Keith M Kerr

Keith M Kerr

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Keith M Kerr

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Correlation of ROS1 Immunohistochemistry With Fusion Status Determined by Fluorescence In Situ Hybridization.

Arch Pathol Lab Med 2019 Sep 11. Epub 2019 Sep 11.

From Roche Molecular Solutions, Pleasanton, California (Dr Huang, Mr Smith, Dr Le, Mr Liu, Dr Ordinario, Dr Manohar, Mr Lee, Mr Rajamani, Mr Truong, Dr Jing Li, Ms Choi, Dr Jingchuan Li, Dr Pati, Ms Hanlon Newell, Mr Pate, and Dr Menzl); Institute of Pathology, University Hospital Basel, Basel, Switzerland (Dr Bubendorf); Institute for Pathology, University Hospital, Cologne, Germany (Dr Buettner); the Department of Pathology, Aberdeen University Medical School & Aberdeen Royal Infirmary, Foresterhill, Aberdeen, United Kingdom (Dr Kerr); Laboratorio de Dianas Terapeuticas, HM Hospitales, Spain (Dr Lopez-Rios); Center of Predictive Molecular Medicine, CeSIMeT, University of Chieti-Pescara, Italy (Dr Marchetti); Pfizer Oncology, International Developed Markets, Berlin, Germany (Ms Marondel); the Department of Histopathology, Royal Brompton and Harefield Hospitals, and National Heart and Lung Division, Imperial College, London, United Kingdom (Dr Nicholson); the Pathology Department, Istanbul University, Cerrahpassa Medical Faculty, Istanbul, Turkey (Dr Öz); CORE, Antwerp University, and the Department of Pathology, Antwerp University Hospital, Antwerp, Belgium (Mr Pauwels); the Department of Biopathology, Centre Jean Perrin & INSERM U240 IMoST and Université Clermont Auvergne, Clermont-Ferrand, France (Dr Penault-Llorca); Operative Unit of Pathology, AUSL della Romagna, Hospital S. Maria delle Croci, Ravenna, Italy (Dr Rossi); and the Department of Pathology, VU University Medical Center, Amsterdam, the Netherlands (Dr Thunnissen).

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http://dx.doi.org/10.5858/arpa.2019-0085-OADOI Listing
September 2019

Redefining Treatment Paradigms in First-line Advanced Non-Small-Cell Lung Cancer.

Clin Cancer Res 2019 Aug 25;25(16):4881-4887. Epub 2019 Mar 25.

Airway Research Center North in the German Center for Lung Research (DZL), Grosshansdorf, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-1894DOI Listing
August 2019

Comparing and contrasting predictive biomarkers for immunotherapy and targeted therapy of NSCLC.

Nat Rev Clin Oncol 2019 06;16(6):341-355

Department of Pathology, Aberdeen University Medical School, Aberdeen Royal Infirmary, Aberdeen, UK.

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http://dx.doi.org/10.1038/s41571-019-0173-9DOI Listing
June 2019

Defining aggressive or early progressing nononcogene-addicted non-small-cell lung cancer: a separate disease entity?

Future Oncol 2019 Apr 13;15(12):1363-1383. Epub 2019 Feb 13.

Boehringer Ingelheim Pharma GmbH & Co, KG, Germany & Institute of Pharmacology, Johannes Gutenberg-University Mainz, Germany.

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http://dx.doi.org/10.2217/fon-2018-0948DOI Listing
April 2019

The PD-L1 Immunohistochemistry Biomarker: Two Steps Forward, One Step Back?

Authors:
Keith M Kerr

J Thorac Oncol 2018 03;13(3):291-294

Aberdeen University Medical School and Aberdeen Royal Infirmary, Aberdeen, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15560864183008
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http://dx.doi.org/10.1016/j.jtho.2018.01.020DOI Listing
March 2018

Hypersensitivity Pneumonitis A Perspective From Members of the Pulmonary Pathology Society.

Arch Pathol Lab Med 2018 Jan 14;142(1):120-126. Epub 2017 Jun 14.

From the Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas (Drs Miller, Barrios, Cagle, and Ge); the Department of Pathology, University of Texas Medical Branch, Galveston (Dr Allen); the Department of Pathology, Mount Sinai Medical Center, New York, New York (Dr Beasley); the Department of Histopathology, Cork University Hospital, Cork, Ireland (Dr Burke); the Department of Pathology, University of São Paulo, São Paulo, Brazil (Dr Capelozzi); the Department of Pathology, Massachusetts General Hospital, Boston (Drs Hariri, Mark, and Mino-Kenudson); the Department of Pathology, Aberdeen University School of Medicine, Aberdeen, United Kingdom (Dr Kerr); the Department of Laboratory Medicine and Pathology, Mayo Clinic, Jacksonville, Florida (Dr Khoor); the Department of Laboratory Medicine and Pathology, Mayo Clinic, Scottsdale, Arizona (Drs Larsen and Smith); the Department of Pathology, National Defense Medical College, Tokorozawa, Japan (Dr Matsubara); the Department of Pathology, Vanderbilt University Medical Center, Nashville, Tennessee (Dr Mehrad); the Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois (Dr Raparia); the Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota (Dr Roden); the Department of Pathology, St Vincent's Pathology, Fitzroy, Australia (Dr Russell); the Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania (Dr Schneider); and the Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts (Dr Sholl).

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http://dx.doi.org/10.5858/arpa.2017-0138-SADOI Listing
January 2018

PD-1 blockade in advanced NSCLC: A focus on pembrolizumab.

Cancer Treat Rev 2018 Jan 23;62:39-49. Epub 2017 Oct 23.

Department of Oncology, University Hospital Zürich, Rämistrasse 100, 8091 Zürich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.ctrv.2017.10.002DOI Listing
January 2018

Programmed Death-Ligand 1 Immunohistochemistry Testing: A Review of Analytical Assays and Clinical Implementation in Non-Small-Cell Lung Cancer.

J Clin Oncol 2017 Dec 20;35(34):3867-3876. Epub 2017 Oct 20.

Reinhard Büttner, University Hospital Cologne, Cologne; Manfred Dietel, Charité Universitätsmedizin Berlin, Berlin, Germany; John R. Gosney, Royal Liverpool University Hospital, Liverpool; Andrew C. Wotherspoon, Royal Marsden Hospital, London; Keith M. Kerr, Aberdeen University Medical School and Aberdeen Royal Infirmary, Aberdeen, Scotland, United Kingdom; Birgit Guldhammer Skov, Copenhagen University Hospital, Copenhagen, Denmark; Julien Adam, Gustave Roussy Cancer Center, Villejuif; Frédérique Penault-Llorca, Jean Perrin Comprehensive Cancer Center, Clermont-Ferrand, France; Noriko Motoi, National Cancer Center Hospital, Tokyo, Japan; Kenneth J. Bloom, Human Longevity, San Diego, CA; John W. Longshore, Carolinas Pathology Group, Charlotte, NC; Fernando López-Ríos, Hospital Universitario HM Sanchinarro, Madrid, Spain; Giuseppe Viale, University of Milan, Milan, Italy; and Ming-Sound Tsao, University Health Network, Princess Margaret Cancer Centre and University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1200/JCO.2017.74.7642DOI Listing
December 2017

Liquid Biopsy in Lung Cancer: A Perspective From Members of the Pulmonary Pathology Society.

Arch Pathol Lab Med 2016 Aug 19;140(8):825-9. Epub 2016 May 19.

From the Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts (Drs Sholl and Vivero); the Department of Pathology, University of Colorado Cancer Center, Denver (Dr Aisner); the Department of Pathology, The University of Texas Medical Branch, Galveston (Dr Allen); the Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, New York (Dr Beasley); the Department of Pathology, Weill Cornell Medical College, New York, New York, and the Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas (Dr Cagle); the Department of Pathology, University of Sao Paulo Medical School, Sao Paulo, Brazil (Dr Capelozzi); the Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania (Dr Dacic); the Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston (Drs Hariri and Mino-Kenudson); the Department of Pathology, Aberdeen University Medical School and Aberdeen Royal Infirmary, Foresterhill, Aberdeen, Scotland, United Kingdom (Dr Kerr); the Department of Biopathology, Centre Léon Bérard, Lyon, France, and J Fourier University-INSERM U 823-Institut A Bonniot, Grenoble, France (Dr Lantuejoul); the Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois (Dr Raparia); the Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York (Dr Rekhtman); the Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston (Dr Roy-Chowdhuri); the Department of Pathology, VU Medical Center, Amsterdam, the Netherlands (Dr Thunnissen); the Department of Pathology, University Health Network/Princess Margaret Cancer Centre and University of Toronto, Toronto, Ontario, Canada (Dr Tsao); and the Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Nagoya, Japan (Dr Yatabe).

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http://dx.doi.org/10.5858/arpa.2016-0163-SADOI Listing
August 2016

Programmed Death Ligand-1 Immunohistochemistry: Friend or Foe?

Arch Pathol Lab Med 2016 Apr 12;140(4):326-31. Epub 2016 Jan 12.

From the Department of Pathology, Aberdeen University School of Medicine, Aberdeen Royal Infirmary, Aberdeen, Scotland, United Kingdom (Dr Kerr); and.

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http://dx.doi.org/10.5858/arpa.2015-0522-SADOI Listing
April 2016

Biomarker Testing in Lung Carcinoma Cytology Specimens: A Perspective From Members of the Pulmonary Pathology Society.

Arch Pathol Lab Med 2016 Apr 15. Epub 2016 Apr 15.

From the Department of Pathology, University of Texas MD Anderson Cancer Center, Houston (Dr Roy-Chowdhuri); the Department of Pathology, University of Colorado Cancer Center, Denver (Dr Aisner); the Department of Pathology, University of Texas Medical Branch, Galveston (Dr Allen); the Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, New York (Dr Beasley); the Department of Pathology, Weill Cornell Medical College, New York (Drs Borczuk and Cagle); the Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas (Dr Cagle); the Department of Pathology, University of Sao Paulo Medical School, Sao Paulo, Brazil (Dr Capelozzi); the Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania (Dr Dacic); the Department of Pathology, University Health Network, Princess Margaret Cancer Centre, and the University of Toronto, Toronto, Ontario, Canada (Drs da Cunha Santos and Tsao); the Department of Pathology, Massachusetts General Hospital, and Harvard Medical School, Boston (Drs Hariri and Mino-Kenudson); the Department of Pathology, Aberdeen University Medical School, and Aberdeen Royal Infirmary, Foresterhill, Aberdeen, Scotland, United Kingdom (Dr Kerr); the Department of Biopathology, Centre Léon Bérard, Lyon, and J Fourier University, Institut National de la Santé et de la Recherche Médicale-Institut Albert Bonniot, Grenoble, France (Dr Lantuejoul); the Department of Pathology, New York University, New York (Dr Moreira); the Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois (Dr Raparia); the Department of Pathology, Memorial Sloan Kettering Cancer Center, New York (Dr Rekhtman); the Department of Pathology, Brigham and Women's Hospital, and Harvard Medical School, Boston (Drs Sholl and Vivero); the Department of Pathology, VU University Medical Center, Amsterdam, the Netherlands (Dr Thunnissen); and the Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Nagoya, Japan (Dr Yatabe).

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http://dx.doi.org/10.5858/arpa.2016-0091-SADOI Listing
April 2016

Non-Small Cell Lung Cancer, PD-L1, and the Pathologist.

Arch Pathol Lab Med 2016 Mar;140(3):249-54

From the Department of Pathology, Aberdeen University School of Medicine (Dr Kerr), and the Department of Oncology (Dr Nicolson), Aberdeen Royal Infirmary, Aberdeen, United Kingdom.

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http://dx.doi.org/10.5858/arpa.2015-0303-SADOI Listing
March 2016

Programmed Death-Ligand 1 Immunohistochemistry in Lung Cancer: In what state is this art?

J Thorac Oncol 2015 Jul;10(7):985-9

*Department of Pathology, Aberdeen University Medical School, Aberdeen Royal Infirmary, Aberdeen, United Kingdom; †Department of Pathology, University Health Network-Princess Margaret Cancer Centre, University of Toronto, Toronto, Canada; ‡Department of Histopathology, Royal Brompton and Harefield Hospitals NHS Foundation Trust, London, United Kingdom; §Department of Pathology and Molecular Diagnostics, Aichi Cancer Centre, Nagoya, Japan; ‖Department of Pathology, University of Texas MD Anderson Cancer Centre, Houston, Texas; and ¶Division of Medical Oncology, Department of Pathology, University of Colorado Denver, Aurora, Colorado.

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http://dx.doi.org/10.1097/JTO.0000000000000526DOI Listing
July 2015

EGFR mutation testing practices within the Asia Pacific region: results of a multicenter diagnostic survey.

J Thorac Oncol 2015 Mar;10(3):438-45

*Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Nagoya, Japan; †Department of Pathology, Aberdeen University Medical School, Aberdeen, United Kingdom; ‡KalGen Laboratory, Stem-cell and Cancer Institute (SCI), Jakarta, Indonesia; §School of Medicine, Monash University Malaysia & Sime Darby Medical Center, Kuala Lumpur, Malaysia; ‖Center for Gene and Protein Research, Hanoi Medical University, Hanoi, Vietnam; ¶Department of Pathology, Fudan University Shanghai Cancer Center; Institute of Pathology, Fudan University, Shanghai, China; #Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; **Research and Biotechnology Division, St. Luke's Medical Center, Quezon City & COS-CENSER, De La Salle University, Manila, Philippines; ††Department of Pathology, National Cancer Center, Goyang-si, Gyeonggi-do, Korea; ‡‡Department of Pathology, Singapore General Hospital, Singapore, Singapore; §§Chulalongkorn GenePRO Center, Chulalongkorn Hospital, Bangkok, Thailand; ‖‖Seoul National University Bundang Hospital, Seoul, Korea; ¶¶Department of Respiratory Medicine, Saitama Medical University, Saitama, Japan; ##Peking Union Medical College Hospital, Beijing, China; ***Istituto Nazionale per lo Studio e la Cura dei Tumori "Fondazione Giovanni Pascale" - IRCCS, Naples, Italy; †††Division of Hematology/Oncology, Innovative Cancer Medicine Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; ‡‡‡Clinical Genomic Medicine/Thoracic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan; §§§Department of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; ‖‖‖University of Melbourne, Melbourne, VIC, Australia; ¶¶¶Sun Yat-Sen University Cancer Center, Guangzhou, China; ###Personalised Healthcare, AstraZeneca, Macclesfield, United Kingdom; ****Clinical Science Division, Astr

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http://dx.doi.org/10.1097/JTO.0000000000000422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342317PMC
March 2015

Lungscape: resected non-small-cell lung cancer outcome by clinical and pathological parameters.

J Thorac Oncol 2014 Nov;9(11):1675-84

*Centre Hospitalier Universitaire de Vaud, Lausanne, Switzerland; †Division of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland; ‡Frontier Science Foundation-Hellas & University of Athens, Athens, Greece; §Aberdeen Royal Infirmary, Aberdeen, United Kingdom; ‖Institute for Pathology, University Hospital Basel, Basel, Switzerland; ¶Department of Oncology, University Hospital, Aarhus, Denmark; #Department of Medical Oncology, St. James's Hospital, Dublin, Ireland; **Medical University of Gdansk, Gdansk, Poland; ††University Hospital KU Leuven, Leuven, Belgium; ‡‡Vall d'Hebron University Hospital, Barcelona, Spain; §§Center of Predictive Molecular Medicine, University Foundation, Chieti, Italy; ‖‖Shanghai Lung Cancer Center, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People's Republic of China; ¶¶VU University Medical Center, Amsterdam, Netherlands; ##Maastricht University Medical Centre, Maastricht, Netherlands; ***Manchester University and The Christie National Health Services Foundation Trust, Manchester, United Kingdom; †††Netherlands Cancer Institute, Amsterdam, Netherlands; ‡‡‡Department of Medicine, University of Valencia and Department of Medical Oncology, General University Hospital of Valencia, Valencia, Spain; §§§Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Badalona, Spain; and ‖‖‖Clinic of Oncology, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1097/JTO.0000000000000320DOI Listing
November 2014

Multicenter immunohistochemical ALK-testing of non-small-cell lung cancer shows high concordance after harmonization of techniques and interpretation criteria.

J Thorac Oncol 2014 Nov;9(11):1685-92

*Institute of Pathology, Charité BERLIN, Berlin, Germany; †Institute of Pathology, University of Heidelberg, Heidelberg, Germany; ‡Department of Pathology, Aberdeen University Medical School, Aberdeen, United Kingdom; §Department of Pathology and Cytology, Karolinska University Hospital, Solna, Stockholm, Sweden; ‖Department of Pathology, University Hospital Cologne, Cologne, Germany; ¶Laboratorio de Dianas Terapeuticas, Hospital Universitario Sanchinarro, Madrid, Spain; #Institute of Pathology, Klinikum Großhadern Ludwig-Maximilians-Universität, Munich, Germany; **Institute of Pathology, UZ ANTWERPEN, Edegem, Belgium; ††Institute of Pathology, Klinikum rechts der Isar, TU, Munich, Germany; ‡‡Institute of Pathology, University Hospital Carl Gustav Carus, Dresden, Germany; §§Institute of Pathology, Universitätsspital Basel, Basel, Germany; ‖‖Institute of Pathology, HSK Dr.-Horst-Schmidt-Kliniken GmbH, Wiesbaden, Germany; ¶¶Institute of Pathology, Universitäts Spital Zürich, Zurich, Switzerland; ##Institute of Pathology, Centre Jean Perrin, Clermont-Ferrand, France; ***Patologisk Institut, Århus Universitetshospital, Århus, Denmark; †††Pathology-Berlin, Bioptisches Institut Gemeinschaftspraxis für Pathologie, Berlin, Germany.

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http://dx.doi.org/10.1097/JTO.0000000000000332DOI Listing
November 2014

Calcified pulmonary chondromas in Carney's triad.

Thorax 2014 Oct 18;69(10):969-70. Epub 2013 Nov 18.

Department of Respiratory Medicine, Aberdeen Royal Infirmary, Aberdeen, UK.

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http://dx.doi.org/10.1136/thoraxjnl-2013-203829DOI Listing
October 2014

Prevalence and clinical outcomes for patients with ALK-positive resected stage I to III adenocarcinoma: results from the European Thoracic Oncology Platform Lungscape Project.

J Clin Oncol 2014 Sep 28;32(25):2780-7. Epub 2014 Jul 28.

Fiona H. Blackhall and Daisuke Nonaka, Manchester University and The Christie National Health Services Foundation Trust, Manchester; Keith M. Kerr, Aberdeen University Medical School, Aberdeen Royal Infirmary, Aberdeen, United Kingdom; Solange Peters and Igor Letovanec, Centre Hospitalier Universitaire Vaudois, Lausanne; Lukas Bubendorf and Spasenija Savic, Institute for Pathology, University Hospital Basel, Basel; Alex Soltermann and Rolf A. Stahel, University Hospital Zurich, Zurich, Switzerland; Urania Dafni, Frontier Science Foundation-Hellas and University of Athens, Athens, Greece; Henrik Hager, University Hospital, Aarhus, Denmark; Kenneth J. O'Byrne, St James's Hospital, Dublin, Ireland; Christoph Dooms, University Hospital KU Leuven, Leuven, Belgium; Aleksandra Sejda, Medical University of Gdansk, Gdansk, Poland; Javier Hernández-Losa, Vall d'Hebron University Hospital, Barcelona; Miguel Martorell, Universitat de Valencia and Hospital General Universitario de Valencia, Valencia; Rafael Rosell, Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Badalona, Spain; Antonio Marchetti, Center of Predictive Molecular Medicine, University Foundation, Chieti, Italy; Qiang Tan, Shanghai Lung Cancer Center, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People's Republic of China; Erik Thunnissen, VU University Medical Clinic Center; Jeroen de Jong, Netherlands Cancer Institute, Amsterdam; Ernst-Jan M. Speel, Maastricht University Medical Centre, Maastricht, the Netherlands; and Richard Cheney, Roswell Park Cancer Institute, Buffalo, NY.

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http://dx.doi.org/10.1200/JCO.2013.54.5921DOI Listing
September 2014

Reproducibility of histopathological diagnosis in poorly differentiated NSCLC: an international multiobserver study.

J Thorac Oncol 2014 Sep;9(9):1354-62

Departments of *Pathology and ††††Epidemiology and Biostatistics, VU University Medical Centre, Amsterdam, The Netherlands; †Department of Pathology, Faculty of Medicine, Tsukuba, Japan; ‡Rutgers New Jersey Medical School, Newark, New Jersey; §Department of Pathology, Mount Sinai Medical Center, New York, New York; ‖Elisabeth Brambilla, CHU Albert Michallon, Institut de Biologie, Département d'Anatomie et Cytologie Pathologiques, Grenoble Cedex, France; ¶Brigham and Women's Hospital, Boston, Massachusetts; #Department of Pathology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea; **Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania; ††Piedmont Pathology Associates, Hickory, North Carolina, and University of North Carolina, Chapel Hill, North Carolina; ‡‡Department of Medicine and Pathology, University of Colorado Cancer Center, Aurora, Colorado; §§Division of Pathology, The Cancer Institute, Japanese Foundation Cancer Research, Tokyo, Japan; ‖Department of Pathology, Aberdeen Royal Infirmary, Aberdeen, United Kingdom; ¶¶Department of Pathology, CHU A Michallon, INSERM U 823-Institut A Bonniot-University J Fourier, Grenoble, France; ##Department of Pathology, Cancer Center Hospital, Tsukuba, Japan; ***Department of Pathology, Institute of Basic Medical Sciences, University of Tsukuba, Tsukuba, Japan; †††Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York; ‡‡‡Department of Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale Tumori, and Università degli Studi of Milan, Milan, Italy; §§§Institut für Pathologie, Jena, Germany; ‖‖‖Duke University Medical Center, Durham, North Carolina; ¶¶¶University of Texas MD Anderson Cancer Center, Houston, Texas; ###Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Nagoya, Japan; ****Department of Oncology and Radiothe

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http://dx.doi.org/10.1097/JTO.0000000000000264DOI Listing
September 2014

Relationship between EGFR expression, EGFR mutation status, and the efficacy of chemotherapy plus cetuximab in FLEX study patients with advanced non-small-cell lung cancer.

J Thorac Oncol 2014 May;9(5):717-24

*Department of Medical Oncology, Institut de Cancerologie de l'Ouest, Centre René Gauducheau, Saint-Herblain, France; †Department of Medicine I, Medical University of Vienna, Vienna, Austria; ‡HOPE Directorate, St James's Hospital, Dublin, Ireland; §Department of Pathology, Aberdeen Royal Infirmary, Aberdeen, United Kingdom; ‖Institute of Pathology, University of Witten/Herdecke and HELIOS Hospital Wuppertal, Wuppertal, Germany; ¶Global Biostatistics, #Biomarker Technologies & Operations, and **Translational Innovation Platform Oncology, Merck KGaA, Darmstadt, Germany; and ††University Health Network, Department of Oncology and Hematology, Princess Margaret Cancer Centre, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1097/JTO.0000000000000141DOI Listing
May 2014

ALK testing in non-small cell lung carcinoma: what now?

Authors:
Keith M Kerr

J Thorac Oncol 2014 May;9(5):593-5

Department of Pathology, Aberdeen University School of Medicine, Aberdeen, United Kingdom.

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http://dx.doi.org/10.1097/JTO.0000000000000171DOI Listing
May 2014

BAI3, CDX2 and VIL1: a panel of three antibodies to distinguish small cell from large cell neuroendocrine lung carcinomas.

Histopathology 2014 Mar 25;64(4):547-56. Epub 2013 Nov 25.

Department of Pathology, Dow International Medical College, Karachi, Pakistan; Department of Pathology, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK; Divisions of Reproduction and Metabolic and Vascular Health, Warwick Medical School, Coventry, UK.

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http://dx.doi.org/10.1111/his.12278DOI Listing
March 2014

The UK Lung Screen (UKLS): demographic profile of first 88,897 approaches provides recommendations for population screening.

Cancer Prev Res (Phila) 2014 Mar 17;7(3):362-71. Epub 2014 Jan 17.

Roy Castle Lung Cancer Research Programme, The University of Liverpool Cancer Research Centre, Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, The University of Liverpool, Roy Castle Building, 200 London Road, Liverpool L3 9TA, United Kingdom.

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http://dx.doi.org/10.1158/1940-6207.CAPR-13-0206DOI Listing
March 2014

In compressed lung tissue microscopic sections of adenocarcinoma in situ may mimic papillary adenocarcinoma.

Arch Pathol Lab Med 2013 Dec;137(12):1792-7

From the Departments of Pathology (Drs Thunnissen and Beliën), Radiology (Dr Lely), and Surgery (Dr Hartemink), VU University Medical Center, Amsterdam, the Netherlands; the Department of Pathology, Aberdeen Royal Infirmary, Aberdeen University Medical School, Aberdeen, Scotland (Dr Kerr); the Department of Pathology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea (Dr Chung); the Department of Pathology, Fox Chase Cancer Center, Philadelphia, Pennsylvania (Dr Flieder); the Department of Pathology, Institute of Basic Medical Sciences, University of Tsukuba, Tsukuba, Japan (Dr Noguchi); the Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Nagoya, Japan (Dr Yatabe); the Department of Pathology, University Health Network-Princess Margaret Hospital and University of Toronto, Toronto, Ontario, Canada (Drs Hwang and Tsao); and the Department of Pathology, Symbiant/Medical Center Alkmaar, Alkmaar, the Netherlands (Dr Meijer-Jorna).

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http://dx.doi.org/10.5858/arpa.2012-0613-SADOI Listing
December 2013

Serpin b3 is associated with poor survival after chemotherapy and is a potential novel predictive biomarker in advanced non-small-cell lung cancer.

J Thorac Oncol 2013 Dec;8(12):1502-9

*School of Medicine and Dentistry, University of Aberdeen, Foresterhill Healthcare Campus, Foresterhill, Aberdeen, Scotland, United Kingdom; and Departments of †Oncology and ‡Pathology Aberdeen Royal Infirmary, Foresterhill Healthcare Campus, Foresterhill, Aberdeen, Scotland, United Kingdom.

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http://dx.doi.org/10.1097/JTO.0000000000000016DOI Listing
December 2013

Clinical relevance of the new IASLC/ERS/ATS adenocarcinoma classification.

Authors:
Keith M Kerr

J Clin Pathol 2013 Oct 6;66(10):832-8. Epub 2013 Apr 6.

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http://dx.doi.org/10.1136/jclinpath-2013-201519DOI Listing
October 2013

Prognostic factors in resected lung carcinomas.

EJC Suppl 2013 Sep;11(2):137-49

Aberdeen University Medical School, Department of Oncology, Aberdeen Royal Infirmary, Aberdeen, UK.

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http://dx.doi.org/10.1016/j.ejcsup.2013.07.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041316PMC
September 2013

Classification of lung cancer: proposals for change?

Authors:
Keith M Kerr

Arch Pathol Lab Med 2012 Oct;136(10):1190-3

Department of Pathology, Aberdeen University Medical School, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, Scotland, UK.

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http://dx.doi.org/10.5858/arpa.2012-0240-SADOI Listing
October 2012

Personalized medicine for lung cancer: new challenges for pathology.

Authors:
Keith M Kerr

Histopathology 2012 Mar 14;60(4):531-46. Epub 2011 Sep 14.

Aberdeen University Medical School, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, UK.

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http://dx.doi.org/10.1111/j.1365-2559.2011.03854.xDOI Listing
March 2012

DNA methylation changes in atypical adenomatous hyperplasia, adenocarcinoma in situ, and lung adenocarcinoma.

PLoS One 2011 23;6(6):e21443. Epub 2011 Jun 23.

Department of Surgery, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0021443PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121768PMC
November 2011

Revolution in lung cancer: new challenges for the surgical pathologist.

Arch Pathol Lab Med 2011 Jan;135(1):110-6

Department of Pathology and Laboratory Medicine, 6565 Fannin Street, The Methodist Hospital, Houston, Texas 77030, USA.

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January 2011

How to investigate a patient with suspected interstitial lung disease.

BMJ 2010 Jun 9;340:c2843. Epub 2010 Jun 9.

Department of Respiratory Medicine, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZN.

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June 2010

Quantitative analysis of tumor in bronchial biopsy specimens.

J Thorac Oncol 2010 Apr;5(4):448-52

Department of Pathology, Aberdeen Royal Infirmary and Aberdeen University Medical School, Aberdeen, United Kingdom.

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April 2010

Subtyping of undifferentiated non-small cell carcinomas in bronchial biopsy specimens.

J Thorac Oncol 2010 Apr;5(4):442-7

Department of Pathology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, Scotland, UK.

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April 2010

Closed pleural biopsy to diagnose mesothelioma: dead or alive?

Lung Cancer 2009 Sep 13;65(3):388-9. Epub 2009 Jun 13.

Department of Respiratory Medicine, Aberdeen Royal Infirmary, Aberdeen, UK.

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http://dx.doi.org/10.1016/j.lungcan.2009.05.005DOI Listing
September 2009

Sarcoidosis.

BMJ 2009 Aug 28;339:b3206. Epub 2009 Aug 28.

Department of Respiratory Medicine, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZN.

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August 2009

Pathologist and molecular biologist, ever the twain shall meet?

Authors:
Keith M Kerr

Lung Cancer 2009 Feb 22;63(2):161-3. Epub 2008 Nov 22.

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February 2009

Pulmonary adenocarcinomas: classification and reporting.

Authors:
Keith M Kerr

Histopathology 2009 Jan;54(1):12-27

Department of Pathology, Aberdeen University Medical School, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, UK.

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January 2009

Cutaneous penile and perianal Crohn's disease treated with a combination of medical and surgical interventions.

Australas J Dermatol 2008 Feb;49(1):21-4

Department of Dermatology, Aberdeen Royal Infirmary, Fosterhill, Aberdeen, UK.

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February 2008

The role of DNA methylation in the development and progression of lung adenocarcinoma.

Dis Markers 2007 ;23(1-2):5-30

Department of Pathology, Aberdeen Royal Infirmary, Link Building, Foresterhill, Aberdeen, AB25 2ZN, UK.

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May 2007

Spontaneous dissection of an anomalous systemic artery in the lung during pregnancy: a rare cause of hemoptysis.

Ann Thorac Surg 2006 Aug;82(2):725-6

Department of Cardiothoracic Surgery, Aberdeen Royal Infirmary, Aberdeen, United Kingdom.

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August 2006

Tumor transcriptome reveals the predictive and prognostic impact of lysosomal protease inhibitors in non-small-cell lung cancer.

J Clin Oncol 2006 Apr 20;24(11):1729-44. Epub 2006 Mar 20.

Oncology Research Group, Department of Medicine and Therapeutics, Institute of Medical Sciences, School of Medicine, University of Aberdeen, Aberdeen, nited Kingdom.

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April 2006

Gene expression profiling in non-small cell lung cancer: from molecular mechanisms to clinical application.

Clin Cancer Res 2004 May;10(10):3237-48

Department of Oncology, Aberdeen and Oncology Research Group, Department of Medicine and Therapeutics, University of Aberdeen, Aberdeen, United Kingdom.

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May 2004

Evaluation of NQO1 gene expression and variant allele in human NSCLC tumors and matched normal lung tissue.

Int J Oncol 2002 Nov;21(5):1119-24

School of Pharmacy, University of Wisconsin-Madison, 777 Highland Avenue, Madison, WI 53706-1515, USA.

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November 2002

Changing trends in incidence of lung cancer by histologic type in Scotland.

Int J Cancer 2002 Nov;102(2):179-83

ARC Epidemiology Unit, Stopford Building, University of Manchester, Oxford Road, Manchester M13 9PT, UK.

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November 2002