Katrien De Bock

Katrien De Bock

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Katrien De Bock

Publications by authors named "Katrien De Bock"

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Exercise promotes satellite cell contribution to myofibers in a load-dependent manner.

Skelet Muscle 2020 Jul 9;10(1):21. Epub 2020 Jul 9.

Department Health Sciences and Technology, Laboratory of Exercise and Health, Swiss Federal Institute of Technology (ETH) Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1186/s13395-020-00237-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346400PMC
July 2020

Corrigendum to "The effect of resistance training, detraining and retraining on muscle strength and power, myofibre size, satellite cells and myonuclei in older men" [Exp. Gerontol., 133, 2020, 110860].

Exp Gerontol 2020 Jun 6;134:110897. Epub 2020 Mar 6.

Physical Activity, Sports & Health Research Group, Department of Movement Sciences, KU Leuven - University of Leuven, Tervuursevest 101, Box 1500, 3001 Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.exger.2020.110897DOI Listing
June 2020

Hallmarks of frailty and osteosarcopenia in prematurely aged PolgA mice.

J Cachexia Sarcopenia Muscle 2020 Jun 28. Epub 2020 Jun 28.

Institute for Biomechanics, ETH Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1002/jcsm.12588DOI Listing
June 2020

The effect of resistance training, detraining and retraining on muscle strength and power, myofibre size, satellite cells and myonuclei in older men.

Exp Gerontol 2020 May 1;133:110860. Epub 2020 Feb 1.

Physical Activity, Sport & Health Research Group, Department of Movement Sciences, KU Leuven - University of Leuven, Tervuursevest 101, Box 1500, 3001 Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.exger.2020.110860DOI Listing
May 2020

Corticospinal Control of Human Locomotion as a New Determinant of Age-Related Sarcopenia: An Exploratory Study.

J Clin Med 2020 Mar 6;9(3). Epub 2020 Mar 6.

Department of Health Sciences and Technology, Institute of Human Movement Sciences and Sport, ETH Zurich, 8093 Zurich, Switzerland.

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http://dx.doi.org/10.3390/jcm9030720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141202PMC
March 2020

PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase.

Nat Commun 2020 01 10;11(1):174. Epub 2020 Jan 10.

Department Health Sciences and Technology, Laboratory of Exercise and Health, Swiss Federal Institute of Technology (ETH) Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1038/s41467-019-13889-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954236PMC
January 2020

Voluntary Resistance Running as a Model to Induce mTOR Activation in Mouse Skeletal Muscle.

Front Physiol 2019 4;10:1271. Epub 2019 Oct 4.

Laboratory of Exercise and Health, Department of Health Sciences and Technology, Swiss Federal Institute of Technology (ETH) Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.3389/fphys.2019.01271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787551PMC
October 2019

Restoration of histone acetylation ameliorates disease and metabolic abnormalities in a FUS mouse model.

Acta Neuropathol Commun 2019 07 5;7(1):107. Epub 2019 Jul 5.

Department of Neurosciences, Experimental Neurology, and Leuven Brain Institute (LBI), KU Leuven - University of Leuven, Herestraat 49, 3000, Leuven, Belgium.

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http://dx.doi.org/10.1186/s40478-019-0750-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612190PMC
July 2019

Measuring Glycolytic and Mitochondrial Fluxes in Endothelial Cells Using Radioactive Tracers.

Methods Mol Biol 2019 ;1862:121-136

Laboratory of Exercise and Health, Department of Health Sciences and Technology, ETH Zürich, Zürich, Switzerland.

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http://link.springer.com/10.1007/978-1-4939-8769-6_9
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http://dx.doi.org/10.1007/978-1-4939-8769-6_9DOI Listing
June 2019

Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis.

Cell Metab 2018 12 23;28(6):881-894.e13. Epub 2018 Aug 23.

Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 51006, Guangdong, P.R. China; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.07.016DOI Listing
December 2018

The Warburg Effect in Endothelial Cells and its Potential as an Anti-angiogenic Target in Cancer.

Front Cell Dev Biol 2018 11;6:100. Epub 2018 Sep 11.

Laboratory of Exercise and Health, Department of Health Sciences and Technology, Swiss Federal Institute of Technology Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.3389/fcell.2018.00100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141712PMC
September 2018

Energy metabolism in ALS: an underappreciated opportunity?

Acta Neuropathol 2018 04 16;135(4):489-509. Epub 2018 Mar 16.

Department of Neurosciences, Experimental Neurology, KU Leuven-University of Leuven, Campus Gasthuisberg O&N 4, Herestraat 49, PB 602, 3000, Leuven, Belgium.

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http://dx.doi.org/10.1007/s00401-018-1835-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978930PMC
April 2018

Endothelial Cell Metabolism in Health and Disease.

Trends Cell Biol 2018 03 16;28(3):224-236. Epub 2017 Nov 16.

Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology, VIB, Leuven, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology, KU Leuven, Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.tcb.2017.10.010DOI Listing
March 2018

Premorbid obesity, but not nutrition, prevents critical illness-induced muscle wasting and weakness.

J Cachexia Sarcopenia Muscle 2017 Feb 20;8(1):89-101. Epub 2016 Jul 20.

Clinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, 3000, Leuven, Belgium.

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http://dx.doi.org/10.1002/jcsm.12131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326828PMC
February 2017

Breast Cancer-Derived Lung Metastases Show Increased Pyruvate Carboxylase-Dependent Anaplerosis.

Cell Rep 2016 10;17(3):837-848

Laboratory of Cellular Metabolism and Metabolic Regulation, Vesalius Research Center, VIB, Herestraat 49, 3000 Leuven, Belgium; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Herestraat 49, 3000 Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.09.042DOI Listing
October 2016

Metabolic control of the cell cycle.

Cell Cycle 2015 ;14(21):3379-88

a Laboratory of Angiogenesis and Neurovascular link; Department of Oncology; KU Leuven ; Leuven , Belgium.

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http://dx.doi.org/10.1080/15384101.2015.1090068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825590PMC
August 2016

Mitochondria in peroxisome-deficient hepatocytes exhibit impaired respiration, depleted DNA, and PGC-1α independent proliferation.

Biochim Biophys Acta 2015 Feb 20;1853(2):285-98. Epub 2014 Nov 20.

KU Leuven - University of Leuven, Department of Pharmaceutical and Pharmacological Sciences, Laboratory of Cell Metabolism, B-3000 Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2014.11.017DOI Listing
February 2015

Incomplete and transitory decrease of glycolysis: a new paradigm for anti-angiogenic therapy?

Cell Cycle 2014 13;13(1):16-22. Epub 2013 Dec 13.

Laboratory of Angiogenesis and Neurovascular Link; Vesalius Research Center; Department of Oncology; University of Leuven; Leuven, Belgium; Laboratory of Angiogenesis and Neurovascular Link; Vesalius Research Center; Department of Oncology; VIB; Leuven, Belgium.

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http://dx.doi.org/10.4161/cc.27519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925729PMC
September 2014

Tumor vessel normalization by chloroquine independent of autophagy.

Cancer Cell 2014 Aug;26(2):190-206

Department of Oncology, Laboratory of Angiogenesis and Neurovascular Link, KU Leuven, B-3000 Leuven, Belgium; Vesalius Research Center, Laboratory of Angiogenesis and Neurovascular Link, VIB, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1016/j.ccr.2014.06.025DOI Listing
August 2014

Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis.

Cell Metab 2014 Jan 12;19(1):37-48. Epub 2013 Dec 12.

Laboratory of Angiogenesis and Neurovascular link, Vesalius Research Center, Department of Oncology, University of Leuven, Leuven 3000, Belgium; Laboratory of Angiogenesis and Neurovascular link, Vesalius Research Center, VIB, Leuven 3000, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2013.11.008DOI Listing
January 2014

Control of vessel sprouting by genetic and metabolic determinants.

Trends Endocrinol Metab 2013 Dec 27;24(12):589-96. Epub 2013 Sep 27.

Laboratory of Angiogenesis and Neurovascular Link, Vesalius Research Center, Vlaams Instituut voor Biotechnologie (VIB), Department of Oncology, Katholieke Universiteit Leuven (KU Leuven), Herestraat 49, 3000 Leuven, Belgium.

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http://dx.doi.org/10.1016/j.tem.2013.08.006DOI Listing
December 2013

Role of endothelial cell metabolism in vessel sprouting.

Cell Metab 2013 Nov 22;18(5):634-47. Epub 2013 Aug 22.

Department of Oncology, University of Leuven, Laboratory of Angiogenesis and Neurovascular Link, Vesalius Research Center, Leuven 3000, Belgium; VIB, Laboratory of Angiogenesis and Neurovascular Link, Vesalius Research Center, Leuven 3000, Belgium.

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http://dx.doi.org/10.1016/j.cmet.2013.08.001DOI Listing
November 2013

Treating diabetes by blocking a vascular growth factor.

Cell Metab 2012 Nov;16(5):553-5

Department of Oncology, University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1016/j.cmet.2012.10.015DOI Listing
November 2012

Exercise-induced, but not creatine-induced, decrease in intramyocellular lipid content improves insulin sensitivity in rats.

J Nutr Biochem 2011 Dec 17;22(12):1178-85. Epub 2011 Feb 17.

Department of Biomedical Kinesiology, Research Centre for Exercise and Health, KU Leuven, Tervuursevest 101, B-3001 Leuven, Belgium.

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https://linkinghub.elsevier.com/retrieve/pii/S09552863100025
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http://dx.doi.org/10.1016/j.jnutbio.2010.10.004DOI Listing
December 2011

Antiangiogenic therapy, hypoxia, and metastasis: risky liaisons, or not?

Nat Rev Clin Oncol 2011 May 31;8(7):393-404. Epub 2011 May 31.

Laboratory of Angiogenesis and Neurovascular Link, Vesalius Research Center, VIB, KU Leuven, Campus Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium.

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http://dx.doi.org/10.1038/nrclinonc.2011.83DOI Listing
May 2011

Vessel abnormalization: another hallmark of cancer? Molecular mechanisms and therapeutic implications.

Curr Opin Genet Dev 2011 Feb 22;21(1):73-9. Epub 2010 Nov 22.

Vesalius Research Center, K.U.Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1016/j.gde.2010.10.008DOI Listing
February 2011

From vessel sprouting to normalization: role of the prolyl hydroxylase domain protein/hypoxia-inducible factor oxygen-sensing machinery.

Arterioscler Thromb Vasc Biol 2010 Dec 21;30(12):2331-6. Epub 2010 Oct 21.

Vesalius Research Center, Vlaams Instituut voor Biotechnologie, Katholieke Universiteit Leuven, Campus Gasthuisberg, Herestraat 49, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1161/ATVBAHA.110.214106DOI Listing
December 2010

Cafeteria diet-induced insulin resistance is not associated with decreased insulin signaling or AMPK activity and is alleviated by physical training in rats.

Am J Physiol Endocrinol Metab 2010 Aug 18;299(2):E215-24. Epub 2010 May 18.

Molecular Physiology Group, Department of Exercise and Sport Sciences, Copenhagen Muscle Research Centre, University of Copenhagen, 13 Universitetsparken, Copenhagen, Denmark.

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http://www.physiology.org/doi/10.1152/ajpendo.00098.2010
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http://dx.doi.org/10.1152/ajpendo.00098.2010DOI Listing
August 2010

Effectiveness of a lifestyle physical activity versus a structured exercise intervention in older adults.

J Aging Phys Act 2010 Jul;18(3):335-52

Dept. of Biomedical Kinesiology, Leuven Catholic University, Leuven, Belgium.

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http://dx.doi.org/10.1123/japa.18.3.335DOI Listing
July 2010

Hyperglycemic diet and training alter insulin sensitivity, intramyocellular lipid content but not UCP3 protein expression in rat skeletal muscles.

Int J Mol Med 2010 Jun;25(6):905-13

Department of Biomedical Kinesiology, Faculty of Kinesiology and Rehabilitation Sciences, Research Centre for Exercise and Health, K.U. Leuven, B-3001 Leuven, Belgium.

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http://dx.doi.org/10.3892/ijmm_00000421DOI Listing
June 2010

Increased p70s6k phosphorylation during intake of a protein-carbohydrate drink following resistance exercise in the fasted state.

Eur J Appl Physiol 2010 Mar;108(4):791-800

Department of Biomedical Kinesiology, Research Center for Exercise and Health, FABER, K.U.Leuven, Tervuursevest 101, 3001 Leuven (Heverlee), Belgium.

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http://dx.doi.org/10.1007/s00421-009-1289-xDOI Listing
March 2010

Androgen signaling in myocytes contributes to the maintenance of muscle mass and fiber type regulation but not to muscle strength or fatigue.

Endocrinology 2009 Aug 5;150(8):3558-66. Epub 2009 Mar 5.

Department ofExperimental Medicine, Laboratory for Experimental Medicine and Endocrinology, Katholieke Universiteit Leuven, B-3000 Leuven, Belgium.

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https://academic.oup.com/endo/article-lookup/doi/10.1210/en.
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http://dx.doi.org/10.1210/en.2008-1509DOI Listing
August 2009

Endothelial oxygen sensors regulate tumor vessel abnormalization by instructing phalanx endothelial cells.

J Mol Med (Berl) 2009 Jun 20;87(6):561-9. Epub 2009 May 20.

Vesalius Research Center, K.U. Leuven, Belgium.

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http://dx.doi.org/10.1007/s00109-009-0482-zDOI Listing
June 2009

Mechanisms of vessel branching: filopodia on endothelial tip cells lead the way.

Arterioscler Thromb Vasc Biol 2009 May 5;29(5):639-49. Epub 2009 Mar 5.

Vesalius Research Center, VIB, K.U. Leuven, Belgium.

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https://www.ahajournals.org/doi/10.1161/ATVBAHA.109.185165
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http://dx.doi.org/10.1161/ATVBAHA.109.185165DOI Listing
May 2009

Human sarcopenia reveals an increase in SOCS-3 and myostatin and a reduced efficiency of Akt phosphorylation.

Rejuvenation Res 2008 Feb;11(1):163-175B

Clinique romande de réadaptation SuvaCare, Sion, Switzerland.

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http://dx.doi.org/10.1089/rej.2007.0588DOI Listing
February 2008

ACTN3 (R577X) genotype is associated with fiber type distribution.

Physiol Genomics 2007 Dec 11;32(1):58-63. Epub 2007 Sep 11.

Research Centre for Exercise and Health, Department of Biomedical Kinesiology, Faculty of Kinesiology and Rehabilitation Sciences, Katholieke Universiteit Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1152/physiolgenomics.00173.2007DOI Listing
December 2007

Acute Rhodiola rosea intake can improve endurance exercise performance.

Int J Sport Nutr Exerc Metab 2004 Jun;14(3):298-307

Faculty of Physical Education and Physiotherapy in the Exercise Physiology and Biomechanics Laboratory at the Katholieke Universiteit Leuven, Tervuursevest 101, B-3001 Leuven, Belgium.

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http://dx.doi.org/10.1123/ijsnem.14.3.298DOI Listing
June 2004