Publications by authors named "Keith A Ching"

18Publications

Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling.

Cell Rep 2020 02;30(6):1935-1950.e8

Tumor Cell Biology, Pfizer Oncology Research & Development, La Jolla, Pfizer Inc., 10777 Science Center Drive, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/j.celrep.2020.01.054DOI Listing
February 2020

Cell Index Database (CELLX): a web tool for cancer precision medicine.

Pac Symp Biocomput 2015 :10-9

Oncology Research Unit, Pfizer Global Research & Development, Pfizer Inc., 10777 Science Center Drive San Diego, CA 92121, USA.

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April 2016

Molecular predictors of sensitivity to the insulin-like growth factor 1 receptor inhibitor Figitumumab (CP-751,871).

Mol Cancer Ther 2013 Dec 9;12(12):2929-39. Epub 2013 Oct 9.

Corresponding Author: James G. Christensen, Mirati Therapeutics, 9363 Towne Center Drive, Suite 200, San Diego, CA 92121.

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http://dx.doi.org/10.1158/1535-7163.MCT-13-0442-TDOI Listing
December 2013

An integrated genomic approach to identify predictive biomarkers of response to the aurora kinase inhibitor PF-03814735.

Mol Cancer Ther 2012 Mar 5;11(3):710-9. Epub 2012 Jan 5.

Translational Research, Oncology Research Unit, Pfizer Global R&D, 10777 Science Center Dr. (CB4), San Diego, CA 92121, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-11-0184DOI Listing
March 2012

Evaluation of the antitumor effects and mechanisms of PF00299804, a pan-HER inhibitor, alone or in combination with chemotherapy or targeted agents in gastric cancer.

Mol Cancer Ther 2012 Feb 1;11(2):439-51. Epub 2011 Dec 1.

Cancer Research Institute, Seoul National University Hospital, Seoul National University College of Medicine, Jongno-gu, Seoul, 110-744, Korea.

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http://dx.doi.org/10.1158/1535-7163.MCT-11-0494DOI Listing
February 2012

Analysis of the vertebrate insulator protein CTCF-binding sites in the human genome.

Cell 2007 Mar;128(6):1231-45

Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine, La Jolla, CA 92093-0653, USA.

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http://dx.doi.org/10.1016/j.cell.2006.12.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572726PMC
March 2007

Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome.

Nat Genet 2007 Mar 4;39(3):311-8. Epub 2007 Feb 4.

Ludwig Institute for Cancer Research, University of California San Diego (UCSD) School of Medicine, 9500 Gilman Drive, La Jolla, California 92093-0653 USA.

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http://dx.doi.org/10.1038/ng1966DOI Listing
March 2007

Inducible T cell tyrosine kinase (ITK): structural requirements and actin polymerization.

Adv Exp Med Biol 2006 ;584:29-41

Department of Biology and the Center for Microbial Sciences, San Diego State University, San Diego, CA 92181, USA

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http://dx.doi.org/10.1007/0-387-34132-3_3DOI Listing
October 2006

Data and animal management software for large-scale phenotype screening.

Mamm Genome 2006 Apr 4;17(4):288-97. Epub 2006 Apr 4.

Genomics Institute, Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, USA.

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http://link.springer.com/10.1007/s00335-005-0145-5
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http://dx.doi.org/10.1007/s00335-005-0145-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1428800PMC
April 2006

Ubiquitin-mediated sequestration of normal cellular proteins into polyglutamine aggregates.

Proc Natl Acad Sci U S A 2003 Jul 11;100(15):8892-7. Epub 2003 Jul 11.

Department of Cancer and Cell Biology, Genomics Institute of the Novartis Research Foundation (GNF), 10675 John J. Hopkins Drive, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1073/pnas.1530212100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC166409PMC
July 2003