Katie Lunnon

Katie Lunnon

UNVERIFIED PROFILE

Are you Katie Lunnon?   Register this Author

Register author
Katie Lunnon

Katie Lunnon

Publications by authors named "Katie Lunnon"

Are you Katie Lunnon?   Register this Author

53Publications

1608Reads

37Profile Views

Neuroepigenetics of Aging and Age-Related Neurodegenerative Disorders.

Prog Mol Biol Transl Sci 2018 5;158:49-82. Epub 2018 Jun 5.

Department of Psychiatry and Neuropsychology, Maastricht University Medical Centre, Maastricht, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/bs.pmbts.2018.04.008DOI Listing
July 2019

Alzheimer's Disease Associated Genes Ankyrin and Tau Cause Shortened Lifespan and Memory Loss in .

Front Cell Neurosci 2019 11;13:260. Epub 2019 Jun 11.

School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fncel.2019.00260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581016PMC
June 2019

Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer's disease.

Clin Epigenetics 2019 03 21;11(1):52. Epub 2019 Mar 21.

College of Medicine and Health, University of Exeter Medical School, Exeter University, RILD Building Level 4, Royal Devon and Exeter Hospital, Barrack Rd, Exeter, EX2 5DW, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13148-019-0636-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429761PMC
March 2019

A cross-brain regions study of ANK1 DNA methylation in different neurodegenerative diseases.

Neurobiol Aging 2019 02 13;74:70-76. Epub 2018 Oct 13.

University of Exeter Medical School, University of Bristol, Exeter, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2018.09.024DOI Listing
February 2019

Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology.

Alzheimers Dement 2018 12 15;14(12):1580-1588. Epub 2018 Mar 15.

Institute of Clinical and Biomedical Science, University of Exeter Medical School, RILD Building, Royal Devon & Exeter Hospital Campus, Exeter, Devon, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jalz.2018.01.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438205PMC
December 2018

Regional differences in mitochondrial DNA methylation in human post-mortem brain tissue.

Clin Epigenetics 2017 3;9:47. Epub 2017 May 3.

University of Exeter Medical School, RILD, University of Exeter, Barrack Road, Devon, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13148-017-0337-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415779PMC
January 2018

Using induced pluripotent stem cells to explore genetic and epigenetic variation associated with Alzheimer's disease.

Epigenomics 2017 11 3;9(11):1455-1468. Epub 2017 Oct 3.

Institute of Clinical and Biomedical Science, University of Exeter Medical School, Exeter University, Exeter, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/epi-2017-0076DOI Listing
November 2017

Epigenetics and DNA methylomic profiling in Alzheimer's disease and other neurodegenerative diseases.

J Neurochem 2017 10 21;143(2):158-170. Epub 2017 Sep 21.

University of Exeter Medical School, University of Exeter, Devon, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jnc.14148DOI Listing
October 2017

DNA Modifications and Alzheimer's Disease.

Adv Exp Med Biol 2017 ;978:303-319

University of Exeter Medical School, RILD, Barrack Road, Exeter, Devon, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-3-319-53889-1_16DOI Listing
September 2017

ANK1 is up-regulated in laser captured microglia in Alzheimer's brain; the importance of addressing cellular heterogeneity.

PLoS One 2017 12;12(7):e0177814. Epub 2017 Jul 12.

Biodesign, ASU-Banner Biodesign Neurodegenerative Disease Research Center, and School of Life Sciences, Arizona State University, Tempe, AZ, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0177814PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507536PMC
September 2017

Genetic architecture of epigenetic and neuronal ageing rates in human brain regions.

Nat Commun 2017 05 18;8:15353. Epub 2017 May 18.

Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms15353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454371PMC
May 2017

Tissue-specific patterns of allelically-skewed DNA methylation.

Epigenetics 2016 19;11(1):24-35. Epub 2016 Jan 19.

a Institute of Psychiatry, Psychology and Neuroscience, King's College London , London , UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15592294.2015.1127479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846124PMC
December 2016

Increased DNA methylation near TREM2 is consistently seen in the superior temporal gyrus in Alzheimer's disease brain.

Neurobiol Aging 2016 11 16;47:35-40. Epub 2016 Jul 16.

Institute of Biomedical and Clinical Science, University of Exeter Medical School, RILD, University of Exeter, Devon, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2016.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747529PMC
November 2016

Epigenetic regulation of mitochondrial function in neurodegenerative disease: New insights from advances in genomic technologies.

Neurosci Lett 2016 06 10;625:47-55. Epub 2016 Feb 10.

Institute of Clinical and Biomedical Science, University of Exeter Medical School, University of Exeter, Devon, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neulet.2016.02.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747527PMC
June 2016

Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum.

Nat Commun 2016 Feb 2;7:10561. Epub 2016 Feb 2.

Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms10561DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740877PMC
February 2016

Variation in 5-hydroxymethylcytosine across human cortex and cerebellum.

Genome Biol 2016 Feb 16;17:27. Epub 2016 Feb 16.

University of Exeter Medical School, RILD, University of Exeter, Barrack Road, Devon, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13059-016-0871-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756397PMC
February 2016

The mitochondrial epigenome: a role in Alzheimer's disease?

Epigenomics 2014 ;6(6):665-75

University of Exeter Medical School, RILD Level 4, Barrack Road, Exeter, Devon, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/epi.14.50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329914PMC
August 2015

Blood methylomic signatures of presymptomatic dementia in elderly subjects with type 2 diabetes mellitus.

Neurobiol Aging 2015 Mar 24;36(3):1600.e1-4. Epub 2014 Dec 24.

The Joseph Sagol Neuroscience Center, Sheba Medical Center, Ramat Gan, Israel; Department of Psychiatry, The Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2014.12.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747361PMC
March 2015

Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer's disease brain.

Neurobiol Aging 2014 Aug 6;35(8):1850-4. Epub 2014 Feb 6.

Institute of Biomedical & Clinical Science, University of Exeter Medical School, University of Exeter, Devon, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2014.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066184PMC
August 2014

Inflammatory proteins in plasma are associated with severity of Alzheimer's disease.

PLoS One 2013 10;8(6):e64971. Epub 2013 Jun 10.

King's College London and National Institute for Health Research-NIHR, Biomedical Research Centres at South London and Maudsley NHS Foundation Trust and Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0064971PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677891PMC
February 2014

Epigenetic studies in Alzheimer's disease: current findings, caveats, and considerations for future studies.

Am J Med Genet B Neuropsychiatr Genet 2013 Dec 13;162B(8):789-99. Epub 2013 Sep 13.

University of Exeter Medical School, University of Exeter, Devon, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajmg.b.32201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947441PMC
December 2013

A data-driven approach to preprocessing Illumina 450K methylation array data.

BMC Genomics 2013 May 1;14:293. Epub 2013 May 1.

Social, Genetic and Developmental Psychiatry, Institute of Psychiatry, King's College London, De Crespigny Park, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2164-14-293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769145PMC
May 2013

Systemic inflammation modulates Fc receptor expression on microglia during chronic neurodegeneration.

J Immunol 2011 Jun 13;186(12):7215-24. Epub 2011 May 13.

Central Nervous System Inflammation Group, School of Biological Sciences, University of Southampton, Southampton SO16 6YD, United Kingdom.

View Article

Download full-text PDF

Source
http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.0903833
Publisher Site
http://dx.doi.org/10.4049/jimmunol.0903833DOI Listing
June 2011

Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease.

Biol Psychiatry 2009 Feb 18;65(4):304-12. Epub 2008 Sep 18.

Department of Biochemistry, Trinity College Institute of Neuroscience, Trinity College Dublin, Republic of Ireland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biopsych.2008.07.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633437PMC
February 2009