Publications by authors named "Kazuyuki Tobe"

100Publications

CD206+ M2-Like Macrophages Are Essential for Successful Implantation.

Front Immunol 2020 23;11:557184. Epub 2020 Oct 23.

Department of Obstetrics and Gynecology, Faculty of Medicine, University of Toyama, Toyama, Japan.

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http://dx.doi.org/10.3389/fimmu.2020.557184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644510PMC
October 2020

Anti-obesity effect of a hop-derived prenylflavonoid isoxanthohumol in a high-fat diet-induced obese mouse model.

Biosci Microbiota Food Health 2020 25;39(3):175-182. Epub 2020 Mar 25.

Research Institute, Suntory Global Innovation Center Ltd., 8-1-1 Seikadai, Seika-cho, Soraku-gun, Kyoto 619-0284, Japan.

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http://dx.doi.org/10.12938/bmfh.2019-040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392919PMC
March 2020

Isoxanthohumol, a hop-derived flavonoid, alters the metabolomics profile of mouse feces.

Biosci Microbiota Food Health 2020 21;39(3):100-108. Epub 2020 Feb 21.

Research Institute, Suntory Global Innovation Center Limited, 8-1-1 Seikadai, Seika-cho, Soraku-gun, Kyoto 619-0284, Japan.

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http://dx.doi.org/10.12938/bmfh.2019-045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392914PMC
February 2020

Insulin- and Lipopolysaccharide-Mediated Signaling in Adipose Tissue Macrophages Regulates Postprandial Glycemia through Akt-mTOR Activation.

Mol Cell 2020 07 27;79(1):43-53.e4. Epub 2020 May 27.

Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan; Department of Molecular Diabetic Medicine, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2020.04.033DOI Listing
July 2020

Linkage of CD8 T cell exhaustion with high-fat diet-induced tumourigenesis.

Sci Rep 2019 08 22;9(1):12284. Epub 2019 Aug 22.

First Department of Internal Medicine, Graduate School of Medicine and Pharmaceutical Science, University of Toyama, Toyama, 930-0194, Japan.

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http://dx.doi.org/10.1038/s41598-019-48678-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706391PMC
August 2019

Safety and effectiveness of ipragliflozin in elderly versus non-elderly Japanese type 2 diabetes mellitus patients: 12 month interim results of the STELLA-LONG TERM study.

Curr Med Res Opin 2019 11 29;35(11):1901-1910. Epub 2019 Aug 29.

Data Science, Development, Astellas Pharma Inc. , Tokyo , Japan.

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http://dx.doi.org/10.1080/03007995.2019.1647503DOI Listing
November 2019

M2-like macrophages serve as a niche for adipocyte progenitors in adipose tissue.

J Diabetes Investig 2019 Nov 5;10(6):1394-1400. Epub 2019 Aug 5.

First Department of Internal Medicine, University of Toyama, Toyama, Japan.

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http://dx.doi.org/10.1111/jdi.13114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825922PMC
November 2019

Mesenchymal stromal cells in bone marrow express adiponectin and are efficiently targeted by an adiponectin promoter-driven Cre transgene.

Int Immunol 2019 10;31(11):729-742

Laboratory of Immune Regulation, Department of Virus Research, Institute of Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1093/intimm/dxz042DOI Listing
October 2019

Implications of altered NAD metabolism in metabolic disorders.

J Biomed Sci 2019 May 11;26(1):34. Epub 2019 May 11.

Department of Metabolism and Nutrition, Graduate School of Medicine and Pharmaceutical Science for Research, University of Toyama, 2630 Sugitani, Toyama, Toyama, 930-0194, Japan.

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http://dx.doi.org/10.1186/s12929-019-0527-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511662PMC
May 2019

Clinical Parameters for Predicting the Survival in Patients with Squamous and Non-squamous-cell NSCLC Receiving PD-1 Inhibitor Therapy.

Pathol Oncol Res 2020 Jan 19;26(1):327-333. Epub 2018 Sep 19.

First Department of Internal Medicine, Toyama University Hospital, Sugitani 2630, Toyama City, 930-0194, Japan.

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http://dx.doi.org/10.1007/s12253-018-0473-xDOI Listing
January 2020

Deletion of PHGDH in adipocytes improves glucose intolerance in diet-induced obese mice.

Biochem Biophys Res Commun 2018 09 1;504(1):309-314. Epub 2018 Sep 1.

Department of Metabolism and Nutrition, Graduate School of Medicine and Pharmaceutical Science for Research, University of Toyama, Toyama, 930-0194, Japan; Institute of Natural Medicine, University of Toyama, Toyama, 930-0194, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X183188
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http://dx.doi.org/10.1016/j.bbrc.2018.08.180DOI Listing
September 2018

Autoantibodies reactive to PEP08 are clinically related with morbidity and severity of interstitial lung disease in connective tissue diseases.

Eur J Immunol 2018 10 25;48(10):1717-1727. Epub 2018 Jul 25.

Department of Immunology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan.

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http://dx.doi.org/10.1002/eji.201747381DOI Listing
October 2018

Urinary afamin levels are associated with the progression of diabetic nephropathy.

Diabetes Res Clin Pract 2019 Jan 6;147:37-46. Epub 2018 Mar 6.

Department of Diabetic Complications, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.diabres.2018.02.034DOI Listing
January 2019

SIRT1 and FOXO1 mRNA expression in PBMC correlates to physical activity in COPD patients.

Int J Chron Obstruct Pulmon Dis 2017 3;12:3237-3244. Epub 2017 Nov 3.

First Department of Internal Medicine, Faculty of Medicine, University of Toyama, Sugitani, Toyama, Toyama, Japan.

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http://dx.doi.org/10.2147/COPD.S144969DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680968PMC
July 2018

Sodium-glucose cotransporter 2 inhibitor, tofogliflozin, shows better improvements of blood glucose and insulin secretion in patients with high insulin levels at baseline.

J Diabetes Investig 2018 Jul 13;9(4):862-869. Epub 2017 Nov 13.

Department of Internal Medicine, Kawasaki Medical School, Okayama, Japan.

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http://dx.doi.org/10.1111/jdi.12761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031493PMC
July 2018

Reduced serum level of leukocyte cell-derived chemotaxin 2 is associated with the presence of diabetic retinopathy.

Clin Chim Acta 2016 Dec 29;463:145-149. Epub 2016 Oct 29.

Department of Diabetic Complications, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, Tokyo 162-8655, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.cca.2016.10.031DOI Listing
December 2016

M2 macrophages in metabolism.

Diabetol Int 2016 Dec 1;7(4):342-351. Epub 2016 Nov 1.

First Department of Internal Medicine, Graduate School of Medicine and Pharmaceutical Sciences for Research, University of Toyama, 2630 Sugitani, Toyama City, Toyama 930-0194 Japan.

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http://dx.doi.org/10.1007/s13340-016-0290-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224974PMC
December 2016

[Pioglitazone and the risk of bladder cancer].

Nihon Rinsho 2016 Apr;74 Suppl 2:442-6

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April 2016

Plasma neuron-specific enolase level as a prognostic marker in patients with non-small cell lung cancer receiving gefitinib.

Mol Clin Oncol 2015 Jul 14;3(4):802-806. Epub 2015 May 14.

Department of Diagnostic Pathology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Toyama 930-0194, Japan.

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http://dx.doi.org/10.3892/mco.2015.568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486842PMC
July 2015

Replication Study in a Japanese Population to Evaluate the Association between 10 SNP Loci, Identified in European Genome-Wide Association Studies, and Type 2 Diabetes.

PLoS One 2015 7;10(5):e0126363. Epub 2015 May 7.

Laboratory for Endocrinology, Metabolism and Kidney Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan; Department of Advanced Genomic and Laboratory Medicine, Graduate School of Medicine, University of the Ryukyus, Nishihara, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0126363PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423838PMC
April 2016

SIRT1-Mediated eNAMPT Secretion from Adipose Tissue Regulates Hypothalamic NAD+ and Function in Mice.

Cell Metab 2015 May 23;21(5):706-17. Epub 2015 Apr 23.

Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2015.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426056PMC
May 2015

Monoclonal antibody against citrullinated peptides obtained from rheumatoid arthritis patients reacts with numerous citrullinated microbial and food proteins.

Arthritis Rheumatol 2015 May;67(8):2020-31

Dana-Farber Cancer Institute, Boston, Massachusetts), Hiroshi Hamana, PhD, Hirofumi Taki, MD, PhD, Kazuyuki Tobe, MD, PhD, Eiji Sugiyama, MD, PhD (current address: Hiroshima University Hospital, Hiroshima, Japan), Johji Imura, MD, PhD, Hiroyuki Kishi, PhD, Atsushi Muraguchi, MD, PhD: University of Toyama Graduate School of Medicine and Pharmaceutical Sciences, Sugitani Campus, Toyama, Japan.

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http://dx.doi.org/10.1002/art.39161DOI Listing
May 2015

Thymoma with autoimmune hemolytic anemia.

Case Rep Oncol 2014 Sep-Dec;7(3):764-8. Epub 2014 Nov 19.

First Department of Medicine, Toyama University Hospital, Toyama, Japan.

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http://dx.doi.org/10.1159/000369491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322698PMC
February 2015

In vivo depletion of CD206+ M2 macrophages exaggerates lung injury in endotoxemic mice.

Am J Pathol 2015 Jan 27;185(1):162-71. Epub 2014 Oct 27.

Department of Molecular and Medical Pharmacology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2014.09.005DOI Listing
January 2015

Primary pulmonary lymphoma presenting with multiple lung nodules.

Am J Respir Crit Care Med 2014 Nov;190(9):e30-1

1 First Department of Internal Medicine and.

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http://dx.doi.org/10.1164/rccm.201401-0086IMDOI Listing
November 2014

Accidental cannulation of a femoral central venous catheter into the iliolumbar vein: incidental detection by bone scintigraphy.

Clin Nucl Med 2015 Feb;40(2):182-3

From the First Department of Internal Medicine, University of Toyama, Toyama, Toyama, Japan.

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http://dx.doi.org/10.1097/RLU.0000000000000551DOI Listing
February 2015

Usefulness of the Palliative Prognostic Index in patients with lung cancer.

Med Oncol 2014 Sep 10;31(9):154. Epub 2014 Aug 10.

First Department of Internal Medicine, Faculty of Medicine, University of Toyama, Sugitani 2630, Toyama City, 930-0194, Japan,

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http://dx.doi.org/10.1007/s12032-014-0154-xDOI Listing
September 2014

Pulmonary reversed halo sign as a presenting manifestation of rheumatoid arthritis.

Joint Bone Spine 2015 May 21;82(3):207. Epub 2014 Jul 21.

First Department of Internal Medicine, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan.

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http://dx.doi.org/10.1016/j.jbspin.2014.06.002DOI Listing
May 2015

Pseudo-Behçet's disease associated with tuberculosis: a case report and review of the literature.

Rheumatol Int 2014 Oct 29;34(10):1471-4. Epub 2014 Mar 29.

First Department of Internal Medicine, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan.

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http://dx.doi.org/10.1007/s00296-014-2998-yDOI Listing
October 2014

Long-term safety and efficacy of tofogliflozin, a selective inhibitor of sodium-glucose cotransporter 2, as monotherapy or in combination with other oral antidiabetic agents in Japanese patients with type 2 diabetes mellitus: multicenter, open-label, randomized controlled trials.

Expert Opin Pharmacother 2014 Apr 11;15(6):749-66. Epub 2014 Feb 11.

Yamaguchi University Graduate School of Medicine, Division of Endocrinology, Metabolism, Hematological Science and Therapeutics , 1-1-1 Minami-Kogushi, Ube, Yamaguchi 755-8505 , Japan +81 836 22 2250 (office) ; +81 836 22 2256 ;

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http://dx.doi.org/10.1517/14656566.2014.887680DOI Listing
April 2014

Replication study for the association of 9 East Asian GWAS-derived loci with susceptibility to type 2 diabetes in a Japanese population.

PLoS One 2013 25;8(9):e76317. Epub 2013 Sep 25.

Laboratory for Endocrinology, Metabolism and Kidney Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan ; Department of Internal Medicine, Division of Metabolism and Endocrinology, St. Marianna University School of Medicine, Kawasaki, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0076317PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783369PMC
July 2014

Assessing the clinical utility of a genetic risk score constructed using 49 susceptibility alleles for type 2 diabetes in a Japanese population.

J Clin Endocrinol Metab 2013 Oct 16;98(10):E1667-73. Epub 2013 Aug 16.

Laboratory for Endocrinology, Metabolism, and Kidney Diseases, RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1210/jc.2013-1642DOI Listing
October 2013

Mediator complex recruits epigenetic regulators via its two cyclin-dependent kinase subunits to repress transcription of immune response genes.

J Biol Chem 2013 Jul 9;288(29):20955-65. Epub 2013 Jun 9.

Laboratory of Gene Regulation, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan.

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http://dx.doi.org/10.1074/jbc.M113.486746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774365PMC
July 2013

Impact of divergent effects of astaxanthin on insulin signaling in L6 cells.

Endocrinology 2013 Aug 28;154(8):2600-12. Epub 2013 May 28.

The First Department of Internal Medicine, Faculty of Medicine, University of Toyama, Toyama, Japan.

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http://dx.doi.org/10.1210/en.2012-2198DOI Listing
August 2013

Cytophagic histiocytic panniculitis in a 74-year-old man.

Age Ageing 2013 May 18;42(3):409-10. Epub 2013 Mar 18.

First Department of Internal Medicine, University of Toyama, 2630 Sugitani, Toyama, Toyama 930-0194, Japan.

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http://dx.doi.org/10.1093/ageing/aft034DOI Listing
May 2013

Elevated serum procalcitonin in anaphylaxis.

J Antimicrob Chemother 2013 Jul 10;68(7):1689-90. Epub 2013 Mar 10.

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http://dx.doi.org/10.1093/jac/dkt076DOI Listing
July 2013