Kausik Chattopadhyay

Kausik Chattopadhyay

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Kausik Chattopadhyay

Kausik Chattopadhyay

Publications by authors named "Kausik Chattopadhyay"

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Revisiting the role of cholesterol in regulating the pore-formation mechanism of cytolysin, a membrane-damaging β-barrel pore-forming toxin.

Biochem J 2018 Oct 9;475(19):3039-3055. Epub 2018 Oct 9.

Centre for Protein Science, Design and Engineering, Department of Biological Sciences, Indian Institute of Science Education and Research Mohali, Sector 81, SAS Nagar, Manauli, Mohali 140306, Punjab, India

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http://dx.doi.org/10.1042/BCJ20180387DOI Listing
October 2018

Vibrio cholerae cytolysin: Multiple facets of the membrane interaction mechanism of a β-barrel pore-forming toxin.

IUBMB Life 2018 04 22;70(4):260-266. Epub 2018 Feb 22.

Centre for Protein Science, Design and Engineering, Department of Biological Sciences, Indian Institute of Science Education and Research Mohali, Manauli, Mohali, Punjab, India.

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http://doi.wiley.com/10.1002/iub.1725
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http://dx.doi.org/10.1002/iub.1725DOI Listing
April 2018

Structural Basis and Functional Implications of the Membrane Pore-Formation Mechanisms of Bacterial Pore-Forming Toxins.

Adv Exp Med Biol 2018;1112:281-291

Centre for Protein Science, Design and Engineering, Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Mohali, Punjab, India.

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http://link.springer.com/10.1007/978-981-13-3065-0_19
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http://dx.doi.org/10.1007/978-981-13-3065-0_19DOI Listing
January 2018

Use of jaggery and honey as adjunctive cytological fixatives to ethanol for oral smears.

J Oral Maxillofac Pathol 2017 May-Aug;21(2):317

Department of Metallurgical Engineering, IIT, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

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http://dx.doi.org/10.4103/jomfp.JOMFP_224_15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596689PMC
September 2017

Disulphide bond restrains the C-terminal region of thermostable direct hemolysin during folding to promote oligomerization.

Biochem J 2017 01 26;474(2):317-331. Epub 2016 Oct 26.

Centre for Protein Science, Design and Engineering, Department of Biological Sciences, Indian Institute of Science Education and Research Mohali, Sector 81, SAS Nagar, Manauli, Mohali, Punjab 140306, India.

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http://biochemj.org/lookup/doi/10.1042/BCJ20160728
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http://dx.doi.org/10.1042/BCJ20160728DOI Listing
January 2017

Revisiting the oligomerization mechanism of Vibrio cholerae cytolysin, a beta-barrel pore-forming toxin.

Biochem Biophys Res Commun 2016 06 2;474(3):421-427. Epub 2016 May 2.

Centre for Protein Science, Design and Engineering, Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Sector 81, SAS Nagar, Manauli, Mohali, 140306 Punjab, India. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X163068
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http://dx.doi.org/10.1016/j.bbrc.2016.05.006DOI Listing
June 2016

Physicochemical constraints of elevated pH affect efficient membrane interaction and arrest an abortive membrane-bound oligomeric intermediate of the beta-barrel pore-forming toxin Vibrio cholerae cytolysin.

Arch Biochem Biophys 2015 Oct 31;583:9-17. Epub 2015 Jul 31.

Centre for Protein Science, Design and Engineering, Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Sector 81, SAS Nagar, Manauli, Mohali 140306, Punjab, India. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00039861153002
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http://dx.doi.org/10.1016/j.abb.2015.07.019DOI Listing
October 2015

Revisiting the membrane interaction mechanism of a membrane-damaging β-barrel pore-forming toxin Vibrio cholerae cytolysin.

Mol Microbiol 2015 Sep 4;97(6):1051-62. Epub 2015 Jul 4.

Centre for Protein Science, Design and Engineering, Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Sector 81, SAS Nagar, Manauli, Mohali, Punjab, 140306, India.

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http://doi.wiley.com/10.1111/mmi.13084
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http://dx.doi.org/10.1111/mmi.13084DOI Listing
September 2015

Signaling beyond Punching Holes: Modulation of Cellular Responses by Vibrio cholerae Cytolysin.

Toxins (Basel) 2015 Aug 21;7(8):3344-58. Epub 2015 Aug 21.

Centre for Protein Science, Design and Engineering, Department of Biological Sciences Indian Institute of Science Education and Research Mohali Sector 81, S. A. S. Nagar, Manauli PO 140306, Punjab, India.

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http://dx.doi.org/10.3390/toxins7083344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549754PMC
August 2015

Helicobacter pylori TlyA Forms Amyloid-like Aggregates with Potent Cytotoxic Activity.

Biochemistry 2015 Jun 8;54(23):3649-59. Epub 2015 Jun 8.

Centre for Protein Science, Design and Engineering, Department of Biological Sciences, Indian Institute of Science Education and Research Mohali, Sector 81, S. A. S. Nagar, Manauli 140306, Punjab, India.

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http://dx.doi.org/10.1021/acs.biochem.5b00423DOI Listing
June 2015

Vibrio cholerae cytolysin: structure-function mechanism of an atypical β-barrel pore-forming toxin.

Adv Exp Med Biol 2015 ;842:109-25

Centre for Protein Science, Design and Engineering, Department of Biological Sciences, Indian Institute of Science Education and Research (IISER), Mohali, Sector 81, Knowledge City, SAS Nagar, Mohali, Manauli, 140306, Punjab, India.

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http://dx.doi.org/10.1007/978-3-319-11280-0_7DOI Listing
May 2015

Transmembrane oligomeric form of Vibrio cholerae cytolysin triggers TLR2/TLR6-dependent proinflammatory responses in monocytes and macrophages.

Biochem J 2015 Feb;466(1):147-61

*Centre for Protein Science, Design and Engineering, Department of Biological Sciences, Indian Institute of Science Education and Research, Mohali, Punjab, India.

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http://biochemj.org/lookup/doi/10.1042/BJ20140718
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http://dx.doi.org/10.1042/BJ20140718DOI Listing
February 2015

Trapping of Vibrio cholerae cytolysin in the membrane-bound monomeric state blocks membrane insertion and functional pore formation by the toxin.

J Biol Chem 2014 Jun 2;289(24):16978-87. Epub 2014 May 2.

From the Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Sector 81, SAS Nagar, Manauli, Mohali, 140306 Punjab, India

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http://dx.doi.org/10.1074/jbc.M114.567099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059140PMC
June 2014

Helicobacter pylori TlyA agglutinates liposomes and induces fusion and permeabilization of the liposome membranes.

Biochemistry 2014 Jun 30;53(22):3553-63. Epub 2014 May 30.

Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Mohali , Sector 81, SAS Nagar, Manauli 140306, Punjab, India.

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http://dx.doi.org/10.1021/bi500152nDOI Listing
June 2014

Functional characterization of Helicobacter pylori TlyA: pore-forming hemolytic activity and cytotoxic property of the protein.

Biochem Biophys Res Commun 2014 Feb 14;444(2):153-7. Epub 2014 Jan 14.

Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Sector 81, SAS Nagar, Manauli, 140306 Punjab, India. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2014.01.011DOI Listing
February 2014

Pre-pore oligomer formation by Vibrio cholerae cytolysin: insights from a truncated variant lacking the pore-forming pre-stem loop.

Biochem Biophys Res Commun 2014 Jan 26;443(1):189-93. Epub 2013 Nov 26.

Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Sector 81, SAS Nagar, Manauli 140306, Punjab, India. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X130197
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http://dx.doi.org/10.1016/j.bbrc.2013.11.078DOI Listing
January 2014

Functional mapping of the lectin activity site on the β-prism domain of vibrio cholerae cytolysin: implications for the membrane pore-formation mechanism of the toxin.

J Biol Chem 2013 Jan 3;288(3):1665-73. Epub 2012 Dec 3.

Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Sector 81, SAS Nagar, Manauli, 140306, Punjab, India.

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http://dx.doi.org/10.1074/jbc.M112.430181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548476PMC
January 2013

Single point mutation in Vibrio cholerae cytolysin compromises the membrane pore-formation mechanism of the toxin.

FEBS J 2012 Nov 27;279(21):4039-51. Epub 2012 Sep 27.

Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Mohali, SAS Nagar, Manauli, Punjab, India.

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http://doi.wiley.com/10.1111/j.1742-4658.2012.08809.x
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http://dx.doi.org/10.1111/j.1742-4658.2012.08809.xDOI Listing
November 2012

Refolding and functional assembly of the Vibrio cholerae porin OmpU recombinantly expressed in the cytoplasm of Escherichia coli.

Protein Expr Purif 2012 Oct 17;85(2):204-10. Epub 2012 Aug 17.

Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Sector 81, SAS Nagar, Manauli, Punjab, India.

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http://dx.doi.org/10.1016/j.pep.2012.08.005DOI Listing
October 2012

Unfolding distinguishes the Vibrio cholerae cytolysin precursor from the mature form of the toxin.

Biochemistry 2011 May 25;50(19):3936-45. Epub 2011 Apr 25.

Indian Institute of Science Education and Research Mohali, Transit Campus: MGSIPAP Complex, Sector 26, Chandigarh 160019, India.

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http://dx.doi.org/10.1021/bi200332gDOI Listing
May 2011

1.8 A structure of murine GITR ligand dimer expressed in Drosophila melanogaster S2 cells.

Acta Crystallogr D Biol Crystallogr 2009 May 18;65(Pt 5):434-9. Epub 2009 Apr 18.

Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1107/S0907444909005721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672815PMC
May 2009

Focus on antivirally active sulfated polysaccharides: from structure-activity analysis to clinical evaluation.

Glycobiology 2009 Jan 24;19(1):2-15. Epub 2008 Sep 24.

Department of Chemistry, Natural Products Laboratory, University of Burdwan, WB 713 104, India.

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https://academic.oup.com/glycob/article-lookup/doi/10.1093/g
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http://dx.doi.org/10.1093/glycob/cwn092DOI Listing
January 2009

Polysaccharides from Gracilaria corticata: sulfation, chemical characterization and anti-HSV activities.

Int J Biol Macromol 2008 Nov 23;43(4):346-51. Epub 2008 Jul 23.

Natural Products Laboratory, Department of Chemistry, The University of Burdwan, WB 713 104, India.

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http://dx.doi.org/10.1016/j.ijbiomac.2008.07.009DOI Listing
November 2008

Anti-herpetic activity of a sulfated xylomannan from Scinaia hatei.

Phytochemistry 2008 Aug 21;69(11):2193-9. Epub 2008 Jun 21.

Natural Products Laboratory, Department of Chemistry, The University of Burdwan, Golapbag, Burdwan, West Bengal 713 104, India.

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http://dx.doi.org/10.1016/j.phytochem.2008.05.004DOI Listing
August 2008

Evolution of GITRL immune function: murine GITRL exhibits unique structural and biochemical properties within the TNF superfamily.

Proc Natl Acad Sci U S A 2008 Jan 8;105(2):635-40. Epub 2008 Jan 8.

Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1073/pnas.0710529105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206588PMC
January 2008

Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function.

Proc Natl Acad Sci U S A 2007 Dec 26;104(49):19452-7. Epub 2007 Nov 26.

Departments of Microbiology and Immunology, Cell Biology, Biochemistry, Physiology and Biophysics, Medicine (Division of Endocrinology), Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1073/pnas.0709264104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2148310PMC
December 2007

Structural features and antiviral activity of sulphated fucans from the brown seaweed Cystoseira indica.

Antivir Chem Chemother 2007 ;18(3):153-62

Natural Products Laboratory, Department of Chemistry, The University of Burdwan, WB, India.

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http://dx.doi.org/10.1177/095632020701800305DOI Listing
September 2007

Galactan sulfate of Grateloupia indica: Isolation, structural features and antiviral activity.

Phytochemistry 2007 May 23;68(10):1428-35. Epub 2007 Apr 23.

Natural Products Laboratory, Department of Chemistry, The University of Burdwan, WB 713 104, India.

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http://dx.doi.org/10.1016/j.phytochem.2007.02.008DOI Listing
May 2007

Structure and antiviral activity of sulfated fucans from Stoechospermum marginatum.

Phytochemistry 2006 Nov;67(22):2474-82

Natural Products Laboratory, Department of Chemistry, The University of Burdwan, Golapbag, Burdwan, West Bengal 713 104, India.

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http://dx.doi.org/10.1016/j.phytochem.2006.05.024DOI Listing
November 2006

Structural basis of inducible costimulator ligand costimulatory function: determination of the cell surface oligomeric state and functional mapping of the receptor binding site of the protein.

J Immunol 2006 Sep;177(6):3920-9

Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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September 2006

Unfolding of Vibrio cholerae hemolysin induces oligomerization of the toxin monomer.

J Biol Chem 2003 Oct 23;278(40):38470-5. Epub 2003 Jul 23.

Division of Immunology and Vaccine Development, National Institute of Cholera And Enteric Diseases, Kolkata 700010, India.

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http://dx.doi.org/10.1074/jbc.M305965200DOI Listing
October 2003

Macrophage distinguishes Vibrio cholerae hemolysin from its protease insensitive oligomer by time dependent and selective expression of CD80-CD86.

Immunol Lett 2003 Oct;89(2-3):143-7

Division of Immunology and Vaccine Development, National Institute of Cholera and Enteric Diseases, P-33, CIT Road, Scheme XM, 700 010, Kolkata, India.

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October 2003

Vibrio cholerae hemolysin. Implication of amphiphilicity and lipid-induced conformational change for its pore-forming activity.

Eur J Biochem 2002 Sep;269(17):4351-8

National Institute of Cholera and Enteric Diseases, Kolkata 700 010, India; Indian Institute of Chemical Biology, Kolkata 700 032, India.

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September 2002