Keith A Wesnes

Keith A Wesnes

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Keith A Wesnes

Keith A Wesnes

Publications by authors named "Keith A Wesnes"

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Mild Behavioral Impairment as a Marker of Cognitive Decline in Cognitively Normal Older Adults.

Am J Geriatr Psychiatry 2019 Feb 2. Epub 2019 Feb 2.

University of Exeter Medical School (BC, HB, KAW, AC, CB), University of Exeter, Exeter, UK.

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http://dx.doi.org/10.1016/j.jagp.2019.01.215DOI Listing
February 2019

Longitudinal changes in global and domain specific cognitive function in the very-old: findings from the Newcastle 85+ Study.

Int J Geriatr Psychiatry 2018 02 22;33(2):298-306. Epub 2017 Jun 22.

Institute of Health and Society, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1002/gps.4743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811803PMC
February 2018

Impaired verbal episodic memory in healthy older adults is marked by increased F-Isoprostanes.

Prostaglandins Leukot Essent Fatty Acids 2018 02 3;129:32-37. Epub 2018 Feb 3.

Centre for Human Psychopharmacology, Swinburne University of Technology, Melbourne, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.plefa.2018.02.001DOI Listing
February 2018

Does attentional dysfunction and thalamic atrophy predict decline in dementia with Lewy bodies?

Parkinsonism Relat Disord 2017 Dec 9;45:69-74. Epub 2017 Oct 9.

Institute of Neuroscience, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, NE4 5PL, UK; Department of Psychiatry, University of Cambridge, Cambridge, CB2 0QC, UK.

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http://dx.doi.org/10.1016/j.parkreldis.2017.10.006DOI Listing
December 2017

Homocysteine, Tryptophan, and Cognition in the Very Old.

J Am Med Dir Assoc 2017 10 23;18(10):895-896. Epub 2017 Aug 23.

School of Agriculture Food and Rural Development, Newcastle University, Newcastle-upon-Tyne, United Kingdom; Newcastle University Institute for Aging, Newcastle-upon-Tyne, United Kingdom; Human Nutrition Research Center, Newcastle University, Newcastle-upon-Tyne, United Kingdom; Institute of Cellular Medicine, Newcastle University, Newcastle-upon-Tyne, United Kingdom.

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http://dx.doi.org/10.1016/j.jamda.2017.07.010DOI Listing
October 2017

One-Carbon Metabolism Biomarkers and Cognitive Decline in the Very Old: The Newcastle 85+ Study.

J Am Med Dir Assoc 2017 Sep 21;18(9):806.e19-806.e27. Epub 2017 Jun 21.

School of Agriculture, Food, and Rural Development, Newcastle University, Newcastle-upon-Tyne, UK; Newcastle University Institute for Ageing, Newcastle-upon-Tyne, UK; Human Nutrition Research Centre, Newcastle University, Newcastle-upon-Tyne, UK; Institute of Cellular Medicine, Newcastle University, Newcastle-upon-Tyne, UK.

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http://dx.doi.org/10.1016/j.jamda.2017.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576913PMC
September 2017

Effects of levomilnacipran extended-release on major depressive disorder patients with cognitive impairments: post-hoc analysis of a phase III study.

Int Clin Psychopharmacol 2017 03;32(2):72-79

aWesnes Cognition Ltd, Streatley on Thames bDepartment of Psychology, Northumbria University, Newcastle, UK cCentre for Human Psychopharmacology, Swinburne University, Melbourne, Victoria, Australia dAllergan, Jersey City, New Jersey eInstitute for Advanced Medical Research, Alpharetta, Georgia fDepartment of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, Florida, USA gMood Disorders Psychopharmacology Unit, University Health Network, Toronto, Ontario, Canada.

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http://pdfs.journals.lww.com/intclinpsychopharm/2017/03000/E
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http://dx.doi.org/10.1097/YIC.0000000000000157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5265686PMC
March 2017

Effects of the Red Bull energy drink on cognitive function and mood in healthy young volunteers.

J Psychopharmacol 2017 02 14;31(2):211-221. Epub 2016 Dec 14.

5 Medicinal Plant Research Group, Newcastle University, Newcastle, UK.

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http://dx.doi.org/10.1177/0269881116681459DOI Listing
February 2017

Differences in memory function between 5-HT1A receptor genotypes in patients with major depressive disorder.

CNS Spectr 2016 Oct 19;21(5):379-384. Epub 2016 Jan 19.

4Global Translational Medicine & Early Development,Sunovion Pharmaceuticals Inc.,Marlborough,Massachusetts,USA.

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http://dx.doi.org/10.1017/S1092852915000802DOI Listing
October 2016

Practice effects due to serial cognitive assessment: Implications for preclinical Alzheimer's disease randomized controlled trials.

Alzheimers Dement (Amst) 2015 Mar 29;1(1):103-11. Epub 2015 Mar 29.

Departments of Psychiatry, Neurology, and Gerontology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1016/j.dadm.2014.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876902PMC
March 2015

Memantine improves attention and episodic memory in Parkinson's disease dementia and dementia with Lewy bodies.

Int J Geriatr Psychiatry 2015 Jan 16;30(1):46-54. Epub 2014 Apr 16.

Wesnes Cognition Ltd, Streatley on Thames, UK; Department of Psychology, Northumbria University, Newcastle, UK; Centre for Human Psychopharmacology, Swinburne University, Melbourne, Australia.

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http://dx.doi.org/10.1002/gps.4109DOI Listing
January 2015

Moving beyond the pros and cons of automating cognitive testing in pathological aging and dementia: the case for equal opportunity.

Authors:
Keith A Wesnes

Alzheimers Res Ther 2014 29;6(5):58. Epub 2014 Aug 29.

Wesnes Cognition, Little Paddock, Streatley Hill, Streatley on Thames, RG8 9RD, UK ; Department of Psychology, Northumbria University, Ellison Place 2, Newcastle-upon-Tyne, NE1 8ST, UK ; Centre for Human Psychopharmacology, Swinburne University, John St, Melbourne 3122, VIC, Australia.

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http://dx.doi.org/10.1186/s13195-014-0058-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255527PMC
December 2014

The role of human cognitive neuroscience in drug discovery for the dementias.

Curr Opin Pharmacol 2014 Feb 22;14:62-73. Epub 2013 Dec 22.

Formerly Bracket, Goring-on-Thames, UK.

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http://dx.doi.org/10.1016/j.coph.2013.12.001DOI Listing
February 2014

Effects of nicotine withdrawal on cognition in a clinical trial setting.

Psychopharmacology (Berl) 2013 Sep 17;229(1):133-40. Epub 2013 Apr 17.

Bracket, 19 Gatehampton Road, Goring-on-Thames, Oxon RG8 0EN, UK.

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http://link.springer.com/content/pdf/10.1007/s00213-013-3089
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http://link.springer.com/10.1007/s00213-013-3089-6
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http://dx.doi.org/10.1007/s00213-013-3089-6DOI Listing
September 2013

An evaluation of the cognitive and mood effects of an energy shot over a 6h period in volunteers: a randomized, double-blind, placebo controlled, cross-over study.

Appetite 2013 Aug 12;67:105-13. Epub 2013 Apr 12.

Bracket Global, Gatehampton Road, Goring-on-Thames RG8 0EN, UK.

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http://dx.doi.org/10.1016/j.appet.2013.04.005DOI Listing
August 2013

Breakfast is associated with enhanced cognitive function in schoolchildren. An internet based study.

Appetite 2012 Dec 15;59(3):646-9. Epub 2012 Aug 15.

Bracket Global, Gatehampton Road, Goring-on-Thames, RG8 0EN, UK.

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http://dx.doi.org/10.1016/j.appet.2012.08.008DOI Listing
December 2012

The cognitive profile of type 1 Gaucher disease patients.

J Inherit Metab Dis 2012 Nov 21;35(6):1093-9. Epub 2012 Feb 21.

Department of Internal Medicine, Academic Medical Center, F5-169, Box 22700, 1100 DE, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10545-012-9460-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470680PMC
November 2012

The effect of high lactose-isomaltulose on cognitive performance of young children. A double blind cross-over design study.

Appetite 2012 Feb 29;58(1):81-7. Epub 2011 Sep 29.

Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor Darul Ehsan, Malaysia.

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http://dx.doi.org/10.1016/j.appet.2011.09.004DOI Listing
February 2012

Acute ingestion of different macronutrients differentially enhances aspects of memory and attention in healthy young adults.

Biol Psychol 2012 Feb 3;89(2):477-86. Epub 2012 Jan 3.

Department of Psychology, Fylde College, University of Lancaster, Lancaster LA1 4YF, UK.

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http://dx.doi.org/10.1016/j.biopsycho.2011.12.017DOI Listing
February 2012

The effects of acute tryptophan depletion on neuropsychological function, mood and movement in the healthy elderly.

J Psychopharmacol 2011 Oct 24;25(10):1337-43. Epub 2011 Jan 24.

School of Medicine and Pharmacology, University of Western Australia, Perth, Australia.

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http://dx.doi.org/10.1177/0269881110389094DOI Listing
October 2011

Evaluation of techniques to identify beneficial effects of nutrition and natural products on cognitive function.

Authors:
Keith A Wesnes

Nutr Rev 2010 Nov;68 Suppl 1:S22-8

United BioSource Corporation, Goring-on-Thames, RG8 0EN, United Kingdom.

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http://dx.doi.org/10.1111/j.1753-4887.2010.00328.xDOI Listing
November 2010

Does a neuropsychological index of hemispheric lateralization predict onset of upper respiratory tract infectious symptoms?

Br J Health Psychol 2010 Sep 18;15(Pt 3):469-77. Epub 2009 Sep 18.

School of Health Sciences and Social Care, Brunel University, London, UK.

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http://dx.doi.org/10.1348/135910709X471391DOI Listing
September 2010

Healthy middle-aged individuals are vulnerable to cognitive deficits as a result of increased arterial stiffness.

J Hypertens 2010 Aug;28(8):1724-9

NICM Centre for Study of Natural Medicines and Neurocognition, Brain Sciences Institute, Swinburne University of Technology, Melbourne, Australia.

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https://insights.ovid.com/crossref?an=00004872-201008000-000
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http://dx.doi.org/10.1097/HJH.0b013e32833b1ee7DOI Listing
August 2010

Genetic variation of CHRNA4 does not modulate attention in Parkinson's disease.

Neurosci Lett 2010 Jul 20;479(2):123-5. Epub 2010 May 20.

Mitochondrial Research Group, University of Newcastle Upon Tyne, United Kingdom.

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http://dx.doi.org/10.1016/j.neulet.2010.05.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038490PMC
July 2010

Differential effects of the aromas of Salvia species on memory and mood.

Hum Psychopharmacol 2010 Jul;25(5):388-96

Department of Psychology, Brain, Performance and Nutrition Research Centre, Northumbria University, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1002/hup.1129DOI Listing
July 2010

Evaluation of dementia rating scales in Parkinson's disease dementia.

Am J Alzheimers Dis Other Demen 2010 Mar 9;25(2):142-8. Epub 2009 Apr 9.

Emory University School of Medicine, 101 Woodruff Circle, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1177/1533317509333904DOI Listing
March 2010

Armodafinil for treatment of excessive sleepiness associated with shift work disorder: a randomized controlled study.

Mayo Clin Proc 2009 Nov;84(11):958-72

Division of Sleep Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/S0025-6196(11)60666-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770907PMC
November 2009

The effect of modafinil on cognitive function in breast cancer survivors.

Cancer 2009 Jun;115(12):2605-16

Department of Medicine and Radiation Oncology, James P. Wilmot Cancer Center, University of Rochester, Rochester School of Medicine and Dentistry, Rochester, New York, USA.

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http://dx.doi.org/10.1002/cncr.24287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796482PMC
June 2009

Estradiol treatment and its interaction with the cholinergic system: effects on cognitive function in healthy young women.

Horm Behav 2008 Nov 29;54(5):684-93. Epub 2008 Jul 29.

Brain Sciences Institute, Faculty of Life and Social Sciences, Swinburne University of Technology, VIC, Australia.

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http://dx.doi.org/10.1016/j.yhbeh.2008.07.007DOI Listing
November 2008

Assessing change in cognitive function in dementia: the relative utilities of the Alzheimer's Disease Assessment Scale-Cognitive Subscale and the Cognitive Drug Research system.

Authors:
Keith A Wesnes

Neurodegener Dis 2008 6;5(3-4):261-3. Epub 2008 Mar 6.

Cognitive Drug Research Ltd., Goring-on-Thames, UK.

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http://dx.doi.org/10.1159/000113719DOI Listing
May 2008

An extract of Salvia (sage) with anticholinesterase properties improves memory and attention in healthy older volunteers.

Psychopharmacology (Berl) 2008 May 19;198(1):127-39. Epub 2008 Mar 19.

Brain Sciences Institute, Swinburne University, Melbourne, VIC, 3122, Australia.

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http://dx.doi.org/10.1007/s00213-008-1101-3DOI Listing
May 2008

The cognitive effects of modulating the glycine site of the NMDA receptor with high-dose glycine in healthy controls.

Hum Psychopharmacol 2008 Mar;23(2):151-9

Behavioural Neuroscience Laboratory, School of Psychology, Psychiatry and Psychological Medicine, Monash University, Victoria, Australia.

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http://dx.doi.org/10.1002/hup.904DOI Listing
March 2008

The effects of L-theanine, caffeine and their combination on cognition and mood.

Biol Psychol 2008 Feb 26;77(2):113-22. Epub 2007 Sep 26.

Human Cognitive Neuroscience Unit, Division of Psychology, Northumbria University, Newcastle upon Tyne NE1 8ST, UK.

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http://www.noopills.com/wp-content/uploads/2016/04/The-effec
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http://linkinghub.elsevier.com/retrieve/pii/S030105110700157
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http://dx.doi.org/10.1016/j.biopsycho.2007.09.008DOI Listing
February 2008

Cognition assessment in paediatric clinical trials.

Drug Discov Today 2008 Jan 26;13(1-2):79-85. Epub 2007 Nov 26.

Cognitive Drug Research Ltd., CDR House, Goring-on-Thames, UK.

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http://dx.doi.org/10.1016/j.drudis.2007.10.006DOI Listing
January 2008

A low glycaemic index breakfast cereal preferentially prevents children's cognitive performance from declining throughout the morning.

Appetite 2007 Jul 16;49(1):240-4. Epub 2007 Jan 16.

Cognition and Communication Research Centre, Division of Psychology, University of Northumbria, Newcastle upon Tyne NE1 8ST, UK.

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http://dx.doi.org/10.1016/j.appet.2006.06.009DOI Listing
July 2007

Cognitive function testing: the case for standardization and automation.

Authors:
Keith A Wesnes

J Br Menopause Soc 2006 Dec;12(4):158-63

Cognitive Drug Research, Goring-on-Thames, UK.

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http://dx.doi.org/10.1258/136218006779160544DOI Listing
December 2006

Orthostatic hypotension in Parkinson's disease: association with cognitive decline?

Int J Geriatr Psychiatry 2006 Aug;21(8):778-83

Parkinson's Disease Research Unit, Department of Neurology, Sunderland Royal Hospital, Sunderland, UK.

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http://dx.doi.org/10.1002/gps.1562DOI Listing
August 2006

Muscarinic and nicotinic receptors synergistically modulate working memory and attention in humans.

Int J Neuropsychopharmacol 2006 Apr 9;9(2):175-89. Epub 2005 May 9.

Behavioural Neuroscience Laboratory, Department of Physiology, Monash Centre for Brain and Behaviour, Monash University, Melbourne Australia.

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http://dx.doi.org/10.1017/S1461145705005407DOI Listing
April 2006

Pharmacodynamic effects of darifenacin, a muscarinic M selective receptor antagonist for the treatment of overactive bladder, in healthy volunteers.

BJU Int 2005 Nov;96(7):1055-62

Washington Neuropsychological Institute, Washington, DC 20008, USA.

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http://dx.doi.org/10.1111/j.1464-410X.2005.05745.xDOI Listing
November 2005

Combined D1/D2 receptor stimulation under conditions of dopamine depletion impairs spatial working memory performance in humans.

Psychopharmacology (Berl) 2005 Oct 29;181(4):771-80. Epub 2005 Sep 29.

Brain Sciences Institute, Swinburne University of Technology, Melbourne, Australia.

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http://link.springer.com/10.1007/s00213-005-0019-2
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http://dx.doi.org/10.1007/s00213-005-0019-2DOI Listing
October 2005

Cognitive and mood improvements of caffeine in habitual consumers and habitual non-consumers of caffeine.

Psychopharmacology (Berl) 2005 Jun 28;179(4):813-25. Epub 2005 Jan 28.

Human Cognitive Neuroscience Unit, Division of Psychology, Northumbria University, Newcastle upon Tyne, NE1 8ST, UK.

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http://dx.doi.org/10.1007/s00213-004-2104-3DOI Listing
June 2005

Short-term transdermal estradiol therapy, cognition and depressive symptoms in healthy older women. A randomised placebo controlled pilot cross-over study.

Psychoneuroendocrinology 2005 May 2;30(4):309-15. Epub 2004 Dec 2.

Department of Medicine for the Elderly, Faculty of Medicine, Imperial College, Hammersmith Hospital, Du Cane Road, London W12 ONN, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S030645300400155
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http://dx.doi.org/10.1016/j.psyneuen.2004.08.007DOI Listing
May 2005

Baseline plasma GABA: its relationship to the adverse effects of acute lorazepam administration on cognition in the elderly.

Neurochem Res 2004 Dec;29(12):2311-5

Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA.

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December 2004

Effect of galantamine hydrobromide in chronic fatigue syndrome: a randomized controlled trial.

JAMA 2004 Sep;292(10):1195-204

Department of Health and Social Sciences, University of Exeter, Exeter, England.

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http://dx.doi.org/10.1001/jama.292.10.1195DOI Listing
September 2004

Hallucinations predict attentional improvements with rivastigmine in dementia with lewy bodies.

Dement Geriatr Cogn Disord 2004 14;18(1):94-100. Epub 2004 Apr 14.

Institute for Ageing and Health, Newcastle General Hospital, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1159/000077816DOI Listing
July 2004

Simultaneous depletion of serotonin and catecholamines impairs sustained attention in healthy female subjects without affecting learning and memory.

J Psychopharmacol 2004 Mar;18(1):21-31

Neuropsychopharmacology Laboratory, Brain Sciences Institute, Swinburne University of Technology, Melbourne, Australia.

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http://dx.doi.org/10.1177/0269881104040215DOI Listing
March 2004

Selective effects of acute serotonin and catecholamine depletion on memory in healthy women.

J Psychopharmacol 2004 Mar;18(1):32-40

Neuropsychopharmacology Laboratory, Brain Sciences Institute, Swinburne University of Technology, Melbourne Australia.

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http://dx.doi.org/10.1177/0269881104040225DOI Listing
March 2004

Breakfast reduces declines in attention and memory over the morning in schoolchildren.

Appetite 2003 Dec;41(3):329-31

Cognitive Drug Research Ltd, Reading RG30 1EA, UK.

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December 2003

The evaluation of cognitive function in the dementias: methodological and regulatory considerations.

Dialogues Clin Neurosci 2003 Mar;5(1):77-88

Cognitive Drug Research Ltd, Reading, UK; Human Cognitive Neuroscience Unit, Northumbria University, Newcastle upon Tyne, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181711PMC
March 2003

Reboxetine versus paroxetine versus placebo: effects on cognitive functioning in depressed patients.

Int Clin Psychopharmacol 2003 Jan;18(1):9-14

University of Utah, Salt Lake City, Utah, USA.

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http://dx.doi.org/10.1097/01.yic.0000048749.53980.bfDOI Listing
January 2003

Basal activity of the HPA axis and cognitive function in anorexia nervosa.

Int J Neuropsychopharmacol 2002 Mar;5(1):17-25

Division of Psychology, University of Northumbria, New Castle upon Tyne, UK.

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March 2002

Hepatitis C and cognitive impairment in a cohort of patients with mild liver disease.

Hepatology 2002 Feb;35(2):433-9

Hepatology Section, Division of Medicine A, Faculty of Medicine, Imperial College, St Mary's Hospital, London, UK.

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http://dx.doi.org/10.1053/jhep.2002.30688DOI Listing
February 2002