Publications by authors named "Kathryn L Evans"

53Publications

DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan.

Authors:
Jenny van Dongen Fiona A Hagenbeek Matthew Suderman Peter J Roetman Karen Sugden Andreas G Chiocchetti Khadeeja Ismail Rosa H Mulder Jonathan D Hafferty Mark J Adams Rosie M Walker Stewart W Morris Jari Lahti Leanne K Küpers Georgia Escaramis Silvia Alemany Marc Jan Bonder Mandy Meijer Hill F Ip Rick Jansen Bart M L Baselmans Priyanka Parmar Estelle Lowry Fabian Streit Lea Sirignano Tabea S Send Josef Frank Juulia Jylhävä Yunzhang Wang Pashupati Prasad Mishra Olivier F Colins David L Corcoran Richie Poulton Jonathan Mill Eilis Hannon Louise Arseneault Tellervo Korhonen Eero Vuoksimaa Janine F Felix Marian J Bakermans-Kranenburg Archie Campbell Darina Czamara Elisabeth Binder Eva Corpeleijn Juan R Gonzalez Regina Grazuleviciene Kristine B Gutzkow Jorunn Evandt Marina Vafeiadi Marieke Klein Dennis van der Meer Lannie Ligthart Cornelis Kluft Gareth E Davies Christian Hakulinen Liisa Keltikangas-Järvinen Barbara Franke Christine M Freitag Kerstin Konrad Amaia Hervas Aranzazu Fernández-Rivas Agnes Vetro Olli Raitakari Terho Lehtimäki Robert Vermeiren Timo Strandberg Katri Räikkönen Harold Snieder Stephanie H Witt Michael Deuschle Nancy L Pedersen Sara Hägg Jordi Sunyer Lude Franke Jaakko Kaprio Miina Ollikainen Terrie E Moffitt Henning Tiemeier Marinus H van IJzendoorn Caroline Relton Martine Vrijheid Sylvain Sebert Marjo-Riitta Jarvelin Avshalom Caspi Kathryn L Evans Andrew M McIntosh Meike Bartels Dorret I Boomsma

Mol Psychiatry 2021 Jan 8. Epub 2021 Jan 8.

Department of Biological Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

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January 2021

Identification of epigenome-wide DNA methylation differences between carriers of APOE ε4 and APOE ε2 alleles.

Authors:
Rosie M Walker Kadi Vaher Mairead L Bermingham Stewart W Morris Andrew D Bretherick Yanni Zeng Konrad Rawlik Carmen Amador Archie Campbell Chris S Haley Caroline Hayward David J Porteous Andrew M McIntosh Riccardo E Marioni Kathryn L Evans

Genome Med 2021 Jan 4;13(1). Epub 2021 Jan 4.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.

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January 2021

Structural brain correlates of serum and epigenetic markers of inflammation in major depressive disorder.

Authors:
Claire Green Xueyi Shen Anna J Stevenson Eleanor L S Conole Mathew A Harris Miruna C Barbu Emma L Hawkins Mark J Adams Robert F Hillary Stephen M Lawrie Kathryn L Evans Rosie M Walker Stewart W Morris David J Porteous Joanna M Wardlaw J Douglas Steele Gordon D Waiter Anca-Larisa Sandu Archie Campbell Riccardo E Marioni Simon R Cox Jonathan Cavanagh Andrew M McIntosh Heather C Whalley

Brain Behav Immun 2020 Nov 19. Epub 2020 Nov 19.

Division of Psychiatry, University of Edinburgh, Edinburgh, UK.

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November 2020

Birth weight associations with DNA methylation differences in an adult population.

Authors:
Rebecca A Madden Daniel L McCartney Rosie M Walker Robert F Hillary Mairead L Bermingham Konrad Rawlik Stewart W Morris Archie Campbell David J Porteous Ian J Deary Kathryn L Evans Jonathan Hafferty Andrew M McIntosh Riccardo E Marioni

Epigenetics 2020 Oct 20:1-14. Epub 2020 Oct 20.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh , Edinburgh, UK.

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October 2020

Author Correction: Bayesian reassessment of the epigenetic architecture of complex traits.

Authors:
Daniel Trejo Banos Daniel L McCartney Marion Patxot Lucas Anchieri Thomas Battram Colette Christiansen Ricardo Costeira Rosie M Walker Stewart W Morris Archie Campbell Qian Zhang David J Porteous Allan F McRae Naomi R Wray Peter M Visscher Chris S Haley Kathryn L Evans Ian J Deary Andrew M McIntosh Gibran Hemani Jordana T Bell Riccardo E Marioni Matthew R Robinson

Nat Commun 2020 Oct 9;11(1):5186. Epub 2020 Oct 9.

Institute of Science and Technology Austria, Klosterneuburg, Austria.

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October 2020

Epigenome-wide analyses identify DNA methylation signatures of dementia risk.

Authors:
Rosie M Walker Mairead L Bermingham Kadi Vaher Stewart W Morris Toni-Kim Clarke Andrew D Bretherick Yanni Zeng Carmen Amador Konrad Rawlik Kalyani Pandya Caroline Hayward Archie Campbell David J Porteous Andrew M McIntosh Riccardo E Marioni Kathryn L Evans

Alzheimers Dement (Amst) 2020 10;12(1):e12078. Epub 2020 Aug 10.

Centre for Genomic and Experimental Medicine Institute of Genetics and Molecular Medicine University of Edinburgh Edinburgh UK.

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August 2020

Epigenetic measures of ageing predict the prevalence and incidence of leading causes of death and disease burden.

Authors:
Robert F Hillary Anna J Stevenson Daniel L McCartney Archie Campbell Rosie M Walker David M Howard Craig W Ritchie Steve Horvath Caroline Hayward Andrew M McIntosh David J Porteous Ian J Deary Kathryn L Evans Riccardo E Marioni

Clin Epigenetics 2020 Jul 31;12(1):115. Epub 2020 Jul 31.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.

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July 2020

Characterisation of an inflammation-related epigenetic score and its association with cognitive ability.

Authors:
Anna J Stevenson Daniel L McCartney Robert F Hillary Archie Campbell Stewart W Morris Mairead L Bermingham Rosie M Walker Kathryn L Evans Thibaud S Boutin Caroline Hayward Allan F McRae Barry W McColl Tara L Spires-Jones Andrew M McIntosh Ian J Deary Riccardo E Marioni

Clin Epigenetics 2020 Jul 27;12(1):113. Epub 2020 Jul 27.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.

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July 2020

Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults.

Authors:
Robert F Hillary Daniel Trejo-Banos Athanasios Kousathanas Daniel L McCartney Sarah E Harris Anna J Stevenson Marion Patxot Sven Erik Ojavee Qian Zhang David C Liewald Craig W Ritchie Kathryn L Evans Elliot M Tucker-Drob Naomi R Wray Allan F McRae Peter M Visscher Ian J Deary Matthew R Robinson Riccardo E Marioni

Genome Med 2020 07 8;12(1):60. Epub 2020 Jul 8.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.

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July 2020

Epigenetic prediction of major depressive disorder.

Authors:
Miruna C Barbu Xueyi Shen Rosie M Walker David M Howard Kathryn L Evans Heather C Whalley David J Porteous Stewart W Morris Ian J Deary Yanni Zeng Riccardo E Marioni Toni-Kim Clarke Andrew M McIntosh

Mol Psychiatry 2020 Jun 10. Epub 2020 Jun 10.

Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.

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June 2020

Bayesian reassessment of the epigenetic architecture of complex traits.

Authors:
Daniel Trejo Banos Daniel L McCartney Marion Patxot Lucas Anchieri Thomas Battram Colette Christiansen Ricardo Costeira Rosie M Walker Stewart W Morris Archie Campbell Qian Zhang David J Porteous Allan F McRae Naomi R Wray Peter M Visscher Chris S Haley Kathryn L Evans Ian J Deary Andrew M McIntosh Gibran Hemani Jordana T Bell Riccardo E Marioni Matthew R Robinson

Nat Commun 2020 06 8;11(1):2865. Epub 2020 Jun 8.

Institute of Science and Technology Austria, Klosterneuburg, Austria.

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June 2020

Epigenome-wide association study and multi-tissue replication of individuals with alcohol use disorder: evidence for abnormal glucocorticoid signaling pathway gene regulation.

Authors:
Falk W Lohoff Arunima Roy Jeesun Jung Martha Longley Daniel B Rosoff Audrey Luo Emma O'Connell Jill L Sorcher Hui Sun Melanie Schwandt Colin A Hodgkinson David Goldman Reza Momenan Andrew M McIntosh Mark J Adams Rosie M Walker Kathryn L Evans David Porteous Alicia K Smith Jisoo Lee Christine Muench Katrin Charlet Toni-Kim Clarke Zachary A Kaminsky

Mol Psychiatry 2020 May 12. Epub 2020 May 12.

Royal's Institute of Mental Health Research, University of Ottawa, Ottawa, Canada.

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May 2020

DNA methylation in APOE: The relationship with Alzheimer's and with cardiovascular health.

Authors:
Jure Mur Daniel L McCartney Rosie M Walker Archie Campbell Mairead L Bermingham Stewart W Morris David J Porteous Andrew M McIntosh Ian J Deary Kathryn L Evans Riccardo E Marioni

Alzheimers Dement (N Y) 2020 27;6(1):e12026. Epub 2020 Apr 27.

Centre for Genomic and Experimental Medicine Institute of Genetics and Molecular Medicine University of Edinburgh Edinburgh UK.

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April 2020

DNA methylation outlier burden, health, and ageing in Generation Scotland and the Lothian Birth Cohorts of 1921 and 1936.

Authors:
Anne Seeboth Daniel L McCartney Yunzhang Wang Robert F Hillary Anna J Stevenson Rosie M Walker Archie Campbell Kathryn L Evans Andrew M McIntosh Sara Hägg Ian J Deary Riccardo E Marioni

Clin Epigenetics 2020 03 26;12(1):49. Epub 2020 Mar 26.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.

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March 2020

An epigenome-wide association study of sex-specific chronological ageing.

Authors:
Daniel L McCartney Futao Zhang Robert F Hillary Qian Zhang Anna J Stevenson Rosie M Walker Mairead L Bermingham Thibaud Boutin Stewart W Morris Archie Campbell Alison D Murray Heather C Whalley David J Porteous Caroline Hayward Kathryn L Evans Tamir Chandra Ian J Deary Andrew M McIntosh Jian Yang Peter M Visscher Allan F McRae Riccardo E Marioni

Genome Med 2019 12 31;12(1). Epub 2019 Dec 31.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland, UK.

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December 2019

An epigenetic predictor of death captures multi-modal measures of brain health.

Authors:
Robert F Hillary Anna J Stevenson Simon R Cox Daniel L McCartney Sarah E Harris Anne Seeboth Jon Higham Duncan Sproul Adele M Taylor Paul Redmond Janie Corley Alison Pattie Maria Del C Valdés Hernández Susana Muñoz-Maniega Mark E Bastin Joanna M Wardlaw Steve Horvath Craig W Ritchie Tara L Spires-Jones Andrew M McIntosh Kathryn L Evans Ian J Deary Riccardo E Marioni

Mol Psychiatry 2019 Dec 3. Epub 2019 Dec 3.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.

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December 2019

A meta-analysis of genome-wide association studies of epigenetic age acceleration.

Authors:
Jude Gibson Tom C Russ Toni-Kim Clarke David M Howard Robert F Hillary Kathryn L Evans Rosie M Walker Mairead L Bermingham Stewart W Morris Archie Campbell Caroline Hayward Alison D Murray David J Porteous Steve Horvath Ake T Lu Andrew M McIntosh Heather C Whalley Riccardo E Marioni

PLoS Genet 2019 11 18;15(11):e1008104. Epub 2019 Nov 18.

Centre for Cognitive Ageing & Cognitive Epidemiology, University of Edinburgh, Edinburgh, United Kingdom.

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November 2019

Epigenetic Age Acceleration and Cognitive Function in African American Adults in Midlife: The Atherosclerosis Risk in Communities Study.

Authors:
Jan Bressler Riccardo E Marioni Rosie M Walker Rui Xia Rebecca F Gottesman B Gwen Windham Megan L Grove Weihua Guan James S Pankow Kathryn L Evans Andrew M Mcintosh Ian J Deary Thomas H Mosley Eric Boerwinkle Myriam Fornage

J Gerontol A Biol Sci Med Sci 2020 02;75(3):473-480

Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, UK.

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February 2020

Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing.

Authors:
Qian Zhang Costanza L Vallerga Rosie M Walker Tian Lin Anjali K Henders Grant W Montgomery Ji He Dongsheng Fan Javed Fowdar Martin Kennedy Toni Pitcher John Pearson Glenda Halliday John B Kwok Ian Hickie Simon Lewis Tim Anderson Peter A Silburn George D Mellick Sarah E Harris Paul Redmond Alison D Murray David J Porteous Christopher S Haley Kathryn L Evans Andrew M McIntosh Jian Yang Jacob Gratten Riccardo E Marioni Naomi R Wray Ian J Deary Allan F McRae Peter M Visscher

Genome Med 2019 08 23;11(1):54. Epub 2019 Aug 23.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, 4072, Australia.

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August 2019

Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936.

Authors:
Robert F Hillary Daniel L McCartney Sarah E Harris Anna J Stevenson Anne Seeboth Qian Zhang David C Liewald Kathryn L Evans Craig W Ritchie Elliot M Tucker-Drob Naomi R Wray Allan F McRae Peter M Visscher Ian J Deary Riccardo E Marioni

Nat Commun 2019 07 18;10(1):3160. Epub 2019 Jul 18.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.

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July 2019

Correction: GWAS on family history of Alzheimer's disease.

Authors:
Riccardo E Marioni Sarah E Harris Qian Zhang Allan F McRae Saskia P Hagenaars W David Hill Gail Davies Craig W Ritchie Catharine R Gale John M Starr Alison M Goate David J Porteous Jian Yang Kathryn L Evans Ian J Deary Naomi R Wray Peter M Visscher

Transl Psychiatry 2019 Jun 6;9(1):161. Epub 2019 Jun 6.

Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.

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June 2019

Publisher Correction: Parent of origin genetic effects on methylation in humans are common and influence complex trait variation.

Authors:
Yanni Zeng Carmen Amador Charley Xia Riccardo Marioni Duncan Sproul Rosie M Walker Stewart W Morris Andrew Bretherick Oriol Canela-Xandri Thibaud S Boutin David W Clark Archie Campbell Konrad Rawlik Caroline Hayward Reka Nagy Albert Tenesa David J Porteous James F Wilson Ian J Deary Kathryn L Evans Andrew M McIntosh Pau Navarro Chris S Haley

Nat Commun 2019 May 1;10(1):2069. Epub 2019 May 1.

MRC Human Genetic Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.

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May 2019

Assessment of dried blood spots for DNA methylation profiling.

Authors:
Rosie M Walker Louise MacGillivray Sarah McCafferty Nicola Wrobel Lee Murphy Shona M Kerr Stewart W Morris Archie Campbell Andrew M McIntosh David J Porteous Kathryn L Evans

Wellcome Open Res 2019 6;4:44. Epub 2019 Mar 6.

Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Midlothian, EH4 2XU, UK.

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March 2019

Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPD.

Authors:
Mairead L Bermingham Rosie M Walker Riccardo E Marioni Stewart W Morris Konrad Rawlik Yanni Zeng Archie Campbell Paul Redmond Heather C Whalley Mark J Adams Caroline Hayward Ian J Deary David J Porteous Andrew M McIntosh Kathryn L Evans

EBioMedicine 2019 May 29;43:576-586. Epub 2019 Mar 29.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.

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May 2019

Parent of origin genetic effects on methylation in humans are common and influence complex trait variation.

Authors:
Yanni Zeng Carmen Amador Charley Xia Riccardo Marioni Duncan Sproul Rosie M Walker Stewart W Morris Andrew Bretherick Oriol Canela-Xandri Thibaud S Boutin David W Clark Archie Campbell Konrad Rawlik Caroline Hayward Reka Nagy Albert Tenesa David J Porteous James F Wilson Ian J Deary Kathryn L Evans Andrew M McIntosh Pau Navarro Chris S Haley

Nat Commun 2019 03 27;10(1):1383. Epub 2019 Mar 27.

MRC Human Genetic Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.

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March 2019

An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort.

Authors:
Olivia K L Hamilton Qian Zhang Allan F McRae Rosie M Walker Stewart W Morris Paul Redmond Archie Campbell Alison D Murray David J Porteous Kathryn L Evans Andrew M McIntosh Ian J Deary Riccardo E Marioni

Int J Obes (Lond) 2019 09 6;43(9):1795-1802. Epub 2019 Mar 6.

Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.

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September 2019

Epigenetic signatures of starting and stopping smoking.

Authors:
Daniel L McCartney Anna J Stevenson Robert F Hillary Rosie M Walker Mairead L Bermingham Stewart W Morris Toni-Kim Clarke Archie Campbell Alison D Murray Heather C Whalley David J Porteous Peter M Visscher Andrew M McIntosh Kathryn L Evans Ian J Deary Riccardo E Marioni

EBioMedicine 2018 Nov 30;37:214-220. Epub 2018 Oct 30.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland, United Kingdom; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, Scotland, United Kingdom. Electronic address:

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November 2018

Epigenetic prediction of complex traits and death.

Authors:
Daniel L McCartney Robert F Hillary Anna J Stevenson Stuart J Ritchie Rosie M Walker Qian Zhang Stewart W Morris Mairead L Bermingham Archie Campbell Alison D Murray Heather C Whalley Catharine R Gale David J Porteous Chris S Haley Allan F McRae Naomi R Wray Peter M Visscher Andrew M McIntosh Kathryn L Evans Ian J Deary Riccardo E Marioni

Genome Biol 2018 09 27;19(1):136. Epub 2018 Sep 27.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.

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September 2018

DISC1 regulates N-methyl-D-aspartate receptor dynamics: abnormalities induced by a Disc1 mutation modelling a translocation linked to major mental illness.

Authors:
Elise L V Malavasi Kyriakos D Economides Ellen Grünewald Paraskevi Makedonopoulou Philippe Gautier Shaun Mackie Laura C Murphy Hannah Murdoch Darragh Crummie Fumiaki Ogawa Daniel L McCartney Shane T O'Sullivan Karen Burr Helen S Torrance Jonathan Phillips Marion Bonneau Susan M Anderson Paul Perry Matthew Pearson Costas Constantinides Hazel Davidson-Smith Mostafa Kabiri Barbara Duff Mandy Johnstone H Greg Polites Stephen M Lawrie Douglas H Blackwood Colin A Semple Kathryn L Evans Michel Didier Siddharthan Chandran Andrew M McIntosh David J Price Miles D Houslay David J Porteous J Kirsty Millar

Transl Psychiatry 2018 09 6;8(1):184. Epub 2018 Sep 6.

Centre for Genomic and Experimental Medicine, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK.

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September 2018

Investigating the relationship between DNA methylation age acceleration and risk factors for Alzheimer's disease.

Authors:
Daniel L McCartney Anna J Stevenson Rosie M Walker Jude Gibson Stewart W Morris Archie Campbell Alison D Murray Heather C Whalley David J Porteous Andrew M McIntosh Kathryn L Evans Ian J Deary Riccardo E Marioni

Alzheimers Dement (Amst) 2018 21;10:429-437. Epub 2018 Jun 21.

Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.

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June 2018

DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies.

Authors:
Olivera Story Jovanova Ivana Nedeljkovic Derek Spieler Rosie M Walker Chunyu Liu Michelle Luciano Jan Bressler Jennifer Brody Amanda J Drake Kathryn L Evans Rahul Gondalia Sonja Kunze Brigitte Kuhnel Jari Lahti Rozenn N Lemaitre Riccardo E Marioni Brenton Swenson Jayandra Jung Himali Hongsheng Wu Yun Li Allan F McRae Tom C Russ James Stewart Zhiying Wang Guosheng Zhang Karl-Heinz Ladwig Andre G Uitterlinden Xiuqing Guo Annette Peters Katri Räikkönen John M Starr Melanie Waldenberger Naomi R Wray Eric A Whitsel Nona Sotoodehnia Sudha Seshadri David J Porteous Joyce van Meurs Thomas H Mosley Andrew M McIntosh Michael M Mendelson Daniel Levy Lifang Hou Johan G Eriksson Myriam Fornage Ian J Deary Andrea Baccarelli Henning Tiemeier Najaf Amin

JAMA Psychiatry 2018 09;75(9):949-959

Department of Epidemiology, Erasmus MC-University Medical Center Rotterdam, Rotterdam, the Netherlands.

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September 2018

DNA sequence-level analyses reveal potential phenotypic modifiers in a large family with psychiatric disorders.

Authors:
Niamh M Ryan Jayon Lihm Melissa Kramer Shane McCarthy Stewart W Morris Aleix Arnau-Soler Gail Davies Barbara Duff Elena Ghiban Caroline Hayward Ian J Deary Douglas H R Blackwood Stephen M Lawrie Andrew M McIntosh Kathryn L Evans David J Porteous W Richard McCombie Pippa A Thomson

Mol Psychiatry 2018 12 7;23(12):2254-2265. Epub 2018 Jun 7.

Centre for Genomic and Experimental Medicine, MRC Institute of Genetic and Molecular Medicine, University of Edinburgh, Edinburgh, UK.

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December 2018

GWAS on family history of Alzheimer's disease.

Authors:
Riccardo E Marioni Sarah E Harris Qian Zhang Allan F McRae Saskia P Hagenaars W David Hill Gail Davies Craig W Ritchie Catharine R Gale John M Starr Alison M Goate David J Porteous Jian Yang Kathryn L Evans Ian J Deary Naomi R Wray Peter M Visscher

Transl Psychiatry 2018 05 18;8(1):99. Epub 2018 May 18.

Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.

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May 2018

Altered DNA methylation associated with a translocation linked to major mental illness.

Authors:
Daniel L McCartney Rosie M Walker Stewart W Morris Susan M Anderson Barbara J Duff Riccardo E Marioni J Kirsty Millar Shane E McCarthy Niamh M Ryan Stephen M Lawrie Andrew R Watson Douglas H R Blackwood Pippa A Thomson Andrew M McIntosh W Richard McCombie David J Porteous Kathryn L Evans

NPJ Schizophr 2018 Mar 19;4(1). Epub 2018 Mar 19.

Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, University of Edinburgh, Crewe Road, Edinburgh, EH4 2XU, UK.

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March 2018

Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank.

Authors:
David M Howard Lynsey S Hall Jonathan D Hafferty Yanni Zeng Mark J Adams Toni-Kim Clarke David J Porteous Reka Nagy Caroline Hayward Blair H Smith Alison D Murray Niamh M Ryan Kathryn L Evans Chris S Haley Ian J Deary Pippa A Thomson Andrew M McIntosh

Transl Psychiatry 2017 11 30;7(11):1263. Epub 2017 Nov 30.

Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.

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November 2017

Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density.

Authors:
Nerea Alonso Karol Estrada Omar M E Albagha Lizbeth Herrera Sjur Reppe Ole K Olstad Kaare M Gautvik Niamh M Ryan Kathryn L Evans Carrie M Nielson Yi-Hsiang Hsu Douglas P Kiel George Markozannes Evangelia E Ntzani Evangelos Evangelou Bjarke Feenstra Xueping Liu Mads Melbye Laura Masi Maria Luisa Brandi Philip Riches Anna Daroszewska José Manuel Olmos Carmen Valero Jesús Castillo José A Riancho Lise B Husted Bente L Langdahl Matthew A Brown Emma L Duncan Stephen Kaptoge Kay-Tee Khaw Ricardo Usategui-Martín Javier Del Pino-Montes Rogelio González-Sarmiento Joshua R Lewis Richard L Prince Patrizia D'Amelio Natalia García-Giralt Xavier Nogués Simona Mencej-Bedrac Janja Marc Orit Wolstein John A Eisman Ling Oei Carolina Medina-Gómez Katharina E Schraut Pau Navarro James F Wilson Gail Davies John Starr Ian Deary Toshiko Tanaka Luigi Ferrucci Fernando Gianfrancesco Luigi Gennari Gavin Lucas Roberto Elosua André G Uitterlinden Fernando Rivadeneira Stuart H Ralston

Ann Rheum Dis 2018 03 23;77(3):378-385. Epub 2017 Nov 23.

Rheumatology and Bone Disease Unit, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.

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March 2018

Haplotype-based association analysis of general cognitive ability in Generation Scotland, the English Longitudinal Study of Ageing, and UK Biobank.

Authors:
David M Howard Mark J Adams Toni-Kim Clarke Eleanor M Wigmore Yanni Zeng Saskia P Hagenaars Donald M Lyall Pippa A Thomson Kathryn L Evans David J Porteous Reka Nagy Caroline Hayward Chris S Haley Blair H Smith Alison D Murray G David Batty Ian J Deary Andrew M McIntosh

Wellcome Open Res 2017 10;2:61. Epub 2017 Aug 10.

Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.

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August 2017

Identification of polymorphic and off-target probe binding sites on the Illumina Infinium MethylationEPIC BeadChip.

Authors:
Daniel L McCartney Rosie M Walker Stewart W Morris Andrew M McIntosh David J Porteous Kathryn L Evans

Genom Data 2016 Sep 26;9:22-4. Epub 2016 May 26.

Medical Genetics Section, Centre for Genomic and Experimental Medicine, MRC Institute of Genetics and Molecular Medicine, Western General Hospital, The University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, UK; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, The University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, UK.

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September 2016

SuRFing the genomics wave: an R package for prioritising SNPs by functionality.

Authors:
Niamh M Ryan Stewart W Morris David J Porteous Martin S Taylor Kathryn L Evans

Genome Med 2014 14;6(10):79. Epub 2014 Oct 14.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, The University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU UK ; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ UK.

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November 2014

Impact of a microRNA MIR137 susceptibility variant on brain function in people at high genetic risk of schizophrenia or bipolar disorder.

Authors:
Heather C Whalley Martina Papmeyer Liana Romaniuk Emma Sprooten Eve C Johnstone Jeremy Hall Stephen M Lawrie Kathryn L Evans Hilary P Blumberg Jessika E Sussmann Andrew M McIntosh

Neuropsychopharmacology 2012 Nov 1;37(12):2720-9. Epub 2012 Aug 1.

Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.

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November 2012

Genetic variation in Hyperpolarization-activated cyclic nucleotide-gated channels and its relationship with neuroticism, cognition and risk of depression.

Authors:
Andrew M McIntosh Arthur A Simen Kathryn L Evans Jeremy Hall Donald J Macintyre Douglas Blackwood Andrew D Morris Blair H Smith Anna Dominiczak David Porteous Hb Ian J Deary Pippa A Thomson

Front Genet 2012 2;3:116. Epub 2012 Jul 2.

Division of Psychiatry, Royal Edinburgh Hospital, University of Edinburgh, Edinburgh, UK.

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October 2012

The DISC1 promoter: characterization and regulation by FOXP2.

Authors:
Rosie M Walker Alison E Hill Alice C Newman Gillian Hamilton Helen S Torrance Susan M Anderson Fumiaki Ogawa Pelagia Derizioti Jérôme Nicod Sonja C Vernes Simon E Fisher Pippa A Thomson David J Porteous Kathryn L Evans

Hum Mol Genet 2012 Jul 20;21(13):2862-72. Epub 2012 Mar 20.

Medical Genetics Section, Molecular Medicine Centre, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.

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July 2012

Alzheimer's disease risk factor complement receptor 1 is associated with depression.

Authors:
Gillian Hamilton Kathryn L Evans Donald J Macintyre Ian J Deary Anna Dominiczak Blair H Smith Andrew D Morris David J Porteous Pippa A Thomson

Neurosci Lett 2012 Feb 8;510(1):6-9. Epub 2012 Jan 8.

Medical Genetics, Molecular Medicine Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road South, Edinburgh, UK.

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February 2012

Association analysis of Neuregulin 1 candidate regions in schizophrenia and bipolar disorder.

Authors:
Rosie M Walker Andrea Christoforou Pippa A Thomson Kevin A McGhee Alan Maclean Thomas W Mühleisen Jana Strohmaier Vanessa Nieratschker Markus M Nöthen Marcella Rietschel Sven Cichon Stewart W Morris Omer Jilani David Stclair Douglas H Blackwood Walter J Muir David J Porteous Kathryn L Evans

Neurosci Lett 2010 Jun 7;478(1):9-13. Epub 2010 May 7.

Medical Genetics Section, Centre for Molecular Medicine and Institute of Genetics and Molecular Medicine, Molecular Medicine Centre, Western General Hospital, University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, UK.

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June 2010

A case-control association study and family-based expression analysis of the bipolar disorder candidate gene PI4K2B.

Authors:
Lorna M Houlihan Andrea Christoforou Margaret I Arbuckle Helen S Torrance Susan M Anderson Walter J Muir David J Porteous Douglas H Blackwood Kathryn L Evans

J Psychiatr Res 2009 Dec 17;43(16):1272-7. Epub 2009 Jun 17.

Medical Genetics Section, Molecular Medicine Centre, The University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK.

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December 2009

Are some genetic risk factors common to schizophrenia, bipolar disorder and depression? Evidence from DISC1, GRIK4 and NRG1.

Authors:
Douglas H R Blackwood Ben J Pickard Pippa A Thomson Kathryn L Evans David J Porteous Walter J Muir

Neurotox Res 2007 Jan;11(1):73-83

Division of Psychiatry, The University of Edinburgh, Royal Edinburgh Hospital, Edinburgh EH10 5HF, UK.

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January 2007

The PDE4B gene confers sex-specific protection against schizophrenia.

Authors:
Benjamin S Pickard Philippa A Thomson Andrea Christoforou Kathryn L Evans Stewart W Morris David J Porteous Douglas H R Blackwood Walter J Muir

Psychiatr Genet 2007 Jun;17(3):129-33

Medical Genetics Section, School of Clinical and Molecular Medicine, Molecular Medicine Centre, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.

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June 2007

A neuregulin 1 variant associated with abnormal cortical function and psychotic symptoms.

Authors:
Jeremy Hall Heather C Whalley Dominic E Job Ben J Baig Andrew M McIntosh Kathryn L Evans Pippa A Thomson David J Porteous David G Cunningham-Owens Eve C Johnstone Stephen M Lawrie

Nat Neurosci 2006 Dec 29;9(12):1477-8. Epub 2006 Oct 29.

Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Morningside Park, Edinburgh, EH10 5HF, UK.

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December 2006

Haplotype analysis and a novel allele-sharing method refines a chromosome 4p locus linked to bipolar affective disorder.

Authors:
Stephanie Le Hellard Andrew J Lee Sarah Underwood Pippa A Thomson Stewart W Morris Helen S Torrance Susan M Anderson Richard R Adams Pau Navarro Andrea Christoforou Lorna M Houlihan Sevilla Detera-Wadleigh Michael J Owen Philip Asherson Walter J Muir Douglas H R Blackwood Naomi R Wray David J Porteous Kathryn L Evans

Biol Psychiatry 2007 Mar 25;61(6):797-805. Epub 2006 Sep 25.

Medical Genetics Section, School of Clinical and Molecular Medicine, Molecular Medicine Centre, University of Edinburgh, Scotland, United Kingdom.

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March 2007

The DNA sequence of the human X chromosome.

Authors:
Mark T Ross Darren V Grafham Alison J Coffey Steven Scherer Kirsten McLay Donna Muzny Matthias Platzer Gareth R Howell Christine Burrows Christine P Bird Adam Frankish Frances L Lovell Kevin L Howe Jennifer L Ashurst Robert S Fulton Ralf Sudbrak Gaiping Wen Matthew C Jones Matthew E Hurles T Daniel Andrews Carol E Scott Stephen Searle Juliane Ramser Adam Whittaker Rebecca Deadman Nigel P Carter Sarah E Hunt Rui Chen Andrew Cree Preethi Gunaratne Paul Havlak Anne Hodgson Michael L Metzker Stephen Richards Graham Scott David Steffen Erica Sodergren David A Wheeler Kim C Worley Rachael Ainscough Kerrie D Ambrose M Ali Ansari-Lari Swaroop Aradhya Robert I S Ashwell Anne K Babbage Claire L Bagguley Andrea Ballabio Ruby Banerjee Gary E Barker Karen F Barlow Ian P Barrett Karen N Bates David M Beare Helen Beasley Oliver Beasley Alfred Beck Graeme Bethel Karin Blechschmidt Nicola Brady Sarah Bray-Allen Anne M Bridgeman Andrew J Brown Mary J Brown David Bonnin Elspeth A Bruford Christian Buhay Paula Burch Deborah Burford Joanne Burgess Wayne Burrill John Burton Jackie M Bye Carol Carder Laura Carrel Joseph Chako Joanne C Chapman Dean Chavez Ellson Chen Guan Chen Yuan Chen Zhijian Chen Craig Chinault Alfredo Ciccodicola Sue Y Clark Graham Clarke Chris M Clee Sheila Clegg Kerstin Clerc-Blankenburg Karen Clifford Vicky Cobley Charlotte G Cole Jen S Conquer Nicole Corby Richard E Connor Robert David Joy Davies Clay Davis John Davis Oliver Delgado Denise Deshazo Pawandeep Dhami Yan Ding Huyen Dinh Steve Dodsworth Heather Draper Shannon Dugan-Rocha Andrew Dunham Matthew Dunn K James Durbin Ireena Dutta Tamsin Eades Matthew Ellwood Alexandra Emery-Cohen Helen Errington Kathryn L Evans Louisa Faulkner Fiona Francis John Frankland Audrey E Fraser Petra Galgoczy James Gilbert Rachel Gill Gernot Glöckner Simon G Gregory Susan Gribble Coline Griffiths Russell Grocock Yanghong Gu Rhian Gwilliam Cerissa Hamilton Elizabeth A Hart Alicia Hawes Paul D Heath Katja Heitmann Steffen Hennig Judith Hernandez Bernd Hinzmann Sarah Ho Michael Hoffs Phillip J Howden Elizabeth J Huckle Jennifer Hume Paul J Hunt Adrienne R Hunt Judith Isherwood Leni Jacob David Johnson Sally Jones Pieter J de Jong Shirin S Joseph Stephen Keenan Susan Kelly Joanne K Kershaw Ziad Khan Petra Kioschis Sven Klages Andrew J Knights Anna Kosiura Christie Kovar-Smith Gavin K Laird Cordelia Langford Stephanie Lawlor Margaret Leversha Lora Lewis Wen Liu Christine Lloyd David M Lloyd Hermela Loulseged Jane E Loveland Jamieson D Lovell Ryan Lozado Jing Lu Rachael Lyne Jie Ma Manjula Maheshwari Lucy H Matthews Jennifer McDowall Stuart McLaren Amanda McMurray Patrick Meidl Thomas Meitinger Sarah Milne George Miner Shailesh L Mistry Margaret Morgan Sidney Morris Ines Müller James C Mullikin Ngoc Nguyen Gabriele Nordsiek Gerald Nyakatura Christopher N O'Dell Geoffery Okwuonu Sophie Palmer Richard Pandian David Parker Julia Parrish Shiran Pasternak Dina Patel Alex V Pearce Danita M Pearson Sarah E Pelan Lesette Perez Keith M Porter Yvonne Ramsey Kathrin Reichwald Susan Rhodes Kerry A Ridler David Schlessinger Mary G Schueler Harminder K Sehra Charles Shaw-Smith Hua Shen Elizabeth M Sheridan Ratna Shownkeen Carl D Skuce Michelle L Smith Elizabeth C Sotheran Helen E Steingruber Charles A Steward Roy Storey R Mark Swann David Swarbreck Paul E Tabor Stefan Taudien Tineace Taylor Brian Teague Karen Thomas Andrea Thorpe Kirsten Timms Alan Tracey Steve Trevanion Anthony C Tromans Michele d'Urso Daniel Verduzco Donna Villasana Lenee Waldron Melanie Wall Qiaoyan Wang James Warren Georgina L Warry Xuehong Wei Anthony West Siobhan L Whitehead Mathew N Whiteley Jane E Wilkinson David L Willey Gabrielle Williams Leanne Williams Angela Williamson Helen Williamson Laurens Wilming Rebecca L Woodmansey Paul W Wray Jennifer Yen Jingkun Zhang Jianling Zhou Huda Zoghbi Sara Zorilla David Buck Richard Reinhardt Annemarie Poustka André Rosenthal Hans Lehrach Alfons Meindl Patrick J Minx Ladeana W Hillier Huntington F Willard Richard K Wilson Robert H Waterston Catherine M Rice Mark Vaudin Alan Coulson David L Nelson George Weinstock John E Sulston Richard Durbin Tim Hubbard Richard A Gibbs Stephan Beck Jane Rogers David R Bentley

Nature 2005 Mar;434(7031):325-37

The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

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March 2005

Speeding disease gene discovery by sequence based candidate prioritization.

Authors:
Euan A Adie Richard R Adams Kathryn L Evans David J Porteous Ben S Pickard

BMC Bioinformatics 2005 Mar 14;6:55. Epub 2005 Mar 14.

Medical Genetics Section, Department of Medical Sciences, The University of Edinburgh, Edinburgh, UK.

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March 2005

SNP genotyping on pooled DNAs: comparison of genotyping technologies and a semi automated method for data storage and analysis.

Authors:
Stéphanie Le Hellard Stéphane J Ballereau Peter M Visscher Helen S Torrance Jeni Pinson Stewart W Morris Marian L Thomson Colin A M Semple Walter J Muir Douglas H R Blackwood David J Porteous Kathryn L Evans

Nucleic Acids Res 2002 Aug;30(15):e74

Medical Genetics Section, Molecular Medicine Centre, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK.

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August 2002

Computational comparison of human genomic sequence assemblies for a region of chromosome 4.

Authors:
Colin A M Semple Stewart W Morris David J Porteous Kathryn L Evans

Genome Res 2002 Mar;12(3):424-9

Medical Genetics Section, Department of Medical Sciences, The University of Edinburgh, Molecular Medicine Centre, Western General Hospital, Edinburgh EH4 2XU, Scotland, United Kingdom.

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March 2002