Publications by authors named "Kathryn R Barber"

20Publications

The mammalian CTLH complex is an E3 ubiquitin ligase that targets its subunit muskelin for degradation.

Sci Rep 2019 07 8;9(1):9864. Epub 2019 Jul 8.

Robarts Research Institute, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Ontario, Canada.

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July 2019

A subset of calcium-binding S100 proteins show preferential heterodimerization.

FEBS J 2019 05 21;286(10):1859-1876. Epub 2019 Feb 21.

Department of Biochemistry, The University of Western Ontario, London, Canada.

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May 2019

Regulation of Shigella Effector Kinase OspG through Modulation of Its Dynamic Properties.

J Mol Biol 2018 07 16;430(14):2096-2112. Epub 2018 May 16.

Department of Biochemistry, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada; Department of Biochemistry, McGill University, Montreal, Quebec, Canada. Electronic address:

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July 2018

Ubiquitin phosphorylated at Ser57 hyper-activates parkin.

Biochim Biophys Acta Gen Subj 2017 Nov 6;1861(11 Pt B):3038-3046. Epub 2017 Jul 6.

Department of Biochemistry, The University of Western Ontario, London, ON N6A 5C1, Canada; Department of Chemistry, The University of Western Ontario, London, ON N6A 5C1, Canada. Electronic address:

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November 2017

Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity.

Nat Struct Mol Biol 2017 May 17;24(5):475-483. Epub 2017 Apr 17.

MRC Protein Phosphorylation and Ubiquitylation Unit, College of Life Sciences, University of Dundee, Dundee, UK.

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May 2017

The HIP2~ubiquitin conjugate forms a non-compact monomeric thioester during di-ubiquitin synthesis.

PLoS One 2015 23;10(3):e0120318. Epub 2015 Mar 23.

Department of Biochemistry, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Ontario, Canada, N6A 5C1.

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February 2016

Structural basis for the inhibition of host protein ubiquitination by Shigella effector kinase OspG.

Structure 2014 Jun 22;22(6):878-88. Epub 2014 May 22.

Department of Biochemistry, University of Saskatchewan, 107 Wiggins Road, Saskatoon, SK S7N 5E5, Canada; Department of Biochemistry, McGill University, Montreal, QC H3G 1Y6, Canada. Electronic address:

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June 2014

Ataxin-3 is a multivalent ligand for the parkin Ubl domain.

Biochemistry 2013 Oct 9;52(42):7369-76. Epub 2013 Oct 9.

Department of Biochemistry, Schulich School of Medicine and Dentistry, University of Western Ontario , London, Ontario, Canada N6A 5C1.

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October 2013

A molecular explanation for the recessive nature of parkin-linked Parkinson's disease.

Nat Commun 2013 ;4:1983

Department of Biochemistry, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada N6A 5C1.

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December 2013

Structure of an asymmetric ternary protein complex provides insight for membrane interaction.

Structure 2012 Oct 30;20(10):1737-45. Epub 2012 Aug 30.

Department of Biochemistry, The University of Western Ontario, London, Ontario N6A 5C1, Canada.

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October 2012

Solution structure of the E3 ligase HOIL-1 Ubl domain.

Protein Sci 2012 Jul 24;21(7):1085-92. Epub 2012 May 24.

Department of Biochemistry, University of Western Ontario, London, Ontario N6A 5C1, Canada.

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July 2012

Autoregulation of Parkin activity through its ubiquitin-like domain.

EMBO J 2011 Jun 21;30(14):2853-67. Epub 2011 Jun 21.

Protein Structure and Function Laboratory, Cancer Research UK, London Research Institute, London, UK.

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June 2011

Impact of autosomal recessive juvenile Parkinson's disease mutations on the structure and interactions of the parkin ubiquitin-like domain.

Biochemistry 2011 Apr 9;50(13):2603-10. Epub 2011 Mar 9.

Department of Biochemistry, The University of Western Ontario, London, Ontario, Canada N6A 5C1.

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April 2011

Identification of a dimeric intermediate in the unfolding pathway for the calcium-binding protein S100B.

J Mol Biol 2008 Oct 6;382(4):1075-88. Epub 2008 Aug 6.

Department of Biochemistry, The University of Western Ontario, London, Ontario, Canada N6A 5C1.

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October 2008

Ubiquitin manipulation by an E2 conjugating enzyme using a novel covalent intermediate.

J Biol Chem 2005 Sep 12;280(36):31732-8. Epub 2005 Jul 12.

Department of Biochemistry, The University of Western Ontario, London, Ontario N6A 5C1, Canada.

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September 2005

Interaction between ErbB-1 and ErbB-2 transmembrane domains in bilayer membranes.

FEBS Lett 2002 May;519(1-3):103-7

Department of Biochemistry, University of Western Ontario, London, ON, Canada.

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May 2002

Evidence of a tendency to self-association of the transmembrane domain of ErbB-2 in fluid phospholipid bilayers.

Biochemistry 2002 Feb;41(7):2341-52

Department of Biochemistry, University of Western Ontario, London, Ontario, Canada N6A 5C1.

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February 2002