Publications by authors named "Keith A Boroevich"

36Publications

Analyses of non-coding somatic drivers in 2,658 cancer whole genomes.

Nature 2020 02 5;578(7793):102-111. Epub 2020 Feb 5.

The Broad Institute of MIT and Harvard, Cambridge, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41586-020-1965-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054214PMC
February 2020

Quantification of multicellular colonization in tumor metastasis using exome-sequencing data.

Int J Cancer 2020 05 15;146(9):2488-2497. Epub 2020 Feb 15.

Department of Medical Science Mathematics, Medical Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ijc.32910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079087PMC
May 2020

A comparison of machine learning classifiers for dementia with Lewy bodies using miRNA expression data.

BMC Med Genomics 2019 10 30;12(1):150. Epub 2019 Oct 30.

Laboratory Chief, Division of Genomic Medicine, Medical Genome Center, National Center for Geriatrics and Gerontology, 7-430 Morioka-cho, Obu, Aichi, 474-8511, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12920-019-0607-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822471PMC
October 2019

DeepInsight: A methodology to transform a non-image data to an image for convolution neural network architecture.

Sci Rep 2019 08 6;9(1):11399. Epub 2019 Aug 6.

Laboratory for Medical Science Mathematics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-019-47765-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684600PMC
August 2019

An integrative machine learning approach for prediction of toxicity-related drug safety.

Life Sci Alliance 2018 Dec 28;1(6):e201800098. Epub 2018 Nov 28.

Laboratory for Medical Science Mathematics, Rikagaku Kenkyūjyo Center for Integrative Medical Sciences, Tsurumi, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.26508/lsa.201800098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262234PMC
December 2018

A novel homozygous missense mutation in the SH3-binding motif of STAMBP causing microcephaly-capillary malformation syndrome.

J Hum Genet 2018 Sep 15;63(9):957-963. Epub 2018 Jun 15.

Department of Pediatrics and Neonatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s10038-018-0482-3DOI Listing
September 2018

A novel genetic syndrome with STARD9 mutation and abnormal spindle morphology.

Am J Med Genet A 2017 Oct 4;173(10):2690-2696. Epub 2017 Aug 4.

National Institute of Genetics, Department of Molecular Genetics, Division of Centrosome Biology, Mishima, Shizuoka, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajmg.a.38391DOI Listing
October 2017

The prediction models for postoperative overall survival and disease-free survival in patients with breast cancer.

Cancer Med 2017 Jul 24;6(7):1627-1638. Epub 2017 May 24.

Department of Medical Science Mathematics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cam4.1092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504310PMC
July 2017

Stepwise iterative maximum likelihood clustering approach.

BMC Bioinformatics 2016 Aug 24;17(1):319. Epub 2016 Aug 24.

RIKEN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12859-016-1184-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995791PMC
August 2016

Systematic analysis of mutation distribution in three dimensional protein structures identifies cancer driver genes.

Sci Rep 2016 05 26;6:26483. Epub 2016 May 26.

Laboratory for Genome Sequencing Analysis, RIKEN Center for Integrative Medical Sciences, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep26483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880911PMC
May 2016

Hierarchical Maximum Likelihood Clustering Approach.

IEEE Trans Biomed Eng 2017 01 24;64(1):112-122. Epub 2016 Mar 24.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1109/TBME.2016.2542212DOI Listing
January 2017

Gene expression profiling of DBA/2J mice cochleae treated with l-methionine and valproic acid.

Genom Data 2015 Sep 2;5:323-5. Epub 2015 Jul 2.

Laboratory for Medical Science Mathematics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gdata.2015.06.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583681PMC
September 2015

Performance comparison of four commercial human whole-exome capture platforms.

Sci Rep 2015 Aug 3;5:12742. Epub 2015 Aug 3.

Laboratory for Medical Science Mathematics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep12742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522667PMC
August 2015

Genomic organization and evolution of the Atlantic salmon hemoglobin repertoire.

BMC Genomics 2010 Oct 5;11:539. Epub 2010 Oct 5.

Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2164-11-539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091688PMC
October 2010

Comparative genomics identifies candidate genes for infectious salmon anemia (ISA) resistance in Atlantic salmon (Salmo salar).

Mar Biotechnol (NY) 2011 Apr 16;13(2):232-41. Epub 2010 Apr 16.

Department of Molecular Biology and Biochemistry, Simon Fraser University, 8888 University Drive, Burnaby, BC, Canada V5A 1S6.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10126-010-9284-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084937PMC
April 2011

Piecing together a ciliome.

Trends Genet 2006 Sep 24;22(9):491-500. Epub 2006 Jul 24.

Department of Molecular Biology and Biochemistry, Simon Fraser University, 8888 University Dr., Burnaby, BC V5A 1S6, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tig.2006.07.006DOI Listing
September 2006

Functional genomics of the cilium, a sensory organelle.

Curr Biol 2005 May;15(10):935-41

Department of Molecular Biology and Biochemistry, Simon Fraser University, 8888 University Drive, Burnaby, British Columbia V5A 1S6, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cub.2005.04.059DOI Listing
May 2005