Publications by authors named "Kathryn Maitland"

100Publications

Transfusion Timing and Volume in African Children with Severe Anemia. Reply.

N Engl J Med 2019 10;381(17):1687-1688

Medical Research Council Clinical Trials Unit at University College London, London, United Kingdom.

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http://dx.doi.org/10.1056/NEJMc1911668DOI Listing
October 2019

Informing thresholds for paediatric transfusion in Africa: the need for a trial.

Wellcome Open Res 2019 12;4:27. Epub 2019 Aug 12.

Department of Medicine, Imperial College London, London, W2 1PG, UK.

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http://dx.doi.org/10.12688/wellcomeopenres.15003.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784792PMC
August 2019

Secondary re-analysis of the FEAST trial.

Lancet Respir Med 2019 10;7(10):e29

Medical Research Council Clinical Trials Unit at University College London, London, UK.

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http://dx.doi.org/10.1016/S2213-2600(19)30272-3DOI Listing
October 2019

Transfusion Volume for Children with Severe Anemia in Africa.

N Engl J Med 2019 08;381(5):420-431

From the Department of Medicine (K.M., T.N.W.) and Nutrition Research Section (G.F.), Imperial College London, and the Medical Research Council Clinical Trials Unit at University College London (E.C.G., D.M.G., A.S.W.), London, the School of Medicine, Dentistry, and Biomedical Science, Queen's University, Belfast (N.K.), the Liverpool School of Tropical Medicine and Hygiene, Liverpool (I.B.), the Department of Pediatrics, University Hospital of Wales, Cardiff (J.A.E.), and the Centre for Health Economics, University of York, York (P.S.G.) - all in the United Kingdom; Busitema University Faculty of Health Sciences, Mbale Campus, Mbale Regional Referral Hospital (P.O.-O., J.N., C.N.), and the Mbale Blood Transfusion Services (B.W.), Mbale, the Department of Pediatrics, Makerere University and Mulago Hospital (S.K., R.O.O., J.K.), and the Uganda Blood Transfusion Services, National Blood Transfusion Services (D.K.B.), Kampala, and Soroti Regional Referral Hospital, Soroti (F.A., C.E., M.N.) - all in Uganda; the Kenya Medical Research Institute-Wellcome Trust Research Program, Kilifi (K.M., A.M., S.U., T.N.W.); and the College of Medicine and the Malawi-Liverpool-Wellcome Trust Clinical Research Program (G.C., M.M., N.K.) and the Malawi Blood Transfusion Services (B.M.) - all in Blantyre, Malawi.

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http://dx.doi.org/10.1056/NEJMoa1900100DOI Listing
August 2019

Immediate Transfusion in African Children with Uncomplicated Severe Anemia.

N Engl J Med 2019 08;381(5):407-419

From the Department of Pediatrics (K.M., T.N.W.) and Nutrition Research Section (G.F.), Imperial College London, and the Medical Research Council Clinical Trials Unit at University College London (E.C.G., D.M.G., A.S.W.), London, the Centre for Health Economics, University of York, York (P.S.G.), the School of Medicine, Dentistry, and Biomedical Science, Queen's University, Belfast (N.K.), Liverpool School of Tropical Medicine and Hygiene, Liverpool (I.B.), and the Department of Pediatrics, University Hospital of Wales, Cardiff (J.A.E.) - all in the United Kingdom; the Department of Pediatrics, Makerere University and Mulago Hospital (S.K., R.O.O., E.N.), and the Uganda Blood Transfusion Services (BTS), National BTS (D.K.B.), Kampala, Busitema University Faculty of Health Sciences, Mbale Campus and Mbale Regional Referral Hospital (P.O.-O., J.N., C.N.), and Mbale BTS (B.W.), Mbale, and the Soroti Regional Referral Hospital, Soroti (C.E., F.A., M.N.) - all in Uganda; the College of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program (M.M., G.C.). and Malawi BTS (B.M.), Blantyre, Malawi; and the Kenya Medical Research Institute-Wellcome Trust Research Program, Kilifi, Kenya (K.M., A.M. S.U., T.N.W.).

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http://dx.doi.org/10.1056/NEJMoa1900105DOI Listing
August 2019

Healthcare-provider perceptions of barriers to oxygen therapy for paediatric patients in three government-funded eastern Ugandan hospitals; a qualitative study.

BMC Health Serv Res 2019 May 24;19(1):335. Epub 2019 May 24.

Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Faculty of Medicine, Imperial College, London, W2 1PG, UK.

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http://dx.doi.org/10.1186/s12913-019-4129-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534847PMC
May 2019

Assessment of Myocardial Function in Kenyan Children With Severe, Acute Malnutrition: The Cardiac Physiology in Malnutrition (CAPMAL) Study.

JAMA Netw Open 2019 03 1;2(3):e191054. Epub 2019 Mar 1.

Kenya Medical Research Institute Wellcome Trust Research Programme, Centre for Geographic Medicine Research-Coast, Kilifi, Kenya.

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http://dx.doi.org/10.1001/jamanetworkopen.2019.1054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6583281PMC
March 2019

Fluid resuscitation with 0.9% saline alters haemostasis in an ovine model of endotoxemic shock.

Thromb Res 2019 Apr 12;176:39-45. Epub 2019 Feb 12.

Critical Care Research Group, Prince Charles Hospital, Brisbane, Australia; University of Queensland, Brisbane, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2019.02.015DOI Listing
April 2019

Mortality after inpatient treatment for diarrhea in children: a cohort study.

BMC Med 2019 01 28;17(1):20. Epub 2019 Jan 28.

KEMRI/Wellcome Trust Research Programme, Centre for Geographic Medicine Research - Coast, PO Box 230, Kilifi, 80108, Kenya.

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http://dx.doi.org/10.1186/s12916-019-1258-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348640PMC
January 2019

Emergency fluid bolus therapy studies: first do no harm.

Authors:
Kathryn Maitland

Arch Dis Child 2019 05 28;104(5):409-410. Epub 2018 Sep 28.

Department of Paediatrics, Faculty of Medicine, Imperial College London, London, UK.

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http://adc.bmj.com/lookup/doi/10.1136/archdischild-2018-3158
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http://dx.doi.org/10.1136/archdischild-2018-315885DOI Listing
May 2019

Implications for paediatric shock management in resource-limited settings: a perspective from the FEAST trial.

Crit Care 2018 May 4;22(1):119. Epub 2018 May 4.

Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Faculty of Medicine, Imperial College, London, W2 1PG, UK.

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https://ccforum.biomedcentral.com/articles/10.1186/s13054-01
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http://dx.doi.org/10.1186/s13054-018-1966-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936024PMC
May 2018

Population Turnover in Remote Oceania Shortly after Initial Settlement.

Curr Biol 2018 04 28;28(7):1157-1165.e7. Epub 2018 Feb 28.

Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Howard Hughes Medical Institute, Boston, MA 02115, USA; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Max Planck-Harvard Research Center for the Archaeoscience of the Ancient Mediterranean, Cambridge, MA 02138, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2018.02.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882562PMC
April 2018

Oral rehydration of malnourished children with diarrhoea and dehydration: A systematic review.

Wellcome Open Res 2017 27;2:66. Epub 2017 Oct 27.

Department of Paediatrics, Faculty of Medicine, Imperial College, London, W2 1PG, UK.

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http://dx.doi.org/10.12688/wellcomeopenres.12357.3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657219PMC
October 2017

Intravenous rehydration of malnourished children with acute gastroenteritis and severe dehydration: A systematic review.

Wellcome Open Res 2017 18;2:65. Epub 2017 Aug 18.

Department of Paediatrics, Faculty of Medicine, Imperial College, London, W2 1PG, UK.

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http://dx.doi.org/10.12688/wellcomeopenres.12346.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590082PMC
August 2017

Enhanced Prophylaxis plus Antiretroviral Therapy for Advanced HIV Infection in Africa.

N Engl J Med 2017 07;377(3):233-245

From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.

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http://www.nejm.org/doi/10.1056/NEJMoa1615822
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http://dx.doi.org/10.1056/NEJMoa1615822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603269PMC
July 2017

Severe Malaria in African Children - The Need for Continuing Investment.

Authors:
Kathryn Maitland

N Engl J Med 2016 Dec;375(25):2416-2417

From the Wellcome Centre for Clinical Tropical Medicine, Imperial College, London.

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http://dx.doi.org/10.1056/NEJMp1613528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858851PMC
December 2016

Pediatric blood transfusion practices at a regional referral hospital in Kenya.

Transfusion 2016 11 9;56(11):2732-2738. Epub 2016 Sep 9.

Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute/Wellcome Trust Research Programme, Kilifi, Kenya.

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http://doi.wiley.com/10.1111/trf.13774
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http://dx.doi.org/10.1111/trf.13774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111588PMC
November 2016

Spleen volume and clinical disease manifestations of severe Plasmodium falciparum malaria in African children.

Trans R Soc Trop Med Hyg 2014 May 16;108(5):283-9. Epub 2014 Mar 16.

Division of Global Health, Department of Emergency Medicine, Yale University School of Medicine, 464 Congress Ave, Suite 260 New Haven, CT 06519, USA.

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http://dx.doi.org/10.1093/trstmh/tru040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693319PMC
May 2014

New diagnostics for common childhood infections.

Authors:
Kathryn Maitland

N Engl J Med 2014 Feb;370(9):875-7

From the Wellcome Trust Centre for Clinical Tropical Medicine, Faculty of Medicine, Imperial College, London; and the Kenya Medical Research Institute Wellcome Trust Research Programme, Kilifi, Kenya.

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http://dx.doi.org/10.1056/NEJMe1316036DOI Listing
February 2014

Authors' reply to Southall.

BMJ 2014 Feb 19;348:g1619. Epub 2014 Feb 19.

Department of Paediatrics, Mulago Hospital, Makerere University, Kampala, Uganda.

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http://dx.doi.org/10.1136/bmj.g1619DOI Listing
February 2014

Invasive bacterial co-infection in African children with Plasmodium falciparum malaria: a systematic review.

BMC Med 2014 Feb 19;12:31. Epub 2014 Feb 19.

Department of Paediatrics, Faculty of Medicine, Imperial College, Wellcome Trust Centre for Clinical Tropical Medicine, St Mary's Campus Norfolk Place, London W2 1PG, UK.

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http://dx.doi.org/10.1186/1741-7015-12-31DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928319PMC
February 2014

Strategies for efficient computation of the expected value of partial perfect information.

Med Decis Making 2014 04 21;34(3):327-42. Epub 2014 Jan 21.

School of Social and Community Medicine, University of Bristol, Bristol, UK (JM, AEA, MP, NJW).

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http://dx.doi.org/10.1177/0272989X13514774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948652PMC
April 2014

Management of severe malaria: results from recent trials.

Adv Exp Med Biol 2013 ;764:241-50

Mbale Regional Referral Hospital, Mbale, Uganda.

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http://dx.doi.org/10.1007/978-1-4614-4726-9_20DOI Listing
June 2013

Diagnostic performance of visible severe wasting for identifying severe acute malnutrition in children admitted to hospital in Kenya.

Bull World Health Organ 2011 Dec 19;89(12):900-6. Epub 2011 Oct 19.

KEMRI/Wellcome Trust Research Programme, Centre for Geographic Medical Research Coast, Kilifi, Kenya.

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http://dx.doi.org/10.2471/BLT.11.091280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260901PMC
December 2011

Dosing regimens of oral ciprofloxacin for children with severe malnutrition: a population pharmacokinetic study with Monte Carlo simulation.

J Antimicrob Chemother 2011 Oct 10;66(10):2336-45. Epub 2011 Aug 10.

KEMRI-Wellcome Trust Research Programme, Centre for Geographic Medicine Research (Coast), PO Box 230, 80108 Kilifi, Kenya.

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http://dx.doi.org/10.1093/jac/dkr314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172043PMC
October 2011

Imaging in severe malaria.

Authors:
Kathryn Maitland

Pediatr Crit Care Med 2011 Mar;12(2):237-8

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/PCC.0b013e3181e8b5f4DOI Listing
March 2011

Mortality after fluid bolus in African children with severe infection.

N Engl J Med 2011 Jun 26;364(26):2483-95. Epub 2011 May 26.

Kilifi Clinical Trials Facility, Kenya Medical Research Institute (KEMRI)-Wellcome Trust Research Programme, Kilifi, Kenya.

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http://dx.doi.org/10.1056/NEJMoa1101549DOI Listing
June 2011

Use of deferred consent for severely ill children in a multi-centre phase III trial.

Trials 2011 Mar 31;12:90. Epub 2011 Mar 31.

Kemri-Wellcome Centre for Geographic Medicine, Coast, Kenya.

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http://dx.doi.org/10.1186/1745-6215-12-90DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077324PMC
March 2011

Determination of ciprofloxacin in human plasma using high-performance liquid chromatography coupled with fluorescence detection: application to a population pharmacokinetics study in children with severe malnutrition.

J Chromatogr B Analyt Technol Biomed Life Sci 2011 Jan 4;879(2):146-52. Epub 2010 Dec 4.

Kenya Medical Research Institute (KEMRI)/Wellcome Trust Research Programme, Centre for Geographic Medicine Research (Coast), P.O. Box 230-80108, Kilifi, Kenya.

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http://dx.doi.org/10.1016/j.jchromb.2010.11.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025326PMC
January 2011

Hypoglycaemia in severe malaria, clinical associations and relationship to quinine dosage.

BMC Infect Dis 2010 Nov 22;10:334. Epub 2010 Nov 22.

Centre for Geographic Medicine Research, Kenya Medical Research Institute- Wellcome Trust Programme, PO Box 230, Kilifi, Kenya.

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http://dx.doi.org/10.1186/1471-2334-10-334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995467PMC
November 2010

Changing trends in blood transfusion in children and neonates admitted in Kilifi District Hospital, Kenya.

Malar J 2010 Oct 30;9:307. Epub 2010 Oct 30.

Kenya Medical Research Institute-Wellcome Trust Programme, PO Box 230, Kilifi, Kenya.

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http://dx.doi.org/10.1186/1475-2875-9-307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991344PMC
October 2010

Phase II trial of isotonic fluid resuscitation in Kenyan children with severe malnutrition and hypovolaemia.

BMC Pediatr 2010 Oct 6;10:71. Epub 2010 Oct 6.

KEMRI-Wellcome Trust Research Programme, Centre for Geographic Medicine Research-Coast, Kilifi, Kenya.

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http://bmcpediatr.biomedcentral.com/articles/10.1186/1471-24
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http://dx.doi.org/10.1186/1471-2431-10-71DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973932PMC
October 2010

Choice of fluids for resuscitation in children with severe infection and shock: systematic review.

BMJ 2010 Sep 2;341:c4416. Epub 2010 Sep 2.

Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute-Wellcome Trust Programme, PO Box 230, Kilifi, Kenya.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933356PMC
http://dx.doi.org/10.1136/bmj.c4416DOI Listing
September 2010

Phase II trial on the use of Dextran 70 or starch for supportive therapy in Kenyan children with severe malaria.

Crit Care Med 2010 Aug;38(8):1630-6

KEMRI-Wellcome Trust Research Programme, Centre for Geographic Medicine Research-Coast, Kilifi, Kenya.

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https://insights.ovid.com/crossref?an=00003246-201008000-000
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http://dx.doi.org/10.1097/CCM.0b013e3181e81165DOI Listing
August 2010

Antimicrobials in children admitted to hospital in malaria endemic areas.

Authors:
Kathryn Maitland

BMJ 2010 Apr 8;340:c1818. Epub 2010 Apr 8.

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http://dx.doi.org/10.1136/bmj.c1818DOI Listing
April 2010

The prognostic value of dipstick urinalysis in children admitted to hospital with severe malnutrition.

Arch Dis Child 2010 Jun 6;95(6):422-6. Epub 2010 Apr 6.

Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute, Kilifi, Kenya.

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http://dx.doi.org/10.1136/adc.2009.168211DOI Listing
June 2010

Cardiac function and hemodynamics in Kenyan children with severe malaria.

Crit Care Med 2010 Mar;38(3):940-5

Department of Infectious Diseases and Immunity, Hammersmith Campus, Imperial College, London, UK.

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http://dx.doi.org/10.1097/CCM.0b013e3181cd114aDOI Listing
March 2010

The quality of stored umbilical cord and adult-donated whole blood in Mombasa, Kenya.

Transfusion 2010 Mar 13;50(3):611-6. Epub 2009 Nov 13.

Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute/Wellcome Trust Research Programme, Kilifi, Kenya.

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http://dx.doi.org/10.1111/j.1537-2995.2009.02489.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948540PMC
March 2010

Bacterial contamination of pediatric whole blood transfusions in a Kenyan hospital.

Transfusion 2009 Dec 4;49(12):2594-8. Epub 2009 Aug 4.

Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute/Wellcome Trust Research Programme, Kilifi, Kenya.

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http://doi.wiley.com/10.1111/j.1537-2995.2009.02344.x
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http://dx.doi.org/10.1111/j.1537-2995.2009.02344.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939982PMC
December 2009