience, Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.

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May 2012

The post-transcriptional trans-acting regulator, TbZFP3, co-ordinates transmission-stage enriched mRNAs in Trypanosoma brucei.

Nucleic Acids Res 2012 Apr 2;40(7):2869-83. Epub 2011 Dec 2.

Centre for Immunity, Infection and Evolution, Institute of Immunology and Infection Research, School of Biological Sciences, King's Buildings, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326296PMC
April 2012

Trypanosomal immune evasion, chronicity and transmission: an elegant balancing act.

Nat Rev Microbiol 2012 Apr 30;10(6):431-8. Epub 2012 Apr 30.

Centre for Immunity, Infection and Evolution, Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, King's Buildings, West Mains Road, Edinburgh EH9 3JT, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834543PMC
April 2012

Harnessing evolutionary biology to combat infectious disease.

Nat Med 2012 Feb 6;18(2):217-20. Epub 2012 Feb 6.

Centre for Immunity, Infection and Evolution, School of Biological Sciences, University of Edinburgh, Edinburgh, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712261PMC
February 2012

Prediction of illness severity in patients with major depression using structural MR brain scans.

J Magn Reson Imaging 2012 Jan 29;35(1):64-71. Epub 2011 Sep 29.

Centre for Neuroscience, Division of Medical Sciences, Ninewells Hospital and Medical School, University of Dundee, Dundee, United Kingdom.

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January 2012

Targeting cattle-borne zoonoses and cattle pathogens using a novel trypanosomatid-based delivery system.

PLoS Pathog 2011 Oct 27;7(10):e1002340. Epub 2011 Oct 27.

Centre for Immunity, Infection and Evolution, Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.

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October 2011

The insular cortex and the neuroanatomy of major depression.

J Affect Disord 2011 Sep 29;133(1-2):120-7. Epub 2011 Apr 29.

University of St Andrews, School of Psychology, St Andrews, UK.

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September 2011

Long term outcome of thermal anterior capsulotomy for chronic, treatment refractory depression.

J Neurol Neurosurg Psychiatry 2011 Jun 15;82(6):594-600. Epub 2010 Dec 15.

Advanced Interventions Service, Area 7, Level 6, South Block, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.

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June 2011

Malaria and trypanosome transmission: different parasites, same rules?

Trends Parasitol 2011 May 21;27(5):197-203. Epub 2011 Feb 21.

Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087881PMC
May 2011

Trypanosoma brucei brucei: endocytic recycling is important for mouse infectivity.

Exp Parasitol 2011 Apr 20;127(4):777-83. Epub 2011 Jan 20.

Department of Pathology, Tennis Court Road, University of Cambridge, Cambridge CB2 1QP, UK.

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April 2011

Transmission stages dominate trypanosome within-host dynamics during chronic infections.

Cell Host Microbe 2011 Apr;9(4):310-8

Centre for Immunity, Infection, and Evolution, Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094754PMC
April 2011

Frame-dragging vortexes and tidal tendexes attached to colliding black holes: visualizing the curvature of spacetime.

Phys Rev Lett 2011 Apr 11;106(15):151101. Epub 2011 Apr 11.

Center for Radiophysics and Space Research, Cornell University, Ithaca, New York 14853, USA.

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April 2011

Controlling and coordinating development in vector-transmitted parasites.

Authors:
Keith R Matthews

Science 2011 Mar;331(6021):1149-53

Centre for Immunity, Infection, and Evolution, Institute for Immunology and Infection Research, Ashworth Laboratories, School of Biological Sciences, King's Buildings, University of Edinburgh, Edinburgh EH9 3JT, UK.

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March 2011

Attention-deficit/hyperactivity disorder and Williams syndrome: shared behavioral and neuropsychological profiles.

J Clin Exp Neuropsychol 2011 Jan 9;33(1):147-56. Epub 2010 Aug 9.

Department of Psychology, University of Strathclyde, Glasgow, UK.

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January 2011

Developmental regulation and extracellular release of a VSG expression-site-associated gene product from Trypanosoma brucei bloodstream forms.

J Cell Sci 2010 Oct 7;123(Pt 19):3401-11. Epub 2010 Sep 7.

Centre for Immunity, Infection and Evolution, Institute of Immunology and Infection Research, School of Biological Sciences, Kings' Buildings, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, UK.

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October 2010

New discoveries in the transmission biology of sleeping sickness parasites: applying the basics.

J Mol Med (Berl) 2010 Sep 5;88(9):865-71. Epub 2010 Jun 5.

Centre for Immunity, Infection and Evolution, Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Kings Buildings, West Mains Road, Edinburgh, EH9 3JT, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921060PMC
September 2010

The silicon trypanosome.

Parasitology 2010 Aug 6;137(9):1333-41. Epub 2010 May 6.

Department of Pediatrics, Center for Liver, Digestive and Metabolic Diseases, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.

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August 2010

Functional characterisation and drug target validation of a mitotic kinesin-13 in Trypanosoma brucei.

PLoS Pathog 2010 Aug 19;6(8):e1001050. Epub 2010 Aug 19.

Department of Biological Sciences, University of Hull, Hull, UK.

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http://dx.doi.org/10.1371/journal.ppat.1001050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924347PMC
August 2010

A novel phosphatase cascade regulates differentiation in Trypanosoma brucei via a glycosomal signaling pathway.

Genes Dev 2010 Jun;24(12):1306-16

Centre for Immunity, Infection, and Evolution, Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885665PMC
June 2010

Meta-analysis and imputation refines the association of 15q25 with smoking quantity.

Authors:
Jason Z Liu Federica Tozzi Dawn M Waterworth Sreekumar G Pillai Pierandrea Muglia Lefkos Middleton Wade Berrettini Christopher W Knouff Xin Yuan Gérard Waeber Peter Vollenweider Martin Preisig Nicholas J Wareham Jing Hua Zhao Ruth J F Loos Inês Barroso Kay-Tee Khaw Scott Grundy Philip Barter Robert Mahley Antero Kesaniemi Ruth McPherson John B Vincent John Strauss James L Kennedy Anne Farmer Peter McGuffin Richard Day Keith Matthews Per Bakke Amund Gulsvik Susanne Lucae Marcus Ising Tanja Brueckl Sonja Horstmann H-Erich Wichmann Rajesh Rawal Norbert Dahmen Claudia Lamina Ozren Polasek Lina Zgaga Jennifer Huffman Susan Campbell Jaspal Kooner John C Chambers Mary Susan Burnett Joseph M Devaney Augusto D Pichard Kenneth M Kent Lowell Satler Joseph M Lindsay Ron Waksman Stephen Epstein James F Wilson Sarah H Wild Harry Campbell Veronique Vitart Muredach P Reilly Mingyao Li Liming Qu Robert Wilensky William Matthai Hakon H Hakonarson Daniel J Rader Andre Franke Michael Wittig Arne Schäfer Manuela Uda Antonio Terracciano Xiangjun Xiao Fabio Busonero Paul Scheet David Schlessinger David St Clair Dan Rujescu Gonçalo R Abecasis Hans Jörgen Grabe Alexander Teumer Henry Völzke Astrid Petersmann Ulrich John Igor Rudan Caroline Hayward Alan F Wright Ivana Kolcic Benjamin J Wright John R Thompson Anthony J Balmforth Alistair S Hall Nilesh J Samani Carl A Anderson Tariq Ahmad Christopher G Mathew Miles Parkes Jack Satsangi Mark Caulfield Patricia B Munroe Martin Farrall Anna Dominiczak Jane Worthington Wendy Thomson Steve Eyre Anne Barton Vincent Mooser Clyde Francks Jonathan Marchini

Nat Genet 2010 May 25;42(5):436-40. Epub 2010 Apr 25.

Department of Statistics, University of Oxford, Oxford, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612983PMC
May 2010

The trypanosome Pumilio-domain protein PUF7 associates with a nuclear cyclophilin and is involved in ribosomal RNA maturation.

FEBS Lett 2010 Mar 12;584(6):1156-62. Epub 2010 Feb 12.

Zentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), DKFZ-ZMBH Alliance, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.febslet.2010.02.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855960PMC
March 2010

Cell-cycle synchronisation of bloodstream forms of Trypanosoma brucei using Vybrant DyeCycle Violet-based sorting.

Mol Biochem Parasitol 2010 Jan 1;169(1):59-62. Epub 2009 Sep 1.

Centre for Immunity, Infection and Evolution, Institute of Immunology and Infection Research, University of Edinburgh, United Kingdom.

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http://dx.doi.org/10.1016/j.molbiopara.2009.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855956PMC
January 2010

Genome-wide expression profiling of in vivo-derived bloodstream parasite stages and dynamic analysis of mRNA alterations during synchronous differentiation in Trypanosoma brucei.

BMC Genomics 2009 Sep 11;10:427. Epub 2009 Sep 11.

Centre for Immunity, Infection and Evolution, Institute of Immunology and Infection Research, School of Biological Sciences, King's Buildings, University of Edinburgh, Edinburgh, UK.

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http://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2164-10-427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753553PMC
September 2009

A surface transporter family conveys the trypanosome differentiation signal.

Nature 2009 May;459(7244):213-7

Centre for Immunity, Infection and Evolution, Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, UK.

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http://dx.doi.org/10.1038/nature07997DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685892PMC
May 2009

Differential trypanosome surface coat regulation by a CCCH protein that co-associates with procyclin mRNA cis-elements.

PLoS Pathog 2009 Feb 27;5(2):e1000317. Epub 2009 Feb 27.

Centre for Immunology, Infection and Evolution, Institute of Immunology and Infection Research, School of Biological Sciences, Ashworth Laboratories, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1371/journal.ppat.1000317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642730PMC
February 2009