Publications by authors named "Katja Dettmer"

90Publications

De novo polyamine synthesis supports metabolic and functional responses in activated murine NK cells.

Eur J Immunol 2020 Sep 18. Epub 2020 Sep 18.

School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1002/eji.202048784DOI Listing
September 2020

Library Selection with a Randomized Repertoire of (βα)-Barrel Enzymes Results in Unexpected Induction of Gene Expression.

Biochemistry 2019 10 7;58(41):4207-4217. Epub 2019 Oct 7.

Institute of Biophysics and Physical Biochemistry , University of Regensburg , Universitätsstrasse 31 , D-93053 Regensburg , Germany.

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http://dx.doi.org/10.1021/acs.biochem.9b00579DOI Listing
October 2019

Quantification and C-Tracer analysis of total reduced glutathione by HPLC-QTOFMS/MS.

Anal Chim Acta 2019 Nov 3;1080:127-137. Epub 2019 Jul 3.

Institute of Functional Genomics, University of Regensburg, Am BioPark 9, 93053, Regensburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.aca.2019.07.001DOI Listing
November 2019

Amino Acid Analysis in Physiological Samples by GC-MS with Propyl Chloroformate Derivatization and iTRAQ-LC-MS/MS.

Methods Mol Biol 2019 ;2030:173-190

Institute of Functional Genomics, University of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1007/978-1-4939-9639-1_14DOI Listing
April 2020

Degradation of D-2-hydroxyglutarate in the presence of isocitrate dehydrogenase mutations.

Sci Rep 2019 05 15;9(1):7436. Epub 2019 May 15.

Institute of Functional Genomics, University of Regensburg, Am BioPark 9, 93053, Regensburg, Germany.

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http://dx.doi.org/10.1038/s41598-019-43891-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520482PMC
May 2019

Limitation of TCA Cycle Intermediates Represents an Oxygen-Independent Nutritional Antibacterial Effector Mechanism of Macrophages.

Cell Rep 2019 03;26(13):3502-3510.e6

Mikrobiologisches Institut, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, 91054 Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.02.103DOI Listing
March 2019

Potential biomarkers to predict outcome of faecal microbiota transfer for recurrent Clostridioides difficile infection.

Dig Liver Dis 2019 07 26;51(7):944-951. Epub 2019 Jan 26.

Department I of Internal Medicine, University Hospital of Cologne, Germany; German Centre for Infection Research (DZIF), Partner Site Bonn-Cologne, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15908658193004
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http://dx.doi.org/10.1016/j.dld.2019.01.012DOI Listing
July 2019

Serotonin and tryptophan metabolites, autoantibodies and gut microbiome in APECED.

Endocr Connect 2019 Jan;8(1):69-77

Department of Dermatology, Allergology and Venereology, University of Helsinki, and Helsinki University Central Hospital, Helsinki, Finland.

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https://ec.bioscientifica.com/view/journals/ec/aop/ec-18-051
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http://dx.doi.org/10.1530/EC-18-0513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365670PMC
January 2019

Combined Modulation of Tumor Metabolism by Metformin and Diclofenac in Glioma.

Int J Mol Sci 2018 Aug 31;19(9). Epub 2018 Aug 31.

Department of Neurology and Wilhelm Sander-NeuroOncology Unit, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany.

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http://www.mdpi.com/1422-0067/19/9/2586
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http://dx.doi.org/10.3390/ijms19092586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163514PMC
August 2018

From Discovery to Translation: Characterization of C-Mannosyltryptophan and Pseudouridine as Markers of Kidney Function.

Sci Rep 2017 12 12;7(1):17400. Epub 2017 Dec 12.

Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Hugstetter Str. 49, 79106, Freiburg, Germany.

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http://dx.doi.org/10.1038/s41598-017-17107-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727198PMC
December 2017

Srebp-controlled glucose metabolism is essential for NK cell functional responses.

Nat Immunol 2017 Nov 18;18(11):1197-1206. Epub 2017 Sep 18.

School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Ireland.

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http://dx.doi.org/10.1038/ni.3838DOI Listing
November 2017

Biological and clinical significance of tryptophan-catabolizing enzymes in cutaneous T-cell lymphomas.

Oncoimmunology 2017 10;6(3):e1273310. Epub 2017 Feb 10.

Department of Dermatology and Allergology, University of Helsinki and Helsinki University Central Hospital , Helsinki, Finland.

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http://dx.doi.org/10.1080/2162402X.2016.1273310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384345PMC
February 2017

Quantification of Metabolites by NMR Spectroscopy in the Presence of Protein.

J Proteome Res 2017 04 24;16(4):1784-1796. Epub 2017 Mar 24.

Institute of Functional Genomics, University of Regensburg , Am Biopark 9, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1021/acs.jproteome.7b00057DOI Listing
April 2017

Renal Fanconi Syndrome Is Caused by a Mistargeting-Based Mitochondriopathy.

Cell Rep 2016 05 5;15(7):1423-1429. Epub 2016 May 5.

Institute of Functional Genomics, University of Regensburg, 93053 Regensburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.04.037DOI Listing
May 2016

Optimizing the SWATH-MS-workflow for label-free proteomics.

J Proteomics 2016 08 21;145:137-140. Epub 2016 Apr 21.

Institute of Functional Genomics, University of Regensburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2016.04.021DOI Listing
August 2016

Quantitative Imaging of D-2-Hydroxyglutarate in Selected Histological Tissue Areas by a Novel Bioluminescence Technique.

Front Oncol 2016 7;6:46. Epub 2016 Mar 7.

Institute of Pathophysiology, University Medical Center of the Johannes Gutenberg University Mainz , Mainz , Germany.

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http://dx.doi.org/10.3389/fonc.2016.00046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779886PMC
March 2016

Ferritin-Mediated Iron Sequestration Stabilizes Hypoxia-Inducible Factor-1α upon LPS Activation in the Presence of Ample Oxygen.

Cell Rep 2015 Dec 25;13(10):2048-55. Epub 2015 Nov 25.

Mikrobiologisches Institut - Klinische Mikrobiologie, Immunologie und Hygiene, Universitätsklinikum Erlangen and Friedrich-Alexander Universität (FAU) Erlangen-Nürnberg, 91054 Erlangen, Germany; Institute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg, 93053 Regensburg, Germany. Electronic address:

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http://www.cell.com/cms/attachment/2041386719/2055161577/mmc
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http://linkinghub.elsevier.com/retrieve/pii/S221112471501292
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http://dx.doi.org/10.1016/j.celrep.2015.11.005DOI Listing
December 2015

Enhanced metabolite profiling using a redesigned atmospheric pressure chemical ionization source for gas chromatography coupled to high-resolution time-of-flight mass spectrometry.

Anal Bioanal Chem 2015 Sep 21;407(22):6669-80. Epub 2015 Jun 21.

Institute of Functional Genomics, University of Regensburg, Josef-Engert-Str. 9, 93053, Regensburg, Germany.

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http://dx.doi.org/10.1007/s00216-015-8824-xDOI Listing
September 2015

Continuous water infusion enhances atmospheric pressure chemical ionization of methyl chloroformate derivatives in gas chromatography coupled to time-of-flight mass spectrometry-based metabolomics.

Anal Chem 2014 Sep 3;86(18):9186-95. Epub 2014 Sep 3.

Institute of Functional Genomics, University of Regensburg , Josef-Engert-Strasse 9, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1021/ac502133rDOI Listing
September 2014

Assessment of ionic liquid stationary phases for the GC analysis of fatty acid methyl esters.

Authors:
Katja Dettmer

Anal Bioanal Chem 2014 Aug 26;406(20):4931-9. Epub 2014 Jun 26.

Institute of Functional Genomics, University of Regensburg, Josef-Engert-Str. 9, 93053, Regensburg, Germany,

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http://dx.doi.org/10.1007/s00216-014-7919-0DOI Listing
August 2014

Inducing anti-tumor cytokines and an immune response in melanoma by inhibition of MIA using the peptide AR71.

Eur J Dermatol 2013 Nov-Dec;23(6):820-5

Institute of Pathology, University of Regensburg Franz-Josef-Strauss-Allee 11 D-93053 Regensburg, Germany.

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http://dx.doi.org/10.1684/ejd.2013.2234DOI Listing
February 2015

Mistargeting of peroxisomal EHHADH and inherited renal Fanconi's syndrome.

N Engl J Med 2014 Jan;370(2):129-38

From the Centre for Nephrology (E.D.K., H.C.S., D.B., G.J., H.C., A.M.H., R.J.U., R.K.) and Institute of Child Health (D.B., R.K.), University College London, and Biomolecular Medicine, Imperial College London (S.L.R., A.D.W., E.H., J.K.N.) - both in London; the Departments of Medical Cell Biology (M.R., C.B., D.P., C.S., R. Warth), Internal Medicine III (K.R.), Internal Medicine II (S.W.R.), and Molecular and Cellular Anatomy (R. Witzgall) and the Institutes of Functional Genomics (J.R., K.E., N.A., P.J.O., K.D.) and Pathology (J.S.), University of Regensburg, and the Department of Radiology, Barmherzige Brueder Hospital (N.Z.) - all in Regensburg, Germany; the National Human Genome Research Institute (A.H.-W., S.L.R., H.C.S., K.O., I.B., D.M.K., W.A.G., R.K.) and National Heart, Lung, and Blood Institute (Y.I.), National Institutes of Health, Bethesda, MD; the Division of Pediatric Nephrology, University of Florida, Jacksonville (A.T., M.I.); the Genome Biology Department, Australian National University, Canberra, ACT, Australia (M.A.-B.); Kitasato University Medical Center, Saitama, Japan (H.N.); and the Department of Pathology, Northwestern University, Chicago (Y.J., J.K.R.).

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http://dx.doi.org/10.1056/NEJMoa1307581DOI Listing
January 2014

Correlations between milk and plasma levels of amino and carboxylic acids in dairy cows.

J Proteome Res 2013 Nov 23;12(11):5223-32. Epub 2013 Aug 23.

Institute of Functional Genomics, University of Regensburg , Regensburg, Germany.

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http://dx.doi.org/10.1021/pr4006537DOI Listing
November 2013

Distinct metabolic differences between various human cancer and primary cells.

Electrophoresis 2013 Oct 12;34(19):2836-47. Epub 2013 Sep 12.

Institute of Functional Genomics, University of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1002/elps.201300228DOI Listing
October 2013

Early changes in the liver-soluble proteome from mice fed a nonalcoholic steatohepatitis inducing diet.

Proteomics 2012 May;12(9):1437-51

Institute of Functional Genomics, University of Regensburg, Josef-Engert-Strasse 9, Regensburg, Germany.

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http://doi.wiley.com/10.1002/pmic.201100628
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http://dx.doi.org/10.1002/pmic.201100628DOI Listing
May 2012

Comprehensive two-dimensional gas chromatography in metabolomics.

Anal Bioanal Chem 2012 Feb 17;402(6):1993-2013. Epub 2012 Jan 17.

Institute of Functional Genomics, University of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1007/s00216-011-5630-yDOI Listing
February 2012

Metabolic fingerprinting using comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry.

Methods Mol Biol 2012 ;815:399-411

Institute of Functional Genomics, University of Regensburg, Josef-Engert-Str. 9, Regensburg 93053, Germany.

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http://dx.doi.org/10.1007/978-1-61779-424-7_29DOI Listing
March 2012

Amino acid analysis in physiological samples by GC-MS with propyl chloroformate derivatization and iTRAQ-LC-MS/MS.

Methods Mol Biol 2012 ;828:165-81

Institute of Functional Genomics, University of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1007/978-1-61779-445-2_15DOI Listing
March 2012

Comparison of two algorithmic data processing strategies for metabolic fingerprinting by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry.

J Chromatogr A 2011 Sep 12;1218(39):7031-8. Epub 2011 Aug 12.

Institute of Functional Genomics, University of Regensburg, Josef-Engert-Str. 9, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1016/j.chroma.2011.08.006DOI Listing
September 2011

Performance evaluation of gas chromatography-atmospheric pressure chemical ionization-time-of-flight mass spectrometry for metabolic fingerprinting and profiling.

Anal Chem 2011 Oct 9;83(19):7514-22. Epub 2011 Sep 9.

Institute of Functional Genomics, University of Regensburg, Josef-Engert-Straße 9, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1021/ac201719dDOI Listing
October 2011

Metabolite extraction from adherently growing mammalian cells for metabolomics studies: optimization of harvesting and extraction protocols.

Anal Bioanal Chem 2011 Jan 2;399(3):1127-39. Epub 2010 Dec 2.

Institute of Functional Genomics, University of Regensburg, Josef-Engert-Str. 9, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1007/s00216-010-4425-xDOI Listing
January 2011

Comparison of serum versus plasma collection in gas chromatography--mass spectrometry-based metabolomics.

Electrophoresis 2010 Jul;31(14):2365-73

Institute of Functional Genomics, University of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1002/elps.200900778DOI Listing
July 2010

Comparison of derivatization and chromatographic methods for GC-MS analysis of amino acid enantiomers in physiological samples.

J Chromatogr B Analyt Technol Biomed Life Sci 2010 May 18;878(15-16):1103-12. Epub 2010 Mar 18.

Institute of Functional Genomics, University of Regensburg, Josef-Engert-Strasse 9, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1016/j.jchromb.2010.03.021DOI Listing
May 2010

Quantification of intermediates of the methionine and polyamine metabolism by liquid chromatography-tandem mass spectrometry in cultured tumor cells and liver biopsies.

J Chromatogr A 2010 May 18;1217(19):3282-8. Epub 2010 Jan 18.

Institute of Functional Genomics, University of Regensburg, Josef-Engert-Str 9, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1016/j.chroma.2010.01.025DOI Listing
May 2010

Urinary metabolite quantification employing 2D NMR spectroscopy.

Anal Chem 2008 Dec;80(23):9288-97

Institute of Functional Genomics, University of Regensburg, Josef-Engert-Strasse 9, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1021/ac801627cDOI Listing
December 2008

Urinary amino acid analysis: a comparison of iTRAQ-LC-MS/MS, GC-MS, and amino acid analyzer.

J Chromatogr B Analyt Technol Biomed Life Sci 2009 Jul 15;877(20-21):1838-46. Epub 2009 May 15.

Institute of Functional Genomics, University of Regensburg, Josef-Engert-Strasse 9, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1016/j.jchromb.2009.05.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748257PMC
July 2009

Capillary electrophoresis and column chromatography in biomedical chiral amino acid analysis.

Anal Bioanal Chem 2009 Jun 25;394(3):695-706. Epub 2009 Apr 25.

Institute of Functional Genomics, University of Regensburg, 93053, Regensburg, Germany.

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http://dx.doi.org/10.1007/s00216-009-2792-yDOI Listing
June 2009

Direct and tumor microenvironment mediated influences of 5'-deoxy-5'-(methylthio)adenosine on tumor progression of malignant melanoma.

J Cell Biochem 2009 Feb;106(2):210-9

Institute of Functional Genomics, University of Regensburg Medical School, Josef-Engert-Str. 9, D-93053 Regensburg, Germany.

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http://dx.doi.org/10.1002/jcb.21984DOI Listing
February 2009

Quantitative analysis of 5'-deoxy-5'-methylthioadenosine in melanoma cells by liquid chromatography-stable isotope ratio tandem mass spectrometry.

J Chromatogr B Analyt Technol Biomed Life Sci 2008 Dec 30;876(1):123-8. Epub 2008 Oct 30.

Institute of Functional Genomics, University of Regensburg, Josef-Engert-Strasse 9, Regensburg, Germany.

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http://dx.doi.org/10.1016/j.jchromb.2008.10.038DOI Listing
December 2008

Advances in amino acid analysis.

Anal Bioanal Chem 2009 Jan 9;393(2):445-52. Epub 2008 Oct 9.

Institute of Functional Genomics, University of Regensburg, 93053, Regensburg, Germany.

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http://link.springer.com/10.1007/s00216-008-2421-1
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http://dx.doi.org/10.1007/s00216-008-2421-1DOI Listing
January 2009

Automated GC-MS analysis of free amino acids in biological fluids.

J Chromatogr B Analyt Technol Biomed Life Sci 2008 Jul 18;870(2):222-32. Epub 2008 Jun 18.

Institute of Functional Genomics, University of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1016/j.jchromb.2008.06.018DOI Listing
July 2008

Hyphenated mass spectrometry in the analysis of the central carbon metabolism.

Anal Bioanal Chem 2008 Jun 15;391(3):895-8. Epub 2008 Apr 15.

Institute of Functional Genomics, University of Regensburg, Josef-Engert-Str. 9, 93053, Regensburg, Germany.

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http://dx.doi.org/10.1007/s00216-008-2084-yDOI Listing
June 2008

On the occasion of Professor Werner Engewald's 70th birthday.

Authors:
Katja Dettmer

Anal Bioanal Chem 2007 Aug;388(8):1631-2

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http://dx.doi.org/10.1007/s00216-007-1380-2DOI Listing
August 2007

The role of inflammatory mediators in the synergistic toxicity of ozone and 1-nitronaphthalene in rat airways.

Environ Health Perspect 2006 Sep;114(9):1354-60

Department of Entomology and Cancer Research Center, University of California, Davis, California, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570074PMC
http://dx.doi.org/10.1289/ehp.8373DOI Listing
September 2006

Mass spectrometry-based metabolomics.

Mass Spectrom Rev 2007 Jan-Feb;26(1):51-78

Department of Entomology, University of California at Davis, Davis, California 95616, USA.

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http://dx.doi.org/10.1002/mas.20108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904337PMC
January 2007