Kazumasa Wakamatsu

Kazumasa Wakamatsu

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Kazumasa Wakamatsu

Publications by authors named "Kazumasa Wakamatsu"

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The role of hydrogen peroxide and singlet oxygen in the photodegradation of melanin.

Photochem Photobiol Sci 2020 May 20;19(5):654-667. Epub 2020 Apr 20.

Department of Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.

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http://dx.doi.org/10.1039/c9pp00481eDOI Listing
May 2020

The influence of iron on selected properties of synthetic pheomelanin.

Cell Biochem Biophys 2020 May 24. Epub 2020 May 24.

Department of Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.

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http://dx.doi.org/10.1007/s12013-020-00918-1DOI Listing
May 2020

Kojic acid alters pheomelanin content in human induced pluripotent stem cell-derived melanocytes.

J Dermatol 2020 Apr 17;47(4):435-436. Epub 2020 Feb 17.

Division of Dermatology, Tohoku Medical and Pharmaceutical University, Sendai, Japan.

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http://dx.doi.org/10.1111/1346-8138.15260DOI Listing
April 2020

Significance of 5--Cysteinyldopa as a Marker for Melanoma.

Int J Mol Sci 2020 Jan 9;21(2). Epub 2020 Jan 9.

Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-8556, Japan.

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http://dx.doi.org/10.3390/ijms21020432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013534PMC
January 2020

Taphonomic experiments resolve controls on the preservation of melanosomes and keratinous tissues in feathers.

Palaeontology 2020 Jan 19;63(1):103-115. Epub 2019 Sep 19.

Department of Chemistry Fujita Health University School of Health Sciences Toyoake Aichi Japan.

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http://dx.doi.org/10.1111/pala.12445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988486PMC
January 2020

Tyrosinase-catalyzed oxidation of resveratrol produces a highly reactive ortho-quinone: Implications for melanocyte toxicity.

Pigment Cell Melanoma Res 2019 11 10;32(6):766-776. Epub 2019 Jul 10.

Department of Chemistry, Fujita Health University School of Medical Sciences, Toyoake, Aichi, Japan.

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http://dx.doi.org/10.1111/pcmr.12808DOI Listing
November 2019

Synchrotron X-ray absorption spectroscopy of melanosomes in vertebrates and cephalopods: implications for the affinity of .

Proc Biol Sci 2019 10 23;286(1913):20191649. Epub 2019 Oct 23.

School of Biological, Earth and Environmental Sciences, University College Cork, Distillery Fields, North Mall, Cork T23 TK30, Republic of Ireland.

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http://dx.doi.org/10.1098/rspb.2019.1649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834042PMC
October 2019

Tissue-specific geometry and chemistry of modern and fossilized melanosomes reveal internal anatomy of extinct vertebrates.

Proc Natl Acad Sci U S A 2019 09 19;116(36):17880-17889. Epub 2019 Aug 19.

Department of Chemistry, Fujita Health University School of Health Sciences, 470-1192 Toyoake, Aichi, Japan.

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http://dx.doi.org/10.1073/pnas.1820285116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731645PMC
September 2019

Effects of Aging on Hair Color, Melanosome Morphology, and Melanin Composition in Japanese Females.

Int J Mol Sci 2019 Jul 31;20(15). Epub 2019 Jul 31.

Department of Chemistry, Fujita Health University School of Medical Sciences, Toyoake, Aichi 470-1192, Japan.

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http://dx.doi.org/10.3390/ijms20153739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696507PMC
July 2019

Photobleaching of pheomelanin increases its phototoxic potential: Physicochemical studies of synthetic pheomelanin subjected to aerobic photolysis.

Pigment Cell Melanoma Res 2019 05 11;32(3):359-372. Epub 2018 Dec 11.

Department of Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.

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http://doi.wiley.com/10.1111/pcmr.12752
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http://dx.doi.org/10.1111/pcmr.12752DOI Listing
May 2019

Visible light accelerates the ultraviolet A-induced degradation of eumelanin and pheomelanin.

Pigment Cell Melanoma Res 2019 05 11;32(3):441-447. Epub 2018 Dec 11.

Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Japan.

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http://dx.doi.org/10.1111/pcmr.12754DOI Listing
May 2019

Pheomelanin pigment remnants mapped in fossils of an extinct mammal.

Nat Commun 2019 05 21;10(1):2250. Epub 2019 May 21.

University of Manchester, School of Earth and Environmental Sciences, Williamson Research Centre for Molecular Environmental Science & Interdisciplinary Centre for Ancient Life, Manchester, M13 9PL, UK.

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http://dx.doi.org/10.1038/s41467-019-10087-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529433PMC
May 2019

The Oxidative Pathway to Dopamine-Protein Conjugates and Their Pro-Oxidant Activities: Implications for the Neurodegeneration of Parkinson's Disease.

Int J Mol Sci 2019 May 25;20(10). Epub 2019 May 25.

Department of Chemistry, Fujita Health University School of Medical Sciences, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi 470-1192, Japan.

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http://dx.doi.org/10.3390/ijms20102575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567298PMC
May 2019

Ethanol induces skin hyperpigmentation in mice with aldehyde dehydrogenase 2 deficiency.

Chem Biol Interact 2019 Apr 2;302:61-66. Epub 2019 Feb 2.

Department of Dermatology, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1016/j.cbi.2019.01.035DOI Listing
April 2019

Eumelanin levels in rufous feathers explain plasma testosterone levels and survival in swallows.

Ecol Evol 2019 Mar 30;9(5):2755-2764. Epub 2019 Jan 30.

Department of Chemistry Fujita Health University School of Health Sciences Toyoake Aichi Japan.

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http://dx.doi.org/10.1002/ece3.4946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405925PMC
March 2019

Linking a mutation to survival in wild mice.

Science 2019 02 31;363(6426):499-504. Epub 2019 Jan 31.

Department of Organismic and Evolutionary Biology, Museum of Comparative Zoology, Harvard University, Cambridge, MA USA.

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http://dx.doi.org/10.1126/science.aav3824DOI Listing
February 2019

Males with More Pheomelanin Have a Lower Oxidative Balance in Asian Barn Swallows (Hirundo rustica gutturalis).

Zoolog Sci 2018 12;35(6):505-513

2 Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Aichi 470-1192, Japan.

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http://dx.doi.org/10.2108/zs170204DOI Listing
December 2018

Raman spectroscopy quantification of eumelanin subunits in natural unaltered pigments.

Pigment Cell Melanoma Res 2018 11 24;31(6):673-682. Epub 2018 May 24.

Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Japan.

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http://dx.doi.org/10.1111/pcmr.12707DOI Listing
November 2018

Serum 5-S-cysteinyldopa behavior in the early phase of nivolumab treatment of 12 melanoma patients.

J Dermatol 2018 Nov 25;45(11):1340-1344. Epub 2018 Aug 25.

Department of Dermatology, Shinshu University School of Medicine, Matsumoto, Japan.

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http://dx.doi.org/10.1111/1346-8138.14605DOI Listing
November 2018

Differential gene regulation underlies variation in melanic plumage coloration in the dark-eyed junco (Junco hyemalis).

Mol Ecol 2018 11 22;27(22):4501-4515. Epub 2018 Oct 22.

National Museum of Natural Sciences, Spanish National Research Council (CSIC), Madrid, Spain.

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http://dx.doi.org/10.1111/mec.14878DOI Listing
November 2018

The Pro-Oxidant Activity of Pheomelanin is Significantly Enhanced by UVA Irradiation: Benzothiazole Moieties Are More Reactive than Benzothiazine Moieties.

Int J Mol Sci 2018 Sep 23;19(10). Epub 2018 Sep 23.

Department of Chemistry, Fujita Health University School of Health Sciences, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi 470-1192, Japan.

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http://dx.doi.org/10.3390/ijms19102889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213070PMC
September 2018

Molecular vibration as a novel explanatory mechanism for the expression of animal colouration.

Integr Biol (Camb) 2018 08 28;10(8):464-473. Epub 2018 Jun 28.

Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Aichi 470-1192, Japan.

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http://dx.doi.org/10.1039/c8ib00100fDOI Listing
August 2018

The potent pro-oxidant activity of rhododendrol-eumelanin is enhanced by ultraviolet A radiation.

Pigment Cell Melanoma Res 2018 07 12;31(4):523-528. Epub 2018 Mar 12.

Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Japan.

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http://dx.doi.org/10.1111/pcmr.12696DOI Listing
July 2018

Non-integumentary melanosomes can bias reconstructions of the colours of fossil vertebrates.

Nat Commun 2018 07 23;9(1):2878. Epub 2018 Jul 23.

Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Aichi, 470-1192, Japan.

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http://dx.doi.org/10.1038/s41467-018-05148-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056411PMC
July 2018

Photodegradation of Eumelanin and Pheomelanin and Its Pathophysiological Implications.

Photochem Photobiol 2018 05 26;94(3):409-420. Epub 2017 Oct 26.

Department of Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.

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http://dx.doi.org/10.1111/php.12837DOI Listing
May 2018

Insect cuticular melanins are distinctly different from those of mammalian epidermal melanins.

Pigment Cell Melanoma Res 2018 05 4;31(3):384-392. Epub 2017 Dec 4.

School of health Sciences, Fujita Health University, Toyoake, Japan.

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http://dx.doi.org/10.1111/pcmr.12672DOI Listing
May 2018

Acid hydrolysis reveals a low but constant level of pheomelanin in human black to brown hair.

Pigment Cell Melanoma Res 2018 05 9;31(3):393-403. Epub 2017 Dec 9.

Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Aichi, Japan.

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http://dx.doi.org/10.1111/pcmr.12673DOI Listing
May 2018

Characterization of melanosomes and melanin in Japanese patients with Hermansky-Pudlak syndrome types 1, 4, 6, and 9.

Pigment Cell Melanoma Res 2018 03 2;31(2):267-276. Epub 2017 Nov 2.

Department of Dermatology, Faculty of Medicine, Yamagata University, Yamagata, Japan.

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http://dx.doi.org/10.1111/pcmr.12662DOI Listing
March 2018

Decreased benzothiazole-type pheomelanin in regrown brown hair in alopecia areata.

Eur J Dermatol 2018 02;28(1):130-131

Department of Dermatology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan.

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http://dx.doi.org/10.1684/ejd.2017.3194DOI Listing
February 2018

Nevus depigmentosus with yellow hair colour due to an excess amount of benzothiazine-type pheomelanin.

Eur J Dermatol 2018 02;28(1):126-128

Department of Dermatology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan.

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http://dx.doi.org/10.1684/ejd.2017.3193DOI Listing
February 2018

Biochemical Mechanism of Rhododendrol-Induced Leukoderma.

Int J Mol Sci 2018 Feb 12;19(2). Epub 2018 Feb 12.

Department of Chemistry, Fujita Health University School of Health Sciences, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi 470-1192, Japan.

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http://dx.doi.org/10.3390/ijms19020552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855774PMC
February 2018

Melanic variation underlies aposematic color variation in two hymenopteran mimicry systems.

PLoS One 2017 28;12(7):e0182135. Epub 2017 Jul 28.

Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Aichi, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0182135PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533327PMC
October 2017

CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation.

Proc Natl Acad Sci U S A 2017 09 6;114(38):E8035-E8044. Epub 2017 Sep 6.

The Lautenberg Center for Immunology and Cancer Research, Institute for Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel

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http://www.pnas.org/lookup/doi/10.1073/pnas.1702763114
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http://dx.doi.org/10.1073/pnas.1702763114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617257PMC
September 2017

Pheomelanogenesis is promoted at a weakly acidic pH.

Pigment Cell Melanoma Res 2017 05 22;30(3):372-377. Epub 2017 Apr 22.

Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Aichi, Japan.

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http://dx.doi.org/10.1111/pcmr.12587DOI Listing
May 2017

Tyrosinase-Catalyzed Oxidation of the Leukoderma-Inducing Agent Raspberry Ketone Produces (E)-4-(3-Oxo-1-butenyl)-1,2-benzoquinone: Implications for Melanocyte Toxicity.

Chem Res Toxicol 2017 03 6;30(3):859-868. Epub 2017 Mar 6.

Department of Chemistry, Fujita Health University School of Health Sciences , Toyoake, Aichi 470-1192, Japan.

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http://dx.doi.org/10.1021/acs.chemrestox.7b00006DOI Listing
March 2017

MC1R variants affect the expression of melanocortin and melanogenic genes and the association between melanocortin genes and coloration.

Mol Ecol 2017 Jan 14;26(1):259-276. Epub 2016 Oct 14.

Department of Ecology and Evolution, University of Lausanne, Biophore Building, CH-1015, Lausanne, Switzerland.

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http://doi.wiley.com/10.1111/mec.13861
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http://dx.doi.org/10.1111/mec.13861DOI Listing
January 2017

The potent pro-oxidant activity of rhododendrol-eumelanin induces cysteine depletion in B16 melanoma cells.

Pigment Cell Melanoma Res 2017 01;30(1):63-67

Department of Dermatology, Sapporo Medical University School of Medicine, Sapporo, Japan.

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http://dx.doi.org/10.1111/pcmr.12556DOI Listing
January 2017

Scalp nevus depigmentosus with dermoscopy-detectable diverse hair colour.

Eur J Dermatol 2016 Dec;26(6):622-623

Department of Dermatology, Kindai University Faculty of Medicine, Osaka-Sayama.

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http://dx.doi.org/10.1684/ejd.2016.2859DOI Listing
December 2016

Aerobic photoreactivity of synthetic eumelanins and pheomelanins: generation of singlet oxygen and superoxide anion.

Pigment Cell Melanoma Res 2016 11 23;29(6):669-678. Epub 2016 Sep 23.

Department of Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.

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http://dx.doi.org/10.1111/pcmr.12514DOI Listing
November 2016

Elemental characterisation of melanin in feathers via synchrotron X-ray imaging and absorption spectroscopy.

Sci Rep 2016 Sep 23;6:34002. Epub 2016 Sep 23.

University of Manchester, School of Earth and Environmental Sciences, Williamson Research Centre for Molecular Environmental Science, M13 9PL, UK.

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http://dx.doi.org/10.1038/srep34002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034265PMC
September 2016

Quantifying variation in human scalp hair fiber shape and pigmentation.

Am J Phys Anthropol 2016 Jun 9;160(2):341-52. Epub 2016 Mar 9.

Department of Archaeology and Anthropology, PAVE Research Group, University of Cambridge, UK.

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http://dx.doi.org/10.1002/ajpa.22971DOI Listing
June 2016

Dominant Red Coat Color in Holstein Cattle Is Associated with a Missense Mutation in the Coatomer Protein Complex, Subunit Alpha (COPA) Gene.

PLoS One 2015 4;10(6):e0128969. Epub 2015 Jun 4.

Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden; Science for Life Laboratory, Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0128969PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456281PMC
May 2016

Roles of reactive oxygen species in UVA-induced oxidation of 5,6-dihydroxyindole-2-carboxylic acid-melanin as studied by differential spectrophotometric method.

Pigment Cell Melanoma Res 2016 May;29(3):340-51

Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Aichi, Japan.

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http://dx.doi.org/10.1111/pcmr.12469DOI Listing
May 2016

Circulating melanoma cells as a potential biomarker to detect metastasis and evaluate prognosis.

Australas J Dermatol 2016 May 1;57(2):145-9. Epub 2016 Mar 1.

Department of Dermatology, Sapporo Medical University School of Medicine, Sapporo, Japan.

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http://dx.doi.org/10.1111/ajd.12455DOI Listing
May 2016

Effects of Aloe-emodin and Emodin on Proliferation of the MKN45 Human Gastric Cancer Cell Line.

Asian Pac J Cancer Prev 2015 ;16(9):3887-91

Division of Biochemistry, Fujita Memorial Nanakuri Institute, Fujita Health University; 423, Oodori-cho, Tsu, Mie, Japan E-mail :

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http://dx.doi.org/10.7314/apjcp.2015.16.9.3887DOI Listing
February 2016

The slaty (slt/Dct(slt) ) allele decreases the content of eumelanin, but not pheomelanin in the mouse hair.

Pigment Cell Melanoma Res 2016 Jan 18;29(1):110-2. Epub 2015 Nov 18.

Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Japan.

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http://dx.doi.org/10.1111/pcmr.12427DOI Listing
January 2016

Rhododenol-induced leukoderma in a mouse model mimicking Japanese skin.

J Dermatol Sci 2016 Jan 27;81(1):35-43. Epub 2015 Oct 27.

Department of Dermatology, Yamagata University Faculty of Medicine, Yamagata, Japan.

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http://dx.doi.org/10.1016/j.jdermsci.2015.10.011DOI Listing
January 2016

The Metabolic Fate of ortho-Quinones Derived from Catecholamine Metabolites.

Int J Mol Sci 2016 Jan 27;17(2). Epub 2016 Jan 27.

Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Aichi 470-1192, Japan.

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http://dx.doi.org/10.3390/ijms17020164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783898PMC
January 2016

Norepinephrine and its metabolites are involved in the synthesis of neuromelanin derived from the locus coeruleus.

J Neurochem 2015 Nov 4;135(4):768-76. Epub 2015 Sep 4.

Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Aichi, Japan.

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http://doi.wiley.com/10.1111/jnc.13237
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http://dx.doi.org/10.1111/jnc.13237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014224PMC
November 2015

Effects of rhododendrol and its metabolic products on melanocytic cell growth.

J Dermatol Sci 2015 Nov 26;80(2):142-9. Epub 2015 Jul 26.

Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake 470-1192, Japan.

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http://dx.doi.org/10.1016/j.jdermsci.2015.07.010DOI Listing
November 2015

Chemical analysis of constitutive pigmentation of human epidermis reveals constant eumelanin to pheomelanin ratio.

Pigment Cell Melanoma Res 2015 Nov 22;28(6):707-17. Epub 2015 Sep 22.

L'Oréal Research and Innovation, Aulnay-sous-Bois, France.

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http://dx.doi.org/10.1111/pcmr.12410DOI Listing
November 2015

A convenient screening method to differentiate phenolic skin whitening tyrosinase inhibitors from leukoderma-inducing phenols.

J Dermatol Sci 2015 Oct 19;80(1):18-24. Epub 2015 Jul 19.

Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Aichi 470-1192 Japan.

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http://dx.doi.org/10.1016/j.jdermsci.2015.07.007DOI Listing
October 2015

Insects synthesize pheomelanin.

Pigment Cell Melanoma Res 2015 Sep;28(5):599-602

Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Aichi, Japan.

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http://dx.doi.org/10.1111/pcmr.12397DOI Listing
September 2015

An insect with selective control of egg coloration.

Curr Biol 2015 Aug 23;25(15):2007-11. Epub 2015 Jul 23.

Institut de Recherche en Biologie Végétale, Département de Sciences Biologiques, Université de Montréal, Montréal, QC H1X 2B2, Canada.

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http://dx.doi.org/10.1016/j.cub.2015.06.010DOI Listing
August 2015

Inhibitory effects of low-dose aloe-emodin on the development of colorectal tumors in min mice.

Asian Pac J Cancer Prev 2014 ;15(14):5587-92

Division of Biochemistry, Fujita Memorial Nanakuri Institute, Fujita Health University, Tsu, Japan E-mail :

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http://dx.doi.org/10.7314/apjcp.2014.15.14.5587DOI Listing
June 2015

Effect of the MC1R gene on sexual dimorphism in melanin-based colorations.

Mol Ecol 2015 Jun 14;24(11):2794-808. Epub 2015 May 14.

Department of Ecology and Evolution, University of Lausanne, Biophore Building, CH-1015, Lausanne, Switzerland.

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http://dx.doi.org/10.1111/mec.13193DOI Listing
June 2015

Tyrosinase-catalyzed metabolism of rhododendrol (RD) in B16 melanoma cells: production of RD-pheomelanin and covalent binding with thiol proteins.

Pigment Cell Melanoma Res 2015 May 17;28(3):295-306. Epub 2015 Mar 17.

Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Aichi, Japan.

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http://dx.doi.org/10.1111/pcmr.12363DOI Listing
May 2015

Effect of infrared radiation A on photoaged hairless mice harboring eumelanin and pheomelanin in the epidermis.

J Dermatol 2015 Apr 14;42(4):382-90. Epub 2015 Feb 14.

Department of Dermatology, Nippon Medical School, Tokyo, Japan.

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http://dx.doi.org/10.1111/1346-8138.12790DOI Listing
April 2015

Photochemistry. Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure.

Science 2015 Feb;347(6224):842-7

Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA. Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1126/science.1256022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432913PMC
February 2015

Low-quality birds do not display high-quality signals: The cysteine-pheomelanin mechanism of honesty.

Evolution 2015 Jan 4;69(1):26-38. Epub 2014 Dec 4.

Departamento de Ecología Evolutiva, Estación Biológica de Doñana - CSIC, c/ Américo Vespucio s/n, 41092, Sevilla, Spain.

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http://dx.doi.org/10.1111/evo.12549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312981PMC
January 2015

Human tyrosinase is able to oxidize both enantiomers of rhododendrol.

Pigment Cell Melanoma Res 2014 Nov 3;27(6):1149-53. Epub 2014 Sep 3.

Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Aichi, Japan.

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http://dx.doi.org/10.1111/pcmr.12300DOI Listing
November 2014

Black bib size is associated with feather content of pheomelanin in male house sparrows.

Pigment Cell Melanoma Res 2014 Nov 30;27(6):1159-61. Epub 2014 Sep 30.

Departamento de Ecología Evolutiva, Estación Biológica de Doñana - CSIC, Sevilla, Spain.

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http://dx.doi.org/10.1111/pcmr.12313DOI Listing
November 2014

Tyrosinase-catalyzed oxidation of rhododendrol produces 2-methylchromane-6,7-dione, the putative ultimate toxic metabolite: implications for melanocyte toxicity.

Pigment Cell Melanoma Res 2014 Sep 27;27(5):744-53. Epub 2014 Jun 27.

Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Aichi, Japan.

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http://dx.doi.org/10.1111/pcmr.12275DOI Listing
September 2014

Degree of polymerization of 5,6-dihydroxyindole-derived eumelanin from chemical degradation study.

Pigment Cell Melanoma Res 2014 Jul 12;27(4):664-7. Epub 2014 May 12.

Research Institute for Science and Engineering, Waseda University, Tokyo, Japan.

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http://dx.doi.org/10.1111/pcmr.12254DOI Listing
July 2014

Reduction of the nitro group to amine by hydroiodic acid to synthesize o-aminophenol derivatives as putative degradative markers of neuromelanin.

Molecules 2014 Jun 16;19(6):8039-50. Epub 2014 Jun 16.

Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Aichi 470-1192, Japan.

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http://dx.doi.org/10.3390/molecules19068039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270749PMC
June 2014

Buthionine sulfoximine diverts the melanogenesis pathway toward the production of more soluble and degradable pigments.

Bioorg Med Chem Lett 2014 May 21;24(9):2150-4. Epub 2014 Mar 21.

Departamento de Bioquímica y Biología Molecular B e Inmunología, Facultad de Medicina, Universidad de Murcia, 30100 Murcia, Spain.

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http://dx.doi.org/10.1016/j.bmcl.2014.03.031DOI Listing
May 2014

Variants in melanogenesis-related genes associate with skin cancer risk among Japanese populations.

J Dermatol 2014 Apr 12;41(4):296-302. Epub 2014 Mar 12.

Department of Dermatology, Yamagata University Faculty of Medicine, Yamagata, Japan.

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http://dx.doi.org/10.1111/1346-8138.12432DOI Listing
April 2014

TLR4 and NLRP3 inflammasome activation in monocytes by N-propionyl cysteaminylphenol-maleimide-dextran (NPCMD).

J Dermatol Sci 2014 Mar 14;73(3):209-15. Epub 2013 Nov 14.

Faculty of Health and Welfare, Kawasaki University of Medical Welfare, Kurashiki, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jdermsci.2013.11.006DOI Listing
March 2014

The mouse brown (b/Tyrp1(b) ) allele does not affect pheomelanin synthesis in mice.

Zoolog Sci 2014 Feb;31(2):53-63

1 Fukushima Project Headquarters, National Institute of Radiological Sciences, Chiba 263-8555, Japan.

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http://dx.doi.org/10.2108/zsj.31.53DOI Listing
February 2014

Neutral pH and copper ions promote eumelanogenesis after the dopachrome stage.

Pigment Cell Melanoma Res 2013 Nov 5;26(6):817-25. Epub 2013 Aug 5.

Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Aichi, Japan.

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http://dx.doi.org/10.1111/pcmr.12137DOI Listing
November 2013

Raman spectroscopy as a non-invasive technique for the quantification of melanins in feathers and hairs.

Pigment Cell Melanoma Res 2013 Nov 12;26(6):917-23. Epub 2013 Aug 12.

Laboratoire d' Ecologie, Systématique et Evolution, CNRS UMR 8079, Université Paris-Sud 11, Orsay, France.

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http://dx.doi.org/10.1111/pcmr.12140DOI Listing
November 2013

The mouse ruby-eye 2(d) (ru2(d) /Hps5(ru2-d) ) allele inhibits eumelanin but not pheomelanin synthesis.

Pigment Cell Melanoma Res 2013 Sep 3;26(5):723-6. Epub 2013 Jun 3.

Fukushima Restoration Support Headquarters, National Institute of Radiological Sciences, Chiba, Japan.

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http://dx.doi.org/10.1111/pcmr.12118DOI Listing
September 2013

Melanins and melanogenesis: methods, standards, protocols.

Pigment Cell Melanoma Res 2013 Sep 21;26(5):616-33. Epub 2013 Jun 21.

Department of Chemical Sciences, University of Naples Federico II, Naples, Italy.

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http://dx.doi.org/10.1111/pcmr.12121DOI Listing
September 2013

Vibrational characterization of pheomelanin and trichochrome F by Raman spectroscopy.

Spectrochim Acta A Mol Biomol Spectrosc 2013 Jun 13;110:55-9. Epub 2013 Mar 13.

Laboratoire d'Ecologie, Systématique et Evolution, CNRS UMR 8079, Université Paris-Sud 11, Bâtiment 362, F-91405 Orsay Cedex, France.

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http://dx.doi.org/10.1016/j.saa.2013.03.027DOI Listing
June 2013

Photoaging of human retinal pigment epithelium is accompanied by oxidative modifications of its eumelanin.

Pigment Cell Melanoma Res 2013 May 27;26(3):357-66. Epub 2013 Mar 27.

Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Japan.

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http://dx.doi.org/10.1111/pcmr.12078DOI Listing
May 2013

High-performance liquid chromatography estimation of cross-linking of dihydroxyindole moiety in eumelanin.

Anal Biochem 2013 Mar 19;434(2):221-5. Epub 2012 Dec 19.

Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Aichi 470-1192, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S000326971200620
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http://dx.doi.org/10.1016/j.ab.2012.12.005DOI Listing
March 2013

A new mutation of mouse ruby-eye 2, ru2(d)/Hps5(ru2-d) inhibits eumelanin synthesis but stimulates pheomelanin synthesis in melanocytes.

Zoolog Sci 2012 Oct;29(10):652-61

Radiation Risk Reduction Research Program, National Institute of Radiological Sciences, Chiba 263-8555, Japan.

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http://dx.doi.org/10.2108/zsj.29.652DOI Listing
October 2012

Pigment-independent cAMP-mediated epidermal thickening protects against cutaneous UV injury by keratinocyte proliferation.

Exp Dermatol 2012 Oct;21(10):771-7

Department of Pediatrics and the Graduate Center for Toxicology, Markey Cancer Center, University of Kentucky College of Medicine, Lexington, KY 40536-0096, USA.

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http://dx.doi.org/10.1111/exd.12012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481176PMC
October 2012