Publications by authors named "Keaton Schmidt"

2 Publications

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Influence of maternal, anesthetic, and surgical factors on neonatal survival after emergency cesarean section in 78 dogs: A retrospective study (2002 to 2020).

Can Vet J 2021 09;62(9):961-968

Department of Small Animal Clinical Sciences, Western College of Veterinary Medicine (Schmidt, Duke-Novakovski), Department of Mathematics and Statistics (Wu), University of Saskatchewan, Campus Drive, Saskatoon, Saskatchewan, Canada S7N 5B4; Department of Community Health and Epidemiology, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia (Feng).

Neonatal mortality rate (NMR) may be affected by maternal physical condition, anesthesia, and uterine incision or neonate removal. The association of selected factors with number of dogs with dead puppies at hospital discharge was evaluated using 78 records. Data obtained at admittance for emergency cesarean section included: age, small or large body size, rectal temperature, packed cell volume, serum total protein, blood urea nitrogen, glucose, puppy in pelvic canal, and heart rate. Administration of opioids, propofol, alfaxalone, isoflurane, and sevoflurane, and anesthesia/surgical times and surgical technique were evaluated using Fisher's exact tests. There were 238 live puppies and 38 dogs had 58 dead puppies; the NMR was 19.6%. Mortality was associated with puppy in the pelvic canal ( = 0.003) and duration of anesthesia > 80 minutes ( = 0.029). Age > 8 years ( = 0.054) and induction time to start of surgery > 30 minutes ( = 0.17) may be associated with mortality. Expedient cesarean section with obstructive dystocia and an induction time to start of surgery < 30 minutes are important for puppy survival.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360313PMC
September 2021

TRANSMISSION DYNAMICS OF IN ARCTIC FOXES (): A LONG-TERM MARK-RECAPTURE SEROLOGIC STUDY AT KARRAK LAKE, NUNAVUT, CANADA.

J Wildl Dis 2019 07 28;55(3):619-626. Epub 2018 Nov 28.

1 Department of Veterinary Microbiology, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4, Canada.

Transmission dynamics of , a parasite of importance for wildlife and human health, are enigmatic in the Arctic tundra, where free-ranging wild and domestic felid definitive hosts are absent and rarely observed, respectively. Through a multiyear mark-recapture study (2011-17), serosurveillance was conducted to investigate transmission of in Arctic foxes () in the Karrak Lake region, Nunavut, Canada. Sera from adult foxes and fox pups were tested for antibodies to by using serologic methods, including the indirect fluorescent antibody test, direct agglutination test, and modified agglutination test. The overall seroprevalence was 39% in adults and 17% in pups. Mature foxes were more likely to be exposed (seroconvert) than young foxes (less than 1 yr old), with the highest level of seroprevalence in midaged foxes (2-4 yr old). Pups in two different litters were seropositive on emergence from the den, around 5 wk old, which could have been due to passive transfer of maternal antibody or vertical transmission of from mother to offspring. The seropositive pups were born of seropositive mothers that were also seropositive the year before they gave birth, suggesting that vertical transmission might not be limited to litters from mothers exposed to for the first time in pregnancy. All recaptured seropositive foxes remained seropositive on subsequent captures, suggesting that antibodies persist or foxes are constantly reexposed or a combination of both. The results of this study provided insights into how foxes were likely exposed to , the dynamics of antibody persistence and immune response, and how the parasite was maintained in a terrestrial Arctic ecosystem in the absence of felid definitive hosts.
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http://dx.doi.org/10.7589/2018-06-144DOI Listing
July 2019
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