Kazuyuki Ohmoto

Kazuyuki Ohmoto

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Kazuyuki Ohmoto

Kazuyuki Ohmoto

Publications by authors named "Kazuyuki Ohmoto"

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Synthesis and evaluation of a potent, well-balanced EP/EP dual agonist.

Bioorg Med Chem 2018 01 24;26(1):200-214. Epub 2017 Nov 24.

Medicinal Chemistry Research Laboratories, Ono Pharmaceutical Co., Ltd., 3-1-1 Sakurai, Shimamoto-cho, Mishima-gun, Osaka 618-8585, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2017.11.035DOI Listing
January 2018

Discovery of highly potent dual EP(2) and EP(3) agonists with subtype selectivity.

Bioorg Med Chem Lett 2016 Feb 12;26(3):1016-1019. Epub 2015 Dec 12.

Medicinal Chemistry Research Laboratories, Ono Pharmaceutical Co., Ltd, 3-1-1 Sakurai, Shimamoto-cho, Mishima-gun, Osaka 618-8585, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2015.12.039DOI Listing
February 2016

Combination therapy with ONO-KK1-300-01, a cathepsin K inhibitor, and parathyroid hormone results in additive beneficial effect on bone mineral density in ovariectomized rats.

J Bone Miner Metab 2016 Jan 12;34(1):33-40. Epub 2015 Mar 12.

Discovery Research Laboratories, Ono Pharmaceutical Co., Ltd., 3-1-1 Sakurai, Shimamoto-cho, Mishima-gun, Osaka, 618-8585, Japan.

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http://dx.doi.org/10.1007/s00774-014-0643-1DOI Listing
January 2016

Anti-stress effects of ONO-2952, a novel translocator protein 18 kDa antagonist, in rats.

Neuropharmacology 2015 Dec 17;99:51-66. Epub 2015 Jul 17.

Discovery Research Laboratories I, ONO Pharmaceutical Co., Ltd, 3-1-1 Sakurai, Shimamoto-cho, Mishima-gun, Osaka, 618-8585, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2015.07.011DOI Listing
December 2015

ONO-5334, a cathepsin K inhibitor, improves bone strength by preferentially increasing cortical bone mass in ovariectomized rats.

J Bone Miner Metab 2014 Nov 8;32(6):645-52. Epub 2013 Dec 8.

Minase Research Institute, Ono Pharmaceutical Co., Ltd., 3-1-1 Sakurai Shimamoto-cho Mishima-gun, Osaka, 618-8585, Japan.

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http://dx.doi.org/10.1007/s00774-013-0542-xDOI Listing
November 2014

Indole diterpene synthetic studies. Total synthesis of (+)-nodulisporic acid F and construction of the heptacyclic cores of (+)-nodulisporic acids A and B and (-)-nodulisporic acid D.

J Org Chem 2007 Jun 19;72(13):4596-610. Epub 2007 May 19.

Department of Chemistry, Monell Chemical Senses Center and Laboratory for Research on the Structure of Matter, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1021/jo062422iDOI Listing
June 2007

Indole diterpene synthetic studies: development of a second-generation synthetic strategy for (+)-nodulisporic acids A and B.

J Org Chem 2007 Jun 19;72(13):4611-20. Epub 2007 May 19.

Department of Chemistry, Monell Chemical Senses Center and Laboratory for Research on the Structure of Matter, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1021/jo062423aDOI Listing
June 2007