Publications by authors named "Ke Hao"

100Publications

C21 Fraction Refined from Induced Apoptosis is Enhanced by Suppression of Autophagy in Human Gastric Cell Lines.

ACS Omega 2020 Oct 24;5(39):25156-25163. Epub 2020 Sep 24.

School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou 325035, China.

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http://dx.doi.org/10.1021/acsomega.0c02748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542599PMC
October 2020

Placental microRNA expression associates with birthweight through control of adipokines: results from two independent cohorts.

Epigenetics 2020 Oct 4:1-13. Epub 2020 Oct 4.

Gangarosa Department of Environmental Health, Rollins School of Public Health, Emory University , Atlanta, GA, USA.

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http://dx.doi.org/10.1080/15592294.2020.1827704DOI Listing
October 2020

Single-cell profiling of long noncoding RNAs and their cell lineage commitment roles via RNA-DNA-DNA triplex formation in mammary epithelium.

Stem Cells 2020 Sep 15. Epub 2020 Sep 15.

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, People's Republic of China.

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http://dx.doi.org/10.1002/stem.3274DOI Listing
September 2020

Multiple independent mechanisms link gene polymorphisms in the region of ZEB2 with risk of coronary artery disease.

Atherosclerosis 2020 Oct 29;311:20-29. Epub 2020 Aug 29.

The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA; Victor Chang Cardiac Research Institute, Darlinghurst, Australia; St Vincent's Clinical School, University of NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2020.08.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572841PMC
October 2020

Characterization of novel antigenic vaccine candidates for nile tilapia (Oreochromis niloticus) against Streptococcus agalactiae infection.

Fish Shellfish Immunol 2020 Oct 24;105:405-414. Epub 2020 Jul 24.

Institute of Animal Health, Guangdong Academy of Agricultural Sciences; Key Laboratory of Livestock Disease Prevention of Guangdong Province; Scientific Observation and Experiment Station of Veterinary Drugs and Diagnostic Techniques of Guangdong Province, Ministry of Agriculture and Rural Affairs, PRC, Guangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.fsi.2020.07.024DOI Listing
October 2020

Identification and Bioinformatic Analysis of Circular RNA Expression in Peripheral Blood Mononuclear Cells from Patients with Chronic Obstructive Pulmonary Disease.

Int J Chron Obstruct Pulmon Dis 2020 16;15:1391-1401. Epub 2020 Jun 16.

Peking University China-Japan Friendship School of Clinical Medicine, Beijing, People's Republic of China.

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http://dx.doi.org/10.2147/COPD.S252896DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305829PMC
June 2020

Seasonally variant gene expression in full-term human placenta.

FASEB J 2020 Jun 23. Epub 2020 Jun 23.

Gangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA.

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http://dx.doi.org/10.1096/fj.202000291RDOI Listing
June 2020

Prenatal exposure to ambient air multi-pollutants significantly impairs intrauterine fetal development trajectory.

Ecotoxicol Environ Saf 2020 Sep 29;201:110726. Epub 2020 May 29.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Respiratory Medicine, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China; College of Environmental Science and Engineering, Tongji University, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.ecoenv.2020.110726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363555PMC
September 2020

Placental lncRNA expression associated with placental cadmium concentrations and birth weight.

Environ Epigenet 2020 Jan 10;6(1):dvaa003. Epub 2020 May 10.

Department of Environmental Health, Rollins School of Public Health at Emory University, Atlanta, GA, USA.

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http://dx.doi.org/10.1093/eep/dvaa003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211362PMC
January 2020

Caveolin-1 Promotes Chemoresistance of Gastric Cancer Cells to Cisplatin by Activating WNT/β-Catenin Pathway.

Front Oncol 2020 3;10:46. Epub 2020 Feb 3.

Guangdong Provincial Key Laboratory of Regional Immunity and Diseases, Department of Pharmacology and Shenzhen University International Cancer Center, Shenzhen University School of Medicine, Shenzhen, China.

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http://dx.doi.org/10.3389/fonc.2020.00046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008851PMC
February 2020

Selenium-associated DNA methylation modifications in placenta and neurobehavioral development of newborns: An epigenome-wide study of two U.S. birth cohorts.

Environ Int 2020 04 31;137:105508. Epub 2020 Jan 31.

Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA; Children's Environmental Health and Disease Prevention Research Center at Dartmouth, Dartmouth College, Lebanon, NH, USA. Electronic address:

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http://dx.doi.org/10.1016/j.envint.2020.105508DOI Listing
April 2020

TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh.

Nat Commun 2020 01 17;11(1):341. Epub 2020 Jan 17.

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, 650223, Kunming, China.

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http://dx.doi.org/10.1038/s41467-019-14183-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969145PMC
January 2020

Association of adverse birth outcomes with prenatal uranium exposure: A population-based cohort study.

Environ Int 2020 02 23;135:105391. Epub 2019 Dec 23.

Key Laboratory of Environment and Health (HUST), Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. Electronic address:

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http://dx.doi.org/10.1016/j.envint.2019.105391DOI Listing
February 2020

The pharmacogenomics of inhaled corticosteroids and lung function decline in COPD.

Eur Respir J 2019 12 4;54(6). Epub 2019 Dec 4.

The University of British Columbia Center for Heart Lung Innovation, St Paul's Hospital Vancouver, BC, Canada.

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http://dx.doi.org/10.1183/13993003.00521-2019DOI Listing
December 2019

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration.

Nat Commun 2019 09 2;10(1):3927. Epub 2019 Sep 2.

Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/s41467-019-11881-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718389PMC
September 2019

Copper associates with differential methylation in placentae from two US birth cohorts.

Epigenetics 2020 03 4;15(3):215-230. Epub 2019 Sep 4.

Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA.

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http://dx.doi.org/10.1080/15592294.2019.1661211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028322PMC
March 2020

Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

Authors:
Nick Shrine Anna L Guyatt A Mesut Erzurumluoglu Victoria E Jackson Brian D Hobbs Carl A Melbourne Chiara Batini Katherine A Fawcett Kijoung Song Phuwanat Sakornsakolpat Xingnan Li Ruth Boxall Nicola F Reeve Ma'en Obeidat Jing Hua Zhao Matthias Wielscher Stefan Weiss Katherine A Kentistou James P Cook Benjamin B Sun Jian Zhou Jennie Hui Stefan Karrasch Medea Imboden Sarah E Harris Jonathan Marten Stefan Enroth Shona M Kerr Ida Surakka Veronique Vitart Terho Lehtimäki Richard J Allen Per S Bakke Terri H Beaty Eugene R Bleecker Yohan Bossé Corry-Anke Brandsma Zhengming Chen James D Crapo John Danesh Dawn L DeMeo Frank Dudbridge Ralf Ewert Christian Gieger Amund Gulsvik Anna L Hansell Ke Hao Joshua D Hoffman John E Hokanson Georg Homuth Peter K Joshi Philippe Joubert Claudia Langenberg Xuan Li Liming Li Kuang Lin Lars Lind Nicholas Locantore Jian'an Luan Anubha Mahajan Joseph C Maranville Alison Murray David C Nickle Richard Packer Margaret M Parker Megan L Paynton David J Porteous Dmitry Prokopenko Dandi Qiao Rajesh Rawal Heiko Runz Ian Sayers Don D Sin Blair H Smith María Soler Artigas David Sparrow Ruth Tal-Singer Paul R H J Timmers Maarten Van den Berge John C Whittaker Prescott G Woodruff Laura M Yerges-Armstrong Olga G Troyanskaya Olli T Raitakari Mika Kähönen Ozren Polašek Ulf Gyllensten Igor Rudan Ian J Deary Nicole M Probst-Hensch Holger Schulz Alan L James James F Wilson Beate Stubbe Eleftheria Zeggini Marjo-Riitta Jarvelin Nick Wareham Edwin K Silverman Caroline Hayward Andrew P Morris Adam S Butterworth Robert A Scott Robin G Walters Deborah A Meyers Michael H Cho David P Strachan Ian P Hall Martin D Tobin Louise V Wain

Nat Genet 2019 Jun;51(6):1067

Department of Health Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1038/s41588-019-0438-3DOI Listing
June 2019

TDP-43 is Required for Mammary Gland Repopulation and Proliferation of Mammary Epithelial Cells.

Stem Cells Dev 2019 07 11;28(14):944-953. Epub 2019 Jun 11.

2State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.

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http://dx.doi.org/10.1089/scd.2019.0011DOI Listing
July 2019

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.

Authors:
Nicole M Warrington Robin N Beaumont Momoko Horikoshi Felix R Day Øyvind Helgeland Charles Laurin Jonas Bacelis Shouneng Peng Ke Hao Bjarke Feenstra Andrew R Wood Anubha Mahajan Jessica Tyrrell Neil R Robertson N William Rayner Zhen Qiao Gunn-Helen Moen Marc Vaudel Carmen J Marsit Jia Chen Michael Nodzenski Theresia M Schnurr Mohammad H Zafarmand Jonathan P Bradfield Niels Grarup Marjolein N Kooijman Ruifang Li-Gao Frank Geller Tarunveer S Ahluwalia Lavinia Paternoster Rico Rueedi Ville Huikari Jouke-Jan Hottenga Leo-Pekka Lyytikäinen Alana Cavadino Sarah Metrustry Diana L Cousminer Ying Wu Elisabeth Thiering Carol A Wang Christian T Have Natalia Vilor-Tejedor Peter K Joshi Jodie N Painter Ioanna Ntalla Ronny Myhre Niina Pitkänen Elisabeth M van Leeuwen Raimo Joro Vasiliki Lagou Rebecca C Richmond Ana Espinosa Sheila J Barton Hazel M Inskip John W Holloway Loreto Santa-Marina Xavier Estivill Wei Ang Julie A Marsh Christoph Reichetzeder Letizia Marullo Berthold Hocher Kathryn L Lunetta Joanne M Murabito Caroline L Relton Manolis Kogevinas Leda Chatzi Catherine Allard Luigi Bouchard Marie-France Hivert Ge Zhang Louis J Muglia Jani Heikkinen Camilla S Morgen Antoine H C van Kampen Barbera D C van Schaik Frank D Mentch Claudia Langenberg Jian'an Luan Robert A Scott Jing Hua Zhao Gibran Hemani Susan M Ring Amanda J Bennett Kyle J Gaulton Juan Fernandez-Tajes Natalie R van Zuydam Carolina Medina-Gomez Hugoline G de Haan Frits R Rosendaal Zoltán Kutalik Pedro Marques-Vidal Shikta Das Gonneke Willemsen Hamdi Mbarek Martina Müller-Nurasyid Marie Standl Emil V R Appel Cilius E Fonvig Caecilie Trier Catharina E M van Beijsterveldt Mario Murcia Mariona Bustamante Sílvia Bonas-Guarch David M Hougaard Josep M Mercader Allan Linneberg Katharina E Schraut Penelope A Lind Sarah E Medland Beverley M Shields Bridget A Knight Jin-Fang Chai Kalliope Panoutsopoulou Meike Bartels Friman Sánchez Jakob Stokholm David Torrents Rebecca K Vinding Sara M Willems Mustafa Atalay Bo L Chawes Peter Kovacs Inga Prokopenko Marcus A Tuke Hanieh Yaghootkar Katherine S Ruth Samuel E Jones Po-Ru Loh Anna Murray Michael N Weedon Anke Tönjes Michael Stumvoll Kim F Michaelsen Aino-Maija Eloranta Timo A Lakka Cornelia M van Duijn Wieland Kiess Antje Körner Harri Niinikoski Katja Pahkala Olli T Raitakari Bo Jacobsson Eleftheria Zeggini George V Dedoussis Yik-Ying Teo Seang-Mei Saw Grant W Montgomery Harry Campbell James F Wilson Tanja G M Vrijkotte Martine Vrijheid Eco J C N de Geus M Geoffrey Hayes Haja N Kadarmideen Jens-Christian Holm Lawrence J Beilin Craig E Pennell Joachim Heinrich Linda S Adair Judith B Borja Karen L Mohlke Johan G Eriksson Elisabeth E Widén Andrew T Hattersley Tim D Spector Mika Kähönen Jorma S Viikari Terho Lehtimäki Dorret I Boomsma Sylvain Sebert Peter Vollenweider Thorkild I A Sørensen Hans Bisgaard Klaus Bønnelykke Jeffrey C Murray Mads Melbye Ellen A Nohr Dennis O Mook-Kanamori Fernando Rivadeneira Albert Hofman Janine F Felix Vincent W V Jaddoe Torben Hansen Charlotta Pisinger Allan A Vaag Oluf Pedersen André G Uitterlinden Marjo-Riitta Järvelin Christine Power Elina Hyppönen Denise M Scholtens William L Lowe George Davey Smith Nicholas J Timpson Andrew P Morris Nicholas J Wareham Hakon Hakonarson Struan F A Grant Timothy M Frayling Debbie A Lawlor Pål R Njølstad Stefan Johansson Ken K Ong Mark I McCarthy John R B Perry David M Evans Rachel M Freathy

Nat Genet 2019 05 1;51(5):804-814. Epub 2019 May 1.

Institute of Biomedical and Clinical Science, College of Medicine and Health, University of Exeter, Royal Devon and Exeter Hospital, Exeter, UK.

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http://dx.doi.org/10.1038/s41588-019-0403-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522365PMC
May 2019

Maternal circadian disruption is associated with variation in placental DNA methylation.

PLoS One 2019 26;14(4):e0215745. Epub 2019 Apr 26.

Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215745PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485638PMC
February 2020

Prenatal exposure to benzophenones, parabens and triclosan and neurocognitive development at 2 years.

Environ Int 2019 05 2;126:413-421. Epub 2019 Mar 2.

Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.envint.2019.01.023DOI Listing
May 2019

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

Authors:
Nick Shrine Anna L Guyatt A Mesut Erzurumluoglu Victoria E Jackson Brian D Hobbs Carl A Melbourne Chiara Batini Katherine A Fawcett Kijoung Song Phuwanat Sakornsakolpat Xingnan Li Ruth Boxall Nicola F Reeve Ma'en Obeidat Jing Hua Zhao Matthias Wielscher Stefan Weiss Katherine A Kentistou James P Cook Benjamin B Sun Jian Zhou Jennie Hui Stefan Karrasch Medea Imboden Sarah E Harris Jonathan Marten Stefan Enroth Shona M Kerr Ida Surakka Veronique Vitart Terho Lehtimäki Richard J Allen Per S Bakke Terri H Beaty Eugene R Bleecker Yohan Bossé Corry-Anke Brandsma Zhengming Chen James D Crapo John Danesh Dawn L DeMeo Frank Dudbridge Ralf Ewert Christian Gieger Amund Gulsvik Anna L Hansell Ke Hao Joshua D Hoffman John E Hokanson Georg Homuth Peter K Joshi Philippe Joubert Claudia Langenberg Xuan Li Liming Li Kuang Lin Lars Lind Nicholas Locantore Jian'an Luan Anubha Mahajan Joseph C Maranville Alison Murray David C Nickle Richard Packer Margaret M Parker Megan L Paynton David J Porteous Dmitry Prokopenko Dandi Qiao Rajesh Rawal Heiko Runz Ian Sayers Don D Sin Blair H Smith María Soler Artigas David Sparrow Ruth Tal-Singer Paul R H J Timmers Maarten Van den Berge John C Whittaker Prescott G Woodruff Laura M Yerges-Armstrong Olga G Troyanskaya Olli T Raitakari Mika Kähönen Ozren Polašek Ulf Gyllensten Igor Rudan Ian J Deary Nicole M Probst-Hensch Holger Schulz Alan L James James F Wilson Beate Stubbe Eleftheria Zeggini Marjo-Riitta Jarvelin Nick Wareham Edwin K Silverman Caroline Hayward Andrew P Morris Adam S Butterworth Robert A Scott Robin G Walters Deborah A Meyers Michael H Cho David P Strachan Ian P Hall Martin D Tobin Louise V Wain

Nat Genet 2019 03 25;51(3):481-493. Epub 2019 Feb 25.

Department of Health Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1038/s41588-018-0321-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397078PMC
March 2019

Gut microbiota density influences host physiology and is shaped by host and microbial factors.

Elife 2019 01 22;8. Epub 2019 Jan 22.

Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, United States.

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https://elifesciences.org/articles/40553
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http://dx.doi.org/10.7554/eLife.40553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342524PMC
January 2019

Heterogeneity in gut microbiota drive polyphenol metabolism that influences α-synuclein misfolding and toxicity.

J Nutr Biochem 2019 02 14;64:170-181. Epub 2018 Nov 14.

Department of Neurology, Icahn School of Medicine at Mount Sinai, NY, New York, USA 10029; Geriatric Research, Education and Clinical Center, James J. Peters Veterans Affairs Medical Center, Bronx, New York, USA 10468. Electronic address:

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http://dx.doi.org/10.1016/j.jnutbio.2018.10.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363841PMC
February 2019

Placental MAOA expression mediates prenatal stress effects on temperament in 12-month-olds.

Infant Child Dev 2018 Jul-Aug;27(4). Epub 2018 Apr 16.

Clinical Psychology Program, The Graduate Center (CUNY), New York, New York, USA.

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http://dx.doi.org/10.1002/icd.2094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261505PMC
April 2018

BioAir, an integrative system for monitoring individual-level air pollutant exposure with high time and spatial resolution.

Ecotoxicol Environ Saf 2019 Mar 28;169:756-763. Epub 2018 Nov 28.

Department of Respiratory Medicine, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China; College of Environmental Science and Engineering, Tongji University, Shanghai, China; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Ninghai First Hospital, Ningbo, Zhejiang, China. Electronic address:

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http://dx.doi.org/10.1016/j.ecoenv.2018.11.067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311139PMC
March 2019

[Development and verification of reference nucleic acid materials of H9N2 influenza viruses by real-time RT-PCR].

Sheng Wu Gong Cheng Xue Bao 2018 Oct;34(10):1579-1586

Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.

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http://journals.im.ac.cn/cjbcn/ch/reader/view_abstract.aspx?
Publisher Site
http://dx.doi.org/10.13345/j.cjb.180034DOI Listing
October 2018

Airway microbiome is associated with respiratory functions and responses to ambient particulate matter exposure.

Ecotoxicol Environ Saf 2019 Jan 18;167:269-277. Epub 2018 Oct 18.

Department of Respiratory Medicine, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China; College of Environmental Science and Engineering, Tongji University, Shanghai, China; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ecoenv.2018.09.079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257984PMC
January 2019

A novel absorption spectrometric method, based on graphene nanomaterials, for detection of hepatocellular carcinoma-specific T lymphocyte cells.

Int J Nanomedicine 2018 19;13:5523-5536. Epub 2018 Sep 19.

Department of Clinical Laboratory, Chun'an First People's Hospital (Zhejiang Provincial People's Hospital Chun'an Branch), Hangzhou, Zhejiang Province, China,

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http://dx.doi.org/10.2147/IJN.S168574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154735PMC
November 2018

Meta-analysis of exome array data identifies six novel genetic loci for lung function.

Authors:
Victoria E Jackson Jeanne C Latourelle Louise V Wain Albert V Smith Megan L Grove Traci M Bartz Ma'en Obeidat Michael A Province Wei Gao Beenish Qaiser David J Porteous Patricia A Cassano Tarunveer S Ahluwalia Niels Grarup Jin Li Elisabeth Altmaier Jonathan Marten Sarah E Harris Ani Manichaikul Tess D Pottinger Ruifang Li-Gao Allan Lind-Thomsen Anubha Mahajan Lies Lahousse Medea Imboden Alexander Teumer Bram Prins Leo-Pekka Lyytikäinen Gudny Eiriksdottir Nora Franceschini Colleen M Sitlani Jennifer A Brody Yohan Bossé Wim Timens Aldi Kraja Anu Loukola Wenbo Tang Yongmei Liu Jette Bork-Jensen Johanne M Justesen Allan Linneberg Leslie A Lange Rajesh Rawal Stefan Karrasch Jennifer E Huffman Blair H Smith Gail Davies Kristin M Burkart Josyf C Mychaleckyj Tobias N Bonten Stefan Enroth Lars Lind Guy G Brusselle Ashish Kumar Beate Stubbe Mika Kähönen Annah B Wyss Bruce M Psaty Susan R Heckbert Ke Hao Taina Rantanen Stephen B Kritchevsky Kurt Lohman Tea Skaaby Charlotta Pisinger Torben Hansen Holger Schulz Ozren Polasek Archie Campbell John M Starr Stephen S Rich Dennis O Mook-Kanamori Åsa Johansson Erik Ingelsson André G Uitterlinden Stefan Weiss Olli T Raitakari Vilmundur Gudnason Kari E North Sina A Gharib Don D Sin Kent D Taylor George T O'Connor Jaakko Kaprio Tamara B Harris Oluf Pederson Henrik Vestergaard James G Wilson Konstantin Strauch Caroline Hayward Shona Kerr Ian J Deary R Graham Barr Renée de Mutsert Ulf Gyllensten Andrew P Morris M Arfan Ikram Nicole Probst-Hensch Sven Gläser Eleftheria Zeggini Terho Lehtimäki David P Strachan Josée Dupuis Alanna C Morrison Ian P Hall Martin D Tobin Stephanie J London

Wellcome Open Res 2018 12;3. Epub 2018 Jan 12.

Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Dept of Health and Human Services, Research Triangle Park, NC, 27709, USA.

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http://dx.doi.org/10.12688/wellcomeopenres.12583.3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081985PMC
January 2018

Intrauterine multi-metal exposure is associated with reduced fetal growth through modulation of the placental gene network.

Environ Int 2018 11 17;120:373-381. Epub 2018 Aug 17.

Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.envint.2018.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288802PMC
November 2018

[Exploration and characterization of a universal piggyBac transposon vector for efficient transgene studies in sheep].

Yi Chuan 2018 Aug;40(8):647-656

College of Animal Science and Technology, Shihezi University, Shihezi 832000, China.

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http://dx.doi.org/10.16288/j.yczz.17-421DOI Listing
August 2018

LncRNA MIR100HG promotes cell proliferation in triple-negative breast cancer through triplex formation with p27 loci.

Cell Death Dis 2018 07 24;9(8):805. Epub 2018 Jul 24.

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, 650223, China.

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http://dx.doi.org/10.1038/s41419-018-0869-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057987PMC
July 2018

Using SAAS-CNV to Detect and Characterize Somatic Copy Number Alterations in Cancer Genomes from Next Generation Sequencing and SNP Array Data.

Methods Mol Biol 2018 ;1833:29-47

Department of Genetics and Genomic Sciences, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1007/978-1-4939-8666-8_2DOI Listing
March 2019

GIGSEA: genotype imputed gene set enrichment analysis using GWAS summary level data.

Bioinformatics 2019 01;35(1):160-163

Department of Genetics and Genomic Sciences and Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1093/bioinformatics/bty529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298047PMC
January 2019

miR-140-5p suppresses retinoblastoma cell proliferation, migration, and invasion by targeting CEMIP and CADM3.

Cell Mol Biol (Noisy-le-grand) 2018 May 15;64(6):42-47. Epub 2018 May 15.

Research Center of Blood Transfusion Medicine, Education Ministry Key Laboratory of Laboratory Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou medical College, China.

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May 2018

Loss of TDP43 inhibits progression of triple-negative breast cancer in coordination with SRSF3.

Proc Natl Acad Sci U S A 2018 04 26;115(15):E3426-E3435. Epub 2018 Mar 26.

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, 650223 Kunming, China;

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http://dx.doi.org/10.1073/pnas.1714573115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899436PMC
April 2018

Genome-wide association study of maternal genetic effects and parent-of-origin effects on food allergy.

Medicine (Baltimore) 2018 Mar;97(9):e0043

Department of Population, Family and Reproductive Health, Center on the Early Life Origins of Disease, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD.

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http://dx.doi.org/10.1097/MD.0000000000010043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851764PMC
March 2018

Cadmium-Associated Differential Methylation throughout the Placental Genome: Epigenome-Wide Association Study of Two U.S. Birth Cohorts.

Environ Health Perspect 2018 01 22;126(1):017010. Epub 2018 Jan 22.

Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA

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http://dx.doi.org/10.1289/EHP2192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014712PMC
January 2018

C21 steroid-enriched fraction refined from inhibits hepatocellular carcinoma through the coordination of Hippo-Yap and PTEN-PI3K/AKT signaling pathways.

Oncotarget 2017 Dec 30;8(66):110576-110591. Epub 2017 Nov 30.

Research Center of Blood Transfusion Medicine, Education Ministry Key Laboratory of Laboratory Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China.

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http://dx.doi.org/10.18632/oncotarget.22833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746405PMC
December 2017

Genetic Pleiotropy between Nicotine Dependence and Respiratory Outcomes.

Sci Rep 2017 12 4;7(1):16907. Epub 2017 Dec 4.

Department of Respiratory Medicine, Shanghai Tenth People's Hospital, Tongji University, Shanghai 200072, China.

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http://dx.doi.org/10.1038/s41598-017-16964-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715160PMC
December 2017

Learning the deformation mechanism of poly(vinylidine fluoride-co-chlorotrifluoroethylene): an insight into strain-induced microstructure evolution via molecular dynamics.

J Mol Model 2017 Nov 29;23(12):361. Epub 2017 Nov 29.

Institute of Chemical Materials, China Academy of Engineering Physics (CAEP), P.O. Box 919-311, Mianyang, Sichuan, 621900, China.

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http://dx.doi.org/10.1007/s00894-017-3529-zDOI Listing
November 2017

Investigation of the 'double cross' splitting mechanism of single-crystal diamond under nanoindentation via molecular dynamics simulation.

J Mol Model 2017 Sep 29;23(10):299. Epub 2017 Sep 29.

Institute of Chemical Materials, China Academy of Engineering Physics, P.O. Box 919-327, Mianyang, Sichuan, 621900, China.

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http://dx.doi.org/10.1007/s00894-017-3467-9DOI Listing
September 2017

extract-induced growth inhibition and apoptosis in hepatoma carcinoma cells is mediated through the p53/nuclear factor-κB signaling pathway.

Exp Ther Med 2017 Sep 25;14(3):2477-2484. Epub 2017 Jul 25.

Research Center of Blood Transfusion Medicine, Education Ministry Key Laboratory of Laboratory Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China.

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http://dx.doi.org/10.3892/etm.2017.4833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609296PMC
September 2017

LuxS/AI-2 in Streptococcus agalactiae reveals a key role in acid tolerance and virulence.

Res Vet Sci 2017 Dec 4;115:501-507. Epub 2017 Aug 4.

College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China. Electronic address:

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http://dx.doi.org/10.1016/j.rvsc.2017.07.032DOI Listing
December 2017

Trunk mutational events present minimal intra- and inter-tumoral heterogeneity in hepatocellular carcinoma.

J Hepatol 2017 12 24;67(6):1222-1231. Epub 2017 Aug 24.

Mount Sinai Liver Cancer Program (Divisions of Liver Diseases, Department of Medicine, Department of Pathology, Recanati Miller Transplantation Institute), Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, USA; Liver Cancer Translational Research Laboratory, BCLC Group, IDIBAPS, Liver Unit, Hospital Clinic, University of Barcelona, Barcelona, Catalonia, Spain; Institució Catalana de Recerca i Estudis Avançats, Barcelona, Catalonia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2017.08.013DOI Listing
December 2017

Particulate Matter Exposure and Stress Hormone Levels: A Randomized, Double-Blind, Crossover Trial of Air Purification.

Circulation 2017 Aug;136(7):618-627

From School of Public Health, Key Lab of Public Health Safety of the Ministry of Education and Key Lab of Health Technology Assessment of the Ministry of Health, Fudan University, Shanghai, China (H.L., J.C., R.C., Z.Z., Z.Y., H.K.); Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention (LAP3), Fudan University, China (J.C., R.C., Z.Y., L.W., J.C.); Department of Genetics and Genomics Sciences, Icahn School of Medicine at Mount Sinai, New York, NY (K.H.); The Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY (K.H.); Department of Respiratory Medicine, Shanghai Tenth People's Hospital, Tongji University, China (K.H.); Department of Environmental Health, School of Public Health, Boston University, MA (P.L.K.); Department of Epidemiology and Biostatistics, College of Human Medicine, Michigan State University, East Lansing (H.C.); and Key Laboratory of Reproduction Regulation of NPFPC, SIPPR, IRD, Fudan University, Shanghai, China (H.K.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.026796DOI Listing
August 2017

Role of the Lung Microbiome in the Pathogenesis of Chronic Obstructive Pulmonary Disease.

Chin Med J (Engl) 2017 Sep;130(17):2107-2111

Department of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing 100029, China.

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http://dx.doi.org/10.4103/0366-6999.211452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586181PMC
September 2017

APOL1 G2 risk allele-clarifying nomenclature.

Kidney Int 2017 08;92(2):518-519

Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA; Recanati Miller Transplant Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2017.05.009DOI Listing
August 2017

Whole-transcriptome analysis delineates the human placenta gene network and its associations with fetal growth.

BMC Genomics 2017 07 10;18(1):520. Epub 2017 Jul 10.

Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.

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http://bmcgenomics.biomedcentral.com/articles/10.1186/s12864
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http://dx.doi.org/10.1186/s12864-017-3878-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502484PMC
July 2017

Cytotoxicity of anti-tumor herbal Marsdeniae tenacissimae extract on erythrocytes.

J Zhejiang Univ Sci B 2017 Jul;18(7):597-604

Research Center of Blood Transfusion Medicine, Ministry of Education Key Laboratory of Laboratory Medicine, Department of Blood Transfusion, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China.

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http://dx.doi.org/10.1631/jzus.B1600228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498840PMC
July 2017

Maternal exposure to selenium and cadmium, fetal growth, and placental expression of steroidogenic and apoptotic genes.

Environ Res 2017 10 3;158:233-244. Epub 2017 Jul 3.

Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.envres.2017.06.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554457PMC
October 2017

Protective efficacy of cationic-PLGA microspheres loaded with DNA vaccine encoding the sip gene of Streptococcus agalactiae in tilapia.

Fish Shellfish Immunol 2017 Jul 2;66:345-353. Epub 2017 May 2.

Guangdong Provincial Key Laboratory of Livestock Disease Prevention; Guangdong Open Laboratory of Veterinary Public Health; Institute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China. Electronic address:

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http://dx.doi.org/10.1016/j.fsi.2017.05.003DOI Listing
July 2017

Responsiveness to Ipratropium Bromide in Male and Female Patients with Mild to Moderate Chronic Obstructive Pulmonary Disease.

EBioMedicine 2017 May 12;19:139-145. Epub 2017 Apr 12.

UBC Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada; Department of Medicine (Pulmonary Division), University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.04.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440622PMC
May 2017

The anti-hepatocellular carcinoma cell activity by a novel mTOR kinase inhibitor CZ415.

Biochem Biophys Res Commun 2017 06 30;487(3):494-499. Epub 2017 Mar 30.

Research Center of Blood Transfusion Medicine, Education Ministry Key Laboratory of Laboratory Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou medical College, Hangzhou, China; Clinical Research Institute, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou medical College, Hangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2017.03.156DOI Listing
June 2017

Marsdeniae tenacissimae extract (MTE) suppresses cell proliferation by attenuating VEGF/VEGFR2 interactions and promotes apoptosis through regulating PKC pathway in human umbilical vein endothelial cells.

Chin J Nat Med 2016 Dec;14(12):922-930

Research Center of Blood Transfusion Medicine, Education Ministry Key Laboratory of Laboratory Medicine, Zhejiang Provincial People's Hospital, Hangzhou, 310014, China; School of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou 325000, China. Electronic address:

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http://dx.doi.org/10.1016/S1875-5364(17)30017-1DOI Listing
December 2016

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.

Authors:
Louise V Wain Nick Shrine María Soler Artigas A Mesut Erzurumluoglu Boris Noyvert Lara Bossini-Castillo Ma'en Obeidat Amanda P Henry Michael A Portelli Robert J Hall Charlotte K Billington Tracy L Rimington Anthony G Fenech Catherine John Tineka Blake Victoria E Jackson Richard J Allen Bram P Prins Archie Campbell David J Porteous Marjo-Riitta Jarvelin Matthias Wielscher Alan L James Jennie Hui Nicholas J Wareham Jing Hua Zhao James F Wilson Peter K Joshi Beate Stubbe Rajesh Rawal Holger Schulz Medea Imboden Nicole M Probst-Hensch Stefan Karrasch Christian Gieger Ian J Deary Sarah E Harris Jonathan Marten Igor Rudan Stefan Enroth Ulf Gyllensten Shona M Kerr Ozren Polasek Mika Kähönen Ida Surakka Veronique Vitart Caroline Hayward Terho Lehtimäki Olli T Raitakari David M Evans A John Henderson Craig E Pennell Carol A Wang Peter D Sly Emily S Wan Robert Busch Brian D Hobbs Augusto A Litonjua David W Sparrow Amund Gulsvik Per S Bakke James D Crapo Terri H Beaty Nadia N Hansel Rasika A Mathias Ingo Ruczinski Kathleen C Barnes Yohan Bossé Philippe Joubert Maarten van den Berge Corry-Anke Brandsma Peter D Paré Don D Sin David C Nickle Ke Hao Omri Gottesman Frederick E Dewey Shannon E Bruse David J Carey H Lester Kirchner Stefan Jonsson Gudmar Thorleifsson Ingileif Jonsdottir Thorarinn Gislason Kari Stefansson Claudia Schurmann Girish Nadkarni Erwin P Bottinger Ruth J F Loos Robin G Walters Zhengming Chen Iona Y Millwood Julien Vaucher Om P Kurmi Liming Li Anna L Hansell Chris Brightling Eleftheria Zeggini Michael H Cho Edwin K Silverman Ian Sayers Gosia Trynka Andrew P Morris David P Strachan Ian P Hall Martin D Tobin

Nat Genet 2017 Mar 6;49(3):416-425. Epub 2017 Feb 6.

Department of Health Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1038/ng.3787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326681PMC
March 2017

Genome-wide DNA methylation associations with spontaneous preterm birth in US blacks: findings in maternal and cord blood samples.

Epigenetics 2018 6;13(2):163-172. Epub 2018 Mar 6.

a Department of Population , Family and Reproductive Health , Center on the Early Life Origins of Disease , Johns Hopkins University Bloomberg School of Public Health , Baltimore , MD , USA.

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https://www.tandfonline.com/doi/full/10.1080/15592294.2017.1
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http://dx.doi.org/10.1080/15592294.2017.1287654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873359PMC
December 2018

High-Throughput Characterization of Blood Serum Proteomics of IBD Patients with Respect to Aging and Genetic Factors.

PLoS Genet 2017 01 27;13(1):e1006565. Epub 2017 Jan 27.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271178PMC
January 2017

Mixed hepatocellular cholangiocarcinoma tumors: Cholangiolocellular carcinoma is a distinct molecular entity.

J Hepatol 2017 05 23;66(5):952-961. Epub 2017 Jan 23.

Liver Cancer Translational Research Laboratory, Liver Unit, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic, CIBERehd, Universitat de Barcelona, Barcelona, Catalonia, Spain; Mount Sinai Liver Cancer Program, (Divisions of Liver Diseases, Hematology and Medical Oncology, Department of Medicine, Department of Pathology, Recanati Miller Transplantation Institute), Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, USA; Institució Catalana de Recerca i Estudis Avançats, Barcelona, Catalonia, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01688278173001
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http://dx.doi.org/10.1016/j.jhep.2017.01.010DOI Listing
May 2017

CD103 Cell Growth Factor Flt3L Enhances the Efficacy of Immune Checkpoint Blockades in Murine Glioblastoma Model.

Oncol Res 2018 Mar 20;26(2):173-182. Epub 2017 Jan 20.

School of Laboratory Medicine and Life Science, Wenzhou Medical University, Zhejiang, P.R. China.

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http://dx.doi.org/10.3727/096504017X14841698396865DOI Listing
March 2018

The Efficacy and Risk Profile of c-Met inhibitors in Non-small Cell Lung Cancer: a Meta-analysis.

Sci Rep 2016 10 27;6:35770. Epub 2016 Oct 27.

Department of Respiratory Medicine, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, China.

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http://dx.doi.org/10.1038/srep35770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081544PMC
October 2016

Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases.

Science 2016 Aug;353(6301):827-30

Department of Genetics and Genomic Sciences, The Icahn Institute for Genomics and Multiscale Biology Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York , NY 10029, USA. Clinical Gene Networks AB, Jungfrugatan 10, 114 44 Stockholm, Sweden. Department of Pathophysiology, Institute of Biomedicine and Translation Medicine, University of Tartu, Biomeedikum, Ravila 19, 50411, Tartu, Estonia. Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Scheeles Väg 2, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1126/science.aad6970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534139PMC
August 2016

A loss of function variant in CASP7 protects against Alzheimer's disease in homozygous APOE ε4 allele carriers.

BMC Genomics 2016 06 23;17 Suppl 2:445. Epub 2016 Jun 23.

Department of Genetics and Genomic Sciences, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.

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http://dx.doi.org/10.1186/s12864-016-2725-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928152PMC
June 2016

Epigenome-wide association study links site-specific DNA methylation changes with cow's milk allergy.

J Allergy Clin Immunol 2016 09 25;138(3):908-911.e9. Epub 2016 Apr 25.

Department of Population, Family and Reproductive Health, Center on the Early Life Origins of Disease, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Md; Division of General Pediatrics & Adolescent Medicine, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Md. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.01.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392112PMC
September 2016