Kazutoshi Mori

Kazutoshi Mori

UNVERIFIED PROFILE

Are you Kazutoshi Mori?   Register this Author

Register author
Kazutoshi Mori

Kazutoshi Mori

Publications by authors named "Kazutoshi Mori"

Are you Kazutoshi Mori?   Register this Author

89Publications

1250Reads

10Profile Views

Cartilage endoplasmic reticulum stress may influence the onset but not the progression of experimental osteoarthritis.

Arthritis Res Ther 2019 Sep 11;21(1):206. Epub 2019 Sep 11.

Wellcome Trust Centre for Cell-Matrix Research, Faculty of Biology, Medicine and Health and Manchester Academic Health Science Centre, The University of Manchester, Manchester, M13 9PT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13075-019-1988-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737683PMC
September 2019

Environmental pollution cost analyses of biodiesel and diesel fuels for a diesel engine.

J Environ Manage 2019 Aug 13;243:218-226. Epub 2019 May 13.

Department of Mechanical and Precision System Engineering, Faculty of Science and Engineering, Teikyo University, 320-8551, Utsunomiya, Tochigi, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jenvman.2019.05.002DOI Listing
August 2019

ATF6α downregulation of PPARα promotes lipotoxicity-induced tubulointerstitial fibrosis.

Kidney Int 2019 03 11;95(3):577-589. Epub 2019 Jan 11.

Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.kint.2018.09.023DOI Listing
March 2019

A Collection of Transgenic Medaka Strains for Efficient Site-Directed Transgenesis Mediated by phiC31 Integrase.

G3 (Bethesda) 2018 07 31;8(8):2585-2593. Epub 2018 Jul 31.

Department of Biophysics, Graduate School of Science.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1534/g3.118.200130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071608PMC
July 2018

SEL1L-dependent Substrates Require Derlin2/3 and Herp1/2 for Endoplasmic Reticulum-associated Degradation.

Cell Struct Funct 2017 Jul 26;42(2):81-94. Epub 2017 May 26.

Department of Biophysics, Graduate School of Science, Kyoto University.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1247/csf.17007DOI Listing
July 2017

Atf6α deficiency suppresses microglial activation and ameliorates pathology of experimental autoimmune encephalomyelitis.

J Neurochem 2016 12 18;139(6):1124-1137. Epub 2016 Jul 18.

Department of Neuroanatomy, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jnc.13714DOI Listing
December 2016

The unfolded protein response: the dawn of a new field.

Authors:
Kazutoshi Mori

Proc Jpn Acad Ser B Phys Biol Sci 2015 ;91(9):469-80

Department of Biophysics, Graduate School of Science, Kyoto University.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2183/pjab.91.469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754504PMC
August 2016

Unfolded protein response in hypothalamic cultures of wild-type and ATF6α-knockout mice.

Neurosci Lett 2016 Jan 18;612:199-203. Epub 2015 Dec 18.

Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neulet.2015.12.031DOI Listing
January 2016

Deletion of Atf6α enhances kainate-induced neuronal death in mice.

Neurochem Int 2016 Jan 25;92:67-74. Epub 2015 Dec 25.

Department of Neuroanatomy, Graduate School of Medical Science, Kanazawa University, Japan; CREST (Core Research for Evolutionary Science and Technology), JST (Japan Science and Technology Agency), Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuint.2015.12.009DOI Listing
January 2016

Endoplasmic Reticulum (ER) Stress Induces Sirtuin 1 (SIRT1) Expression via the PI3K-Akt-GSK3β Signaling Pathway and Promotes Hepatocellular Injury.

J Biol Chem 2015 Dec 23;290(51):30366-74. Epub 2015 Oct 23.

From the Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto, 862-0973, Japan,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M115.664169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683260PMC
December 2015

XBP 1-Deficiency Abrogates Neointimal Lesion of Injured Vessels Via Cross Talk With the PDGF Signaling.

Arterioscler Thromb Vasc Biol 2015 Oct 27;35(10):2134-44. Epub 2015 Aug 27.

From the Cardiovascular Division, King's College London BHF Centre, London, United Kingdom (L.Z., Y.L., J.Y., A.Z., X.Y., M.M., Y.H., Q.X.); Institute of Bioengineering (J.Y., W.W.) and Centre for Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry (Q.X.), Queen Mary University of London, London, United Kingdom; Department of Emergency Medicine, The Second Affiliated Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an, China (G.W.); Centre for Experimental Medicine, Queen's University Belfast, Belfast, United Kingdom (A.M.); and Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto, Japan (K.M.).

View Article

Download full-text PDF

Source
http://atvb.ahajournals.org/content/35/10/2134.full.pdf
Web Search
http://atvb.ahajournals.org/lookup/doi/10.1161/ATVBAHA.115.3
Publisher Site
http://dx.doi.org/10.1161/ATVBAHA.115.305420DOI Listing
October 2015

Activation of the Unfolded Protein Response in Sporadic Inclusion-Body Myositis but Not in Hereditary GNE Inclusion-Body Myopathy.

J Neuropathol Exp Neurol 2015 Jun;74(6):538-46

From the USC Neuromuscular Center, Department of Neurology, University of Southern California Keck School of Medicine, Good Samaritan Hospital, Los Angeles, California (AN, CDA, WKE, MC, VA); and Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto, Japan (SA, KM).

View Article

Download full-text PDF

Source
http://jnen.oxfordjournals.org/content/jnen/74/6/538.full.pd
Web Search
http://jnen.oxfordjournals.org/lookup/doi/10.1097/NEN.000000
Publisher Site
http://dx.doi.org/10.1097/NEN.0000000000000196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506930PMC
June 2015

Deletion of Atf6α impairs astroglial activation and enhances neuronal death following brain ischemia in mice.

J Neurochem 2015 Feb 6;132(3):342-53. Epub 2015 Jan 6.

Department of Neurosurgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa City, Ishikawa, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jnc.12981DOI Listing
February 2015

Activating transcription factor 6α is required for the vasopressin neuron system to maintain water balance under dehydration in male mice.

Endocrinology 2014 Dec 9;155(12):4905-14. Epub 2014 Sep 9.

Departments of Endocrinology and Diabetes (Y.A., D.H., W.L., Y.M., H.S., M.G., R.B., Y.S., Y.O., H.A.) and Pathology (N.A., M.T.), Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan; Institute of Immunology Co., Ltd (A.S.), 1198-4 Iwazo, Utsunomiya 321-0973, Japan; Institute for Genome Research (S.O.), University of Tokushima, Tokushima 770-8503, Japan; and Department of Biophysics (K.M.), Graduate School of Science, Kyoto University, Kyoto 606-8502, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2014-1522DOI Listing
December 2014

Lasker Award winner Kazutoshi Mori.

Authors:
Kazutoshi Mori

Nat Med 2014 Oct;20(10):1115-7

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nm.3682DOI Listing
October 2014

EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step.

J Cell Biol 2014 Aug;206(3):347-56

Department of Biophysics, Graduate School of Science, and Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto 606-8502, Japan

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1083/jcb.201404075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121980PMC
August 2014

The antipsychotic olanzapine induces apoptosis in insulin-secreting pancreatic β cells by blocking PERK-mediated translational attenuation.

Cell Struct Funct 2013 28;38(2):183-95. Epub 2013 Jun 28.

Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto 606-8502, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1247/csf.13012DOI Listing
April 2014

The specialized unfolded protein response of B lymphocytes: ATF6α-independent development of antibody-secreting B cells.

Mol Immunol 2012 Jul 1;51(3-4):347-55. Epub 2012 May 1.

Department of Microbiology and Immunology, College of Medicine, University of South Alabama, 5851 USA Drive North, Mobile, AL 36688, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molimm.2012.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358488PMC
July 2012

An IFN-γ-stimulated ATF6-C/EBP-β-signaling pathway critical for the expression of Death Associated Protein Kinase 1 and induction of autophagy.

Proc Natl Acad Sci U S A 2012 Jun 13;109(26):10316-21. Epub 2012 Jun 13.

Department of Microbiology and Immunology, Center for Vaccine Development, and Marlene and Stewart Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1119273109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387052PMC
June 2012

Vertebrate unfolded protein response: mammalian signaling pathways are conserved in Medaka fish.

Cell Struct Funct 2011 8;36(2):247-59. Epub 2011 Nov 8.

Department of Biophysics, Graduate School of Science, Kyoto University, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1247/csf.11036DOI Listing
April 2012

SEL1L is required for endoplasmic reticulum-associated degradation of misfolded luminal proteins but not transmembrane proteins in chicken DT40 cell line.

Cell Struct Funct 2011 20;36(2):187-95. Epub 2011 Aug 20.

Department of Biophysics, Graduate School of Science, Kyoto University, Sakyo-ku, Kyoto, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1247/csf.11018DOI Listing
December 2011

Luminal domain of ATF6 alone is sufficient for sensing endoplasmic reticulum stress and subsequent transport to the Golgi apparatus.

Cell Struct Funct 2011 8;36(1):35-47. Epub 2010 Dec 8.

Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto 606-8502, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1247/csf.10010DOI Listing
August 2011

The endoplasmic reticulum stress sensor, ATF6α, protects against neurotoxin-induced dopaminergic neuronal death.

J Biol Chem 2011 Mar 3;286(10):7947-57. Epub 2010 Dec 3.

Department of Neurology, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M110.156430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048681PMC
March 2011

Endoplasmic reticulum stress increases the expression and function of toll-like receptor-2 in epithelial cells.

Biochem Biophys Res Commun 2010 Nov 8;402(2):235-40. Epub 2010 Oct 8.

Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Global COE Cell Fate Regulation Research and Education Unit, Kumamoto University, 5-1 Oe-Honmachi, Kumamoto 862-0973, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2010.09.132DOI Listing
November 2010

Divest yourself of a preconceived idea: transcription factor ATF6 is not a soluble protein!

Authors:
Kazutoshi Mori

Mol Biol Cell 2010 May 10;21(9):1435-8. Epub 2010 Mar 10.

Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto 606-8502, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1091/mbc.e09-07-0600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861603PMC
May 2010

Signalling pathways in the unfolded protein response: development from yeast to mammals.

Authors:
Kazutoshi Mori

J Biochem 2009 Dec 27;146(6):743-50. Epub 2009 Oct 27.

Department of Biophysics, Graduate School of Science, Kyoto University, Kitashirakawa-Oiwake, Sakyo-ku, Kyoto 606-8502, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jb/mvp166DOI Listing
December 2009

The sterol-sensing endoplasmic reticulum (ER) membrane protein TRC8 hampers ER to Golgi transport of sterol regulatory element-binding protein-2 (SREBP-2)/SREBP cleavage-activated protein and reduces SREBP-2 cleavage.

J Biol Chem 2009 Oct 25;284(42):28995-9004. Epub 2009 Aug 25.

Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M109.041376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781446PMC
October 2009

Unconventional splicing of XBP1 mRNA occurs in the cytoplasm during the mammalian unfolded protein response.

J Cell Sci 2009 Aug 21;122(Pt 16):2877-86. Epub 2009 Jul 21.

Department of Biophysics, Graduate School of Science, Kyoto University, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/jcs.040584DOI Listing
August 2009

The anti-apoptotic role of the unfolded protein response in Bcr-Abl-positive leukemia cells.

Leuk Res 2009 Jul 23;33(7):924-8. Epub 2009 Feb 23.

Department of Bio-Signal Analysis, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi 755-8505, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.leukres.2009.01.027DOI Listing
July 2009

pXBP1(U), a negative regulator of the unfolded protein response activator pXBP1(S), targets ATF6 but not ATF4 in proteasome-mediated degradation.

Cell Struct Funct 2009 1;34(1):1-10. Epub 2009 Jan 1.

Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1247/csf.06028DOI Listing
April 2009

p31 deficiency influences endoplasmic reticulum tubular morphology and cell survival.

Mol Cell Biol 2009 Apr 2;29(7):1869-81. Epub 2009 Feb 2.

Laboratory of Molecular Traffic, Department of Molecular and Cellular Biology, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Gunma 371-8512, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/MCB.01089-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655616PMC
April 2009

Human HRD1 promoter carries a functional unfolded protein response element to which XBP1 but not ATF6 directly binds.

J Biochem 2008 Oct 29;144(4):477-86. Epub 2008 Jul 29.

Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jb/mvn091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755579PMC
October 2008

ATF6 is a transcription factor specializing in the regulation of quality control proteins in the endoplasmic reticulum.

Cell Struct Funct 2008 18;33(1):75-89. Epub 2008 Mar 18.

Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1247/csf.07044DOI Listing
June 2008

Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation.

J Biol Chem 2007 Oct 8;282(40):29264-72. Epub 2007 Aug 8.

Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan.

View Article

Download full-text PDF

Source
http://www.jbc.org/lookup/doi/10.1074/jbc.M705038200
Publisher Site
http://dx.doi.org/10.1074/jbc.M705038200DOI Listing
October 2007

Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1.

Dev Cell 2007 Sep;13(3):365-76

Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto 606-8502, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.devcel.2007.07.018DOI Listing
September 2007

XBP1 is critical to protect cells from endoplasmic reticulum stress: evidence from Site-2 protease-deficient Chinese hamster ovary cells.

Cell Struct Funct 2006 17;31(2):117-25. Epub 2006 Nov 17.

Department of Biophysics, Graduate School of Science, Kyoto University, Kitashirakawa-Oiwake, Sakyo-ku, Kyoto 606-8502, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1247/csf.06016DOI Listing
June 2007

Analysis of ATF6 activation in Site-2 protease-deficient Chinese hamster ovary cells.

Cell Struct Funct 2006 17;31(2):109-16. Epub 2006 Nov 17.

Department of Biophysics, Graduate School of Science, Kyoto University, Kitashirakawa-Oiwake, Sakyo-ku, Kyoto 606-8502, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1247/csf.06015DOI Listing
June 2007

Role of disulfide bridges formed in the luminal domain of ATF6 in sensing endoplasmic reticulum stress.

Mol Cell Biol 2007 Feb 13;27(3):1027-43. Epub 2006 Nov 13.

Department of Biophysics, Graduate School of Science, Kyoto University, Kitashirakawa-oiwake, Sakyo-ku, Kyoto 606-8502, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/MCB.00408-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1800683PMC
February 2007

Reduction of disulfide bridges in the lumenal domain of ATF6 in response to glucose starvation.

Cell Struct Funct 2006 28;31(2):127-34. Epub 2006 Nov 28.

Department of Biophysics, Graduate School of Science, Kyoto University, Kitashirakawa-Oiwake, Sakyo-ku, Kyoto 606-8502, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1247/csf.06024DOI Listing
December 2006

pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response.

J Cell Biol 2006 Feb 6;172(4):565-75. Epub 2006 Feb 6.

Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto 606-8502, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1083/jcb.200508145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063676PMC
February 2006

Transformation-associated gene regulation by ATF6alpha during hepatocarcinogenesis.

FEBS Lett 2006 Jan 9;580(1):184-90. Epub 2005 Dec 9.

Department of Biochemistry II, National Defense Medical College, 3-2 Namiki, Tokorozawa-shi, Saitama 359-8513, Japan.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1016/j.febslet.2005.11.072
Publisher Site
http://dx.doi.org/10.1016/j.febslet.2005.11.072DOI Listing
January 2006

Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation.

J Cell Biol 2006 Jan;172(3):383-93

Department of Molecular and Cellular Biology Institute for Frontier Medical Sciences, Graduate School of Science, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1083/jcb.200507057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063648PMC
January 2006

XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum.

J Cell Biol 2004 Oct 4;167(1):35-41. Epub 2004 Oct 4.

Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153, USA.

View Article

Download full-text PDF

Source
http://www.jcb.org/lookup/doi/10.1083/jcb.200406136
Publisher Site
http://dx.doi.org/10.1083/jcb.200406136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172532PMC
October 2004

A role for the unfolded protein response in optimizing antibody secretion.

Mol Immunol 2004 Jul;41(9):919-27

Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago 2160 South First Avenue, Maywood, IL 60153, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molimm.2004.04.023DOI Listing
July 2004

Activation of mammalian unfolded protein response is compatible with the quality control system operating in the endoplasmic reticulum.

Mol Biol Cell 2004 Jun 12;15(6):2537-48. Epub 2004 Mar 12.

Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto 606-8502, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1091/mbc.e03-09-0693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC420080PMC
June 2004

A cellular UDP-glucose deficiency causes overexpression of glucose/oxygen-regulated proteins independent of the endoplasmic reticulum stress elements.

J Biol Chem 2004 May 12;279(21):21724-31. Epub 2004 Mar 12.

Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-171 77 Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M312791200DOI Listing
May 2004

[Unfolded protein response as a quality control mechanism of proteins].

Authors:
Kazutoshi Mori

Tanpakushitsu Kakusan Koso 2004 May;49(7 Suppl):992-7

View Article

Download full-text PDF

Source
May 2004

Hepatitis C virus suppresses the IRE1-XBP1 pathway of the unfolded protein response.

J Biol Chem 2004 Apr 11;279(17):17158-64. Epub 2004 Feb 11.

Department of Microbiology and Program in Molecular Biology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M312144200DOI Listing
April 2004

The fusion oncoprotein PML-RARalpha induces endoplasmic reticulum (ER)-associated degradation of N-CoR and ER stress.

J Biol Chem 2004 Mar 29;279(12):11814-24. Epub 2003 Dec 29.

Laboratory of Molecular Genetics, RIKEN Tsukuba Institute, 3-1-1 Koyadai, Tsukuba, Ibaraki 305-0074, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M312121200DOI Listing
March 2004

The endoplasmic reticulum stress response is stimulated through the continuous activation of transcription factors ATF6 and XBP1 in Ins2+/Akita pancreatic beta cells.

Genes Cells 2004 Mar;9(3):261-70

Department of Molecular and Cellular Biology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8397, Japan.

View Article

Download full-text PDF

Source
March 2004

ATF6 modulates SREBP2-mediated lipogenesis.

EMBO J 2004 Feb 5;23(4):950-8. Epub 2004 Feb 5.

Division of Biomedical Sciences, University of California, Riverside, Riverside, CA 92521-0121, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.emboj.7600106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC381012PMC
February 2004

Autoregulation of the HAC1 gene is required for sustained activation of the yeast unfolded protein response.

Genes Cells 2004 Feb;9(2):95-104

HSP Research Institute, Kyoto 600-8813, Japan.

View Article

Download full-text PDF

Source
February 2004

Frame switch splicing and regulated intramembrane proteolysis: key words to understand the unfolded protein response.

Authors:
Kazutoshi Mori

Traffic 2003 Aug;4(8):519-28

Graduate School of Biostudies, Kyoto University, 46-29 Yoshida-Shimoadachi, Sakyo-ku, Kyoto 606-8304, Japan.

View Article

Download full-text PDF

Source
August 2003

[Intracellular traffic of membrane-bound transcription factors].

Seikagaku 2003 Jun;75(6):506-11

Graduate School of Biostudies, Kyoto University, CREST, Japan Science and Technology Corporation, 46-29 Yoshida-Shimoadachi, Sakyo-ku, Kyoto 606-8304, Japan.

View Article

Download full-text PDF

Source
June 2003

Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis.

J Hepatol 2003 May;38(5):605-14

Department of Microbiology and Cell Biology, The Tokyo Metropolitan Institute of Medical Science, 3-18-22 Honkomagome, Bunkyo-ku, Tokyo 113-8613, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0168-8278(03)00029-1DOI Listing
May 2003

The cargo receptor ERGIC-53 is a target of the unfolded protein response.

Biochem Biophys Res Commun 2003 May;304(4):599-604

Department of Pharmacology and Neurobiology, Biozentrum, University of Basel, Klingelbergstrasse 70, CH-4056 Basel, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0006-291x(03)00634-xDOI Listing
May 2003

Dysfunction of the unfolded protein response during global brain ischemia and reperfusion.

J Cereb Blood Flow Metab 2003 Apr;23(4):462-71

Department of Emergency Medicine, Wayne State University, Detroit, Michigan, U.S.A.

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1097/01.WCB.0000056064.25
Publisher Site
http://dx.doi.org/10.1097/01.WCB.0000056064.25434.CADOI Listing
April 2003

A time-dependent phase shift in the mammalian unfolded protein response.

Dev Cell 2003 Feb;4(2):265-71

Graduate School of Biostudies, Kyoto University, Kyoto 606-8304, Japan.

View Article

Download full-text PDF

Source
February 2003

Rapostlin is a novel effector of Rnd2 GTPase inducing neurite branching.

J Biol Chem 2002 Nov 18;277(47):45428-34. Epub 2002 Sep 18.

Laboratory of Molecular Neurobiology, Graduate School of Biostudies, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan.

View Article

Download full-text PDF

Source
http://www.jbc.org/lookup/doi/10.1074/jbc.M208090200
Publisher Site
http://dx.doi.org/10.1074/jbc.M208090200DOI Listing
November 2002

Developmental changes in expression of small GTPase RhoG mRNA in the rat brain.

Brain Res Mol Brain Res 2002 Oct;106(1-2):145-50

Laboratory of Molecular Neurobiology, Graduate School of Biostudies, Kyoto University, Sakyo-ku, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0169-328x(02)00413-8DOI Listing
October 2002

Hepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathway.

J Virol 2002 Aug;76(15):7453-9

Department of Microbiology and Program in Molecular Biology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC136367PMC
http://dx.doi.org/10.1128/jvi.76.15.7453-7459.2002DOI Listing
August 2002

Galpha(12) and Galpha(13) interact with Ser/Thr protein phosphatase type 5 and stimulate its phosphatase activity.

Curr Biol 2002 Aug;12(15):1353-8

Laboratory of Molecular Neurobiology, Graduate School of Biostudies, Kyoto University, Sakyo-ku, 606-8502, Kyoto, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0960-9822(02)01034-5DOI Listing
August 2002

Vps4-A (vacuolar protein sorting 4-A) is a binding partner for a novel Rho family GTPase, Rnd2.

Biochem J 2002 Jul;365(Pt 2):349-53

Laboratory of Molecular Neurobiology, Graduate School of Biostudies, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan.

View Article

Download full-text PDF

Source
http://biochemj.org/lookup/doi/10.1042/bj20020062
Publisher Site
http://dx.doi.org/10.1042/BJ20020062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1222680PMC
July 2002

Socius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers.

Mol Cell Biol 2002 May;22(9):2952-64

Laboratory of Molecular Neurobiology, Graduate School of Biostudies, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC133765PMC
http://dx.doi.org/10.1128/mcb.22.9.2952-2964.2002DOI Listing
May 2002

Nitric oxide-induced apoptosis in RAW 264.7 macrophages is mediated by endoplasmic reticulum stress pathway involving ATF6 and CHOP.

J Biol Chem 2002 Apr 22;277(14):12343-50. Epub 2002 Jan 22.

Department of Molecular Genetics, Kumamoto University School of Medicine, Kumamoto 860-0811, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M107988200DOI Listing
April 2002