Kazuhiro Aoki

Kazuhiro Aoki

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Kazuhiro Aoki

Publications by authors named "Kazuhiro Aoki"

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Bif-1/Endophilin B1/SH3GLB1 regulates bone homeostasis.

J Cell Biochem 2019 Nov 26;120(11):18793-18804. Epub 2019 Jun 26.

Division of Molecular Signaling and Biochemistry, Department of Health Improvement, Kyushu Dental University, Kitakyushu, Japan.

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http://dx.doi.org/10.1002/jcb.29193DOI Listing
November 2019

Sulfated Lewis A trisaccharide on oviduct membrane glycoproteins binds bovine sperm and lengthens sperm lifespan.

J Biol Chem 2019 Sep 23;294(36):13445-13463. Epub 2019 Jul 23.

Department of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801

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http://dx.doi.org/10.1074/jbc.RA119.007695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737213PMC
September 2019

Rats deficient in α-galactosidase A develop ocular manifestations of Fabry disease.

Sci Rep 2019 Jun 28;9(1):9392. Epub 2019 Jun 28.

Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA.

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http://dx.doi.org/10.1038/s41598-019-45837-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599056PMC
June 2019

Single-cell quantification of the concentrations and dissociation constants of endogenous proteins.

J Biol Chem 2019 04 9;294(15):6062-6072. Epub 2019 Feb 9.

the Division of Quantitative Biology, National Institute for Basic Biology, National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji-cho, Okazaki, Aichi 444-8787, Japan,

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http://dx.doi.org/10.1074/jbc.RA119.007685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463716PMC
April 2019

The induction of RANKL molecule clustering could stimulate early osteoblast differentiation.

Biochem Biophys Res Commun 2019 02 26;509(2):435-440. Epub 2018 Dec 26.

Department of Basic Oral Health Engineering, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2018.12.093DOI Listing
February 2019

Cell-to-Cell Heterogeneity in p38-Mediated Cross-Inhibition of JNK Causes Stochastic Cell Death.

Cell Rep 2018 09;24(10):2658-2668

Quantitative Biology Research Group, Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji-cho, Okazaki, Aichi 444-8787, Japan; Division of Quantitative Biology, National Institute for Basic Biology, National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji-cho, Okazaki, Aichi 444-8787, Japan; Department of Basic Biology, School of Life Science, SOKENDAI (The Graduate University for Advanced Studies), 5-1 Higashiyama, Myodaiji-cho, Okazaki, Aichi 444-8787, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.08.020DOI Listing
September 2018

Coupling of bone resorption and formation by RANKL reverse signalling.

Nature 2018 09 5;561(7722):195-200. Epub 2018 Sep 5.

Department of Pharmacy, the University of Tokyo Hospital, Faculty of Medicine, the University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1038/s41586-018-0482-7DOI Listing
September 2018

Bacterial Inhibition and Osteoblast Adhesion on Ti Alloy Surfaces Modified by Poly(PEGMA- r-Phosmer) Coating.

ACS Appl Mater Interfaces 2018 Jul 5;10(28):23674-23681. Epub 2018 Jul 5.

Department of Chemical Engineering, Graduate School of Engineering , Kyushu University , 744 Motooka , Nishi-ku, Fukuoka 819-0395 , Japan.

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http://pubs.acs.org/doi/10.1021/acsami.8b07757
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http://dx.doi.org/10.1021/acsami.8b07757DOI Listing
July 2018

Composite regulation of ERK activity dynamics underlying tumour-specific traits in the intestine.

Nat Commun 2018 06 5;9(1):2174. Epub 2018 Jun 5.

Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University, Kyoto, 606-8501, Japan.

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http://dx.doi.org/10.1038/s41467-018-04527-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988836PMC
June 2018

Low-level ultrahigh-frequency and ultrashort-pulse blue laser irradiation enhances osteoblast extracellular calcification by upregulating proliferation and differentiation via transient receptor potential vanilloid 1.

Lasers Surg Med 2018 04 7;50(4):340-352. Epub 2017 Dec 7.

Department of Periodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.

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http://dx.doi.org/10.1002/lsm.22775DOI Listing
April 2018

Glucuronylated core 1 glycans are required for precise localization of neuromuscular junctions and normal formation of basement membranes on Drosophila muscles.

Dev Biol 2018 04 27;436(2):108-124. Epub 2018 Feb 27.

Laboratory of Cell Biology, Department of Bioinformatics, Graduate School of Engineering, Soka University, 1-236 Tangi-machi, Hachioji, Tokyo 192-8577, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2018.02.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898651PMC
April 2018

Live-cell Imaging with Genetically Encoded Protein Kinase Activity Reporters.

Cell Struct Funct 2018 Apr 17;43(1):61-74. Epub 2018 Mar 17.

Division of Quantitative Biology, Okazaki Institute for Integrative Bioscience, National Institute for Basic Biology, National Institutes of Natural Sciences.

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http://dx.doi.org/10.1247/csf.18003DOI Listing
April 2018

Inverse tissue mechanics of cell monolayer expansion.

PLoS Comput Biol 2018 03 1;14(3):e1006029. Epub 2018 Mar 1.

Graduate School of Informatics, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1371/journal.pcbi.1006029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849322PMC
March 2018

Neuropathic pain in a Fabry disease rat model.

JCI Insight 2018 03 22;3(6). Epub 2018 Mar 22.

Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.

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https://insight.jci.org/articles/view/99171
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http://dx.doi.org/10.1172/jci.insight.99171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926911PMC
March 2018

Slightly increased BMI at young age is a risk factor for future hypertension in Japanese men.

PLoS One 2018 11;13(1):e0191170. Epub 2018 Jan 11.

Department of Cardiology, Juntendo University Graduate School of Medicine, Tokyo, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0191170PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764351PMC
February 2018

Effect of doxycycline-treated hydroxyapatite surface on bone apposition: A histomophometric study in murine maxillae.

Dent Mater J 2018 Jan 23;37(1):130-138. Epub 2017 Nov 23.

Department of Oral Implantology and Regenerative Dental Medicine, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University.

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http://dx.doi.org/10.4012/dmj.2017-007DOI Listing
January 2018

Occlusal disharmony-induced stress causes osteopenia of the lumbar vertebrae and long bones in mice.

Sci Rep 2018 01 9;8(1):173. Epub 2018 Jan 9.

Department of Orthodontic Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549, Japan.

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http://dx.doi.org/10.1038/s41598-017-18037-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760568PMC
January 2018

Spatio-temporal variations in bloom of the red-tide dinoflagellate Karenia mikimotoi in Imari Bay, Japan, in 2014: Factors controlling horizontal and vertical distribution.

Mar Pollut Bull 2017 Nov 13;124(1):130-138. Epub 2017 Jul 13.

Saga Prefectural Genkai Fisheries Research and Development Center, 6-4948-9 Tobou, Karatsu, Saga 847-0122, Japan.

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http://dx.doi.org/10.1016/j.marpolbul.2017.07.019DOI Listing
November 2017

Efficient synthesis of phycocyanobilin in mammalian cells for optogenetic control of cell signaling.

Proc Natl Acad Sci U S A 2017 11 24;114(45):11962-11967. Epub 2017 Oct 24.

Okazaki Institute for Integrative Bioscience, National Institutes of Natural Sciences, Okazaki, Aichi 444-8787, Japan;

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http://dx.doi.org/10.1073/pnas.1707190114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5692546PMC
November 2017

Propagating Wave of ERK Activation Orients Collective Cell Migration.

Dev Cell 2017 11;43(3):305-317.e5

Department of Pathology and Biology of Diseases, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan; Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1016/j.devcel.2017.10.016DOI Listing
November 2017

The intra-articular injection of RANKL-binding peptides inhibits cartilage degeneration in a murine model of osteoarthritis.

J Pharmacol Sci 2017 Jun 13;134(2):124-130. Epub 2017 Jun 13.

Department of Basic Oral Health Engineering, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8549, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jphs.2017.05.008DOI Listing
June 2017

Ligature induced peri-implantitis: tissue destruction and inflammatory progression in a murine model.

Clin Oral Implants Res 2017 Feb 22;28(2):129-136. Epub 2016 Jan 22.

Department of Oral Implantology and Regenerative Dental Medicine, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

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http://dx.doi.org/10.1111/clr.12770DOI Listing
February 2017

A threshold of mechanical strain intensity for the direct activation of osteoblast function exists in a murine maxilla loading model.

Biomech Model Mechanobiol 2016 10 17;15(5):1091-100. Epub 2015 Nov 17.

Department of Masticatory Function Rehabilitation (Removable Partial Prosthodontics), Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549, Japan.

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http://dx.doi.org/10.1007/s10237-015-0746-1DOI Listing
October 2016

Mass Spectrometric Quantification of N-Linked Glycans by Reference to Exogenous Standards.

J Proteome Res 2016 09 5;15(9):2969-80. Epub 2016 Aug 5.

National Institute for Bioprocessing Research and Training (NIBRT) , Dublin, Ireland.

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http://dx.doi.org/10.1021/acs.jproteome.6b00132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501980PMC
September 2016

Decontamination of Anodized Implant Surface With Different Modalities for Peri-Implantitis Treatment: Lasers and Mechanical Debridement With Citric Acid.

J Periodontol 2016 Aug 11;87(8):953-61. Epub 2016 Mar 11.

Oral Implantology and Regenerative Dental Medicine, Department of Masticatory Function Rehabilitation, Graduate School of Medical Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

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http://doi.wiley.com/10.1902/jop.2016.150615
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http://dx.doi.org/10.1902/jop.2016.150615DOI Listing
August 2016

Peptide drugs accelerate BMP-2-induced calvarial bone regeneration and stimulate osteoblast differentiation through mTORC1 signaling.

Bioessays 2016 08 27;38(8):717-25. Epub 2016 Jun 27.

Department of Bio-Matrix (Pharmacology), Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

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http://dx.doi.org/10.1002/bies.201600104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094554PMC
August 2016

Peptide-induced de novo bone formation after tooth extraction prevents alveolar bone loss in a murine tooth extraction model.

Eur J Pharmacol 2016 Jul 23;782:89-97. Epub 2016 Apr 23.

Removable Partial Prosthodontics, Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8549, Japan.

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http://dx.doi.org/10.1016/j.ejphar.2016.04.049DOI Listing
July 2016

Multiplexed Fluorescence Imaging of ERK and Akt Activities and Cell-cycle Progression.

Cell Struct Funct 2016 Jul 28;41(2):81-92. Epub 2016 May 28.

Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University.

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http://dx.doi.org/10.1247/csf.16007DOI Listing
July 2016

Visualization of Neuregulin 1 ectodomain shedding reveals its local processing in vitro and in vivo.

Sci Rep 2016 07 1;6:28873. Epub 2016 Jul 1.

Department of Growth Regulation, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1038/srep28873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929465PMC
July 2016

Synaptic roles for phosphomannomutase type 2 in a new Drosophila congenital disorder of glycosylation disease model.

Dis Model Mech 2016 05 3;9(5):513-27. Epub 2016 Mar 3.

Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA Kennedy Center for Research on Human Development, Vanderbilt University, Nashville, TN 37235, USA Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37235, USA

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http://dx.doi.org/10.1242/dmm.022939DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892659PMC
May 2016

Quantification of dissociation constant in living cells by fluorescence cross-correlation spectroscopy.

Authors:
Kazuhiro Aoki

Nihon Yakurigaku Zasshi 2016 02;147(2):74-9

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http://dx.doi.org/10.1254/fpj.147.74DOI Listing
February 2016

Distinct predictive performance of Rac1 and Cdc42 in cell migration.

Sci Rep 2015 Dec 4;5:17527. Epub 2015 Dec 4.

Graduate School of Informatics, Kyoto University, Sakyo, Kyoto, Japan.

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http://dx.doi.org/10.1038/srep17527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669460PMC
December 2015

Chattonella (Raphidophyceae) bloom spatio-temporal variations in Tachibana Bay and the southern area of Ariake Sea, Japan: Interregional displacement patterns with Skeletonema (Bacillariophyceae).

Mar Pollut Bull 2015 Oct 30;99(1-2):54-60. Epub 2015 Jul 30.

Fisheries Department, Nagasaki Prefectural Government, 2-13 Edomachi, Nagasaki, Nagasaki 850-8570, Japan.

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http://dx.doi.org/10.1016/j.marpolbul.2015.07.063DOI Listing
October 2015

Quantitative analysis of recombination between YFP and CFP genes of FRET biosensors introduced by lentiviral or retroviral gene transfer.

Sci Rep 2015 Aug 20;5:13283. Epub 2015 Aug 20.

Imaging Platform for Spatio-Temporal Information, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1038/srep13283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542544PMC
August 2015

Characterization of pulp and follicle stem cells from impacted supernumerary maxillary incisors.

Pediatr Dent 2014 May-Jun;36(3):79-84

Pediatric Dentistry, Department of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

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July 2015

Phytic acid: an alternative root canal chelating agent.

J Endod 2015 Feb 20;41(2):242-7. Epub 2014 Nov 20.

Cariology and Operative Dentistry, Department of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan; Global Center of Excellence (GCOE) Program, International Research Center for Molecular Science in Tooth and Bone Diseases, Tokyo Medical and Dental University, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.joen.2014.09.029DOI Listing
February 2015

Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin.

Elife 2015 Feb 10;4:e05178. Epub 2015 Feb 10.

Department of Pathology and Biology of Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.7554/eLife.05178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337632PMC
February 2015

TGF-β in dentin matrix extract induces osteoclastogenesis in vitro.

Odontology 2015 Jan 24;103(1):9-18. Epub 2013 Dec 24.

Department of Pediatric Dentistry, Faculty of Dentistry, Chulalongkorn University, 34, Henri-Dunant Road, Pathumwan, Bangkok, 10330, Thailand,

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http://dx.doi.org/10.1007/s10266-013-0140-3DOI Listing
January 2015

Qrator: a web-based curation tool for glycan structures.

Glycobiology 2015 Jan 27;25(1):66-73. Epub 2014 Aug 27.

Complex Carbohydrate Research Center, University of Georgia, Athens, GA 30602-7404, USA.

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http://dx.doi.org/10.1093/glycob/cwu090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245907PMC
January 2015

Glycomic analysis of membrane glycoproteins with bisecting glycosylation from ovarian cancer tissues reveals novel structures and functions.

J Proteome Res 2015 Jan 9;14(1):434-46. Epub 2014 Dec 9.

Complex Carbohydrate Research Center and Department of Biochemistry and Molecular Biology, University of Georgia , 315 Riverbend Road, Athens, Georgia 30602, United States.

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http://dx.doi.org/10.1021/pr501174pDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286206PMC
January 2015

The novel IκB kinase β inhibitor IMD-0560 prevents bone invasion by oral squamous cell carcinoma.

Oncotarget 2014 Dec;5(23):12317-30

Division of Molecular Signaling and Biochemistry, Department of Health Promotion, Kyushu Dental University, Manazuru, Kokurakita-ku, Kitakyushu, Fukuoka, Japan. Center for Oral Biological Research, Kyushu Dental University, Manazuru, Kokurakita-ku, Kitakyushu, Fukuoka, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322973PMC
http://dx.doi.org/10.18632/oncotarget.2640DOI Listing
December 2014

NF-κB RELA-deficient bone marrow macrophages fail to support bone formation and to maintain the hematopoietic niche after lethal irradiation and stem cell transplantation.

Int Immunol 2014 Nov 7;26(11):607-18. Epub 2014 Jun 7.

Technology and Development Team for BioSignal Program, RIKEN BioResource Center, RIKEN Institute, Tsukuba 305-074, Japan.

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http://dx.doi.org/10.1093/intimm/dxu062DOI Listing
November 2014

Improved in-gel reductive β-elimination for comprehensive O-linked and sulfo-glycomics by mass spectrometry.

J Vis Exp 2014 Nov 20(93):e51840. Epub 2014 Nov 20.

Complex Carbohydrate Research Center, University of Georgia;

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http://dx.doi.org/10.3791/51840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354198PMC
November 2014

Development of a FRET biosensor with high specificity for Akt.

Cell Struct Funct 2014 9;39(1):9-20. Epub 2013 Nov 9.

Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University.

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http://dx.doi.org/10.1247/csf.13018DOI Listing
October 2014

Gelatin hydrogel as a carrier of recombinant human fibroblast growth factor-2 during rat mandibular distraction.

J Oral Maxillofac Surg 2014 Oct 31;72(10):2015-31. Epub 2014 Mar 31.

Professor, Division of Oral and Maxillofacial Surgery, Department of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S02782391140032
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http://dx.doi.org/10.1016/j.joms.2014.03.014DOI Listing
October 2014

Quantitative in vivo fluorescence cross-correlation analyses highlight the importance of competitive effects in the regulation of protein-protein interactions.

Mol Cell Biol 2014 Sep 23;34(17):3272-90. Epub 2014 Jun 23.

Imaging Platform for Spatio-Temporal Information, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan

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http://mcb.asm.org/content/34/17/3272.full.pdf
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http://mcb.asm.org/cgi/doi/10.1128/MCB.00087-14
Publisher Site
http://dx.doi.org/10.1128/MCB.00087-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135555PMC
September 2014

Inhibition of BMP2-induced bone formation by the p65 subunit of NF-κB via an interaction with Smad4.

Mol Endocrinol 2014 Sep 16;28(9):1460-70. Epub 2014 Jul 16.

Department of Health Improvement (S.H.-T., G.S., C.N., S.K., H.T., E.J.) and Department of Oral Function (S.H.-T., T.M., C.K.), Kyushu Dental University, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu, Fukuoka 803-8580, Japan; Department of Physiological Science and Molecular Biology (H.F.), Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka 814-0193, Japan; Division of Pathophysiology (T.K., S.O., M.S.), Research Center for Genomic Medicine, Saitama Medical University, 1397-1 Yamane, Hidaka-shi, Saitama 350-1241, Japan; Section of Pharmacology (K.N., K.A., K.O.), Department of Bio-Matrix, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8549, Japan; Technology and Development Team for BioSignal Program (T.D.), Subteam for BioSignal Integration, RIKEN BioResource Center, Tsukuba-shi, Ibaraki 305-0074, Japan; Laboratory of Molecular and Cellular Biochemistry (M.H.), Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan; and Center for Oral Biological Research (C.K., E.J.), Kyushu Dental University, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu, Fukuoka 803-8580, Japan.

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https://academic.oup.com/mend/article-lookup/doi/10.1210/me.
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http://dx.doi.org/10.1210/me.2014-1094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414795PMC
September 2014

Fluorescence resonance energy transfer based quantitative analysis of feedforward and feedback loops in epidermal growth factor receptor signaling and the sensitivity to molecular targeting drugs.

FEBS J 2014 Jul 9;281(14):3177-92. Epub 2014 Jun 9.

Department of Pathology and Biology of Diseases, Graduate School of Medicine, Kyoto University, Japan.

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http://dx.doi.org/10.1111/febs.12852DOI Listing
July 2014

Cardiorespiratory fitness and the incidence of type 2 diabetes: a cohort study of Japanese male athletes.

BMC Public Health 2014 May 23;14:493. Epub 2014 May 23.

School of Health and Sports Science, Juntendo University, 1-1 Hiraga-gakuenndai, Inzai, Chiba 270-1695, Japan.

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http://dx.doi.org/10.1186/1471-2458-14-493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038597PMC
May 2014

Variability of factors driving spatial and temporal dispersion in river plume and Chattonella antiqua bloom in the Yatsushiro Sea, Japan.

Mar Pollut Bull 2014 Apr 24;81(1):131-9. Epub 2014 Feb 24.

Kagoshima Prefectural Fisheries Technology and Development Center, 160-10 Takadaue, Iwamotoaza, Ibusuki, Kagoshima 891-0315, Japan.

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http://dx.doi.org/10.1016/j.marpolbul.2014.02.005DOI Listing
April 2014

Discrimination between adenocarcinoma and normal pancreatic ductal fluid by proteomic and glycomic analysis.

J Proteome Res 2014 Feb 12;13(2):395-407. Epub 2013 Dec 12.

Complex Carbohydrate Research Center, ‡Chemistry Department, and §Department of Biochemistry and Molecular Biology, University of Georgia , Athens, Georgia 30602, United States.

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http://dx.doi.org/10.1021/pr400422gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946306PMC
February 2014

p130Cas, Crk-associated substrate, plays important roles in osteoclastic bone resorption.

J Bone Miner Res 2013 Dec;28(12):2449-62

Division of Molecular Signaling and Biochemistry, Department of Health Improvement, Kyushu Dental University, Fukuoka, Japan; Division of Developmental Stomatognathic Function Science, Department of Health Improvement, Kyushu Dental University, Fukuoka, Japan.

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http://doi.wiley.com/10.1002/jbmr.1936
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http://dx.doi.org/10.1002/jbmr.1936DOI Listing
December 2013

Analyses of associations between reactive oxygen metabolites and antioxidant capacity and related factors among healthy adolescents.

Curr Aging Sci 2013 Dec;6(3):258-65

Faculty of Education and Welfare Science, Oita University, Oita city, Oita, 870-1192, Japan.

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December 2013

Occurrence and potential activity of denitrifiers and methanogens in groundwater at 140 m depth in Pliocene diatomaceous mudstone of northern Japan.

FEMS Microbiol Ecol 2013 Dec 30;86(3):532-43. Epub 2013 Jul 30.

Department of Geosciences, Faculty of Science, Shizuoka University, Shizuoka, Japan; Department of Biological Sciences, Faculty of Science and Engineering, Chuo University, Tokyo, Japan.

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http://dx.doi.org/10.1111/1574-6941.12179DOI Listing
December 2013

Selective exo-enzymatic labeling of N-glycans on the surface of living cells by recombinant ST6Gal I.

Angew Chem Int Ed Engl 2013 Dec 15;52(49):13012-5. Epub 2013 Oct 15.

Complex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, GA 30602 (USA); Department of Chemistry, University of Georgia (USA).

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http://dx.doi.org/10.1002/anie.201307095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869382PMC
December 2013

Stochastic ERK activation induced by noise and cell-to-cell propagation regulates cell density-dependent proliferation.

Mol Cell 2013 Nov 17;52(4):529-40. Epub 2013 Oct 17.

Imaging Platform for Spatio-Temporal Information, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2013.09.015DOI Listing
November 2013

Regulation of protein glycosylation and sorting by the Golgi matrix proteins GRASP55/65.

Nat Commun 2013 ;4:1659

Department of Molecular, Cellular and Developmental Biology, University of Michigan, 830 North University Avenue, Ann Arbor, Michigan 48109-1048, USA.

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http://dx.doi.org/10.1038/ncomms2669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620728PMC
October 2013

A quantitative model of ERK MAP kinase phosphorylation in crowded media.

Sci Rep 2013 ;3:1541

Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1038/srep01541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607838PMC
September 2013

In-gel β-elimination and aqueous-organic partition for improved O- and sulfoglycomics.

Anal Chem 2013 Sep 27;85(18):8692-9. Epub 2013 Aug 27.

Complex Carbohydrate Research Center, University of Georgia , 315 Riverbend Road, Athens, Georgia 30602, United States.

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http://dx.doi.org/10.1021/ac4015935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004059PMC
September 2013

Wheat gluten hydrolysate affects race performance in the triathlon.

Biomed Rep 2013 Jul 14;1(4):646-650. Epub 2013 May 14.

School of Health and Sports Science, Juntendo University, Inzai, Chiba 270-1695;

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http://dx.doi.org/10.3892/br.2013.105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917000PMC
July 2013

Disruption of NF-κB1 prevents bone loss caused by mechanical unloading.

J Bone Miner Res 2013 Jun;28(6):1457-67

Division of Molecular Signaling and Biochemistry, Department of Health Improvement, Kyushu Dental University, Fukuoka, Japan.

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http://dx.doi.org/10.1002/jbmr.1866DOI Listing
June 2013

Fluorescence resonance energy transfer imaging of cell signaling from in vitro to in vivo: basis of biosensor construction, live imaging, and image processing.

Dev Growth Differ 2013 May 7;55(4):515-22. Epub 2013 Feb 7.

Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University, Sakyo-ku, Kyoto, 606-8501, Japan.

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http://doi.wiley.com/10.1111/dgd.12039
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http://dx.doi.org/10.1111/dgd.12039DOI Listing
May 2013

Effect of yellow-tinted lenses on visual attributes related to sports activities.

J Hum Kinet 2013 Mar 28;36:27-36. Epub 2013 Mar 28.

School of Health and Sports Science, Juntendo University.

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http://dx.doi.org/10.2478/hukin-2013-0003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661891PMC
March 2013

Osteoclast formation and differentiation: an overview.

J Med Dent Sci 2012 Nov 8;59(3):65-74. Epub 2012 Nov 8.

Section of Pharmacology, Department of Bio-Matrix, Graduate School, Tokyo Medical and Dental University, Japan.

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November 2012

Biosynthesis of the major brain gangliosides GD1a and GT1b.

Glycobiology 2012 Oct 26;22(10):1289-301. Epub 2012 Jun 26.

Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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https://academic.oup.com/glycob/article-lookup/doi/10.1093/g
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http://dx.doi.org/10.1093/glycob/cws103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425327PMC
October 2012

Selective inhibition of NF-κB suppresses bone invasion by oral squamous cell carcinoma in vivo.

Int J Cancer 2012 Sep 23;131(5):E625-35. Epub 2012 Feb 23.

Division of Molecular Signaling and Biochemistry, Department of Bioscience, Kyushu Dental College, Kokurakita-ku, Kitakyushu, Fukuoka, Japan.

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http://dx.doi.org/10.1002/ijc.27435DOI Listing
September 2012

Peptide-based delivery to bone.

Adv Drug Deliv Rev 2012 Sep 16;64(12):1220-38. Epub 2012 Jun 16.

Dept. of Hard Tissue Engineering (Pharmacology), Graduate School, Tokyo Medical & Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.addr.2012.05.017DOI Listing
September 2012

CXCL2 synthesized by oral squamous cell carcinoma is involved in cancer-associated bone destruction.

Biochem Biophys Res Commun 2012 Aug 4;424(3):456-61. Epub 2012 Jul 4.

Section of Oral Pathology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X120123
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http://dx.doi.org/10.1016/j.bbrc.2012.06.132DOI Listing
August 2012

Porcine sperm bind to specific 6-sialylated biantennary glycans to form the oviduct reservoir.

Biol Reprod 2012 Jun 27;87(6):147. Epub 2012 Dec 27.

Department of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.

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http://dx.doi.org/10.1095/biolreprod.112.103879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435431PMC
June 2012

FRET imaging and statistical signal processing reveal positive and negative feedback loops regulating the morphology of randomly migrating HT-1080 cells.

J Cell Sci 2012 May 17;125(Pt 10):2381-92. Epub 2012 Feb 17.

Department of Pathology and Biology of Diseases, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan.

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http://dx.doi.org/10.1242/jcs.096859DOI Listing
May 2012

Stable expression of FRET biosensors: a new light in cancer research.

Cancer Sci 2012 Apr 3;103(4):614-9. Epub 2012 Feb 3.

Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2011.02196.xDOI Listing
April 2012

[Computational simulation based on experimentally-determined kinetic parameters in signal transduction].

Authors:
Kazuhiro Aoki

Seikagaku 2012 Apr;84(4):301-5

Graduate School of Biostudies, Kyoto University, JST, PREST, Yoshida-Konoe-cho, Sakyo-ku, Kyoto, 606-8315, Japan.

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April 2012