Kazuharu Kai

Kazuharu Kai

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Kazuharu Kai

Kazuharu Kai

Publications by authors named "Kazuharu Kai"

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Secretory microRNAs as biomarkers of cancer.

Semin Cell Dev Biol 2018 06 19;78:22-36. Epub 2017 Dec 19.

Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, United States; Program in Human and Molecular Genetics, The University of Texas Graduate School of Biomedical Sciences, Houston, TX, 77030, United States. Electronic address:

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http://dx.doi.org/10.1016/j.semcdb.2017.12.011DOI Listing
June 2018

Functional Significance of Aurora Kinases-p53 Protein Family Interactions in Cancer.

Front Oncol 2016 25;6:247. Epub 2016 Nov 25.

Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center , Houston, TX , USA.

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http://dx.doi.org/10.3389/fonc.2016.00247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122578PMC
November 2016

Antitumor Activity of KW-2450 against Triple-Negative Breast Cancer by Inhibiting Aurora A and B Kinases.

Mol Cancer Ther 2015 Dec 6;14(12):2687-99. Epub 2015 Oct 6.

Section of Translational Breast Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674309PMC
December 2015

Clinical characteristics and outcome of bone-only metastasis in inflammatory and noninflammatory breast cancers.

Clin Breast Cancer 2015 Feb 15;15(1):37-42. Epub 2014 Aug 15.

Department of Breast Medical Oncology, The University Texas MD Anderson Cancer Center, Houston, TX; Morgan Welch Inflammatory Breast Cancer Research Program and Clinic, The University Texas MD Anderson Cancer Center, Houston, TX. Electronic address:

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http://dx.doi.org/10.1016/j.clbc.2014.06.007DOI Listing
February 2015

A Brief Review of the Biophysical Hallmarks of Metastatic Cancer Cells.

Cancer Hallm 2013 Aug;1(2-3):59-66

Department of Nanomedicine, The Methodist Hospital Research Institute, Houston, TX 77030, USA ; Department of Cell and Developmental Biology, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10065, USA.

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http://dx.doi.org/10.1166/ch.2013.1010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189832PMC
August 2013

Microfluidics separation reveals the stem-cell-like deformability of tumor-initiating cells.

Proc Natl Acad Sci U S A 2012 Nov 29;109(46):18707-12. Epub 2012 Oct 29.

Department of Nanomedicine and Methodist Cancer Center, Methodist Hospital Research Institute, Houston, TX 77030, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1209893109
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http://dx.doi.org/10.1073/pnas.1209893109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503214PMC
November 2012

Loss of p16 expression is associated with the stem cell characteristics of surface markers and therapeutic resistance in estrogen receptor-negative breast cancer.

Int J Cancer 2012 Jun 24;130(11):2568-79. Epub 2011 Aug 24.

Division of Gene Regulation, Institute for Advanced Medical Research, School of Medicine, Keio University, Tokyo 160-8582, Japan.

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http://doi.wiley.com/10.1002/ijc.26271
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http://dx.doi.org/10.1002/ijc.26271DOI Listing
June 2012

Breast cancer stem cells.

Breast Cancer 2010 Apr 6;17(2):80-5. Epub 2009 Oct 6.

Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine, Keio University, 35 Shinano-machi, Shinjuku-ku, Tokyo 160-8582, Japan.

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http://dx.doi.org/10.1007/s12282-009-0176-yDOI Listing
April 2010

CD44+ slow-cycling tumor cell expansion is triggered by cooperative actions of Wnt and prostaglandin E2 in gastric tumorigenesis.

Cancer Sci 2010 Mar 18;101(3):673-8. Epub 2009 Dec 18.

Division of Gene Regulation, Institute for Advanced Medical Research, School of Medicine, Keio University, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2009.01430.xDOI Listing
March 2010

Maintenance of HCT116 colon cancer cell line conforms to a stochastic model but not a cancer stem cell model.

Cancer Sci 2009 Dec 19;100(12):2275-82. Epub 2009 Aug 19.

Division of Gene Regulation, Institute for Advanced Medical Research, School of Medicine, Keio University, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2009.01318.xDOI Listing
December 2009

Pathological lymph node involvement at surgery is a significant predictive factor of recurrence in locally advanced breast cancer treated with concomitant epirubicin-docetaxel neoadjuvant chemotherapy: a cohort study.

Breast Cancer 2009 27;16(1):42-8. Epub 2008 May 27.

Breast and Endocrine Surgery, Faculty of Medical and Pharmaceutical Science, Kumamoto University, 1-1-1 Honjo, Kumamoto, 860-8556, Japan.

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http://dx.doi.org/10.1007/s12282-008-0055-yDOI Listing
February 2009

Loss of heterozygosity at the ATBF1-A locus located in the 16q22 minimal region in breast cancer.

BMC Cancer 2008 Sep 16;8:262. Epub 2008 Sep 16.

Department of Breast and Endocrine Surgery, Faculty of Medical and Pharmaceutical Science, Kumamoto University, Kumamoto, Japan.

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http://dx.doi.org/10.1186/1471-2407-8-262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2564977PMC
September 2008

Hypoxia-inducible factor 1alpha is closely linked to an aggressive phenotype in breast cancer.

Breast Cancer Res Treat 2008 Aug 6;110(3):465-75. Epub 2007 Sep 6.

Department of Breast & Endocrine Surgery, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University Graduate School of Medical Sciences, 1-1-1 Honjo, Kumamoto 860-8556 Kumamoto, Japan.

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http://dx.doi.org/10.1007/s10549-007-9742-1DOI Listing
August 2008

p53 expression status is a significant molecular marker in predicting the time to endocrine therapy failure in recurrent breast cancer: a cohort study.

Int J Clin Oncol 2006 Dec 25;11(6):426-33. Epub 2006 Dec 25.

Breast and Endocrine Surgery, Faculty of Medical and Pharmaceutical Science, Kumamoto University, 1-1-1 Honjo, Kumamoto 860-8556, Japan.

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http://dx.doi.org/10.1007/s10147-006-0601-6DOI Listing
December 2006

[Significance of local ablation therapy following portal embolization therapy for hepatocellular carcinoma with portal vein tumor thrombus].

Gan To Kagaku Ryoho 2003 Oct;30(11):1702-5

Dept. of Digestive Surgery, Graduate School of Medicine, Kumamoto University.

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October 2003

[Multidisciplinary treatment for hepatocellular carcinoma invading the stomach].

Gan To Kagaku Ryoho 2003 Oct;30(11):1741-4

Dept. of Gastroenterological Surgery, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University.

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October 2003