Keith Johnson

Keith Johnson

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Social Engagement and Amyloid-β-Related Cognitive Decline in Cognitively Normal Older Adults.

Am J Geriatr Psychiatry 2019 Nov 10;27(11):1247-1256. Epub 2019 May 10.

Division of Geriatric Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jagp.2019.05.005DOI Listing
November 2019

Evaluation of Oxathiapiprolin for the Management of Sunflower Downy Mildew.

Plant Dis 2019 Oct 27;103(10):2498-2504. Epub 2019 Aug 27.

Department of Plant Pathology, North Dakota State University, Fargo, ND 58102.

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http://dx.doi.org/10.1094/PDIS-11-18-2045-REDOI Listing
October 2019

Synergism between fornix microstructure and beta amyloid accelerates memory decline in clinically normal older adults.

Neurobiol Aging 2019 09 16;81:38-46. Epub 2019 May 16.

Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732225PMC
September 2019

Evaluation of pharmacokinetic modeling strategies for in-vivo quantification of tau with the radiotracer [F]MK6240 in human subjects.

Eur J Nucl Med Mol Imaging 2019 Sep 22;46(10):2099-2111. Epub 2019 Jul 22.

Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1007/s00259-019-04419-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709592PMC
September 2019

Defining response to TNF-inhibitors in rheumatoid arthritis: the negative impact of anti-TNF cycling and the need for a personalized medicine approach to identify primary non-responders.

Clin Rheumatol 2019 Sep 13. Epub 2019 Sep 13.

Scipher Medicine Corp, 260 Charles Street, Suite 301, Waltham, MA, 02453, USA.

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http://dx.doi.org/10.1007/s10067-019-04684-1DOI Listing
September 2019

Multi-Modal Signatures of Tau Pathology, Neuronal Fiber Integrity, and Functional Connectivity in Traumatic Brain Injury.

J Neurotrauma 2019 Aug 1. Epub 2019 Aug 1.

1Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1089/neu.2018.6178DOI Listing
August 2019

Neuropathologic correlates of amyloid and dopamine transporter imaging in Lewy body disease.

Neurology 2019 Jul 26;93(5):e476-e484. Epub 2019 Jun 26.

From the Departments of Neurology (J.S., R.Y., K.A.J., T.G.-I., J.H.G., S.N.G.), Pathology (N.C., M.F.), and Radiology (S.K., A.S., K.A.J.), Massachusetts General Hospital, Boston.

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http://dx.doi.org/10.1212/WNL.0000000000007855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693430PMC
July 2019

The origin of the conductivity maximum in molten salts. III. Zinc halides.

J Chem Phys 2019 Jul;151(3):034507

Department of Chemistry and Biochemistry, University of Regina, Regina, Saskatchewan S4S 0A2, Canada.

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http://dx.doi.org/10.1063/1.5109138DOI Listing
July 2019

Associations between baseline amyloid, sex, and APOE on subsequent tau accumulation in cerebrospinal fluid.

Neurobiol Aging 2019 06 7;78:178-185. Epub 2019 Mar 7.

Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Harvard Medical School, Boston, MA, USA; Gordon Center for Medical Imaging, Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, USA; Department of Neurology, Cliniques Universitaires Saint-Luc, Brussels, Belgium.

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https://linkinghub.elsevier.com/retrieve/pii/S01974580193006
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http://dx.doi.org/10.1016/j.neurobiolaging.2019.02.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545139PMC
June 2019

Speaker-normalized sound representations in the human auditory cortex.

Nat Commun 2019 06 5;10(1):2465. Epub 2019 Jun 5.

Department of Neurological Surgery, University of California, San Francisco, 675 Nelson Rising Lane, San Francisco, California, 94158, USA.

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http://dx.doi.org/10.1038/s41467-019-10365-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549175PMC
June 2019

Visual cognition in non-amnestic Alzheimer's disease: Relations to tau, amyloid, and cortical atrophy.

Neuroimage Clin 2019 4;23:101889. Epub 2019 Jun 4.

Frontotemporal Disorders Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.nicl.2019.101889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562373PMC
June 2019

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.

Cell Death Discov 2019 19;5:105. Epub 2019 Jun 19.

1Eppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198 USA.

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http://dx.doi.org/10.1038/s41420-019-0185-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584691PMC
June 2019

A longitudinal model for tau aggregation in Alzheimer's disease based on structural connectivity.

Inf Process Med Imaging 2019 22;11492:384-393. Epub 2019 May 22.

Department of Electrical and Computer Engineering, University of Massachusetts Lowell, Lowell, MA, USA.

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http://dx.doi.org/10.1007/978-3-030-20351-1_29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541421PMC
May 2019

PET imaging of tau protein targets: a methodology perspective.

Brain Imaging Behav 2019 Apr;13(2):333-344

Athinoula A. Martinos Center for Biomedical Research, Department of Radiology, Massachusetts General Hospital / Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1007/s11682-018-9847-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119534PMC
April 2019

Tired and lack focus? Insomnia increases distractibility.

J Health Psychol 2019 Apr 22:1359105319842927. Epub 2019 Apr 22.

1 CIRUS, Centre for Sleep and Chronobiology, Woolcock Institute of Medical Research, Sydney, NSW, Australia.

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http://dx.doi.org/10.1177/1359105319842927DOI Listing
April 2019

GRAPH CONVOLUTIONAL NEURAL NETWORKS FOR ALZHEIMER'S DISEASE CLASSIFICATION.

Proc IEEE Int Symp Biomed Imaging 2019 Apr 11;2019:414-417. Epub 2019 Jul 11.

Department of Electrical and Computer Engineering, University of Massachusetts Lowell, Lowell, MA.

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http://dx.doi.org/10.1109/ISBI.2019.8759531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641559PMC
April 2019

Global White Matter Diffusion Characteristics Predict Longitudinal Cognitive Change Independently of Amyloid Status in Clinically Normal Older Adults.

Cereb Cortex 2019 Mar;29(3):1251-1262

Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1093/cercor/bhy031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499008PMC
March 2019

Learnings about the complexity of extracellular tau aid development of a blood-based screen for Alzheimer's disease.

Alzheimers Dement 2019 Mar 9;15(3):487-496. Epub 2018 Nov 9.

Laboratory for Neurodegenerative Research, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, England. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476313PMC
March 2019

Nonlinear Distributional Mapping (NoDiM) for harmonization across amyloid-PET radiotracers.

Neuroimage 2019 02 17;186:446-454. Epub 2018 Nov 17.

Harvard Aging Brain Study, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10538119183209
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http://dx.doi.org/10.1016/j.neuroimage.2018.11.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338495PMC
February 2019

Tau Accumulation in Clinically Normal Older Adults Is Associated with Hippocampal Hyperactivity.

J Neurosci 2019 01 27;39(3):548-556. Epub 2018 Nov 27.

Harvard Aging Brain Study, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114.

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http://dx.doi.org/10.1523/JNEUROSCI.1397-18.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335746PMC
January 2019

Threshold regression to accommodate a censored covariate.

Biometrics 2018 12 22;74(4):1261-1270. Epub 2018 Jun 22.

Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, U.S.A.

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http://dx.doi.org/10.1111/biom.12922DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321791PMC
December 2018

Neurogenetic contributions to amyloid beta and tau spreading in the human cortex.

Nat Med 2018 12 29;24(12):1910-1918. Epub 2018 Oct 29.

Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://www.nature.com/articles/s41591-018-0206-4
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http://dx.doi.org/10.1038/s41591-018-0206-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518398PMC
December 2018

Correction: Association of anxiety with subcortical amyloidosis in cognitively normal older adults.

Mol Psychiatry 2018 Dec 11. Epub 2018 Dec 11.

Center for Alzheimer Research and Treatment, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1038/s41380-018-0323-yDOI Listing
December 2018

Regional tau pathology and loneliness in cognitively normal older adults.

Transl Psychiatry 2018 12 18;8(1):282. Epub 2018 Dec 18.

Department of Psychiatry, Division of Geriatric Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1038/s41398-018-0345-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299114PMC
December 2018

Flortaucipir tau PET imaging in semantic variant primary progressive aphasia.

J Neurol Neurosurg Psychiatry 2018 10 6;89(10):1024-1031. Epub 2017 Oct 6.

Frontotemporal Disorders Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, USA.

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http://dx.doi.org/10.1136/jnnp-2017-316409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964045PMC
October 2018

PET staging of amyloidosis using striatum.

Alzheimers Dement 2018 10 21;14(10):1281-1292. Epub 2018 May 21.

Department of Radiology, Massachusetts General Hospital, Harvard Medical School, and the Martinos Center for Biomedical Imaging, Charlestown, MA, USA; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.jalz.2018.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219621PMC
October 2018

Dedifferentiation of caudate functional connectivity and striatal dopamine transporter density predict memory change in normal aging.

Proc Natl Acad Sci U S A 2018 10 17;115(40):10160-10165. Epub 2018 Sep 17.

Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129.

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http://dx.doi.org/10.1073/pnas.1804641115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176586PMC
October 2018

The origin of the conductivity maximum vs. mixing ratio in pyridine/acetic acid and water/acetic acid.

J Chem Phys 2018 Sep;149(9):094505

Department of Chemistry and Biochemistry, University of Regina, Regina, Saskatchewan S4S 0A2, Canada.

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http://dx.doi.org/10.1063/1.5039623DOI Listing
September 2018

Amyloid-associated increases in longitudinal report of subjective cognitive complaints.

Alzheimers Dement (N Y) 2018 6;4:444-449. Epub 2018 Sep 6.

Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.trci.2018.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153378PMC
September 2018

Association of anxiety with subcortical amyloidosis in cognitively normal older adults.

Mol Psychiatry 2018 Aug 16. Epub 2018 Aug 16.

Center for Alzheimer Research and Treatment, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.

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http://www.nature.com/articles/s41380-018-0214-2
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http://dx.doi.org/10.1038/s41380-018-0214-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377864PMC
August 2018

Turtle Flexion Reflex Motor Patterns Show Windup, Mediated Partly by L-type Calcium Channels.

Front Neural Circuits 2017 31;11:83. Epub 2017 Oct 31.

Department of Biology, University of Oklahoma, Norman, OK, United States.

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http://dx.doi.org/10.3389/fncir.2017.00083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671496PMC
July 2018

Modeling the effect of palate shape on the articulatory-acoustics mapping.

J Acoust Soc Am 2018 07;144(1):EL71

University of California, Berkeley, Berkeley, California 94720, USA

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http://dx.doi.org/10.1121/1.5048043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033614PMC
July 2018

Longitudinal Association of Amyloid Beta and Anxious-Depressive Symptoms in Cognitively Normal Older Adults.

Am J Psychiatry 2018 06 12;175(6):530-537. Epub 2018 Jan 12.

From the Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston; the Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston; the Division of Geriatric Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Mass.; the Department of Neurology, Cliniques Universitaires Saint-Luc, Institute of Neurosciences, Université Catholique de Louvain, Brussels; the Department of Psychiatry, the Department of Neurology, and the Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston.

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http://dx.doi.org/10.1176/appi.ajp.2017.17040442DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988933PMC
June 2018

Encoding of Articulatory Kinematic Trajectories in Human Speech Sensorimotor Cortex.

Neuron 2018 06 17;98(5):1042-1054.e4. Epub 2018 May 17.

Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.04.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992088PMC
June 2018

How Do We Know when Single-Molecule Force Spectroscopy Really Tests Single Bonds?

Biophys J 2018 05;114(9):2032-2039

Department of Bioengineering, University of Washington, Seattle, Washington. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2018.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961468PMC
May 2018

Anosognosia for memory deficits in mild cognitive impairment: Insight into the neural mechanism using functional and molecular imaging.

Neuroimage Clin 2017 25;15:408-414. Epub 2017 May 25.

Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02115, USA; Athinoula A. Martinos Center for Biomedical Imaging and the Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02114, USA; Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.nicl.2017.05.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458095PMC
March 2018

Structural tract alterations predict downstream tau accumulation in amyloid-positive older individuals.

Nat Neurosci 2018 03 5;21(3):424-431. Epub 2018 Feb 5.

Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41593-018-0070-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857215PMC
March 2018

A Pixel-Encoder Retinal Ganglion Cell with Spatially Offset Excitatory and Inhibitory Receptive Fields.

Cell Rep 2018 02;22(6):1462-1472

Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Neuroscience, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Biomedical Engineering, Washington University School of Medicine, Saint Louis, MO 63110, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, Saint Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.01.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826572PMC
February 2018

Tau and amyloid β proteins distinctively associate to functional network changes in the aging brain.

Alzheimers Dement 2017 Nov 30;13(11):1261-1269. Epub 2017 Mar 30.

Gordon Center for Medical Imaging, Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Department of Neurology, Center for Alzheimer Research and Treatment, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.jalz.2017.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623176PMC
November 2017

Local processing in neurites of VGluT3-expressing amacrine cells differentially organizes visual information.

Elife 2017 10 12;6. Epub 2017 Oct 12.

Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, Saint Louis, United States.

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https://elifesciences.org/articles/31307
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http://dx.doi.org/10.7554/eLife.31307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653236PMC
October 2017

Early and late change on the preclinical Alzheimer's cognitive composite in clinically normal older individuals with elevated amyloid β.

Alzheimers Dement 2017 Sep 28;13(9):1004-1012. Epub 2017 Feb 28.

Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Department of Neurology, Center for Alzheimer Research and Treatment, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2017.01.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573651PMC
September 2017

The association between tau PET and retrospective cortical thinning in clinically normal elderly.

Neuroimage 2017 08 22;157:612-622. Epub 2017 May 22.

Department of Neurology, Massachusetts General Hospital, Harvard Medical School, and the Martinos Center for Biomedical Imaging, 149/10.008 13th Street, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1016/j.neuroimage.2017.05.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772972PMC
August 2017

Regional 18F-Fluorodeoxyglucose Hypometabolism is Associated with Higher Apathy Scores Over Time in Early Alzheimer Disease.

Am J Geriatr Psychiatry 2017 Jul 4;25(7):683-693. Epub 2017 Jan 4.

Center of Alzheimer Research and Treatment, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1016/j.jagp.2016.12.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906700PMC
July 2017

Hierarchical Organization of Tau and Amyloid Deposits in the Cerebral Cortex.

JAMA Neurol 2017 07;74(7):813-820

Gordon Center for Medical Imaging, Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts4Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts5Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamaneurol.2017.0263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710537PMC
July 2017

Functional network integrity presages cognitive decline in preclinical Alzheimer disease.

Neurology 2017 Jul 7;89(1):29-37. Epub 2017 Jun 7.

From the Florey Institutes of Neuroscience and Mental Health (R.F.B.), Melbourne; Melbourne School of Psychological Science (R.F.B.), University of Melbourne, Australia; Department of Neurology (R.F.B., A.P.S., K.V.P., B.J.H., G.M., D.M.R., K.A.J., R.A.S., J.P.C.), Athinoula A. Martinos Center for Biomedical Imaging (A.P.S., T.H., B.J.H., J.S., K.A.J.) and Gordon Center for Medical Imaging, Division of Nuclear Medicine and Molecular Imaging (J.S., K.A.J.), Department of Radiology, Massachusetts General Hospital; Harvard Medical School (R.F.B., A.P.S., T.H., K.V.P., B.J.H., G.M., D.M.R., K.A.J., R.A.S., J.P.C.); Center for Alzheimer Research and Treatment, Department of Neurology (K.V.P., G.M., D.M.R., K.A.J., R.A.S., J.P.C.), Brigham and Women's Hospital, Boston, MA: and Department of Psychiatry (E.E.S.), University of Texas Southwestern Medical Center, Dallas.

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http://dx.doi.org/10.1212/WNL.0000000000004059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496516PMC
July 2017

Neuroimaging markers associated with maintenance of optimal memory performance in late-life.

Neuropsychologia 2017 06 1;100:164-170. Epub 2017 May 1.

Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, MA, United States; Department of Neurology, Massachusetts General Hospital, Boston, MA, United States.

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http://dx.doi.org/10.1016/j.neuropsychologia.2017.04.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522601PMC
June 2017

Hippocampal hypometabolism in older adults with memory complaints and increased amyloid burden.

Neurology 2017 May 5;88(18):1759-1767. Epub 2017 Apr 5.

From the Department of Neurology (P.V., B.H., C.E.M., K.A.J., D.M.R., K.A.H., R.A.S.), Massachusetts General Hospital, Harvard Medical School, Boston; Athinoula A. Martinos Center for Biomedical Imaging (P.V., B.H., K.A.J., R.A.S.), Department of Psychiatry (P.V., B.H., K.A.J., R.A.S.), and Department of Radiology (B.H., K.A.J.), Division of Molecular Imaging and Nuclear Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown; Center for Alzheimer Research and Treatment (P.V., R.E.A., G.A.M., K.A.J., D.M.R., R.A.S.), Department of Neurology, Brigham and Women's Hospital, Harvard Medical School; and Berenson-Allen Center for Noninvasive Brain Stimulation and Division for Cognitive Neurology (A.P.-L.), Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1212/WNL.0000000000003889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409840PMC
May 2017

Memory self-awareness in the preclinical and prodromal stages of Alzheimer's disease.

Neuropsychologia 2017 05 3;99:343-349. Epub 2017 Apr 3.

Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02114, USA; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02114, USA; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02115, USA; Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.neuropsychologia.2017.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473166PMC
May 2017

The influence of demographic factors on subjective cognitive concerns and beta-amyloid.

Int Psychogeriatr 2017 04 11;29(4):645-652. Epub 2016 Oct 11.

Department of Neurology,Brigham and Women's Hospital,Center for Alzheimer Research and Treatment,Boston,MA,USA.

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http://dx.doi.org/10.1017/S1041610216001502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361739PMC
April 2017

Epicenters of dynamic connectivity in the adaptation of the ventral visual system.

Hum Brain Mapp 2017 04 28;38(4):1965-1976. Epub 2016 Dec 28.

Gordon Center For Medical Imaging, Department of Radiology, Division of Nuclear Medicine and Molecular Imaging, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/hbm.23497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342908PMC
April 2017

Association of In Vivo [18F]AV-1451 Tau PET Imaging Results With Cortical Atrophy and Symptoms in Typical and Atypical Alzheimer Disease.

JAMA Neurol 2017 04;74(4):427-436

Frontotemporal Disorders Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown2Alzheimer's Disease Research Center, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown4Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Charlestown.

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http://dx.doi.org/10.1001/jamaneurol.2016.5755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470368PMC
April 2017

Fluorodeoxyglucose metabolism associated with tau-amyloid interaction predicts memory decline.

Ann Neurol 2017 Apr 6;81(4):583-596. Epub 2017 Apr 6.

Department of Neurology, Massachusetts General Hospital, Harvard Medical School, and the Martinos Center for Biomedical Imaging, Charlestown, MA.

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http://dx.doi.org/10.1002/ana.24910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404378PMC
April 2017

Cued memory decline in biomarker-defined preclinical Alzheimer disease.

Neurology 2017 Apr 10;88(15):1431-1438. Epub 2017 Mar 10.

From the Center for Alzheimer Research and Treatment (K.V.P., D.M.R., R.E.A., K.A.J., R.A.S.), Department of Neurology, Brigham and Women's Hospital, Harvard Medical School; Department of Neurology (D.M.R., E.C.M., A.P.S., K.A.J., R.A.S.), Department of Psychiatry (Y.Q.), and Division of Nuclear Medicine and Molecular Imaging (K.A.J.), Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston; and Athinoula A. Martinos Center for Biomedical Imaging (A.P.S.), Massachusetts General Hospital, Charlestown.

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http://dx.doi.org/10.1212/WNL.0000000000003812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386436PMC
April 2017

Pharmacokinetic Evaluation of the Tau PET Radiotracer F-T807 (F-AV-1451) in Human Subjects.

J Nucl Med 2017 Mar 22;58(3):484-491. Epub 2016 Sep 22.

Gordon Center for Medical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts

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http://dx.doi.org/10.2967/jnumed.115.170910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334185PMC
March 2017

Case 1-2017. A 70-Year-Old Woman with Gradually Progressive Loss of Language.

N Engl J Med 2017 01;376(2):158-167

From the Department of Neurology, Northwestern Medicine, Chicago (M.-M.M.); and the Departments of Neurology (B.C.D., J.C.S., K.A.J.), Psychiatry (J.C.S.), Speech, Language, and Swallowing Disorders and Reading Disabilities (D.H.), Radiology (R.G.G., K.A.J.), and Pathology (M.P.F.), Massachusetts General Hospital, and the Departments of Neurology (B.C.D.), Psychiatry (J.C.S.), Radiology (R.G.G., K.A.J.), and Pathology (M.P.F.), Harvard Medical School - both in Boston.

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http://dx.doi.org/10.1056/NEJMcpc1613459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264551PMC
January 2017

Association of Higher Cortical Amyloid Burden With Loneliness in Cognitively Normal Older Adults.

JAMA Psychiatry 2016 Dec;73(12):1230-1237

Center for Alzheimer Research and Treatment, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts2Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts5Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston.

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http://dx.doi.org/10.1001/jamapsychiatry.2016.2657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5257284PMC
December 2016

Tau Positron Emission Tomographic Imaging in the Lewy Body Diseases.

JAMA Neurol 2016 Nov;73(11):1334-1341

Alzheimer's Disease Research Center, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown4Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Charlestown5Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston.

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http://dx.doi.org/10.1001/jamaneurol.2016.3338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287290PMC
November 2016

Palmitoylation of Desmoglein 2 Is a Regulator of Assembly Dynamics and Protein Turnover.

J Biol Chem 2016 Nov 4;291(48):24857-24865. Epub 2016 Oct 4.

From the Department of Oral Biology, College of Dentistry, University of Nebraska Medical Center, Lincoln, Nebraska 68583,

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http://dx.doi.org/10.1074/jbc.M116.739458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122758PMC
November 2016

Linear Regression with a Randomly Censored Covariate: Application to an Alzheimer's Study.

J R Stat Soc Ser C Appl Stat 2017 27;66(2):313-328. Epub 2016 Jun 27.

Harvard T.H. Chan School of Public Health, Boston, USA.

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http://dx.doi.org/10.1111/rssc.12164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319605PMC
June 2016

Multiple Imputation of a Randomly Censored Covariate Improves Logistic Regression Analysis.

J Appl Stat 2016 16;43(15):2886-2896. Epub 2016 Mar 16.

Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047523PMC
http://dx.doi.org/10.1080/02664763.2016.1155110DOI Listing
March 2016