Kathleen M Gillespie

Kathleen M Gillespie

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Kathleen M Gillespie

Kathleen M Gillespie

Publications by authors named "Kathleen M Gillespie"

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What Have Slow Progressors Taught Us About T1D-Mind the Gap!

Curr Diab Rep 2019 Sep 10;19(10):99. Epub 2019 Sep 10.

Diabetes and Metabolism, Bristol Medical School, University of Bristol, Level 2, Learning and Research, Southmead Hospital, Bristol, BS10 5NB, UK.

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http://dx.doi.org/10.1007/s11892-019-1219-1DOI Listing
September 2019

Identification of loci where DNA methylation potentially mediates genetic risk of type 1 diabetes.

J Autoimmun 2018 09 29;93:66-75. Epub 2018 Jun 29.

MRC Integrative Epidemiology Unit, Bristol Medical School (Population Health Sciences), University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S08968411183020
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http://dx.doi.org/10.1016/j.jaut.2018.06.005DOI Listing
September 2018

Biomarkers in Islet Cell Transplantation for Type 1 Diabetes.

Curr Diab Rep 2018 09 5;18(10):94. Epub 2018 Sep 5.

Diabetes and Metabolism, Bristol Medical School, University of Bristol, Level 2, Learning and Research, Southmead Hospital, Bristol, BS10 5NB, UK.

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http://dx.doi.org/10.1007/s11892-018-1059-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132734PMC
September 2018

What factors influence recruitment to a birth cohort of infants with Down's syndrome?

Arch Dis Child 2018 08 8;103(8):763-766. Epub 2018 Mar 8.

The NIHR Bristol Biomedical Research Centre, Nutrition Theme, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1136/archdischild-2017-314312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059035PMC
August 2018

Unravelling the Roles of Susceptibility Loci for Autoimmune Diseases in the Post-GWAS Era.

Genes (Basel) 2018 Jul 27;9(8). Epub 2018 Jul 27.

MRC Integrative Epidemiology Unit, Population Health Sciences, University of Bristol, Bristol BS8 2BN, UK.

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http://dx.doi.org/10.3390/genes9080377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115971PMC
July 2018

A novel LIPS assay for insulin autoantibodies.

Acta Diabetol 2018 Mar 5;55(3):263-270. Epub 2018 Jan 5.

Human Pathology Genomic Diagnostics Unit, Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.

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http://dx.doi.org/10.1007/s00592-017-1082-yDOI Listing
March 2018

Fluorescence In Situ Hybridization with Concomitant Immunofluorescence in Human Pancreas.

Methods Mol Biol 2016 ;1433:153-8

Diabetes and Metabolism Unit, School of Clinical Sciences, Southmead Hospital, University of Bristol, Bristol, UK.

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http://link.springer.com/10.1007/7651_2015_288
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http://dx.doi.org/10.1007/7651_2015_288DOI Listing
October 2017

Type 1 Diabetes High-Risk HLA Class II Determination by Polymerase Chain Reaction Sequence-Specific Primers.

Methods Mol Biol 2016 ;1433:13-20

Diabetes and Metabolism Unit, School of Clinical Sciences, Southmead Hospital, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1007/7651_2015_307DOI Listing
October 2017

Type 1 Diabetes: Current Perspectives.

Methods Mol Biol 2016 ;1433:1-9

Diabetes and Metabolism Unit, School of Clinical Sciences, Southmead Hospital, University of Bristol, Bristol, UK.

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http://link.springer.com/10.1007/7651_2015_289
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http://dx.doi.org/10.1007/7651_2015_289DOI Listing
October 2017

Histology of Type 1 Diabetes Pancreas.

Methods Mol Biol 2016 ;1433:105-17

Diabetes and Metabolism Unit, School of Clinical Sciences, Southmead Hospital, University of Bristol, Bristol, UK.

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http://link.springer.com/10.1007/7651_2015_287
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http://dx.doi.org/10.1007/7651_2015_287DOI Listing
October 2017

Germinal centre frequency is decreased in pancreatic lymph nodes from individuals with recent-onset type 1 diabetes.

Diabetologia 2017 07 17;60(7):1294-1303. Epub 2017 Feb 17.

Diabetes and Metabolism, Level 2 Learning and Research, University of Bristol, Southmead Hospital, Bristol, BS10 5NB, UK.

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http://dx.doi.org/10.1007/s00125-017-4221-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487689PMC
July 2017

Beta cell function and ongoing autoimmunity in long-standing, childhood onset type 1 diabetes.

Diabetologia 2016 12 3;59(12):2722-2726. Epub 2016 Sep 3.

Diabetes and Metabolism, School of Clinical Sciences, Southmead Hospital, Level 2 Learning and Research Building, Bristol, BS10 5NB, UK.

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http://dx.doi.org/10.1007/s00125-016-4087-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518060PMC
December 2016

Attenuated humoral responses in HLA-A*24-positive individuals at risk of type 1 diabetes.

Diabetologia 2015 Oct 30;58(10):2284-7. Epub 2015 Jul 30.

Diabetes and Metabolism, School of Clinical Sciences, University of Bristol, Level 2 Learning and Research Building, Southmead Hospital, Bristol, BS10 5NB, UK.

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http://dx.doi.org/10.1007/s00125-015-3702-9DOI Listing
October 2015

Reactivity to N-Terminally Truncated GAD65(96-585) Identifies GAD Autoantibodies That Are More Closely Associated With Diabetes Progression in Relatives of Patients With Type 1 Diabetes.

Diabetes 2015 Sep 22;64(9):3247-52. Epub 2015 May 22.

Institute of Diabetes Research, Helmholtz Zentrum München, and Forschergruppe Diabetes, Klinikum rechts der Isar, Technische Universität München, Neuherberg, Germany.

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http://dx.doi.org/10.2337/db14-1694DOI Listing
September 2015

Maternal microchimerism: friend or foe in type 1 diabetes?

Chimerism 2014 ;5(2):21-3

Diabetes and Metabolism Unit; School of Clinical Sciences; University of Bristol; Bristol, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199804PMC
http://dx.doi.org/10.4161/chim.29870DOI Listing
May 2015

Early onset of diabetes in the proband is the major determinant of risk in HLA DR3-DQ2/DR4-DQ8 siblings.

Diabetes 2014 Mar 7;63(3):1041-7. Epub 2013 Nov 7.

Diabetes and Metabolism, School of Clinical Sciences, University of Bristol, Bristol, U.K.

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http://dx.doi.org/10.2337/db13-0994DOI Listing
March 2014

Insulin-like growth factor binding protein-3 (IGFBP-3) plays a role in the anti-tumorigenic effects of 5-Aza-2'-deoxycytidine (AZA) in breast cancer cells.

Exp Cell Res 2013 Aug 26;319(14):2282-95. Epub 2013 Jun 26.

IGFs & Metabolic Endocrinology Group, University of Bristol, Learning & Research Building, Southmead Hospital, Bristol BS10 5NB, United Kingdom.

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http://dx.doi.org/10.1016/j.yexcr.2013.06.011DOI Listing
August 2013

Maternal microchimerism in muscle biopsies from children with juvenile dermatomyositis.

Rheumatology (Oxford) 2012 Jun 23;51(6):987-91. Epub 2012 Jan 23.

Learning and Research, University of Bristol, Southmead Hospital, Bristol BS10 5NB, UK.

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https://academic.oup.com/rheumatology/article-lookup/doi/10.
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http://dx.doi.org/10.1093/rheumatology/ker430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3354676PMC
June 2012

Rising incidence of type 1 diabetes is associated with altered immunophenotype at diagnosis.

Diabetes 2012 Mar 7;61(3):683-6. Epub 2012 Feb 7.

School of Clinical Sciences, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.2337/db11-0962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282823PMC
March 2012

Why are levels of maternal microchimerism higher in type 1 diabetes pancreas?

Chimerism 2010 Oct;1(2):45-50

Diabetes and Metabolism; Department of Clinical Science at North Bristol; University of Bristol; Bristol, UK.

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http://dx.doi.org/10.4161/chim.1.2.13891DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023622PMC
October 2010

Microchimerism: covert genetics?

Int J Mol Epidemiol Genet 2010 Sep 11;1(4):350-7. Epub 2010 Sep 11.

Diabetes and Metabolism, School of Clinical Sciences, University of Bristol UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076780PMC
September 2010

The genetic basis for type 1 diabetes.

Br Med Bull 2008 ;88(1):115-29

Medical School Unit, Southmead Hospital, Bristol BS105NB, UK.

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https://academic.oup.com/bmb/article-lookup/doi/10.1093/bmb/
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http://dx.doi.org/10.1093/bmb/ldn045DOI Listing
April 2009

Microchimerism in type 1 diabetes.

Curr Diab Rep 2009 Apr;9(2):125-9

University of Bristol, Southmead Hospital, Bristol BS10 5NB, UK.

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April 2009

Islet autoimmunity in children with Down's syndrome.

Diabetes 2006 Nov;55(11):3185-8

Medical School Unit, Southmead Hospital, Bristol BS10 5NB, UK.

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http://dx.doi.org/10.2337/db06-0856DOI Listing
November 2006

Type 1 diabetes: pathogenesis and prevention.

CMAJ 2006 Jul;175(2):165-70

Department of Clinical Science at North Bristol, University of Bristol, UK.

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http://dx.doi.org/10.1503/cmaj.060244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1489998PMC
July 2006

Is puberty an accelerator of type 1 diabetes in IL6-174CC females?

Diabetes 2005 Apr;54(4):1245-8

Department of Diabetes and Metabolism, Division of Medicine, University of Bristol, UK.

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http://dx.doi.org/10.2337/diabetes.54.4.1245DOI Listing
April 2005

The rising incidence of childhood type 1 diabetes and reduced contribution of high-risk HLA haplotypes.

Lancet 2004 Nov 6-12;364(9446):1699-700

Diabetes and Metabolism, Division of Medicine, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1016/S0140-6736(04)17357-1DOI Listing
November 2004

Analysis of the vitamin D receptor gene sequence variants in type 1 diabetes.

Diabetes 2004 Oct;53(10):2709-12

Juvenile Diabetes Research Foundation/Wellcome Trust DiabetesInflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, WT/MRC building, Addenbrooke's Hospital, Cambridge, CB2 2XY, UK.

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http://dx.doi.org/10.2337/diabetes.53.10.2709DOI Listing
October 2004

Association of intercellular adhesion molecule-1 gene with type 1 diabetes.

Lancet 2003 Nov;362(9397):1723-4

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, CB2 2XY, Cambridge, UK.

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http://dx.doi.org/10.1016/S0140-6736(03)14847-7DOI Listing
November 2003

Identifying hepatic nuclear factor 1alpha mutations in children and young adults with a clinical diagnosis of type 1 diabetes.

Diabetes Care 2003 Feb;26(2):333-7

Department of Diabetes and Metabolism, Division of Medicine, University of Bristol, UK.

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http://dx.doi.org/10.2337/diacare.26.2.333DOI Listing
February 2003

High familial risk and genetic susceptibility in early onset childhood diabetes.

Diabetes 2002 Jan;51(1):210-4

Department of Diabetes and Metabolism, Division of Medicine, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.2337/diabetes.51.1.210DOI Listing
January 2002