Keisuke Kuida

Keisuke Kuida

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Keisuke Kuida

Keisuke Kuida

Publications by authors named "Keisuke Kuida"

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An inhibitor of apoptosis protein antagonist T-3256336 potentiates the antitumor efficacy of the Nedd8-activating enzyme inhibitor pevonedistat (TAK-924/MLN4924).

Biochem Biophys Res Commun 2016 Nov 19;480(3):380-386. Epub 2016 Oct 19.

Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd., 26-1, Muraoka-higashi, 2-Chome, Fujisawa, Kanagawa, 251-8555, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.10.058DOI Listing
November 2016

Local apoptosis modulates early mammalian brain development through the elimination of morphogen-producing cells.

Dev Cell 2013 Dec;27(6):621-34

Department of Genetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan; Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Chiyoda-ku, Tokyo 102-0075, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2013.11.015DOI Listing
December 2013

Live imaging of apoptosis in a novel transgenic mouse highlights its role in neural tube closure.

J Cell Biol 2011 Dec;195(6):1047-60

Department of Genetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.

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http://dx.doi.org/10.1083/jcb.201104057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241723PMC
December 2011

Maturation of the olfactory sensory neurons by Apaf-1/caspase-9-mediated caspase activity.

Proc Natl Acad Sci U S A 2010 Jul 12;107(30):13366-71. Epub 2010 Jul 12.

Department of Genetics, Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo 113-0033, Japan.

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http://dx.doi.org/10.1073/pnas.0910488107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922127PMC
July 2010

Decreased retinal neuronal cell death in caspase-1 knockout mice.

Jpn J Ophthalmol 2006 Sep-Oct;50(5):417-425

Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1007/s10384-006-0352-yDOI Listing
November 2006

Caspases 3 and 7: key mediators of mitochondrial events of apoptosis.

Science 2006 Feb;311(5762):847-51

Section of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1126/science.1115035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738210PMC
February 2006

Notch promotes survival of neural precursor cells via mechanisms distinct from those regulating neurogenesis.

Dev Biol 2004 Dec;276(1):172-84

Institute of Molecular and Cellular Biosciences, University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan.

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http://dx.doi.org/10.1016/j.ydbio.2004.08.039DOI Listing
December 2004

Functions of MAP kinases: insights from gene-targeting studies.

J Biochem 2004 Jun;135(6):653-6

Vertex Pharmaceuticals, 130 Waverly Street, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1093/jb/mvh078DOI Listing
June 2004

Inhibitors of protein kinase signaling pathways: emerging therapies for cardiovascular disease.

Circulation 2004 Mar;109(10):1196-205

Molecular Cardiology Research Institute, Tufts-New England Medical Center and Tufts University School of Medicine, Boston, Mass 02111, USA.

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http://dx.doi.org/10.1161/01.CIR.0000118538.21306.A9DOI Listing
March 2004

Amyloid beta peptide-induced cerebral neuronal loss is mediated by caspase-3 in vivo.

J Neuropathol Exp Neurol 2004 Mar;63(3):255-61

Department of Neuroscience, Graduate School of Medicine, Osaka City University, Osaka, Japan.

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http://dx.doi.org/10.1093/jnen/63.3.255DOI Listing
March 2004

Roles of caspase-1 in Listeria infection in mice.

Int Immunol 2004 Feb;16(2):335-43

Section of Immunobiology, Yale University School of Medicine and Howard Hughes Medical Institute, New Haven, CT 06510, USA.

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http://dx.doi.org/10.1093/intimm/dxh041DOI Listing
February 2004

Extracellular signal-regulated kinase 2 is necessary for mesoderm differentiation.

Proc Natl Acad Sci U S A 2003 Oct 17;100(22):12759-64. Epub 2003 Oct 17.

Department of Biology, Vertex Pharmaceuticals, 130 Waverly Street, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1073/pnas.2134254100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC240691PMC
October 2003

Erk5 null mice display multiple extraembryonic vascular and embryonic cardiovascular defects.

Proc Natl Acad Sci U S A 2002 Jul 1;99(14):9248-53. Epub 2002 Jul 1.

Vertex Pharmaceuticals, Department of Biology, 130 Waverly Street, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1073/pnas.142293999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC123126PMC
July 2002

Polyglutamine aggregates stimulate ER stress signals and caspase-12 activation.

Hum Mol Genet 2002 Jun;11(13):1505-15

Division of Development and Differentiation, National Institute of Neuroscience, 4-1-1 Ogawahigashi-machi, Kodaira, Tokyo 187-8502, Japan.

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http://dx.doi.org/10.1093/hmg/11.13.1505DOI Listing
June 2002