Keith L Knutson

Keith L Knutson

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Keith L Knutson

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The evolving clinical landscape for dendritic cell vaccines and cancer immunotherapy.

Immunotherapy 2019 02;11(2):75-79

Department of Immunology, Mayo Clinic Florida, 4500 San Pablo Road S, Jacksonville, FL 32224, USA.

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http://dx.doi.org/10.2217/imt-2018-0129DOI Listing
February 2019

Cancer immunotherapy beyond immune checkpoint inhibitors.

J Hematol Oncol 2018 01 12;11(1). Epub 2018 Jan 12.

Department of Hematology and Oncology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.

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http://dx.doi.org/10.1186/s13045-017-0552-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767051PMC
January 2018

Downregulation of TAP1 and TAP2 in early stage breast cancer.

PLoS One 2017 1;12(11):e0187323. Epub 2017 Nov 1.

Department of Immunology, Mayo Clinic, Jacksonville, Florida, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0187323PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706630PMC
December 2017

Multivalent bi-specific nanobioconjugate engager for targeted cancer immunotherapy.

Nat Nanotechnol 2017 08 1;12(8):763-769. Epub 2017 May 1.

Department of Neurosurgery, Mayo Clinic College of Medicine, 4500 San Pablo Road, Jacksonville, Florida 32224, USA.

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http://www.nature.com/doifinder/10.1038/nnano.2017.69
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http://dx.doi.org/10.1038/nnano.2017.69DOI Listing
August 2017

Cytokine and neuropeptide levels are associated with pain relief in patients with chronically painful total knee arthroplasty: a pilot study.

BMC Musculoskelet Disord 2017 01 14;18(1):17. Epub 2017 Jan 14.

Department of Immunology, Mayo Clinic College of Medicine, 200 1st St SW, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1186/s12891-016-1375-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237514PMC
January 2017

Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer.

Authors:
Shalaka S Hampras Lara E Sucheston-Campbell Rikki Cannioto Jenny Chang-Claude Francesmary Modugno Thilo Dörk Peter Hillemanns Leah Preus Keith L Knutson Paul K Wallace Chi-Chen Hong Grace Friel Warren Davis Mary Nesline Celeste L Pearce Linda E Kelemen Marc T Goodman Elisa V Bandera Kathryn L Terry Nils Schoof Kevin H Eng Alyssa Clay Prashant K Singh Janine M Joseph Katja K H Aben Hoda Anton-Culver Natalia Antonenkova Helen Baker Yukie Bean Matthias W Beckmann Maria Bisogna Line Bjorge Natalia Bogdanova Louise A Brinton Angela Brooks-Wilson Fiona Bruinsma Ralf Butzow Ian G Campbell Karen Carty Linda S Cook Daniel W Cramer Cezary Cybulski Agnieszka Dansonka-Mieszkowska Joe Dennis Evelyn Despierre Ed Dicks Jennifer A Doherty Andreas du Bois Matthias Dürst Doug Easton Diana Eccles Robert P Edwards Arif B Ekici Peter A Fasching Brooke L Fridley Yu-Tang Gao Aleksandra Gentry-Maharaj Graham G Giles Rosalind Glasspool Jacek Gronwald Patricia Harrington Philipp Harter Hanis Nazihah Hasmad Alexander Hein Florian Heitz Michelle A T Hildebrandt Claus Hogdall Estrid Hogdall Satoyo Hosono Edwin S Iversen Anna Jakubowska Allan Jensen Bu-Tian Ji Beth Y Karlan Melissa Kellar Joseph L Kelley Lambertus A Kiemeney Rüdiger Klapdor Nonna Kolomeyevskaya Camilla Krakstad Susanne K Kjaer Bridget Kruszka Jolanta Kupryjanczyk Diether Lambrechts Sandrina Lambrechts Nhu D Le Alice W Lee Shashikant Lele Arto Leminen Jenny Lester Douglas A Levine Dong Liang Jolanta Lissowska Song Liu Karen Lu Jan Lubinski Lene Lundvall Leon F A G Massuger Keitaro Matsuo Valeria McGuire John R McLaughlin Ian McNeish Usha Menon Joanna Moes-Sosnowska Steven A Narod Lotte Nedergaard Heli Nevanlinna Stefan Nickels Sara H Olson Irene Orlow Rachel Palmieri Weber James Paul Tanja Pejovic Liisa M Pelttari Barbara Perkins Jenny Permuth-Wey Malcolm C Pike Joanna Plisiecka-Halasa Elizabeth M Poole Harvey A Risch Mary Anne Rossing Joseph H Rothstein Anja Rudolph Ingo B Runnebaum Iwona K Rzepecka Helga B Salvesen Eva Schernhammer Kristina Schmitt Ira Schwaab Xiao-Ou Shu Yurii B Shvetsov Nadeem Siddiqui Weiva Sieh Honglin Song Melissa C Southey Ingvild L Tangen Soo-Hwang Teo Pamela J Thompson Agnieszka Timorek Ya-Yu Tsai Shelley S Tworoger Jonathan Tyrer Anna M van Altena Ignace Vergote Robert A Vierkant Christine Walsh Shan Wang-Gohrke Nicolas Wentzensen Alice S Whittemore Kristine G Wicklund Lynne R Wilkens Anna H Wu Xifeng Wu Yin-Ling Woo Hannah Yang Wei Zheng Argyrios Ziogas Simon A Gayther Susan J Ramus Thomas A Sellers Joellen M Schildkraut Catherine M Phelan Andrew Berchuck Georgia Chenevix-Trench Julie M Cunningham Paul P Pharoah Roberta B Ness Kunle Odunsi Ellen L Goode Kirsten B Moysich

Oncotarget 2016 10;7(43):69097-69110

Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York, USA.

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http://dx.doi.org/10.18632/oncotarget.10215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340115PMC
October 2016

Retraction Note: Targeted immune therapy of ovarian cancer.

Cancer Metastasis Rev 2016 09;35(3):489

Department of Immunology, Mayo Clinic, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1007/s10555-016-9627-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118946PMC
September 2016

Cancer vaccines in the new era of cancer immunotherapy.

Vaccine 2015 Dec 2;33(51):7376. Epub 2015 Oct 2.

Department of Breast Surgical Oncology, MD Anderson Cancer Center, Houston, TX, United States.

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http://dx.doi.org/10.1016/j.vaccine.2015.09.086DOI Listing
December 2015

Plasma immune analytes in patients with epithelial ovarian cancer.

Cytokine 2015 May 3;73(1):108-13. Epub 2015 Mar 3.

Vaccine and Gene Therapy Institute, Port Saint Lucie, FL, United States; Department of Immunology, Mayo Clinic, Rochester, MN, United States.

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http://dx.doi.org/10.1016/j.cyto.2015.01.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380743PMC
May 2015

Tumor-infiltrating dendritic cells in cancer pathogenesis.

J Immunol 2015 Apr;194(7):2985-91

Department of Immunology, Mayo Clinic, Rochester, MN 55906; and Cancer Vaccines and Immune Therapies Program, Vaccine and Gene Therapy Institute, Port St. Lucie, FL 34987

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http://dx.doi.org/10.4049/jimmunol.1403134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369768PMC
April 2015

Targeted immune therapy of ovarian cancer.

Cancer Metastasis Rev 2015 Mar;34(1):53-74

Cancer Vaccines and Immune Therapies Program, The Vaccine and Gene Therapy Institute of Florida, 9801 SW Discovery Way, Port St. Lucie, FL, 34949, USA,

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http://dx.doi.org/10.1007/s10555-014-9540-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369418PMC
March 2015

Variation in NF-κB signaling pathways and survival in invasive epithelial ovarian cancer.

Cancer Epidemiol Biomarkers Prev 2014 Jul 16;23(7):1421-7. Epub 2014 Apr 16.

Health Sciences Research, Division of Epidemiology;

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http://dx.doi.org/10.1158/1055-9965.EPI-13-0962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082406PMC
July 2014

Tumor hypomethylation at 6p21.3 associates with longer time to recurrence of high-grade serous epithelial ovarian cancer.

Cancer Res 2014 Jun 11;74(11):3084-91. Epub 2014 Apr 11.

Authors' Affiliations: Departments of Health Sciences Research, Medical Oncology, Obstetrics and Gynecology, and Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota; Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles; Department of Research, Illumina, San Diego, California; Departments of Cancer Biology and Biostatistics, University of Kansas Medical Center, Kansas City, Kansas; and Vaccine and Gene Therapy Institute of Florida, Port St. Lucie, Florida

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http://dx.doi.org/10.1158/0008-5472.CAN-13-3198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054691PMC
June 2014

Accumulation of memory precursor CD8 T cells in regressing tumors following combination therapy with vaccine and anti-PD-1 antibody.

Cancer Res 2014 Jun 11;74(11):2974-85. Epub 2014 Apr 11.

Authors' Affiliations: Cancer Vaccines and Immune Therapies Program, Vaccine & Gene Therapy Institute of Florida, Port St. Lucie, Florida; and Departments of Immunology and Oncology, Mayo Clinic, Rochester, MinnesotaAuthors' Affiliations: Cancer Vaccines and Immune Therapies Program, Vaccine & Gene Therapy Institute of Florida, Port St. Lucie, Florida; and Departments of Immunology and Oncology, Mayo Clinic, Rochester, Minnesota

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-13-2564DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313351PMC
June 2014

Large-scale evaluation of common variation in regulatory T cell-related genes and ovarian cancer outcome.

Authors:
Bridget Charbonneau Kirsten B Moysich Kimberly R Kalli Ann L Oberg Robert A Vierkant Zachary C Fogarty Matthew S Block Matthew J Maurer Krista M Goergen Brooke L Fridley Julie M Cunningham David N Rider Claudia Preston Lynn C Hartmann Kate Lawrenson Chen Wang Jonathan Tyrer Honglin Song Anna deFazio Sharon E Johnatty Jennifer A Doherty Catherine M Phelan Thomas A Sellers Starr M Ramirez Allison F Vitonis Kathryn L Terry David Van Den Berg Malcolm C Pike Anna H Wu Andrew Berchuck Aleksandra Gentry-Maharaj Susan J Ramus Brenda Diergaarde Howard Shen Allan Jensen Janusz Menkiszak Cezary Cybulski Jan Lubiłski Argyrios Ziogas Joseph H Rothstein Valerie McGuire Weiva Sieh Jenny Lester Christine Walsh Ignace Vergote Sandrina Lambrechts Evelyn Despierre Montserrat Garcia-Closas Hannah Yang Louise A Brinton Beata Spiewankiewicz Iwona K Rzepecka Agnieszka Dansonka-Mieszkowska Petra Seibold Anja Rudolph Lisa E Paddock Irene Orlow Lene Lundvall Sara H Olson Claus K Hogdall Ira Schwaab Andreas du Bois Philipp Harter James M Flanagan Robert Brown James Paul Arif B Ekici Matthias W Beckmann Alexander Hein Diana Eccles Galina Lurie Laura E Hays Yukie T Bean Tanja Pejovic Marc T Goodman Ian Campbell Peter A Fasching Gottfried Konecny Stanley B Kaye Florian Heitz Estrid Hogdall Elisa V Bandera Jenny Chang-Claude Jolanta Kupryjanczyk Nicolas Wentzensen Diether Lambrechts Beth Y Karlan Alice S Whittemore Hoda Anton Culver Jacek Gronwald Douglas A Levine Susanne K Kjaer Usha Menon Joellen M Schildkraut Celeste Leigh Pearce Daniel W Cramer Mary Anne Rossing Georgia Chenevix-Trench Paul D P Pharoah Simon A Gayther Roberta B Ness Kunle Odunsi Lara E Sucheston Keith L Knutson Ellen L Goode

Cancer Immunol Res 2014 Apr 27;2(4):332-40. Epub 2014 Jan 27.

Authors' Affiliations: The University of Texas School of Public Health, Houston, Texas.

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http://dx.doi.org/10.1158/2326-6066.CIR-13-0136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000890PMC
April 2014

Risk of ovarian cancer and the NF-κB pathway: genetic association with IL1A and TNFSF10.

Authors:
Bridget Charbonneau Matthew S Block William R Bamlet Robert A Vierkant Kimberly R Kalli Zachary Fogarty David N Rider Thomas A Sellers Shelley S Tworoger Elizabeth Poole Harvey A Risch Helga B Salvesen Lambertus A Kiemeney Laura Baglietto Graham G Giles Gianluca Severi Britton Trabert Nicolas Wentzensen Georgia Chenevix-Trench Alice S Whittemore Weiva Sieh Jenny Chang-Claude Elisa V Bandera Irene Orlow Kathryn Terry Marc T Goodman Pamela J Thompson Linda S Cook Mary Anne Rossing Roberta B Ness Steven A Narod Jolanta Kupryjanczyk Karen Lu Ralf Butzow Thilo Dörk Tanja Pejovic Ian Campbell Nhu D Le Clareann H Bunker Natalia Bogdanova Ingo B Runnebaum Diana Eccles James Paul Anna H Wu Simon A Gayther Estrid Hogdall Florian Heitz Stanley B Kaye Beth Y Karlan Hoda Anton-Culver Jacek Gronwald Claus K Hogdall Diether Lambrechts Peter A Fasching Usha Menon Joellen Schildkraut Celeste Leigh Pearce Douglas A Levine Susanne Kruger Kjaer Daniel Cramer James M Flanagan Catherine M Phelan Robert Brown Leon F A G Massuger Honglin Song Jennifer A Doherty Camilla Krakstad Dong Liang Kunle Odunsi Andrew Berchuck Allan Jensen Jan Lubinski Heli Nevanlinna Yukie T Bean Galina Lurie Argyrios Ziogas Christine Walsh Evelyn Despierre Louise Brinton Alexander Hein Anja Rudolph Agnieszka Dansonka-Mieszkowska Sara H Olson Philipp Harter Jonathan Tyrer Allison F Vitonis Angela Brooks-Wilson Katja K Aben Malcolm C Pike Susan J Ramus Elisabeth Wik Cezary Cybulski Jie Lin Lara Sucheston Robert Edwards Valerie McGuire Jenny Lester Andreas du Bois Lene Lundvall Shan Wang-Gohrke Lukasz M Szafron Sandrina Lambrechts Hannah Yang Matthias W Beckmann Liisa M Pelttari Anne M Van Altena David van den Berg Mari K Halle Aleksandra Gentry-Maharaj Ira Schwaab Urmila Chandran Janusz Menkiszak Arif B Ekici Lynne R Wilkens Arto Leminen Francesmary Modugno Grace Friel Joseph H Rothstein Ignace Vergote Montserrat Garcia-Closas Michelle A T Hildebrandt Piotr Sobiczewski Linda E Kelemen Paul D P Pharoah Kirsten Moysich Keith L Knutson Julie M Cunningham Brooke L Fridley Ellen L Goode

Cancer Res 2014 Feb 22;74(3):852-61. Epub 2013 Nov 22.

Authors' Affiliations: Departments of Health Sciences Research, Division of Epidemiology, Medical Oncology, Health Sciences Research, Division of Biomedical Statistics and Informatics, Immunology, and Laboratory Medicine and Pathology, Division of Experimental Pathology, Mayo Clinic, Rochester, Minnesota; Department of Cancer Epidemiology, Division of Population Sciences, Moffitt Cancer Center, Tampa, Florida; Channing Division of Network Medicine, Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital, Harvard Medical School; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts; Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, Connecticut; Department of Clinical Science, University of Bergen; Departments of Gynecology and Obstetrics, and Pathology, Haukeland University Hospital, Bergen, Norway; Departments for Health Evidence, Urology, and Gynaecology, Radboud University Medical Centre, Nijmegen; Comprehensive Cancer Center The Netherlands, Utrecht, the Netherlands; Cancer Epidemiology Centre, The Cancer Council Victoria; Centre for Molecular, Environmental, Genetic and Analytical Epidemiology, Department of Pathology, and Sir Peter MacCallum Department of Oncology, University of Melbourne; Department of Epidemiology and Preventive Medicine, Monash University; Peter MacCallum Cancer Institute; Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria; Cancer Division, Queensland Institute of Medical Research, Herston, Queensland, Australia; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland; Department of Health Research and Policy, Division of Epidemiology, Stanford University School of Medicine, Palo Alto; Samuel Oschin Comprehensive Cancer Institute; Women's Cancer Program, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center; Department of Preventive Medicine, Keck School of Medicine, University of Sout

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946482PMC
February 2014

The immune system in the pathogenesis of ovarian cancer.

Crit Rev Immunol 2013 ;33(2):137-64

Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940260PMC
http://dx.doi.org/10.1615/critrevimmunol.2013006813DOI Listing
October 2013

Utility of progranulin and serum leukocyte protease inhibitor as diagnostic and prognostic biomarkers in ovarian cancer.

Cancer Epidemiol Biomarkers Prev 2013 Oct 22;22(10):1730-5. Epub 2013 Jul 22.

Authors' Affiliations: Mayo Medical School, Biomedical Statistics and Informatics, and Departments of Medical Oncology and Immunology, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1158/1055-9965.EPI-12-1368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839679PMC
October 2013

Toward understanding the genetics of regulatory T cells in ovarian cancer.

Oncoimmunology 2013 Jun 16;2(6):e24535. Epub 2013 Apr 16.

Department of Health Sciences Research; Mayo Clinic; Rochester, MN, USA.

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http://dx.doi.org/10.4161/onci.24535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716752PMC
June 2013

Enzymatic discovery of a HER-2/neu epitope that generates cross-reactive T cells.

J Immunol 2013 Jan 23;190(1):479-88. Epub 2012 Nov 23.

Department of Immunology, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.4049/jimmunol.1201264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529812PMC
January 2013

A profile of immune response to herpesvirus is associated with radiographic joint damage in rheumatoid arthritis.

Arthritis Res Ther 2012 Jan 31;14(1):R24. Epub 2012 Jan 31.

Division of Rheumatology, Department of Medicine, College of Medicine, Mayo Clinic; 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1186/ar3706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392817PMC
January 2012

TGFbeta/TNF(alpha)-mediated epithelial-mesenchymal transition generates breast cancer stem cells with a claudin-low phenotype.

Cancer Res 2011 Jul 9;71(13):4707-19. Epub 2011 May 9.

Department of Immunology and Oncology, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-4554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129359PMC
July 2011

Genomics of the NF-κB signaling pathway: hypothesized role in ovarian cancer.

Cancer Causes Control 2011 May 27;22(5):785-801. Epub 2011 Feb 27.

Department of Health Sciences Research, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA.

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http://link.springer.com/10.1007/s10552-011-9745-4
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http://dx.doi.org/10.1007/s10552-011-9745-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119514PMC
May 2011

Immunity and immune suppression in human ovarian cancer.

Immunotherapy 2011 Apr;3(4):539-56

Department of Immunology, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.2217/imt.11.20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147144PMC
April 2011

Antibodies in cancer immunotherapy.

Cancer Biomark 2010 ;6(5-6):291-305

Department of Immunology, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.3233/CBM-2009-0141DOI Listing
January 2011

GM-CSF is one of the main breast tumor-derived soluble factors involved in the differentiation of CD11b-Gr1- bone marrow progenitor cells into myeloid-derived suppressor cells.

Breast Cancer Res Treat 2010 Aug 8;123(1):39-49. Epub 2009 Nov 8.

Department of Microbiology & Immunology, Virginia Commonwealth University School of Medicine, Massey Cancer Center, Box 980035, 401 College St, Richmond, VA 23298, USA.

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http://dx.doi.org/10.1007/s10549-009-0622-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095485PMC
August 2010

HLA-A2-restricted T-cell epitopes specific for prostatic acid phosphatase.

Cancer Immunol Immunother 2010 Jun 6;59(6):943-53. Epub 2010 Feb 6.

Department of Medicine, University of Wisconsin, Madison, WI 53792, USA.

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http://dx.doi.org/10.1007/s00262-010-0820-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038205PMC
June 2010

Analysis of complex biomarkers for human immune-mediated disorders based on cytokine responsiveness of peripheral blood cells.

J Immunol 2010 Jun 21;184(12):7297-304. Epub 2010 May 21.

Division of Rheumatology, Department of Medicine, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.4049/jimmunol.0904180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882518PMC
June 2010

Intraepithelial effector (CD3+)/regulatory (FoxP3+) T-cell ratio predicts a clinical outcome of human colon carcinoma.

Gastroenterology 2009 Oct 3;137(4):1270-9. Epub 2009 Jul 3.

Miles and Shirley Fiterman Digestive Disease Center, Division of Gastroenterology & Hepatology, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1053/j.gastro.2009.06.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873775PMC
October 2009

Therapeutic vaccines for malignant brain tumors.

Biologics 2008 Dec;2(4):753-61

Division of Transfusion Medicine;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727883PMC
http://dx.doi.org/10.2147/btt.s3197DOI Listing
December 2008

Signatures associated with rejection or recurrence in HER-2/neu-positive mammary tumors.

Cancer Res 2008 Apr;68(7):2436-46

Department of Microbiology and Immunology, Virginia Commonwealth University School of Medicine, Massey Cancer Center, Richmond, VA 23298, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-6822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478745PMC
April 2008

Folate receptor alpha as a tumor target in epithelial ovarian cancer.

Gynecol Oncol 2008 Mar 28;108(3):619-26. Epub 2008 Jan 28.

Division of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S009082580700932
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http://dx.doi.org/10.1016/j.ygyno.2007.11.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707764PMC
March 2008

The endogenous danger signal, crystalline uric acid, signals for enhanced antibody immunity.

Blood 2008 Feb 20;111(3):1472-9. Epub 2007 Nov 20.

Department of Immunology, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1182/blood-2007-10-117184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2214762PMC
February 2008

Augmented HER-2 specific immunity during treatment with trastuzumab and chemotherapy.

Clin Cancer Res 2007 Sep;13(17):5133-43

Department of Microbiology, College of Physicians and Surgeons, Columbia University, New York, NY 10027-6902, USA.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-07-0507DOI Listing
September 2007

Tumor immunoediting and immunosculpting pathways to cancer progression.

Semin Cancer Biol 2007 Aug 26;17(4):275-87. Epub 2007 Jun 26.

Department of Immunology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, United States.

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http://linkinghub.elsevier.com/retrieve/pii/S1044579X0700034
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http://dx.doi.org/10.1016/j.semcancer.2007.06.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742305PMC
August 2007

Renal hemodynamic, inflammatory, and apoptotic responses to lipopolysaccharide in HO-1-/- mice.

Am J Pathol 2007 Jun;170(6):1820-30

Division of Nephrology and Hypertension, Department of Pathology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899452PMC
http://dx.doi.org/10.2353/ajpath.2007.061093DOI Listing
June 2007

CD4 regulatory T cells in human cancer pathogenesis.

Cancer Immunol Immunother 2007 Mar 4;56(3):271-85. Epub 2006 Jul 4.

Department of Immunology, Mayo Clinic College of Medicine, Mayo Clinic, 342C Guggenheim, 200 First Street SW, Rochester, MN 55905, USA.

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http://link.springer.com/10.1007/s00262-006-0194-y
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http://dx.doi.org/10.1007/s00262-006-0194-yDOI Listing
March 2007

HER-2/neu antigen loss and relapse of mammary carcinoma are actively induced by T cell-mediated anti-tumor immune responses.

Eur J Immunol 2007 Mar;37(3):675-85

Department of Microbiology & Immunology , VCU School of Medicine, Massey Cancer Center, Richmond, VA 23298, USA.

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http://dx.doi.org/10.1002/eji.200636639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732067PMC
March 2007

Tumor antigen-specific T-cell expansion is greatly facilitated by in vivo priming.

Clin Cancer Res 2007 Mar;13(6):1883-91

Tumor Vaccine Group, Center for Translational Medicine in Women's Health, University of Washington, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-2083DOI Listing
March 2007

The tumor antigen repertoire identified in tumor-bearing neu transgenic mice predicts human tumor antigens.

Cancer Res 2006 Oct;66(19):9754-61

Tumor Vaccine Group, Center for Translational Medicine in Women's Health, University of Washington, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-1083DOI Listing
October 2006

T-cell immunity to the folate receptor alpha is prevalent in women with breast or ovarian cancer.

J Clin Oncol 2006 Sep 14;24(26):4254-61. Epub 2006 Aug 14.

Department of Immunology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

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http://ascopubs.org/doi/10.1200/JCO.2006.05.9311
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http://dx.doi.org/10.1200/JCO.2006.05.9311DOI Listing
September 2006

IL-2 immunotoxin therapy modulates tumor-associated regulatory T cells and leads to lasting immune-mediated rejection of breast cancers in neu-transgenic mice.

J Immunol 2006 Jul;177(1):84-91

Department of Immunology, Mayo Clinic College of Medicine, 342C Guggenheim, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.4049/jimmunol.177.1.84DOI Listing
July 2006

Strong-arming immune regulation: suppressing regulatory T-cell function to treat cancers.

Authors:
Keith L Knutson

Future Oncol 2006 Jun;2(3):379-89

Department of Immunology, Mayo Clinic College of Medicine, 342C Guggenheim, 200 First St. SW, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.2217/14796694.2.3.379DOI Listing
June 2006

Laboratory analysis of T-cell immunity.

Front Biosci 2006 May 1;11:1932-44. Epub 2006 May 1.

Department of Immunology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

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http://dx.doi.org/10.2741/1936DOI Listing
May 2006

Emergence of immune escape variant of mammary tumors that has distinct proteomic profile and a reduced ability to induce "danger signals".

Breast Cancer Res Treat 2006 Apr 7;96(3):233-41. Epub 2005 Oct 7.

Department of Microbiology and Immunology, Virginia Commonwealth University, Massey Cancer Center, Richmond, VA, 23298, USA.

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http://dx.doi.org/10.1007/s10549-005-9044-4DOI Listing
April 2006

Erratum to: Emergence of immune escape variant of mammary tumors that has distinct proteomic profile and a reduced ability to induce "danger signals".

Breast Cancer Res Treat 2006 Apr 16;96(3):243. Epub 2006 Mar 16.

Microbiology & Immunology, Virginia Commonwealth University, Massey Cancer Center, 401 N. College Street, 1-128, 980037, Richmond, VA, 23298-0037, USA.

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http://dx.doi.org/10.1007/s10549-006-9163-6DOI Listing
April 2006

Adoptive T cell therapy of solid cancers.

Cancer Immunol Immunother 2006 Jan 27;55(1):96-103. Epub 2005 Oct 27.

Mayo Clinic College of Medicine, 342D Guggenheim, 200 First St SW, Mayo Clinic, Rochester, MN 55905, USA.

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http://link.springer.com/10.1007/s00262-005-0706-1
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http://dx.doi.org/10.1007/s00262-005-0706-1DOI Listing
January 2006

Antitumor efficacy of CD137 ligation is maximized by the use of a CD137 single-chain Fv-expressing whole-cell tumor vaccine compared with CD137-specific monoclonal antibody infusion.

Mol Cancer Ther 2006 Jan;5(1):149-55

Department of Pathology, Center for Translational Medicine in Women's Health, University of Washington, Seattle, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-05-0206DOI Listing
January 2006

Peptide-based vaccines in breast cancer.

Breast Dis 2004 ;20:3-11

Tumor Vaccine Group, Oncology, University of Washington, Seattle, WA 98195-6527, USA.

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http://dx.doi.org/10.3233/bd-2004-20102DOI Listing
April 2005

HER-2/neu vaccines.

Cancer Chemother Biol Response Modif 2003 ;21:275-85

University of Washington, Seattle 98195-6527, USA.

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http://dx.doi.org/10.1016/s0921-4410(03)21013-9DOI Listing
September 2004

Humoral epitope-spreading following immunization with a HER-2/neu peptide based vaccine in cancer patients.

J Clin Immunol 2004 Sep;24(5):571-8

Tumor Vaccine Group, Division of Oncology, University of Washington, Seattle, Washington 98195-6527, USA.

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http://dx.doi.org/10.1023/B:JOCI.0000040928.67495.52DOI Listing
September 2004