Publications by authors named "Kazuaki Chayama"

99Publications

Clinical Features and Genomic Characterization of Post-Colonoscopy Colorectal Cancer.

Clin Transl Gastroenterol 2020 Oct;11(10):e00246

Department of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.

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http://dx.doi.org/10.14309/ctg.0000000000000246DOI Listing
October 2020

Association of Body Mass Index with Endothelial Function in Asian Men.

Int J Cardiol 2020 Sep 12. Epub 2020 Sep 12.

Division of Regeneration and Medicine, Medical Center for Translational and Clinical Research, Hiroshima University Hospital, Hiroshima, Japan; Department of Cardiovascular Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2020.09.029DOI Listing
September 2020

Usefulness of peroral cholangioscopy in the differential diagnosis of IgG4-related sclerosing cholangitis and extrahepatic cholangiocarcinoma: a single-center retrospective study.

BMC Gastroenterol 2020 Aug 24;20(1):287. Epub 2020 Aug 24.

Department of Gastroenterology and Metabolism, Graduate School of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.

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http://dx.doi.org/10.1186/s12876-020-01429-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445926PMC
August 2020

A Comparison of Adrenalectomy and Eplerenone on Vascular Function in Patients with Aldosterone-producing Adenoma.

J Clin Endocrinol Metab 2020 Nov;105(11)

Department of Cardiovascular Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.

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http://dx.doi.org/10.1210/clinem/dgaa561DOI Listing
November 2020

Trends in Hepatic Functional Reserve of Patients with Hepatocellular Carcinoma Treated with Tyrosine Kinase Inhibitors.

Oncology 2020 24;98(10):727-733. Epub 2020 Jul 24.

Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan,

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http://dx.doi.org/10.1159/000507815DOI Listing
October 2020

Tumor Fibroblast Growth Factor Receptor 4 Level Predicts the Efficacy of Lenvatinib in Patients With Advanced Hepatocellular Carcinoma.

Clin Transl Gastroenterol 2020 May;11(5):e00179

1Department of Gastroenterology and Metabolism, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan; 2Department of Clinical Oncology, Hiroshima University Hospital, Hiroshima, Japan; 3Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan; 4Laboratory for Cancer Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan; 5Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan; 6Institute of Physical and Chemical Research (RIKEN) Center for Integrative Medical Sciences, Yokohama, Japan.

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http://dx.doi.org/10.14309/ctg.0000000000000179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263646PMC
May 2020

Real-word efficacy of sofosbuvir, velpatasvir plus ribavirin therapy for chronic hepatitis patients who failed to prior DAA therapy with NS5A-P32 deletion mutated HCV infection.

Clin J Gastroenterol 2020 Jul 12. Epub 2020 Jul 12.

Department of Gastroenterology and Metabolism, Graduate School of Biomedical and Health Science, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.

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http://dx.doi.org/10.1007/s12328-020-01182-9DOI Listing
July 2020

[Current status and future prospects of endoscopic treatment for rectal cancer].

Nihon Shokakibyo Gakkai Zasshi 2020;117(7):559-570

Department of Gastroenterology and Metabolism, Hiroshima University Hospital.

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http://dx.doi.org/10.11405/nisshoshi.117.559DOI Listing
September 2020

Hematocrit, hemoglobin and red blood cells are associated with vascular function and vascular structure in men.

Sci Rep 2020 Jul 10;10(1):11467. Epub 2020 Jul 10.

Department of Cardiovascular Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.

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http://dx.doi.org/10.1038/s41598-020-68319-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351756PMC
July 2020

PD1 gene polymorphism is associated with a poor prognosis in hepatocellular carcinoma following liver resection, cohort study.

Int J Surg 2020 Aug 29;80:84-90. Epub 2020 Jun 29.

Department of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan; Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan.

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http://dx.doi.org/10.1016/j.ijsu.2020.05.007DOI Listing
August 2020

Renal metastasis from primary hepatocellular carcinoma: a case report.

Int Cancer Conf J 2020 Jul 25;9(3):141-145. Epub 2020 Mar 25.

Department of Urology, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551 Japan.

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http://dx.doi.org/10.1007/s13691-020-00409-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297933PMC
July 2020

Clinical significance of endoscopic ultrasonography in diagnosing invasion depth of early gastric cancer prior to endoscopic submucosal dissection.

Gastric Cancer 2020 Jun 22. Epub 2020 Jun 22.

Department of Gastroenterology and Metabolism, Hiroshima University Hospital, Kasumi 1-2-3, Minami-ku, Hiroshima-shi, Hiroshima, Japan.

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http://dx.doi.org/10.1007/s10120-020-01100-5DOI Listing
June 2020

Treatment outcomes after splenectomy with gastric devascularization or balloon-occluded retrograde transvenous obliteration for gastric varices: a propensity score-weighted analysis from a single institution.

J Gastroenterol 2020 Sep 12;55(9):877-887. Epub 2020 Jun 12.

Department of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.

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http://dx.doi.org/10.1007/s00535-020-01693-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289714PMC
September 2020

Impact of the introduction of direct-acting anti-viral drugs on hepatocarcinogenesis: a prospective serial follow-up MRI study.

Aliment Pharmacol Ther 2020 07 10;52(2):359-370. Epub 2020 Jun 10.

Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1111/apt.15825DOI Listing
July 2020

Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases.

Nat Genet 2020 07 8;52(7):669-679. Epub 2020 Jun 8.

Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.

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http://dx.doi.org/10.1038/s41588-020-0640-3DOI Listing
July 2020

Clinical Usefulness of Serum Autotaxin for Early Prediction of Relapse in Male Patients with Type 1 Autoimmune Pancreatitis.

Dig Dis Sci 2020 May 20. Epub 2020 May 20.

Department of Gastroenterology and Metabolism, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.

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http://dx.doi.org/10.1007/s10620-020-06338-8DOI Listing
May 2020

Skeletal Muscle Loss during Tyrosine Kinase Inhibitor Treatment for Advanced Hepatocellular Carcinoma Patients.

Liver Cancer 2020 Apr 8;9(2):148-155. Epub 2019 Nov 8.

Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.

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http://dx.doi.org/10.1159/000503829DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206610PMC
April 2020

Modeling-Based Response-Guided Glecaprevir-Pibrentasvir Therapy for Chronic Hepatitis C to Identify Patients for Ultrashort Treatment Duration.

J Infect Dis 2020 Sep;222(7):1165-1169

Department of Gastroenterology and Metabolism, Graduate School of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.

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http://dx.doi.org/10.1093/infdis/jiaa219DOI Listing
September 2020

Characteristics and Early Diagnosis of Gastric Cancer Discovered after Eradication.

Gut Liver 2020 Apr 24. Epub 2020 Apr 24.

Department of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.

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http://dx.doi.org/10.5009/gnl19418DOI Listing
April 2020

Correction to: Genomic landscape of epithelium with low-grade atypia on gastric cancer after Helicobacter pylori eradication therapy.

J Gastroenterol 2020 Jun;55(6):666

Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Science, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.

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http://dx.doi.org/10.1007/s00535-020-01688-6DOI Listing
June 2020

Serum amyloid A is a better predictive biomarker of mucosal healing than C-reactive protein in ulcerative colitis in clinical remission.

BMC Gastroenterol 2020 Apr 3;20(1):85. Epub 2020 Apr 3.

Department of Gastroenterology and Metabolism, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.

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http://dx.doi.org/10.1186/s12876-020-01229-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118889PMC
April 2020

Clinical outcomes of endoscopic resection for superficial non-ampullary duodenal tumors.

Endosc Int Open 2020 Mar 21;8(3):E354-E359. Epub 2020 Feb 21.

Department of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.

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http://dx.doi.org/10.1055/a-0998-3708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035028PMC
March 2020

Genomic Characterization of Non-Invasive Differentiated-Type Gastric Cancer in the Japanese Population.

Cancers (Basel) 2020 Feb 22;12(2). Epub 2020 Feb 22.

Department of Gastroenterology and Metabolism, Institute of Biomedical and Health Science, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan.

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http://dx.doi.org/10.3390/cancers12020510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072322PMC
February 2020

Complete response to pembrolizumab in advanced hepatocellular carcinoma with microsatellite instability.

Clin J Gastroenterol 2020 Oct 4;13(5):867-872. Epub 2020 Feb 4.

Department of Gastroenterology and Metabolism, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minamiku, Hiroshima, 734-8551, Japan.

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http://dx.doi.org/10.1007/s12328-020-01099-3DOI Listing
October 2020

Sinusoidal obstruction syndrome post-treatment with trastuzumab emtansine (T-DM1) in advanced breast cancer.

Int Cancer Conf J 2020 Jan 24;9(1):18-23. Epub 2019 Oct 24.

3Department of Gastroenterology and Metabolism, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551 Japan.

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http://dx.doi.org/10.1007/s13691-019-00392-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942611PMC
January 2020

Predicting atrial fibrillation using a combination of genetic risk score and clinical risk factors.

Heart Rhythm 2020 May 11;17(5 Pt A):699-705. Epub 2020 Jan 11.

Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan.

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http://dx.doi.org/10.1016/j.hrthm.2020.01.006DOI Listing
May 2020

Clinical Utility of Emergency Capsule Endoscopy for Diagnosing the Source and Nature of Ongoing Overt Obscure Gastrointestinal Bleeding.

Gastroenterol Res Pract 2019 1;2019:5496242. Epub 2019 Dec 1.

Department of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.

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http://dx.doi.org/10.1155/2019/5496242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914955PMC
December 2019

Comparative study on the replication of HCV1b genome between wild-type and cell culture-adaptive mutant in regard to sensitivities against anti-HCV drugs.

Microbiol Immunol 2020 Apr 31;64(4):296-303. Epub 2020 Jan 31.

Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1111/1348-0421.12768DOI Listing
April 2020

Pruritus in patients with chronic liver disease and serum autotaxin levels in patients with primary biliary cholangitis.

BMC Gastroenterol 2019 Oct 24;19(1):169. Epub 2019 Oct 24.

Department of Gastroenterology and Metabolism, Graduate School of Biomedical and Health Science, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.

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http://dx.doi.org/10.1186/s12876-019-1092-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813053PMC
October 2019

Long-Term Outcomes after Endoscopic Submucosal Dissection for Ulcerative Colitis-Associated Dysplasia.

Digestion 2019 Oct 10:1-11. Epub 2019 Oct 10.

Department of Gastroenterology and Metabolism, University Hospital, Hiroshima, Japan.

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http://dx.doi.org/10.1159/000503341DOI Listing
October 2019

Can surveillance colonoscopy be discontinued in an elderly population with diminutive polyps?

J Anus Rectum Colon 2019 30;3(3):128-135. Epub 2019 Jul 30.

Department of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.

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http://dx.doi.org/10.23922/jarc.2018-042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774739PMC
July 2019

Exacerbation of Portal Hypertensive Enteropathy after Endoscopic Injection Sclerotherapy for Esophageal Varices.

Digestion 2019 Oct 1:1-9. Epub 2019 Oct 1.

Department of Gastroenterology and Metabolism, Hiroshima University Hospital, Minami-ku, Hiroshima, Japan.

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http://dx.doi.org/10.1159/000503060DOI Listing
October 2019

Efficacy of a self-management program in patients with chronic viral hepatitis in China.

BMC Nurs 2019 18;18:44. Epub 2019 Sep 18.

6Graduate School of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8553 Japan.

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http://dx.doi.org/10.1186/s12912-019-0366-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749624PMC
September 2019

Management of refractory ascites attenuates muscle mass reduction and improves survival in patients with decompensated cirrhosis.

J Gastroenterol 2020 Feb 4;55(2):217-226. Epub 2019 Sep 4.

Department of Gastroenterology and Metabolism, Hiroshima University Hospital, 1-2-3 Kasumi, Minamiku, Hiroshima, 734-8551, Japan.

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http://dx.doi.org/10.1007/s00535-019-01623-4DOI Listing
February 2020

Real-world learning curve analysis of colorectal endoscopic submucosal dissection: a large multicenter study.

Surg Endosc 2020 Aug 3;34(8):3344-3351. Epub 2019 Sep 3.

Department of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.

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http://dx.doi.org/10.1007/s00464-019-07104-2DOI Listing
August 2020

Regression of Idiopathic Thrombocytopenic Purpura in a Patient With Eradication of Hepatitis C Virus by Direct-Acting Antivirals.

Hepatology 2020 01 11;71(1):389-391. Epub 2019 Oct 11.

Department of Gastroenterology and Metabolism, Graduate School of Biomedical and Health Sciences, Hiroshima University, Minami-ku, Hiroshima, Japan.

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http://dx.doi.org/10.1002/hep.30900DOI Listing
January 2020

Alcohol Use Disorders Identification Test-consumption Predicts the Risk of Excessive Alcohol Consumption After Liver Transplantation.

Transplant Proc 2019 Jul - Aug;51(6):1934-1938

Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.

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http://dx.doi.org/10.1016/j.transproceed.2019.02.031DOI Listing
December 2019

Management of HCV patients in cases of direct-acting antiviral failure.

Expert Rev Gastroenterol Hepatol 2019 Sep 8;13(9):839-848. Epub 2019 Aug 8.

Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University , Hiroshima , Japan.

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https://www.tandfonline.com/doi/full/10.1080/17474124.2019.1
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http://dx.doi.org/10.1080/17474124.2019.1651642DOI Listing
September 2019

Association of extremely high levels of high-density lipoprotein cholesterol with endothelial dysfunction in men.

J Clin Lipidol 2019 Jul - Aug;13(4):664-672.e1. Epub 2019 Jun 20.

Division of Regeneration and Medicine, Medical Center for Translational and Clinical Research, Hiroshima University Hospital, Hiroshima, Japan; Department of Cardiovascular Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jacl.2019.06.004DOI Listing
June 2020

Genomic characterization of early-stage esophageal squamous cell carcinoma in a Japanese population.

Oncotarget 2019 Jun 25;10(41):4139-4148. Epub 2019 Jun 25.

Department of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.

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http://dx.doi.org/10.18632/oncotarget.27014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609253PMC
June 2019

Experience with Balloon Dilatation in Crohn's and Non-Crohn's Benign Small-Bowel Strictures: Is There a Difference?

Gastroenterol Res Pract 2019 6;2019:1262595. Epub 2019 May 6.

Department of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.

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http://dx.doi.org/10.1155/2019/1262595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526561PMC
May 2019

Genomic landscape of epithelium with low-grade atypia on gastric cancer after Helicobacter pylori eradiation therapy.

J Gastroenterol 2019 Oct 13;54(10):907-915. Epub 2019 Jun 13.

Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Science, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.

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http://dx.doi.org/10.1007/s00535-019-01596-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759680PMC
October 2019

Hepatitis B virus X protein (HBx) enhances centrosomal P4.1-associated protein (CPAP) expression to promote hepatocarcinogenesis.

J Biomed Sci 2019 Jun 6;26(1):44. Epub 2019 Jun 6.

Department of Biotechnology and Bioindustry Sciences, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, 70101, Taiwan.

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http://dx.doi.org/10.1186/s12929-019-0534-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551916PMC
June 2019

Genomic and Transcriptomic Profiling of Combined Hepatocellular and Intrahepatic Cholangiocarcinoma Reveals Distinct Molecular Subtypes.

Cancer Cell 2019 06 23;35(6):932-947.e8. Epub 2019 May 23.

Biomedical Pioneering Innovation Center (BIOPIC) and Translational Cancer Research Center, School of Life Sciences, First Hospital, Peking University, Beijing 100871, China; Laboratory of Cancer Cell Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.04.007DOI Listing
June 2019

Potential of Helicobacter pylori-uninfected signet ring cell carcinoma to invade the submucosal layer.

J Gastroenterol Hepatol 2019 Nov 30;34(11):1955-1962. Epub 2019 May 30.

Department of Medicine and Molecular Science, Hiroshima University, Hiroshima, Japan.

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http://dx.doi.org/10.1111/jgh.14706DOI Listing
November 2019

Diagnostic Yield of Colon Capsule Endoscopy in Detection of Superficial Colorectal Lesions.

Digestion 2020 27;101(3):262-269. Epub 2019 Mar 27.

Department of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.

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http://dx.doi.org/10.1159/000499332DOI Listing
March 2019