Keiko Nakayama

Keiko Nakayama

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Keiko Nakayama

Publications by authors named "Keiko Nakayama"

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Knockout Mouse Models Provide Insight into the Biological Functions of CRL1 Components.

Adv Exp Med Biol 2020 ;1217:147-171

Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1007/978-981-15-1025-0_10DOI Listing
February 2020

Study profile of The Tohoku Medical Megabank Community-Based Cohort Study.

J Epidemiol 2020 Jan 11. Epub 2020 Jan 11.

Tohoku Medical Megabank Organization, Tohoku University.

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http://dx.doi.org/10.2188/jea.JE20190271DOI Listing
January 2020

Pathogenic mutations in the ALS gene CCNF cause cytoplasmic mislocalization of Cyclin F and elevated VCP ATPase activity.

Hum Mol Genet 2019 10;28(20):3486-3497

Division of Cell Proliferation, ART, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan.

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http://dx.doi.org/10.1093/hmg/ddz119DOI Listing
October 2019

Detection of NRAS mutation in cell-free DNA biological fluids from patients with kaposiform lymphangiomatosis.

Orphanet J Rare Dis 2019 09 11;14(1):215. Epub 2019 Sep 11.

Department of Pediatrics, Graduate School of Medicine, Gifu University, Yanagido 1-1, Gifu, 501-1194, Japan.

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http://dx.doi.org/10.1186/s13023-019-1191-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737666PMC
September 2019

The ubiquitin ligase subunit β-TrCP in Sertoli cells is essential for spermatogenesis in mice.

Dev Biol 2019 01 2;445(2):178-188. Epub 2018 Nov 2.

Division of Cell Proliferation, ART, Graduate School of Medicine, Tohoku University, Sendai, Miyagi 980-8575, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00121606183015
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http://dx.doi.org/10.1016/j.ydbio.2018.10.023DOI Listing
January 2019

Novel IARS2 mutations in Japanese siblings with CAGSSS, Leigh, and West syndrome.

Brain Dev 2018 Nov 2;40(10):934-938. Epub 2018 Jul 2.

Department of Pediatrics, Tohoku University School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.

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http://dx.doi.org/10.1016/j.braindev.2018.06.010DOI Listing
November 2018

Bone marrow PDGFRα+Sca-1+-enriched mesenchymal stem cells support survival of and antibody production by plasma cells in vitro through IL-6.

Int Immunol 2018 05;30(6):241-253

Department of Experimental Immunology, Institute of Development, Aging and Cancer, Tohoku University, Seiryo-machi, Sendai, Japan.

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http://dx.doi.org/10.1093/intimm/dxy018DOI Listing
May 2018

Bach2 Promotes B Cell Receptor-Induced Proliferation of B Lymphocytes and Represses Cyclin-Dependent Kinase Inhibitors.

J Immunol 2018 04 14;200(8):2882-2893. Epub 2018 Mar 14.

Department of Biochemistry, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan;

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http://dx.doi.org/10.4049/jimmunol.1601863DOI Listing
April 2018

Transforming Growth Factor β-Induced Proliferative Arrest Mediated by TRIM26-Dependent TAF7 Degradation and Its Antagonism by MYC.

Mol Cell Biol 2018 03 12;38(5). Epub 2018 Feb 12.

Division of Cell Proliferation, ART, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan

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http://dx.doi.org/10.1128/MCB.00449-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809684PMC
March 2018

Glucose deprivation induces primary cilium formation through mTORC1 inactivation.

J Cell Sci 2018 01 8;131(1). Epub 2018 Jan 8.

Department of Biomolecular Sciences, Graduate School of Life Sciences, Tohoku University, Sendai, Miyagi 980-8578, Japan

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http://dx.doi.org/10.1242/jcs.208769DOI Listing
January 2018

Inferring evolutionary responses of Anolis carolinensis introduced into the Ogasawara archipelago using whole genome sequence data.

Sci Rep 2017 12 21;7(1):18008. Epub 2017 Dec 21.

Department of Ecology and Evolutionary Biology, Graduate School of Life Sciences, Tohoku University, Aoba-ku, Sendai, 980-8578, Japan.

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http://dx.doi.org/10.1038/s41598-017-17852-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740155PMC
December 2017

Regulation of mitosis-meiosis transition by the ubiquitin ligase β-TrCP in male germ cells.

Development 2017 11 5;144(22):4137-4147. Epub 2017 Oct 5.

Division of Cell Proliferation, ART, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan

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http://dx.doi.org/10.1242/dev.158485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719248PMC
November 2017

Long-term outcome of a 26-year-old woman with West syndrome and an nuclear receptor subfamily 2 group F member 1 gene (NR2F1) mutation.

Seizure 2017 Aug 20;50:144-146. Epub 2017 Jun 20.

Department of Pediatrics, Tohoku University School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.seizure.2017.06.018DOI Listing
August 2017

Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2.

Cancer Cell 2017 05;31(5):669-684.e7

State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, Fujian 361102, China. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863541PMC
May 2017

Geminin is an indispensable inhibitor of Cdt1 in mouse embryonic stem cells.

Genes Cells 2017 Apr 14;22(4):360-375. Epub 2017 Mar 14.

Department of Cell Proliferation, United Center for Advanced Research and Translational Medicine, Graduate School of Medicine, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan.

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http://dx.doi.org/10.1111/gtc.12482DOI Listing
April 2017

Protein-arginine deiminase 2 suppresses proliferation of colon cancer cells through protein citrullination.

Cancer Sci 2017 Apr 12;108(4):713-718. Epub 2017 Apr 12.

Department of Cell Proliferation, United Centers for Advanced Research and Translational Medicine, ART, Graduate School of Medicine, Tohoku University, Sendai, Japan.

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http://dx.doi.org/10.1111/cas.13179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406534PMC
April 2017

A large-scale targeted proteomics assay resource based on an in vitro human proteome.

Nat Methods 2017 03 26;14(3):251-258. Epub 2016 Dec 26.

Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1038/nmeth.4116DOI Listing
March 2017

A Bach2-Cebp Gene Regulatory Network for the Commitment of Multipotent Hematopoietic Progenitors.

Cell Rep 2017 03;18(10):2401-2414

Department of Biochemistry, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan; AMED-CREST, Japan Agency for Medical Research and Development, Tokyo 100-0004, Japan; Center for Regulatory Epigenome and Diseases, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.02.029DOI Listing
March 2017

Ubiquitylation of Ku80 by RNF126 Promotes Completion of Nonhomologous End Joining-Mediated DNA Repair.

Mol Cell Biol 2017 02 1;37(4). Epub 2017 Feb 1.

Division of Cell Proliferation, ART, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan

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http://dx.doi.org/10.1128/MCB.00347-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288581PMC
February 2017

The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin.

Nat Immunol 2017 01 21;18(1):64-73. Epub 2016 Nov 21.

Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan.

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http://dx.doi.org/10.1038/ni.3614DOI Listing
January 2017

The double knockout of Bach1 and Bach2 in mice reveals shared compensatory mechanisms in regulating alveolar macrophage function and lung surfactant homeostasis.

J Biochem 2016 Dec 7;160(6):333-344. Epub 2016 Jul 7.

Department of Biochemistry, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan

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http://dx.doi.org/10.1093/jb/mvw041DOI Listing
December 2016

Wnt-β-catenin signaling regulates ABCC3 (MRP3) transporter expression in colorectal cancer.

Cancer Sci 2016 Dec 13;107(12):1776-1784. Epub 2016 Dec 13.

Department of Cell Proliferation, ART, Graduate School of Medicine, Tohoku University, Aoba-ku, Sendai, Japan.

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http://dx.doi.org/10.1111/cas.13097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198960PMC
December 2016

[Primary Spontaneous Pneumothorax with an Azygos Lobe].

Kyobu Geka 2016 Nov;69(12):1017-1019

Department of Thoracic Surgery, Itami City Hospital, Itami, Japan.

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November 2016

Lack of genetic variation prevents adaptation at the geographic range margin in a damselfly.

Mol Ecol 2016 09 26;25(18):4450-60. Epub 2016 Aug 26.

Division of Ecology and Evolutionary Biology, Graduate School of Life Sciences, Tohoku University, 6-3 Aoba, Aramaki, Aoba, Sendai, Miyagi, 980-8578, Japan.

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http://dx.doi.org/10.1111/mec.13782DOI Listing
September 2016

Lack of Transcription Triggers H3K27me3 Accumulation in the Gene Body.

Cell Rep 2016 07 7;16(3):696-706. Epub 2016 Jul 7.

Department of Cell Proliferation, United Center for Advanced Research and Translational Medicine, Graduate School of Medicine, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.06.034DOI Listing
July 2016

Genomewide approaches for BACH1 target genes in mouse embryonic fibroblasts showed BACH1-Pparg pathway in adipogenesis.

Genes Cells 2016 Jun 30;21(6):553-67. Epub 2016 Mar 30.

Department of Biochemistry, Tohoku University Graduate School of Medicine, 2-1, Seiryo-machi, Aoba-ku, Sendai, 980-8575, Japan.

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http://dx.doi.org/10.1111/gtc.12365DOI Listing
June 2016

Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription.

Nat Commun 2016 05 23;7:11624. Epub 2016 May 23.

Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.

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http://dx.doi.org/10.1038/ncomms11624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879264PMC
May 2016

A Case of Superior Mesenteric Artery Occlusion Caused by Delayed Administration of Anticoagulants in a Patient with Nonvalvular Atrial Fibrillation.

Tokai J Exp Clin Med 2016 Mar 20;41(1):4-7. Epub 2016 Mar 20.

Department of Anesthesiology, Tokai University School of Medicine, Tokyo Hospital, 1-2-5 Yoyogi, Shibuya-ku, Tokyo 151-0053, Japan.

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March 2016

S6 Kinase- and β-TrCP2-Dependent Degradation of p19Arf Is Required for Cell Proliferation.

Mol Cell Biol 2015 Oct 3;35(20):3517-27. Epub 2015 Aug 3.

Division of Cell Proliferation, ART, Graduate School of Medicine, Tohoku University, Sendai, Japan

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http://dx.doi.org/10.1128/MCB.00343-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573705PMC
October 2015

Rho-Kinase Inhibition During Early Cardiac Development Causes Arrhythmogenic Right Ventricular Cardiomyopathy in Mice.

Arterioscler Thromb Vasc Biol 2015 Oct 27;35(10):2172-84. Epub 2015 Aug 27.

From the Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan (A.E., K.S., S.S., N.K., K.S., T.M., S.I., S.T., T.S., B.E., S.M., H.S.); and Laboratory for Pharmacology, Pharmaceuticals Research Center, Asahi Kasei Pharma Corporation, Izunokuni, Japan (T.M., S.T.); Department of Clinical Physiology, Health Science, Tohoku University Graduate School of Medicine, Sendai, Japan (Y.T., T.H., M.M.); Department of Molecular Genetics, Institute of Biomedical Sciences, Fukushima Medical University School of Medicine, Fukushima, Japan (K.K., K.K.); and United Centers for Advanced Research and Translational Medicine, Core Center of Cancer Research, Division of Cell Proliferation, Tohoku University Graduate School of Medicine, Sendai, Japan (K.N.).

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http://dx.doi.org/10.1161/ATVBAHA.115.305872DOI Listing
October 2015

Isolated inclusion body myopathy caused by a multisystem proteinopathy-linked hnRNPA1 mutation.

Neurol Genet 2015 Oct 24;1(3):e23. Epub 2015 Sep 24.

Departments of Neurology (R.I., H.W., K.I., A.N., N.S., M.T., M.K., M.A.), Medical Genetics (R.I., A.N., T.N., Y.A.), the Division of Interdisciplinary Medical Science (M.S.), and the Division of Cell Proliferation (R.F., K.N.), United Centers for Advanced Research and Translational Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan; Department of Neurology (T.T.), National Hospital Organization Sendai-Nishitaga National Hospital, Sendai, Japan; Department of Neurology (M.T.), Iwate National Hospital, Ichinoseki, Japan; and Department of Neuromuscular Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry (NCNP) and Department of Genome Medicine Development, Medical Genome Center, NCNP (S.M., I.N.), Tokyo, Japan.

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http://dx.doi.org/10.1212/NXG.0000000000000023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809462PMC
October 2015

Role of the Atg9a gene in intrauterine growth and survival of fetal mice.

Reprod Biol 2015 Sep 11;15(3):131-8. Epub 2015 Jun 11.

Department of Obstetrics, Hokkaido University Graduate School of Medicine, Sapporo 060-8638, Japan.

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http://dx.doi.org/10.1016/j.repbio.2015.05.001DOI Listing
September 2015

Protein monoubiquitylation: targets and diverse functions.

Genes Cells 2015 Jul 18;20(7):543-62. Epub 2015 Jun 18.

Division of Cell Proliferation, ART, Graduate School of Medicine, Tohoku University, Sendai, 980-8575, Miyagi, Japan.

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http://dx.doi.org/10.1111/gtc.12250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744734PMC
July 2015

Mutations in PIGL in a patient with Mabry syndrome.

Am J Med Genet A 2015 Apr 23;167A(4):777-85. Epub 2015 Feb 23.

Department of Pediatrics, Tohoku University School of Medicine, Sendai, Japan.

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http://dx.doi.org/10.1002/ajmg.a.36987DOI Listing
April 2015

CRL4(VprBP) E3 ligase promotes monoubiquitylation and chromatin binding of TET dioxygenases.

Mol Cell 2015 Jan 31;57(2):247-260. Epub 2014 Dec 31.

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1016/j.molcel.2014.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304937PMC
January 2015

Analysis of the effect of canagliflozin on renal glucose reabsorption and progression of hyperglycemia in zucker diabetic Fatty rats.

J Pharmacol Exp Ther 2014 Nov 12;351(2):423-31. Epub 2014 Sep 12.

Research Division, Mitsubishi Tanabe Pharma Corporation, Toda-shi, Saitama, Japan (C.K., H.K., T.K., K.N., Y.W., N.T., K.H., Y.M., K.A., A.S., K.U., M.S.); and Janssen Research & Development LLC, Spring House, Pennsylvania (J.Z.X., S.P.L., J.Q.)

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http://jpet.aspetjournals.org/content/351/2/423.full.pdf
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http://jpet.aspetjournals.org/cgi/doi/10.1124/jpet.114.21799
Publisher Site
http://dx.doi.org/10.1124/jpet.114.217992DOI Listing
November 2014

Intraperitoneal residual contrast agent from hysterosalpingography detected following cesarean section.

Tokai J Exp Clin Med 2014 Jul 20;39(2):69-71. Epub 2014 Jul 20.

Hadano Sekijyuuji Hospital, 1-1 Tatenodai, Hadano, Kanagawa 257-0017, Japan.

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July 2014

Skp2 suppresses apoptosis in Rb1-deficient tumours by limiting E2F1 activity.

Nat Commun 2014 Mar 17;5:3463. Epub 2014 Mar 17.

Department of Developmental and Molecular Biology and Ophthalmology and Visual Sciences and Medicine, The Albert Einstein Comprehensive Cancer Center and Liver Research Center, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1038/ncomms4463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982150PMC
March 2014

RNA sequencing-based identification of aberrant imprinting in cloned mice.

Hum Mol Genet 2014 Feb 8;23(4):992-1001. Epub 2013 Oct 8.

Department of Informative Genetics, Environment and Genome Research Center.

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http://dx.doi.org/10.1093/hmg/ddt495DOI Listing
February 2014

p27 is regulated independently of Skp2 in the absence of Cdk2.

Biochim Biophys Acta 2014 Feb 21;1843(2):436-45. Epub 2013 Nov 21.

Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), 61 Biopolis Drive, Proteos#3-09, Singapore 138673, Republic of Singapore; National University of Singapore (NUS), Department of Biochemistry, Singapore 117597, Republic of Singapore; Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute-Frederick, Bldg. 560, 1050 Boyles Street, Frederick, MD 21702-1201, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2013.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915056PMC
February 2014

Novel Indole-N-glucoside, TA-1887 As a Sodium Glucose Cotransporter 2 Inhibitor for Treatment of Type 2 Diabetes.

ACS Med Chem Lett 2014 Jan 13;5(1):51-5. Epub 2013 Nov 13.

Medicinal Chemistry Research Laboratories, Pharmacology Research Laboratories, and DMPK Research Laboratories, Mitsubishi Tanabe Pharma Corporation , 2-2-50 Kawagishi, Toda, Saitama 335-8505, Japan.

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http://dx.doi.org/10.1021/ml400339bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027614PMC
January 2014

Skp2 deletion unmasks a p27 safeguard that blocks tumorigenesis in the absence of pRb and p53 tumor suppressors.

Cancer Cell 2013 Nov;24(5):645-59

Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Albert Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Marion Bessin Liver Research Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1016/j.ccr.2013.09.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880806PMC
November 2013

C-Glucosides with heteroaryl thiophene as novel sodium-dependent glucose cotransporter 2 inhibitors.

Bioorg Med Chem 2013 Sep 4;21(17):5561-72. Epub 2013 Jun 4.

Medicinal Chemistry Research Laboratories, Mitsubishi Tanabe Pharma Corporation, 2-2-50 Kawagishi, Toda, Saitama 335-8505, Japan.

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http://dx.doi.org/10.1016/j.bmc.2013.05.048DOI Listing
September 2013

Ras-induced changes in H3K27me3 occur after those in transcriptional activity.

PLoS Genet 2013 Aug 29;9(8):e1003698. Epub 2013 Aug 29.

Department of Cell Proliferation, United Center for Advanced Research and Translational Medicine, Graduate School of Medicine, Tohoku University, Seiryo-machi, Aoba-ku, Sendai, Japan.

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http://dx.doi.org/10.1371/journal.pgen.1003698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757056PMC
August 2013

Y chromosome-linked B and NK cell deficiency in mice.

J Immunol 2013 Jun 20;190(12):6209-20. Epub 2013 May 20.

Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.

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http://dx.doi.org/10.4049/jimmunol.1300303DOI Listing
June 2013

Nrf2-MafG heterodimers contribute globally to antioxidant and metabolic networks.

Nucleic Acids Res 2012 Nov 10;40(20):10228-39. Epub 2012 Sep 10.

Department of Medical Biochemistry, Tohoku Medical Megabank Organization, Sendai, 980-8575, Japan.

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http://dx.doi.org/10.1093/nar/gks827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488259PMC
November 2012

Development of mice without Cip/Kip CDK inhibitors.

Biochem Biophys Res Commun 2012 Oct 18;427(2):285-92. Epub 2012 Sep 18.

Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Fukuoka, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2012.09.041DOI Listing
October 2012

Re-investigation and RNA sequencing-based identification of genes with placenta-specific imprinted expression.

Hum Mol Genet 2012 Feb 24;21(3):548-58. Epub 2011 Oct 24.

Department of Informative Genetics, Environment and Genome Research Center, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.

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http://dx.doi.org/10.1093/hmg/ddr488DOI Listing
February 2012

Early-onset hemophagocytic lymphohistiocytosis after the start of chemotherapy for advanced neuroblastoma.

Pediatr Hematol Oncol 2012 Feb;29(1):99-103

Department of Pediatrics, Wakayama Medical University, Kimiidera Wakayama City, Japan.

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http://dx.doi.org/10.3109/08880018.2011.643529DOI Listing
February 2012

Deficient p27 phosphorylation at serine 10 increases macrophage foam cell formation and aggravates atherosclerosis through a proliferation-independent mechanism.

Arterioscler Thromb Vasc Biol 2011 Nov;31(11):2455-63

Laboratory of Molecular and Genetic Cardiovascular Pathophysiology, Department of Epidemiology, Atherothrombosis and Imaging, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain.

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http://dx.doi.org/10.1161/ATVBAHA.111.235580DOI Listing
November 2011

Deregulation of the p57-E2F1-p53 axis results in nonobstructive hydrocephalus and cerebellar malformation in mice.

Mol Cell Biol 2011 Oct 15;31(20):4176-92. Epub 2011 Aug 15.

Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Fukuoka, Fukuoka 812-8582, Japan.

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http://mcb.asm.org/cgi/doi/10.1128/MCB.05370-11
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http://dx.doi.org/10.1128/MCB.05370-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187288PMC
October 2011

p57(Kip2) and p27(Kip1) cooperate to maintain hematopoietic stem cell quiescence through interactions with Hsc70.

Cell Stem Cell 2011 Sep;9(3):247-61

Department of Cell Differentiation, The Sakaguchi Laboratory of Developmental Biology, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan.

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http://dx.doi.org/10.1016/j.stem.2011.07.003DOI Listing
September 2011

p57 is required for quiescence and maintenance of adult hematopoietic stem cells.

Cell Stem Cell 2011 Sep;9(3):262-71

Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, Fukuoka 812-8582, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S19345909110032
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http://dx.doi.org/10.1016/j.stem.2011.06.014DOI Listing
September 2011