Publications by authors named "Keith A Josephs"

100Publications

Communication Limitations in Patients With Progressive Apraxia of Speech and Aphasia.

Am J Speech Lang Pathol 2020 Aug 5:1-11. Epub 2020 Aug 5.

Department of Neurology, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1044/2020_AJSLP-20-00012DOI Listing
August 2020

Dementia with Lewy bodies presenting as Logopenic variant primary progressive Aphasia.

Neurocase 2020 Jul 16:1-5. Epub 2020 Jul 16.

Department of Neurology, Mayo Clinic , Rochester, Minnesota, USA.

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http://dx.doi.org/10.1080/13554794.2020.1795204DOI Listing
July 2020

PSP-like syndrome after aortic surgery in adults (Mokri syndrome).

Neurol Clin Pract 2020 Jun;10(3):245-254

Department of Neurology (SMT, JEA, JRD, KAJ), Mayo Clinic, Rochester, MN; and Department of Neurology (JYM), University of Minnesota, Minneapolis, MN.

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http://dx.doi.org/10.1212/CPJ.0000000000000708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292559PMC
June 2020

Clinical and pathologic features of cognitive-predominant corticobasal degeneration.

Neurology 2020 07 9;95(1):e35-e45. Epub 2020 Jun 9.

From the Departments of Neuroscience (N.S., M.E.M., D.W.D.), Psychiatry and Psychology (O.A.S., O.P.), and Neurology (R.J.U., Z.K.W., N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Department of Neurology (I.L.), University of California San Diego, La Jolla; Department of Neurology (R.D.), Mount Sinai Medical Center, Miami Beach, FL; and Department of Neurology (K.A.J.), Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1212/WNL.0000000000009734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371382PMC
July 2020

Utility of FDG-PET in diagnosis of Alzheimer-related TDP-43 proteinopathy.

Neurology 2020 07 9;95(1):e23-e34. Epub 2020 Jun 9.

From the Departments of Neurology (M.B., H.B., D.T.J., D.S.K., B.F.B., R.C.P., K.A.J.), Radiology (C.G.S., M.L.S., C.R.J., V.L., J.L.W.), and Laboratory Medicine and Pathology (J.E.P.), Mayo Clinic, Rochester, MN; and Department of Neuroscience (M.E.M., L.P., D.W.D.), Mayo Clinic, Jacksonville, FL.

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http://dx.doi.org/10.1212/WNL.0000000000009722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371379PMC
July 2020

Cerebrovascular pathology and misdiagnosis of multiple system atrophy: An autopsy study.

Parkinsonism Relat Disord 2020 06 16;75:34-40. Epub 2020 May 16.

Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2020.05.018DOI Listing
June 2020

Dysphagia in Progressive Supranuclear Palsy.

Dysphagia 2020 Aug 1;35(4):667-676. Epub 2019 Nov 1.

Department of Neurology, Mayo Clinic, 200 1st Street S.W., Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1007/s00455-019-10073-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192765PMC
August 2020

Progressive supranuclear palsy is not associated with neurogenic orthostatic hypotension.

Neurology 2019 10 4;93(14):e1339-e1347. Epub 2019 Sep 4.

From the Departments of Neurology (J.A.v.G., R.H.A.-S., P.W.T., Z.K.W., R.J.U., W.P.C.), Psychiatry and Psychology (T.J.F.), and Neuroscience (D.W.D.) and Division of Biomedical Statistics and Informatics (M.G.H.), Mayo Clinic, Jacksonville, FL; and Department of Neurology (E.E.B., W.S., J.K.C.-G., K.A.J., P.A.L., J.E.A.) and Division of Biomedical Statistics and Informatics (D.E.B.), Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1212/WNL.0000000000008197DOI Listing
October 2019

Clinicopathologic subtype of Alzheimer's disease presenting as corticobasal syndrome.

Alzheimers Dement 2019 09 6;15(9):1218-1228. Epub 2019 Aug 6.

Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2019.04.011DOI Listing
September 2019

Utility of the Movement Disorders Society Criteria for Progressive Supranuclear Palsy in Clinical Practice.

Mov Disord Clin Pract 2019 Jul 24;6(6):436-439. Epub 2019 Jul 24.

Department of Neurology Mayo Clinic Rochester Minnesota USA.

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http://dx.doi.org/10.1002/mdc3.12807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660232PMC
July 2019

Cross-sectional associations of tau-PET signal with cognition in cognitively unimpaired adults.

Neurology 2019 07 30;93(1):e29-e39. Epub 2019 May 30.

From the Departments of Radiology (V.J.L., T.J.B., H.-K.M., P.F., M.L.S., M.K.P., K.K., D.T.J., P.V., C.G.S., C.R.J.), Health Sciences Research (H.J.W., S.D.W., T.M.T., M.M. Mielke, R.O.R.), Information Technology (M.L.S.), Neurology (B.F.B., K.A.J., D.T.J., J.G.-R., M.M. Mielke, D.S.K., R.C.P.), Neuroscience (M.E.M.), and Psychiatry and Psychology (M.M. Machulda), Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1212/WNL.0000000000007728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659005PMC
July 2019

Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases.

Neurology 2019 02;92(7):329-337

From the UC Gardner Neuroscience Institute and Gardner Family Center for Parkinson's Disease and Movement Disorders (A.J.E., J.A.V., L.M., A.M.), Department of Neurology, University of Cincinnati, OH; Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic (A.E.L., A.F.), Toronto Western Hospital, University of Toronto; Krembil Research Institute (A.E.L., A.F.), Toronto, Canada; Parkinson's Disease and Movement Disorders Center (D.K.S.), Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA; College of Medicine (K.A.J.), Mayo Clinic, Rochester, MN; Institute of Molecular and Clinical Sciences (F.M.), St George's University of London, UK; Division of Movement Disorders (R.S.), Department of Neurology and Department of Health Science Research, Mayo Clinic College of Medicine, Rochester, MN; Department of Neurology and the Pittsburgh Institute for Neurodegenerative Diseases (J.T.G., F.C.), University of Pittsburgh, PA; Department of Neurology (T.R.Y.), University of Kentucky, Lexington; Parkinson's Disease Research, Education and Clinical Center (C.M.T.), Neurology, San Francisco Veterans Affairs Medical Center; Department of Neurology (C.M.T.), University of California-San Francisco; Department of Neurology & Neurosurgery, Montreal Neurological Institute, and Department of Human Genetics (Z.G.-O.), McGill University, Canada; Parkinson & Other Movement Disorders Center UC San Diego (I.L.), Department of Neurosciences, Altman Clinical Translational Research Institute, La Jolla, CA; VA Puget Sound Health Care System and Department of Neurology (I.F.M., CP.Z.), University of Washington, Seattle; Department of Neurology (I.F.M.), University of Washington School of Medicine, Seattle; Center for Neurodegenerative Science (P.B.), Van Andel Research Institute, Grand Rapids, MI; Center for Neurological Restoration (H.H.F.) and Lou Ruvo Center for Brain Health, Neurological Institute (J.B.L.), Cleveland Clinic, OH; Department of Neurology (D.G.S.), University of Alabama at Birmingham; Consultorio y Laboratorio de Neurogenética (M.A.K.), Centro Universitario de Neurología "José María Ramos Mejía" y División Neurología, Hospital JM Ramos Mejía, Facultad de Medicina, UBA; Programa de Medicina de Precision y Genomica Clinica (M.A.K.), Instituto de Investigaciones en Medicina Traslacional, Facultad de Ciencias Biomédicas, Universidad Austral-CONICET, Buenos Aires, Argentina; Department of Neurology (M.A.S.), Massachusetts General Hospital, Boston; Division of Neuroscience (S.P.S.), Sanofi-Genzyme, Framingham, MA; Michael J. Fox Foundation for Parkinson's Research (T.S.), New York, NY; and College of Sciences (G.P.), University of Texas at San Antonio.

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http://dx.doi.org/10.1212/WNL.0000000000006926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382364PMC
February 2019

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.

Authors:
Cyril Pottier Yingxue Ren Ralph B Perkerson Matt Baker Gregory D Jenkins Marka van Blitterswijk Mariely DeJesus-Hernandez Jeroen G J van Rooij Melissa E Murray Elizabeth Christopher Shannon K McDonnell Zachary Fogarty Anthony Batzler Shulan Tian Cristina T Vicente Billie Matchett Anna M Karydas Ging-Yuek Robin Hsiung Harro Seelaar Merel O Mol Elizabeth C Finger Caroline Graff Linn Öijerstedt Manuela Neumann Peter Heutink Matthis Synofzik Carlo Wilke Johannes Prudlo Patrizia Rizzu Javier Simon-Sanchez Dieter Edbauer Sigrun Roeber Janine Diehl-Schmid Bret M Evers Andrew King M Marsel Mesulam Sandra Weintraub Changiz Geula Kevin F Bieniek Leonard Petrucelli Geoffrey L Ahern Eric M Reiman Bryan K Woodruff Richard J Caselli Edward D Huey Martin R Farlow Jordan Grafman Simon Mead Lea T Grinberg Salvatore Spina Murray Grossman David J Irwin Edward B Lee EunRan Suh Julie Snowden David Mann Nilufer Ertekin-Taner Ryan J Uitti Zbigniew K Wszolek Keith A Josephs Joseph E Parisi David S Knopman Ronald C Petersen John R Hodges Olivier Piguet Ethan G Geier Jennifer S Yokoyama Robert A Rissman Ekaterina Rogaeva Julia Keith Lorne Zinman Maria Carmela Tartaglia Nigel J Cairns Carlos Cruchaga Bernardino Ghetti Julia Kofler Oscar L Lopez Thomas G Beach Thomas Arzberger Jochen Herms Lawrence S Honig Jean Paul Vonsattel Glenda M Halliday John B Kwok Charles L White Marla Gearing Jonathan Glass Sara Rollinson Stuart Pickering-Brown Jonathan D Rohrer John Q Trojanowski Vivianna Van Deerlin Eileen H Bigio Claire Troakes Safa Al-Sarraj Yan Asmann Bruce L Miller Neill R Graff-Radford Bradley F Boeve William W Seeley Ian R A Mackenzie John C van Swieten Dennis W Dickson Joanna M Biernacka Rosa Rademakers

Acta Neuropathol 2019 06 9;137(6):879-899. Epub 2019 Feb 9.

Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.

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http://link.springer.com/10.1007/s00401-019-01962-9
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http://dx.doi.org/10.1007/s00401-019-01962-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533145PMC
June 2019

The influence of β-amyloid on [F]AV-1451 in semantic variant of primary progressive aphasia.

Neurology 2019 02 11;92(7):e710-e722. Epub 2019 Jan 11.

From the Departments of Radiology (J.L.W., C.G.S., I.S., M.L.S., C.R.J., V.J.L.), Health Science Research (Biostatistics) (P.R.M., S.D.W.), Neurology (Speech Pathology) (J.R.D., H.M.C., R.L.U.), Psychiatry and Psychology (M.M.M.), Neurology (Behavioral Neurology) (H.B., J.G.-R., D.T.J., B.F.B., D.S.K., R.C.P., K.A.J.), and Information Technology (M.L.S.), Mayo Clinic, Rochester, MN; and Department of Neuroscience (N.E.-T.), Mayo Clinic, Jacksonville, FL.

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http://dx.doi.org/10.1212/WNL.0000000000006913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382367PMC
February 2019

Quantitative assessment of grammar in amyloid-negative logopenic aphasia.

Brain Lang 2018 11 8;186:26-31. Epub 2018 Sep 8.

Department of Neurology (Division of Behavioral Neurology and Movement Disorders), Mayo Clinic, Rochester, MN, United States.

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http://dx.doi.org/10.1016/j.bandl.2018.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299833PMC
November 2018

Fitting TDP-43 into the APOE ε4 and neurodegeneration story.

Authors:
Keith A Josephs

Lancet Neurol 2018 09 6;17(9):735-737. Epub 2018 Aug 6.

Department of Neurology, Mayo Clinic, College of Medicine and Graduate School, Rochester, MN 55905, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14744422183028
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http://dx.doi.org/10.1016/S1474-4422(18)30288-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200403PMC
September 2018

Diffuse Lewy body disease manifesting as corticobasal syndrome: A rare form of Lewy body disease.

Neurology 2018 07 13;91(3):e268-e279. Epub 2018 Jun 13.

From the Departments of Neuroscience (K.K., M.E.M., S.K., N.S., J.A.V.G., D.W.D.), Psychiatry and Psychology (T.J.F., A.P.), and Neurology (T.K., R.J.U., N.R.G.-R., Z.K.W.), Mayo Clinic, Jacksonville, FL; and Behavioral Neurology (K.A.J.), Department of Neurology, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1212/WNL.0000000000005828DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059030PMC
July 2018

Non-right handed primary progressive apraxia of speech.

J Neurol Sci 2018 07 7;390:246-254. Epub 2018 May 7.

Department of Neurology (Behavioral Neurology), Mayo Clinic, Rochester, MN 55905, USA; Department of Neurology (Movement Disorders), Mayo Clinic, Rochester, MN 55905, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2018.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986290PMC
July 2018

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.

Authors:
Cyril Pottier Xiaolai Zhou Ralph B Perkerson Matt Baker Gregory D Jenkins Daniel J Serie Roberta Ghidoni Luisa Benussi Giuliano Binetti Adolfo López de Munain Miren Zulaica Fermin Moreno Isabelle Le Ber Florence Pasquier Didier Hannequin Raquel Sánchez-Valle Anna Antonell Albert Lladó Tammee M Parsons NiCole A Finch Elizabeth C Finger Carol F Lippa Edward D Huey Manuela Neumann Peter Heutink Matthis Synofzik Carlo Wilke Robert A Rissman Jaroslaw Slawek Emilia Sitek Peter Johannsen Jørgen E Nielsen Yingxue Ren Marka van Blitterswijk Mariely DeJesus-Hernandez Elizabeth Christopher Melissa E Murray Kevin F Bieniek Bret M Evers Camilla Ferrari Sara Rollinson Anna Richardson Elio Scarpini Giorgio G Fumagalli Alessandro Padovani John Hardy Parastoo Momeni Raffaele Ferrari Francesca Frangipane Raffaele Maletta Maria Anfossi Maura Gallo Leonard Petrucelli EunRan Suh Oscar L Lopez Tsz H Wong Jeroen G J van Rooij Harro Seelaar Simon Mead Richard J Caselli Eric M Reiman Marwan Noel Sabbagh Mads Kjolby Anders Nykjaer Anna M Karydas Adam L Boxer Lea T Grinberg Jordan Grafman Salvatore Spina Adrian Oblak M-Marsel Mesulam Sandra Weintraub Changiz Geula John R Hodges Olivier Piguet William S Brooks David J Irwin John Q Trojanowski Edward B Lee Keith A Josephs Joseph E Parisi Nilüfer Ertekin-Taner David S Knopman Benedetta Nacmias Irene Piaceri Silvia Bagnoli Sandro Sorbi Marla Gearing Jonathan Glass Thomas G Beach Sandra E Black Mario Masellis Ekaterina Rogaeva Jean-Paul Vonsattel Lawrence S Honig Julia Kofler Amalia C Bruni Julie Snowden David Mann Stuart Pickering-Brown Janine Diehl-Schmid Juliane Winkelmann Daniela Galimberti Caroline Graff Linn Öijerstedt Claire Troakes Safa Al-Sarraj Carlos Cruchaga Nigel J Cairns Jonathan D Rohrer Glenda M Halliday John B Kwok John C van Swieten Charles L White Bernardino Ghetti Jill R Murell Ian R A Mackenzie Ging-Yuek R Hsiung Barbara Borroni Giacomina Rossi Fabrizio Tagliavini Zbigniew K Wszolek Ronald C Petersen Eileen H Bigio Murray Grossman Vivianna M Van Deerlin William W Seeley Bruce L Miller Neill R Graff-Radford Bradley F Boeve Dennis W Dickson Joanna M Biernacka Rosa Rademakers

Lancet Neurol 2018 06 30;17(6):548-558. Epub 2018 Apr 30.

Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(18)30126-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237181PMC
June 2018

Molecular neuroimaging in primary progressive aphasia with predominant agraphia.

Neurocase 2018 04 23;24(2):121-123. Epub 2018 Mar 23.

a Department of Neurology , Mayo Clinic , Rochester , MN , USA.

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http://dx.doi.org/10.1080/13554794.2018.1454963DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101047PMC
April 2018

Rest in peace FTDP-17.

Authors:
Keith A Josephs

Brain 2018 02;141(2):324-331

Department of Neurology, Mayo Clinic, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1093/brain/awx367DOI Listing
February 2018

Tau-PET imaging with [18F]AV-1451 in primary progressive apraxia of speech.

Cortex 2018 02 2;99:358-374. Epub 2018 Jan 2.

Department of Neurology, Division of Behavioral Neurology, Mayo Clinic, Rochester, MN, USA; Department of Neurology, Division of Movement Disorders, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1016/j.cortex.2017.12.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800944PMC
February 2018

Predicting clinical decline in progressive agrammatic aphasia and apraxia of speech.

Neurology 2017 Nov 1;89(22):2271-2279. Epub 2017 Nov 1.

From the Department of Radiology (J.L.W., A.J.S., M.L.S., C.R.J.), Department of Health Sciences Research (Biostatistics) (S.D.W.), Department of Neurology (Speech Pathology) (J.R.D., H.M.C., E.A.S.), Department of Psychiatry & Psychology (Neuropsychology) (M.M.M.), Department of Information Technology (M.L.S.), and Department of Neurology (Behavioral Neurology and Movement Disorders) (K.A.J.), Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1212/WNL.0000000000004685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705252PMC
November 2017

Current Understanding of Neurodegenerative Diseases Associated With the Protein Tau.

Authors:
Keith A Josephs

Mayo Clin Proc 2017 08;92(8):1291-1303

Department of Neurology, Mayo Clinic, Rochester, MN. Electronic address:

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http://dx.doi.org/10.1016/j.mayocp.2017.04.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613938PMC
August 2017

IgLON5 antibody: Neurological accompaniments and outcomes in 20 patients.

Neurol Neuroimmunol Neuroinflamm 2017 Sep 18;4(5):e385. Epub 2017 Jul 18.

Department of Laboratory Medicine and Pathology (J.A.H., S.R.H., V.A.L., S.J.P., A.M.), Department of Neurology (K.A.J., E.K.S.L., N.K., A.G., V.A.L., S.J.P., A.M.), Department of Medicine (E.K.S.L.), Department of Immunology (V.A.L.), and Center for Sleep Medicine (E.K.S.L.), College of Medicine, Mayo Clinic, Rochester, MN; and Institute of Experimental Immunology (L.K., K.F., S.L.), Euroimmun AG, Lubeck, Germany.

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http://dx.doi.org/10.1212/NXI.0000000000000385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515599PMC
September 2017

Abnormal expression of homeobox genes and transthyretin in expansion carriers.

Neurol Genet 2017 Aug 7;3(4):e161. Epub 2017 Jun 7.

Department of Neuroscience (N.A.F., M.C.B., T.F.G., K.F.B., M.D.-H., P.H.B., J.C., K.R.J.-W., L.M.D., A.M.N., M.E.M., L.P., D.W.D., R.R., M.v.B.), Department of Health Sciences Research (X.W., Y.W.A.), Department of Neurology (N.R.G.-R., K.B.B.), Division of Biomedical Statistics and Informatics (M.G.H.), Mayo Clinic, Jacksonville, FL; Department of Neurology (J.W., M.B.), University of Miami, FL; Department of Neurology (K.A.J., J.E.P., D.S.K., R.C.P., B.F.B.), Mayo Clinic, Rochester, MN; and Divisions of Neurology and Neurobiology (R.B.), Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ.

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http://dx.doi.org/10.1212/NXG.0000000000000161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479438PMC
August 2017

A Neuropsychiatric Analysis of the Cotard Delusion.

J Neuropsychiatry Clin Neurosci 2018 23;30(1):58-65. Epub 2017 Jun 23.

From the Mayo Clinic School of Medicine, Rochester, Minn. (AS); and the Department of Neurology, Mayo Clinic, Rochester, Minn. (KAJ).

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http://dx.doi.org/10.1176/appi.neuropsych.17010018DOI Listing
August 2018