Publications by authors named "Kathryn Gilroy"

17Publications

Collaboration of MYC and RUNX2 in lymphoma simulates T-cell receptor signaling and attenuates p53 pathway activity.

J Cell Biochem 2019 10 30;120(10):18332-18345. Epub 2019 Jun 30.

Molecular Oncology Laboratory, Centre for Virus Research, Institute of Infection, Immunity, and Inflammation, University of Glasgow, Glasgow, United Kingdom.

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http://dx.doi.org/10.1002/jcb.29143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772115PMC
October 2019

A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma.

Cell 2019 04 4;177(3):572-586.e22. Epub 2019 Apr 4.

Department of Pharmacology, University of California, San Diego School of Medicine, La Jolla, CA, USA; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA; Moores Cancer Center, University of California, San Diego School of Medicine, La Jolla, CA, USA; Department of Medicine, University of California, San Diego School of Medicine, La Jolla, CA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674193027
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http://dx.doi.org/10.1016/j.cell.2019.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711371PMC
April 2019

RUNX-mediated growth arrest and senescence are attenuated by diverse mechanisms in cells expressing RUNX1 fusion oncoproteins.

J Cell Biochem 2018 03 20;119(3):2750-2762. Epub 2017 Nov 20.

Molecular Oncology Laboratory, Centre for Virus Research, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK.

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http://dx.doi.org/10.1002/jcb.26443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813226PMC
March 2018

The RUNX Genes as Conditional Oncogenes: Insights from Retroviral Targeting and Mouse Models.

Adv Exp Med Biol 2017 ;962:247-264

Molecular Oncology Laboratory, Centre for Virus Research, University of Glasgow, Bearsden, Glasgow, G61 1QH, UK.

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http://dx.doi.org/10.1007/978-981-10-3233-2_16DOI Listing
September 2017

Gamma-Retrovirus Integration Marks Cell Type-Specific Cancer Genes: A Novel Profiling Tool in Cancer Genomics.

PLoS One 2016 20;11(4):e0154070. Epub 2016 Apr 20.

MRC-University of Glasgow Centre for Virus Research, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0154070PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838236PMC
September 2016

Addiction to Runx1 is partially attenuated by loss of p53 in the Eµ-Myc lymphoma model.

Oncotarget 2016 Apr;7(17):22973-87

Molecular Oncology Laboratory, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK.

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http://dx.doi.org/10.18632/oncotarget.8554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029604PMC
April 2016

Frequent infection of human cancer xenografts with murine endogenous retroviruses in vivo.

Viruses 2015 Apr 17;7(4):2014-29. Epub 2015 Apr 17.

Molecular Oncology Laboratory, MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Garscube Estate, Bearsden Road, G61 1QH Glasgow, UK.

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http://dx.doi.org/10.3390/v7042014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411688PMC
April 2015

Insertional mutagenesis and deep profiling reveals gene hierarchies and a Myc/p53-dependent bottleneck in lymphomagenesis.

PLoS Genet 2014 Feb 27;10(2):e1004167. Epub 2014 Feb 27.

Centre for Virus Research, Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1004167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937229PMC
February 2014

The impact of the C-terminal domain on the interaction of human DNA topoisomerase II α and β with DNA.

PLoS One 2011 Feb 16;6(2):e14693. Epub 2011 Feb 16.

Institute for Cell and Molecular Biosciences, University of Newcastle Upon Tyne, Newcastle upon Tyne, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0014693PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040172PMC
February 2011

A simple, sensitive and selective quantum-dot-based western blot method for the simultaneous detection of multiple targets from cell lysates.

Anal Bioanal Chem 2010 Sep 27;398(1):547-54. Epub 2010 Jun 27.

Integrative and Systems Biology, Faculty of Biomedical and Life Sciences, University of Glasgow, University Avenue, Glasgow G12 8QQ, UK.

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http://link.springer.com/10.1007/s00216-010-3908-0
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http://dx.doi.org/10.1007/s00216-010-3908-0DOI Listing
September 2010

The impact of the human DNA topoisomerase II C-terminal domain on activity.

PLoS One 2008 Mar 12;3(3):e1754. Epub 2008 Mar 12.

Institute for Cell and Molecular Biosciences, The University of Newcastle upon Tyne, Newcastle Upon Tyne, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0001754PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2262138PMC
March 2008

Curcumin induces high levels of topoisomerase I- and II-DNA complexes in K562 leukemia cells.

J Nat Prod 2007 Dec 13;70(12):1884-8. Epub 2007 Dec 13.

Institute for Cell and Molecular Biosciences, The Medical School, Newcastle University, Newcastle-upon-Tyne, UK.

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http://dx.doi.org/10.1021/np070332iDOI Listing
December 2007

Differential selection of acridine resistance mutations in human DNA topoisomerase IIbeta is dependent on the acridine structure.

Mol Pharmacol 2007 Apr 5;71(4):1006-14. Epub 2007 Jan 5.

The Institute for Cell and Molecular Biosciences, The Medical School, Newcastle University, Framlington Place, Newcastle Upon Tyne, NE2 4HH, United Kingdom.

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http://dx.doi.org/10.1124/mol.106.032953DOI Listing
April 2007

mAMSA resistant human topoisomerase IIbeta mutation G465D has reduced ATP hydrolysis activity.

Nucleic Acids Res 2006 20;34(5):1597-607. Epub 2006 Mar 20.

The Institute for Cell and Molecular Biosciences, The University of Newcastle upon Tyne, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK.

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http://dx.doi.org/10.1093/nar/gkl057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1405819PMC
April 2006