Keith A Hruska

Keith A Hruska

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Keith A Hruska

Publications by authors named "Keith A Hruska"

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New pathogenic insights inform therapeutic target development for renal osteodystrophy.

Kidney Int 2019 02;95(2):261-263

Department of Medicine Renal Division Washington University School of Medicine, Saint Louis, Missouri, USA; Department of Cell Biology, Washington University School of Medicine, Saint Louis, Missouri, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00852538183082
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http://dx.doi.org/10.1016/j.kint.2018.10.026DOI Listing
February 2019

Androgen exposure potentiates formation of intratubular communities and renal abscesses by Escherichia coli.

Kidney Int 2018 09 3;94(3):502-513. Epub 2018 Jul 3.

Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, USA; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2018.04.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109434PMC
September 2018

The activin receptor is stimulated in the skeleton, vasculature, heart, and kidney during chronic kidney disease.

Kidney Int 2018 01 23;93(1):147-158. Epub 2017 Aug 23.

Renal Division, Department of Pediatrics, Washington University School of Medicine, Saint Louis, Missouri, USA; Departments of Medicine and Cell Biology, Washington University School of Medicine, Saint Louis, Missouri, USA. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2017.06.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628245PMC
January 2018

Renal scar formation and kidney function following antibiotic-treated murine pyelonephritis.

Dis Model Mech 2017 11 7;10(11):1371-1379. Epub 2017 Sep 7.

Department of Pediatrics, Washington University School of Medicine, St Louis, MO 63110, USA

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http://dx.doi.org/10.1242/dmm.030130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719254PMC
November 2017

The chronic kidney disease - Mineral bone disorder (CKD-MBD): Advances in pathophysiology.

Bone 2017 Jul 22;100:80-86. Epub 2017 Jan 22.

Department of Pediatrics, Nephrology, Washington University Saint Louis, MO, United States.

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http://dx.doi.org/10.1016/j.bone.2017.01.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502716PMC
July 2017

Crosstalk between kidney and bone - Bench to bedside.

Bone 2017 07 11;100:1-3. Epub 2017 Apr 11.

Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA; Department of Physiology, University of Texas Southwestern Medical Center, Dallas, TX, USA; Charles and Jane Pak Center of Mineral Metabolism and Clinical Research, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1016/j.bone.2017.03.046DOI Listing
July 2017

Bone Mineral Density and Progression of Subclinical Atherosclerosis in African-Americans With Type 2 Diabetes.

J Clin Endocrinol Metab 2016 11 23;101(11):4135-4141. Epub 2016 Aug 23.

Division of Public Health Sciences (L.E.W., J.D., G.B.R., C.D.L.), Department of Pathology (T.C.R.), Department of Biochemistry (D.W.B., J.X.), and Department of Radiology (L.L.), Wake Forest School of Medicine, Winston-Salem, North Carolina; Division of Pediatric Nephrology (K.A.H.), Washington University School of Medicine, St. Louis, Missouri; Department of Radiology (J.J.C.), Vanderbilt University School of Medicine, Nashville, Tennessee; Department of Internal Medicine (B.I.F.), Section on Nephrology, Wake Forest School of Medicine, Winston-Salem, North Carolina.

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http://dx.doi.org/10.1210/jc.2016-1934DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095232PMC
November 2016

Androgens Enhance Male Urinary Tract Infection Severity in a New Model.

J Am Soc Nephrol 2016 06 8;27(6):1625-34. Epub 2015 Oct 8.

Department of Pediatrics, Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri

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http://dx.doi.org/10.1681/ASN.2015030327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884108PMC
June 2016

Ligand trap for the activin type IIA receptor protects against vascular disease and renal fibrosis in mice with chronic kidney disease.

Kidney Int 2016 06 11;89(6):1231-43. Epub 2016 Mar 11.

Department of Pediatrics, Renal Division, Washington University, St. Louis, Missouri, USA; Department of Cell Biology, Washington University, St. Louis, Missouri, USA; Department of Medicine, Washington University, St. Louis, Missouri, USA. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2016.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868771PMC
June 2016

The Kidney-Vascular-Bone Axis in the Chronic Kidney Disease-Mineral Bone Disorder.

Transplantation 2016 Mar;100(3):497-505

1 Division of Pediatric Nephrology, Department of Pediatrics, Southern Illinois University, Springfield, IL. 2 Division of Pediatric Nephrology, Department of Pediatrics, Washington University, St. Louis, MO.

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http://dx.doi.org/10.1097/TP.0000000000000903DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764429PMC
March 2016

SIRT6 deficiency culminates in low-turnover osteopenia.

Bone 2015 Dec 17;81:168-177. Epub 2015 Jul 17.

Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.bone.2015.07.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640951PMC
December 2015

Pathophysiology of the chronic kidney disease-mineral bone disorder.

Curr Opin Nephrol Hypertens 2015 Jul;24(4):303-9

aDepartment of Pediatrics, Nephrology bDepartments of Medicine and Cell Biology Washington University Saint Louis, Saint Louis, Missouri cDepartment of Pediatrics, Nephrology, Southern Illinois University, Springfield, Illinois, USA.

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http://dx.doi.org/10.1097/MNH.0000000000000132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699443PMC
July 2015

Clinical phenotype of APOL1 nephropathy in young relatives of patients with end-stage renal disease.

Pediatr Nephrol 2015 Jun 23;30(6):983-9. Epub 2014 Dec 23.

Department of Pediatrics (Pediatric Nephrology), Washington University School of Medicine, 5th Fl MPRB, 660 South Euclid Avenue, Campus Box 8208, St. Louis, MO, 63110, USA.

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http://dx.doi.org/10.1007/s00467-014-3031-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406792PMC
June 2015

Expression of DGCR8-dependent microRNAs is indispensable for osteoclastic development and bone-resorbing activity.

J Cell Biochem 2014 Jun;115(6):1043-7

Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, 63110, USA.

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http://dx.doi.org/10.1002/jcb.24759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079251PMC
June 2014

HDAC dependent transcriptional repression of Bmp-7 potentiates TGF-β mediated renal fibrosis in obstructive uropathy.

J Urol 2014 Jan 29;191(1):242-52. Epub 2013 Jun 29.

Division of Urology, Department of Surgery and Division of Pediatric Nephrology, Departments of Medicine and Pediatrics (KAH), Washington University, St. Louis Children's Hospital, St. Louis, Missouri. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2013.06.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084877PMC
January 2014

Early chronic kidney disease-mineral bone disorder stimulates vascular calcification.

Kidney Int 2014 Jan 24;85(1):142-50. Epub 2013 Jul 24.

Division of Pediatric Nephrology, Department of Pediatrics, Washington University, St Louis, Missouri, USA.

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http://dx.doi.org/10.1038/ki.2013.271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836911PMC
January 2014

Sclerostin is positively associated with bone mineral density in men and women and negatively associated with carotid calcified atherosclerotic plaque in men from the African American-Diabetes Heart Study.

J Clin Endocrinol Metab 2014 Jan 20;99(1):315-21. Epub 2013 Dec 20.

Departments of Pathology (T.C.R.), Public Health Sciences (J.D., L.E.W., C.D.L.), Radiology (T.C.R., J.J.C., R.C.H.), and Internal Medicine/Nephrology (B.I.F.) and Center for Genomics and Personalized Medicine Research (D.W.B., N.D.P., J.X., S.C.S.), Wake Forest School of Medicine, Winston-Salem, North Carolina 27157; and Department of Pediatric Nephrology (K.A.H., D.J.D.), Washington University School of Medicine, St Louis, Missouri 63110.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2013-3168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879670PMC
January 2014

Down-regulation of miR-21 biogenesis by estrogen action contributes to osteoclastic apoptosis.

J Cell Biochem 2013 Jun;114(6):1217-22

Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1002/jcb.24471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154486PMC
June 2013

Relationships between serum MCP-1 and subclinical kidney disease: African American-Diabetes Heart Study.

BMC Nephrol 2012 Nov 14;13:148. Epub 2012 Nov 14.

Department of Internal Medicine/Nephrology, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC, 27157-1053, USA.

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http://dx.doi.org/10.1186/1471-2369-13-148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534523PMC
November 2012

Endogenous BMP-7 is a critical molecular determinant of the reversibility of obstruction-induced renal injuries.

Am J Physiol Renal Physiol 2011 Dec 31;301(6):F1293-302. Epub 2011 Aug 31.

Department of Surgery, Division of Pediatric Urology, Washington University, 4990 Children's Place, St. Louis, MO 63110, USA.

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http://www.physiology.org/doi/10.1152/ajprenal.00071.2011
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http://dx.doi.org/10.1152/ajprenal.00071.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774217PMC
December 2011

RGS4, a GTPase activator, improves renal function in ischemia-reperfusion injury.

Kidney Int 2011 Aug 16;80(3):263-71. Epub 2011 Mar 16.

Nephrology Division, John Milliken Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri, USA.

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http://dx.doi.org/10.1038/ki.2011.63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221244PMC
August 2011

The BMP-7-Smad1/5/8 pathway promotes kidney repair after obstruction induced renal injury.

J Urol 2011 Jun 27;185(6 Suppl):2523-30. Epub 2011 Apr 27.

Division of Pediatric Urology, Department of Surgery, Washington University, St. Louis Children's Hospital, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1016/j.juro.2011.01.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418146PMC
June 2011

A microRNA expression signature of osteoclastogenesis.

Blood 2011 Mar 27;117(13):3648-57. Epub 2011 Jan 27.

Department of Pediatrics, Washington University School of Medicine, 660 S. Euclid Avenue, St Louis, MO 63110, USA.

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http://dx.doi.org/10.1182/blood-2010-10-311415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072882PMC
March 2011

The roles of the skeleton and phosphorus in the CKD mineral bone disorder.

Adv Chronic Kidney Dis 2011 Mar;18(2):98-104

Division of Pediatric Nephrology, Department of Pediatrics, Washington University, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1053/j.ackd.2011.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103992PMC
March 2011

Cardiovascular risk in chronic kidney disease (CKD): the CKD-mineral bone disorder (CKD-MBD).

Pediatr Nephrol 2010 Apr 7;25(4):769-78. Epub 2009 Nov 7.

Division of Pediatric Nephrology, Washington University, St. Louis, MO, USA.

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http://dx.doi.org/10.1007/s00467-009-1337-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719392PMC
April 2010

Bone morphogenetic protein 7 (BMP7) gene polymorphisms are associated with inverse relationships between vascular calcification and BMD: the Diabetes Heart Study.

J Bone Miner Res 2009 Oct;24(10):1719-27

Department of Internal Medicine, Section on Nephrology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1053, USA.

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http://dx.doi.org/10.1359/jbmr.090501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743282PMC
October 2009

CKD accelerates development of neointimal hyperplasia in arteriovenous fistulas.

J Am Soc Nephrol 2009 Jun 7;20(6):1236-45. Epub 2009 May 7.

Department of Cardiovascular Surgery, Asahikawa Medical University, Hokkaido, Japan.

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http://dx.doi.org/10.1681/ASN.2007121312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689906PMC
June 2009

The pathogenesis of vascular calcification in the chronic kidney disease mineral bone disorder: the links between bone and the vasculature.

Semin Nephrol 2009 Mar;29(2):156-65

Department of Pediatrics, Division of Nephrology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.semnephrol.2009.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758096PMC
March 2009

Impaired micro-RNA pathways diminish osteoclast differentiation and function.

J Biol Chem 2009 Feb 5;284(7):4667-78. Epub 2008 Dec 5.

Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1074/jbc.M805777200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640963PMC
February 2009

Vitamin D receptor activators can protect against vascular calcification.

J Am Soc Nephrol 2008 Aug 30;19(8):1509-19. Epub 2008 Apr 30.

Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1681/ASN.2007080902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2488263PMC
August 2008

Hyperphosphatemia of chronic kidney disease.

Kidney Int 2008 Jul 30;74(2):148-57. Epub 2008 Apr 30.

Department of Pediatrics, Renal Division, Washington University, St Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1038/ki.2008.130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735026PMC
July 2008

The mechanism of phosphorus as a cardiovascular risk factor in CKD.

J Am Soc Nephrol 2008 Jun 16;19(6):1092-105. Epub 2008 Apr 16.

Department of Pediatrics, Washington University, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1681/ASN.2007070760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396927PMC
June 2008

Osteoporosis and cardiovascular disease: lessons from chronic kidney disease.

Clin Cases Miner Bone Metab 2008 Jan;5(1):35-9

Renal Divisions, Departments of Pediatrics and.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781186PMC
January 2008

Bone morphogenetic protein-7 delays podocyte injury due to high glucose.

Nephrol Dial Transplant 2007 Dec 8;22(12):3442-50. Epub 2007 Aug 8.

Department of Pediatrics, Washington University, Saint Louis, MO 63110-1093, USA.

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http://dx.doi.org/10.1093/ndt/gfm503DOI Listing
December 2007

Renal osteodystrophy, phosphate homeostasis, and vascular calcification.

Semin Dial 2007 Jul-Aug;20(4):309-15

Renal Division, Departments of Pediatrics and Medicine, Washington University, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1111/j.1525-139X.2007.00300.xDOI Listing
October 2007

Reversal of the adynamic bone disorder and decreased vascular calcification in chronic kidney disease by sevelamer carbonate therapy.

J Am Soc Nephrol 2007 Jan 20;18(1):122-30. Epub 2006 Dec 20.

Renal Division, Department of Pediatrics, Washington University School of Medicien, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1681/ASN.2006050490DOI Listing
January 2007

New discoveries in the pathogenesis of renal osteodystrophy.

J Bone Miner Metab 2006 ;24(2):169-71

Department of Medicine, Creighton University, Omaha, NE 68131, USA.

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http://dx.doi.org/10.1007/s00774-005-0666-8DOI Listing
June 2006

Connections between vascular calcification and progression of chronic kidney disease: therapeutic alternatives.

Kidney Int Suppl 2005 Dec(99):S142-51

Washington University School of Medicine, Renal Division, Department of Pediatrics, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1111/j.1523-1755.2005.09926.xDOI Listing
December 2005

Wnt-dependent beta-catenin signaling is activated after unilateral ureteral obstruction, and recombinant secreted frizzled-related protein 4 alters the progression of renal fibrosis.

J Am Soc Nephrol 2005 Aug 8;16(8):2373-84. Epub 2005 Jun 8.

Department of Pediatrics, Washington University School of Medicine, 5th Floor MPRB, Campus Box 8208, 660 South Euclid Avenue, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1681/ASN.2004110949DOI Listing
August 2005

Bone morphogenetic proteins in vascular calcification.

Circ Res 2005 Jul;97(2):105-14

Renal Division, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA.

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https://www.ahajournals.org/doi/10.1161/01.RES.00000175571.5
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http://dx.doi.org/10.1161/01.RES.00000175571.53833.6cDOI Listing
July 2005

Low turnover osteodystrophy and vascular calcification are amenable to skeletal anabolism in an animal model of chronic kidney disease and the metabolic syndrome.

J Am Soc Nephrol 2005 Apr 2;16(4):917-28. Epub 2005 Mar 2.

Department of Medicine, Washington University School of Medicine, Campus Box 8208, 5th Floor MPRB, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1681/ASN.2004100835DOI Listing
April 2005

Akt1/Akt2 and mammalian target of rapamycin/Bim play critical roles in osteoclast differentiation and survival, respectively, whereas Akt is dispensable for cell survival in isolated osteoclast precursors.

J Biol Chem 2005 Feb 15;280(5):3583-9. Epub 2004 Nov 15.

Department of Pediatrics, Cell and Molecular Biology Unit, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1074/jbc.M410480200DOI Listing
February 2005

In vivo transplantation of neonatal ovine neocartilage allografts: determining the effectiveness of tissue transglutaminase.

J Knee Surg 2005 Jan;18(1):31-42

School of Veterinary Medicine, University of Wisconsin-Madison, Wisc 53706-1102, USA.

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January 2005

Bone morphogenetic protein 7: a novel treatment for chronic renal and bone disease.

Curr Opin Nephrol Hypertens 2004 Jul;13(4):417-22

Department of Medicine, Washington University School of Medicine, St Louis, Missouri, USA.

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July 2004

Polyphosphoinositides-dependent regulation of the osteoclast actin cytoskeleton and bone resorption.

BMC Cell Biol 2004 May 13;5:19. Epub 2004 May 13.

Department of Biomedical Sciences, University of Maryland, Baltimore, Maryland 21201, USA.

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http://bmccellbiol.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2121-5-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC441372PMC
May 2004

Successful treatment of an adynamic bone disorder with bone morphogenetic protein-7 in a renal ablation model.

J Am Soc Nephrol 2004 Feb;15(2):359-69

Renal Division, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1097/01.asn.0000109671.99498.08DOI Listing
February 2004

Kidney-bone, bone-kidney, and cell-cell communications in renal osteodystrophy.

Semin Nephrol 2004 Jan;24(1):25-38

Department of Pediatrics, Washington University School of Medicine, St Louis, MO 63110, USA.

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January 2004

Adenovirus mediated BMP-13 gene transfer induces chondrogenic differentiation of murine mesenchymal progenitor cells.

J Bone Miner Res 2004 Jan;19(1):111-22

Department of Orthopaedic Surgery and Division of Renal Diseases, Washington University School of Medicine, St Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1359/jbmr.2004.19.1.111DOI Listing
January 2004

Rho-dependent Rho kinase activation increases CD44 surface expression and bone resorption in osteoclasts.

J Biol Chem 2003 Aug 1;278(31):29086-97. Epub 2003 May 1.

Department of Oral Craniofacial Biological Sciences, University of Maryland, Baltimore, Maryland 21201, USA.

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http://dx.doi.org/10.1074/jbc.M211074200DOI Listing
August 2003

Bone morphogenic protein-7 (BMP-7), a novel therapy for diabetic nephropathy.

Kidney Int 2003 Jun;63(6):2037-49

Renal Division, Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S008525381549121
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http://dx.doi.org/10.1046/j.1523-1755.2003.00035.xDOI Listing
June 2003

BMP-7 is an efficacious treatment of vascular calcification in a murine model of atherosclerosis and chronic renal failure.

J Am Soc Nephrol 2003 Jun;14(6):1559-67

Renal Division, Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1097/01.asn.0000068404.57780.ddDOI Listing
June 2003

The urinary response to an oral oxalate load in recurrent calcium stone formers.

J Urol 2003 Jun;169(6):2030-3

Department of Surgery (Urology), University of Colorado Health Sciences Center, Denver, Colorado, USA.

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http://dx.doi.org/10.1097/01.ju.0000062527.37579.49DOI Listing
June 2003

The pathogenesis of osteodystrophy after renal transplantation as detected by early alterations in bone remodeling.

Kidney Int 2003 May;63(5):1915-23

Centro Nacional de Diálisis y Trasplante, Division of Nephrology, Hospital Universitario de Caracas, Venezuela.

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http://dx.doi.org/10.1046/j.1523-1755.2003.00938.xDOI Listing
May 2003

Inhibition of cell survival signal protein kinase B/Akt by curcumin in human prostate cancer cells.

J Cell Biochem 2003 May;89(1):1-5

Department of Pediatrics, Cell & Molecular Biology Unit, Washington University School of Medicine, MPRB, 660 S. Euclid Ave, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1002/jcb.10495DOI Listing
May 2003

Leupaxin is a critical adaptor protein in the adhesion zone of the osteoclast.

J Bone Miner Res 2003 Apr;18(4):669-85

Department of Oral and Craniofacial Biological Sciences, University of Maryland, Baltimore, Maryland 21201-1586, USA.

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http://dx.doi.org/10.1359/jbmr.2003.18.4.669DOI Listing
April 2003

PTEN regulates RANKL- and osteopontin-stimulated signal transduction during osteoclast differentiation and cell motility.

J Biol Chem 2003 Feb 30;278(7):5001-8. Epub 2002 Nov 30.

Department of Pediatrics, Cell and Molecular Biology Unit, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1074/jbc.M209299200DOI Listing
February 2003

Proprotein convertases regulate activity of prostate epithelial cell differentiation markers and are modulated in human prostate cancer cells.

J Cell Biochem 2003 Feb;88(2):394-9

Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri 63100, USA.

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http://dx.doi.org/10.1002/jcb.10327DOI Listing
February 2003

Treatment of chronic tubulointerstitial disease: a new concept.

Authors:
Keith A Hruska

Kidney Int 2002 May;61(5):1911-22

Barnes-Jewish Hospital at Washington University, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1046/j.1523-1755.2002.00331.xDOI Listing
May 2002

Treatment of a murine model of high-turnover renal osteodystrophy by exogenous BMP-7.

Kidney Int 2002 Apr;61(4):1322-31

Division of Nephrology, Saint Louis University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1046/j.1523-1755.2002.00258.xDOI Listing
April 2002

Bone morphogenetic protein-7: an anti-fibrotic morphogenetic protein with therapeutic importance in renal disease.

Curr Opin Nephrol Hypertens 2002 Jan;11(1):31-6

Department of Medicine, Children's and Barnes-Jewish Hospitals, Washington University School of Medicine, St Louis, Missouri 63110, USA.

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January 2002