Keith D Paulsen

Keith D Paulsen

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Keith D Paulsen

Publications by authors named "Keith D Paulsen"

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A Randomized Prospective Trial of Supine MRI-Guided Versus Wire-Localized Lumpectomy for Breast Cancer.

Ann Surg Oncol 2019 Oct 29;26(10):3099-3108. Epub 2019 Jul 29.

Department of Biomedical Data Science, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.

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http://dx.doi.org/10.1245/s10434-019-07531-4DOI Listing
October 2019

Quantitative subsurface spatial frequency-domain fluorescence imaging for enhanced glioma resection.

J Biophotonics 2019 May 20;12(5):e201800271. Epub 2019 Mar 20.

Princess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1002/jbio.201800271
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http://dx.doi.org/10.1002/jbio.201800271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470016PMC
May 2019

5-Aminolevulinic Acid-Induced Fluorescence in Focal Cortical Dysplasia: Report of 3 Cases.

Oper Neurosurg (Hagerstown) 2019 04;16(4):403-414

Section of Neurosurgery, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.

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http://dx.doi.org/10.1093/ons/opy116DOI Listing
April 2019

Phantom evaluations of low frequency MR elastography.

Phys Med Biol 2019 03 12;64(6):065010. Epub 2019 Mar 12.

Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, United States of America. Author to whom any correspondence should be addressed.

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http://dx.doi.org/10.1088/1361-6560/ab0290DOI Listing
March 2019

Quantification of Subdural Electrode Shift Between Initial Implantation, Postimplantation Computed Tomography, and Subsequent Resection Surgery.

Oper Neurosurg (Hagerstown) 2019 01;16(1):9-19

Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire.

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http://dx.doi.org/10.1093/ons/opy050DOI Listing
January 2019

Stereovision Co-Registration in Image-Guided Spinal Surgery: Accuracy Assessment Using Explanted Porcine Spines.

Oper Neurosurg (Hagerstown) 2018 12;15(6):686-691

Division of Neurosurgery, University of Vermont Medical Center, Burlington, Vermont.

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http://dx.doi.org/10.1093/ons/opy023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126994PMC
December 2018

Optimizing Glioma Detection Using an EGFR-Targeted Fluorescent Affibody.

Photochem Photobiol 2018 11 28;94(6):1167-1171. Epub 2018 Sep 28.

Thayer School of Engineering, Dartmouth College, Hanover, NH.

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http://dx.doi.org/10.1111/php.13003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234080PMC
November 2018

MR elastography at 1 Hz of gelatin phantoms using 3D or 4D acquisition.

J Magn Reson 2018 11 31;296:112-120. Epub 2018 Aug 31.

Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA; Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jmr.2018.08.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235749PMC
November 2018

Review of methods for intraoperative margin detection for breast conserving surgery.

J Biomed Opt 2018 10;23(10):1-19

Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, United States.

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http://dx.doi.org/10.1117/1.JBO.23.10.100901DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210801PMC
October 2018

Phantom evaluations of nonlinear inversion MR elastography.

Phys Med Biol 2018 07 19;63(14):145021. Epub 2018 Jul 19.

Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, United States of America.

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http://dx.doi.org/10.1088/1361-6560/aacb08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095192PMC
July 2018

Image Updating for Brain Shift Compensation During Resection.

Oper Neurosurg (Hagerstown) 2018 04;14(4):402-411

Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire.

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http://dx.doi.org/10.1093/ons/opx123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057506PMC
April 2018

Addressing Multipath Signal Corruption in Microwave Tomography and the Influence on System Design and Algorithm Development.

Open Access J Biomed Eng Biosci 2018 5;1(1). Epub 2018 Feb 5.

Thayer School of Engineering, Dartmouth College, USA.

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http://dx.doi.org/10.32474/OAJBEB.2018.01.000102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395052PMC
February 2018

Optimal wavelength selection for optical spectroscopy of hemoglobin and water within a simulated light-scattering tissue.

J Biomed Opt 2018 01;23(7):1-5

Tufts University, Department of Biomedical Engineering, Medford, Massachusetts, United States.

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http://dx.doi.org/10.1117/1.JBO.23.7.071202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820754PMC
January 2018

Addition of T2-guided optical tomography improves noncontrast breast magnetic resonance imaging diagnosis.

Breast Cancer Res 2017 Oct 24;19(1):117. Epub 2017 Oct 24.

Thayer School of Engineering, Dartmouth College, 14 Engineering Drive, Hanover, NH, 03755, USA.

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http://dx.doi.org/10.1186/s13058-017-0902-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655871PMC
October 2017

A numerical framework for interstitial fluid pressure imaging in poroelastic MRE.

PLoS One 2017 6;12(6):e0178521. Epub 2017 Jun 6.

Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0178521PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460821PMC
September 2017

Two-step inversion with a logarithmic transformation for microwave breast imaging.

Med Phys 2017 Aug 17;44(8):4239-4251. Epub 2017 Jul 17.

Thayer School of Engineering, Dartmouth College, Hanover, NH, USA.

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http://dx.doi.org/10.1002/mp.12384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553696PMC
August 2017

Fluorescence depth estimation from wide-field optical imaging data for guiding brain tumor resection: a multi-inclusion phantom study.

Biomed Opt Express 2017 Aug 14;8(8):3656-3670. Epub 2017 Jul 14.

Thayer School of Engineering, Dartmouth College, 14 Engineering Dr. Hanover, NH 03755, USA.

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http://dx.doi.org/10.1364/BOE.8.003656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560832PMC
August 2017

Electrical Characterization of Glycerin: Water Mixtures: Implications for Use as a Coupling Medium in Microwave Tomography.

IEEE Trans Microw Theory Tech 2017 May 31;65(5):1471-1478. Epub 2017 Jan 31.

Thayer School of Engineering at Dartmouth College, Hanover, NH 03755 USA.

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http://dx.doi.org/10.1109/TMTT.2016.2638423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428894PMC
May 2017

Multiobjective guided priors improve the accuracy of near-infrared spectral tomography for breast imaging.

J Biomed Opt 2016 09;21(9):90506

Dartmouth College, Thayer School of Engineering, Hanover, New Hampshire 03755, United States.

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http://dx.doi.org/10.1117/1.JBO.21.9.090506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034016PMC
September 2016

Microdose fluorescence imaging of ABY-029 on an operating microscope adapted by custom illumination and imaging modules.

Biomed Opt Express 2016 Sep 9;7(9):3280-3288. Epub 2016 Aug 9.

Center for Imaging Medicine, Thayer School of Engineering, Dartmouth College, 1 Medical Center Drive, Lebanon, NH 03756, USA; Department of Surgery, Geisel School of Medicine at Dartmouth, 1 Rope Ferry Road, Hanover, NH 03755, USA.

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http://dx.doi.org/10.1364/BOE.7.003280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030010PMC
September 2016

Mathematical model to interpret localized reflectance spectra measured in the presence of a strong fluorescence marker.

J Biomed Opt 2016 Jun;21(6):61004

Dartmouth College, Thayer School of Engineering, 14 Engineering Drive, Hanover, New Hampshire 03755, United StatesbDartmouth-Hitchcock Medical Center, Norris Cotton Cancer Center, 1 Medical Center Drive, Lebanon, New Hampshire 03756, United States.

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http://dx.doi.org/10.1117/1.JBO.21.6.061004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734982PMC
June 2016

Observation of direction-dependent mechanical properties in the human brain with multi-excitation MR elastography.

J Mech Behav Biomed Mater 2016 06 18;59:538-546. Epub 2016 Mar 18.

Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA; Department of Biomedical Engineering, University of Delaware, Newark, Delaware 19716, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jmbbm.2016.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860072PMC
June 2016

Wide-field quantitative imaging of tissue microstructure using sub-diffuse spatial frequency domain imaging.

Optica 2016 Jun 9;3(6):613-621. Epub 2016 Jun 9.

Thayer School of Engineering, Dartmouth College, 14 Engineering Drive, Hanover, New Hampshire 03755, USA; Norris Cotton Cancer Center, Dartmouth Hitchcock Medical Center, 1 Medical Center Drive, Lebanon, New Hampshire 03756, USA.

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http://dx.doi.org/10.1364/OPTICA.3.000613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989924PMC
June 2016

3D microwave tomography of the breast using prior anatomical information.

Med Phys 2016 Apr;43(4):1933

Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755; Department of Radiology, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire 03755; Norris Cotton Cancer Center, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756; and Advanced Surgical Center, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756.

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http://dx.doi.org/10.1118/1.4944592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808070PMC
April 2016

Intraoperative CT as a registration benchmark for intervertebral motion compensation in image-guided open spinal surgery.

Int J Comput Assist Radiol Surg 2015 Dec 21;10(12):2009-20. Epub 2015 Jul 21.

Geisel School of Medicine, Dartmouth College, Hanover, NH, 03755, USA.

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http://dx.doi.org/10.1007/s11548-015-1255-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734629PMC
December 2015

Improved sensitivity to fluorescence for cancer detection in wide-field image-guided neurosurgery.

Biomed Opt Express 2015 Dec 30;6(12):5063-74. Epub 2015 Nov 30.

Dept. Engineering Physics, Polytechnique Montreal, CP 6079, Succ. Centre-Ville, Montreal, QC, H3C 3A7, Canada ; Centre de Recherche du Centre Hospitalier de l'Université de Montréal, rue Saint-Denis, Que, H2X 0A9, Canada.

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http://dx.doi.org/10.1364/BOE.6.005063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679278PMC
December 2015

Digital Breast Tomosynthesis guided Near Infrared Spectroscopy: Volumetric estimates of fibroglandular fraction and breast density from tomosynthesis reconstructions.

Biomed Phys Eng Express 2015;1(4). Epub 2015 Oct 27.

Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA; Department of Radiology, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA.

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http://dx.doi.org/10.1088/2057-1976/1/4/045202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771071PMC
October 2015

Review of fluorescence guided surgery visualization and overlay techniques.

Biomed Opt Express 2015 Oct 3;6(10):3765-82. Epub 2015 Sep 3.

Thayer School of Engineering, Dartmouth College, 14 Engineering Drive, Hanover, NH 03755, USA ; Department of Surgery, Geisel School of Medicine at Dartmouth, 1 Rope Ferry Road, Hanover, NH 03755, USA.

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http://dx.doi.org/10.1364/BOE.6.003765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605037PMC
October 2015

MR-Guided Near-Infrared Spectral Tomography Increases Diagnostic Performance of Breast MRI.

Clin Cancer Res 2015 Sep 27;21(17):3906-12. Epub 2015 May 27.

Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire. Department of Diagnostic Radiology, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763338PMC
September 2015

Direct regularization from co-registered anatomical images for MRI-guided near-infrared spectral tomographic image reconstruction.

Biomed Opt Express 2015 Sep 27;6(9):3618-30. Epub 2015 Aug 27.

Thayer School of Engineering, Dartmouth College, Hanover NH 03755, USA.

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http://dx.doi.org/10.1364/BOE.6.003618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574684PMC
September 2015

Optimization of image reconstruction for magnetic resonance imaging-guided near-infrared diffuse optical spectroscopy in breast.

J Biomed Opt 2015 May;20(5):56009

Dartmouth College, Thayer School of Engineering, Hanover, New Hampshire 03755, United StatesbDartmouth College, Geisel School of Medicine, Department of Community and Family Medicine, Hanover, New Hampshire 03755, United StatescDartmouth College, Geisel S.

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http://biomedicaloptics.spiedigitallibrary.org/article.aspx?
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http://dx.doi.org/10.1117/1.JBO.20.5.056009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572095PMC
May 2015

Molecular dyes used for surgical specimen margin orientation allow for intraoperative optical assessment during breast conserving surgery.

J Biomed Opt 2015 Apr;20(4):040504

Dartmouth College, Thayer School of Engineering, 14 Engineering Drive, Hanover, New Hampshire 03755, United StatescDartmouth College, Department of Surgery, Geisel School of Medicine, 1 Rope Ferry Road, Hanover, New Hampshire 03755, United States.

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http://biomedicaloptics.spiedigitallibrary.org/data/Journals
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http://biomedicaloptics.spiedigitallibrary.org/article.aspx?
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http://dx.doi.org/10.1117/1.JBO.20.4.040504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406078PMC
April 2015

Structured light scatteroscopy.

J Biomed Opt 2014 ;19(7):070504

Dartmouth College, Thayer School of Engineering, 14 Engineering Drive, Hanover, New Hampshire 03755, United States.

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http://dx.doi.org/10.1117/1.JBO.19.7.070504DOI Listing
February 2015

Predicting breast tumor response to neoadjuvant chemotherapy with diffuse optical spectroscopic tomography prior to treatment.

Clin Cancer Res 2014 Dec 7;20(23):6006-15. Epub 2014 Oct 7.

Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire. Department of Diagnostic Radiology, Giesel School of Medicine, Hanover, New Hampshire.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-1415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254218PMC
December 2014

Cortical surface shift estimation using stereovision and optical flow motion tracking via projection image registration.

Med Image Anal 2014 Oct 9;18(7):1169-83. Epub 2014 Jul 9.

Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA; Geisel School of Medicine, Dartmouth College, Hanover, NH 03755, USA.

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http://dx.doi.org/10.1016/j.media.2014.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158407PMC
October 2014

Stereovision to MR image registration for cortical surface displacement mapping to enhance image-guided neurosurgery.

Med Phys 2014 Oct;41(10):102302

Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755; Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire 03755; Norris Cotton Cancer Center, Lebanon, New Hampshire 03756; and Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire 03756.

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http://dx.doi.org/10.1118/1.4894705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176089PMC
October 2014

Sensitivity of MRI-guided near-infrared spectroscopy clinical breast exam data and its impact on diagnostic performance.

Biomed Opt Express 2014 Sep 22;5(9):3103-15. Epub 2014 Aug 22.

Thayer School of Engineering, Dartmouth College, Hanover NH 03755 USA ; Department of Diagnostic Radiology, Geisel School of Medicine, Dartmouth College, Hanover, NH03755 USA ;

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https://www.osapublishing.org/boe/abstract.cfm?uri=boe-5-9-3
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http://dx.doi.org/10.1364/BOE.5.003103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230863PMC
September 2014

Supine breast MRI and 3D optical scanning: a novel approach to improve tumor localization for breast conserving surgery.

Ann Surg Oncol 2014 Jul 12;21(7):2203-8. Epub 2014 Mar 12.

Thayer School of Engineering, Dartmouth College, Hanover, NH, USA.

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http://dx.doi.org/10.1245/s10434-014-3598-5DOI Listing
July 2014

Microwave open-ended coaxial dielectric probe: interpretation of the sensing volume re-visited.

BMC Med Phys 2014 17;14. Epub 2014 Jun 17.

Thayer School of Engineering, Dartmouth College, 14 Engineering Drive, Hanover, NH 03755, USA.

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http://dx.doi.org/10.1186/1756-6649-14-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083041PMC
July 2014

5-Aminolevulinic acid-induced protoporphyrin IX fluorescence in meningioma: qualitative and quantitative measurements in vivo.

Neurosurgery 2014 Mar;10 Suppl 1:74-82; discussion 82-3

*Section of Neurosurgery, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire; ‡Thayer School of Engineering, Hanover, New Hampshire; §Geisel School of Medicine at Dartmouth, Hanover, New Hampshire; ‖Departments of Pathology and Neurology, Georgetown University Medical Center, Washington, DC; ¶Ontario Cancer Institute, University of Toronto, Toronto, Ontario, Canada; #Engineering Physics Department, École Polytechnique de Montréal, Montreal, Quebec, Canada; **Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.

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http://dx.doi.org/10.1227/NEU.0000000000000117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237006PMC
March 2014

3D multislab, multishot acquisition for fast, whole-brain MR elastography with high signal-to-noise efficiency.

Magn Reson Med 2014 Feb;71(2):477-85

Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA; Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.

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http://dx.doi.org/10.1002/mrm.25065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061282PMC
February 2014

Adaptable near-infrared spectroscopy fiber array for improved coupling to different breast sizes during clinical MRI.

Acad Radiol 2014 Feb;21(2):141-50

Thayer School of Engineering, Dartmouth College, 14 Engineering Dr., Hanover, NH 03755; Department of Diagnostic Radiology, Dartmouth Medical School, Lebanon, NH.

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http://dx.doi.org/10.1016/j.acra.2013.09.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778710PMC
February 2014

System and methods for wide-field quantitative fluorescence imaging during neurosurgery.

Opt Lett 2013 Aug;38(15):2786-8

Section of Neurosurgery, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA.

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http://dx.doi.org/10.1364/OL.38.002786DOI Listing
August 2013