Kathleen J Millen

Kathleen J Millen

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Kathleen J Millen

Kathleen J Millen

Publications by authors named "Kathleen J Millen"

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Early dorsomedial tissue interactions regulate gyrification of distal neocortex.

Nat Commun 2019 11 15;10(1):5192. Epub 2019 Nov 15.

Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, 98101, USA.

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http://dx.doi.org/10.1038/s41467-019-12913-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858446PMC
November 2019

PI3K-Yap activity drives cortical gyrification and hydrocephalus in mice.

Elife 2019 05 16;8. Epub 2019 May 16.

Center for Integrative Brain Research, Seattle Children's Research Institute, Washington, United States.

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http://dx.doi.org/10.7554/eLife.45961DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544437PMC
May 2019

What cerebellar malformations tell us about cerebellar development.

Neurosci Lett 2019 01 23;688:14-25. Epub 2018 May 23.

Seattle Children's Research Institute, Center for Integrative Brain Research, Seattle, WA, United States; University of Washington, Department of Pediatrics, Division of Genetics, Seattle, WA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.neulet.2018.05.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240394PMC
January 2019

Embryology.

Handb Clin Neurol 2018 ;154:29-44

Seattle Children's Research Institute, Center for Integrative Brain Research, Seattle, WA, United States; Department of Pediatrics, Genetics Division, University of Washington, Seattle, WA, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/B97804446395610
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http://dx.doi.org/10.1016/B978-0-444-63956-1.00002-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231496PMC
September 2018

ZIC1 Function in Normal Cerebellar Development and Human Developmental Pathology.

Adv Exp Med Biol 2018 ;1046:249-268

Department of Pediatrics, University of Washington School of Medicine, Seattle Children's Hospital Research Institute, Center for Integrative Brain Research, Seattle, WA, USA.

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http://dx.doi.org/10.1007/978-981-10-7311-3_13DOI Listing
July 2018

Two Hundred Thirty-Six Children With Developmental Hydrocephalus: Causes and Clinical Consequences.

J Child Neurol 2016 Mar 16;31(3):309-20. Epub 2015 Jul 16.

Department of Neurology, University of Washington, Seattle, WA, USA Department of Pediatrics, University of Washington, Seattle, WA, USA Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.

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http://dx.doi.org/10.1177/0883073815592222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990005PMC
March 2016

Sensory and spinal inhibitory dorsal midline crossing is independent of Robo3.

Front Neural Circuits 2015 23;9:36. Epub 2015 Jul 23.

Neuroscience Program, Weill Cornell Graduate School of Medical Sciences New York, NY, USA ; Developmental Biology Program, Sloan-Kettering Institute New York, NY, USA.

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http://dx.doi.org/10.3389/fncir.2015.00036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511845PMC
February 2016

Mouse models of human PIK3CA-related brain overgrowth have acutely treatable epilepsy.

Elife 2015 Dec 3;4. Epub 2015 Dec 3.

Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, United States.

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http://dx.doi.org/10.7554/eLife.12703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744197PMC
December 2015

Foxc1 dependent mesenchymal signalling drives embryonic cerebellar growth.

Elife 2014 Dec 16;3. Epub 2014 Dec 16.

Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, United States.

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http://dx.doi.org/10.7554/eLife.03962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281880PMC
December 2014

The role of Zic genes in inner ear development in the mouse: Exploring mutant mouse phenotypes.

Dev Dyn 2014 Nov 16;243(11):1487-98. Epub 2014 Sep 16.

Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan; Cellular and Molecular Biology Graduate Program, University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1002/dvdy.24186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206579PMC
November 2014

The Developmental Brain Disorders Database (DBDB): a curated neurogenetics knowledge base with clinical and research applications.

Am J Med Genet A 2014 Jun 3;164A(6):1503-11. Epub 2014 Apr 3.

Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington; Division of Genetic Medicine, Department of Pediatrics, University of Washington, Seattle, Washington.

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http://dx.doi.org/10.1002/ajmg.a.36517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279915PMC
June 2014

Systemic glycerol decreases neonatal rabbit brain and cerebellar growth independent of intraventricular hemorrhage.

Pediatr Res 2014 Mar 17;75(3):389-94. Epub 2013 Dec 17.

Department of Pediatrics, University of Washington, Seattle, Washington.

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http://dx.doi.org/10.1038/pr.2013.236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943708PMC
March 2014

Purkinje cell compartmentalization in the cerebellum of the spontaneous mutant mouse dreher.

Brain Struct Funct 2014 Jan 18;219(1):35-47. Epub 2012 Nov 18.

Department of Pathology and Immunology, Baylor College of Medicine, Jan and Dan Duncan Neurological Research Institute of Texas Children's Hospital, 1250 Moursund Street, Suite 1325, Houston, TX, 77030, USA,

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http://dx.doi.org/10.1007/s00429-012-0482-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140632PMC
January 2014

Cerebellar Malformation: Deficits in early neural tube identity found in CHARGE syndrome.

Elife 2013 Dec 24;2:e01873. Epub 2013 Dec 24.

Parthiv Haldipur is in the Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, United States

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http://elifesciences.org/content/elife/2/e01873.full.pdf
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http://elifesciences.org/lookup/doi/10.7554/eLife.01873
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http://dx.doi.org/10.7554/eLife.01873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870571PMC
December 2013

Midbrain and hindbrain malformations: advances in clinical diagnosis, imaging, and genetics.

Lancet Neurol 2013 Apr 18;12(4):381-93. Epub 2013 Mar 18.

Division of Genetic Medicine, Department of Pediatrics, University of Washington Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.

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http://dx.doi.org/10.1016/S1474-4422(13)70024-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158743PMC
April 2013

WDR81 is necessary for purkinje and photoreceptor cell survival.

J Neurosci 2013 Apr;33(16):6834-44

Department of Neurology, University of Chicago Center for Peripheral Neuropathy, University of Chicago, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.2394-12.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618862PMC
April 2013

Wormless without wingless.

Nat Med 2011 Jun;17(6):663-5

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http://dx.doi.org/10.1038/nm0611-663DOI Listing
June 2011

Novel approaches to studying the genetic basis of cerebellar development.

Cerebellum 2010 Sep;9(3):272-83

Department of Human Genetics, The University of Chicago, 920 E 58th Street, CLSC 319, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1007/s12311-010-0169-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921561PMC
September 2010

Phenotypic and genetic analysis of the cerebellar mutant tmgc26, a new ENU-induced ROR-alpha allele.

Eur J Neurosci 2010 Sep 16;32(5):707-16. Epub 2010 Aug 16.

Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1111/j.1460-9568.2010.07330.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974799PMC
September 2010

A developmental and genetic classification for midbrain-hindbrain malformations.

Brain 2009 Dec;132(Pt 12):3199-230

Neuroradiology Room L371, University of California at San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143-0628, USA.

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http://dx.doi.org/10.1093/brain/awp247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792369PMC
December 2009

Looking at cerebellar malformations through text-mined interactomes of mice and humans.

PLoS Comput Biol 2009 Nov 6;5(11):e1000559. Epub 2009 Nov 6.

Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America.

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https://dx.plos.org/10.1371/journal.pcbi.1000559
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http://dx.doi.org/10.1371/journal.pcbi.1000559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2767227PMC
November 2009

Lmx1a maintains proper neurogenic, sensory, and non-sensory domains in the mammalian inner ear.

Dev Biol 2009 Sep 18;333(1):14-25. Epub 2009 Jun 18.

National Institute on Deafness and Other Communication Disorders, 5 Research Court, Rm 2B34, Rockville, Rockville, MD 20850, USA.

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http://dx.doi.org/10.1016/j.ydbio.2009.06.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400700PMC
September 2009

Overlapping function of Lmx1a and Lmx1b in anterior hindbrain roof plate formation and cerebellar growth.

J Neurosci 2009 Sep;29(36):11377-84

Committee on Neurobiology and Department of Human Genetics, The University of Chicago, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.0969-09.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765661PMC
September 2009

Understanding cerebellar pattern formation.

J Vis Exp 2007 1(9):407. Epub 2007 Nov 1.

Department of Neurology, University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.3791/407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566324PMC
February 2009

In ovo electroporations of HH stage 10 chicken embryos.

J Vis Exp 2007 1(9):408. Epub 2007 Nov 1.

Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.3791/408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566325PMC
February 2009

Lmx1a is required for segregation of sensory epithelia and normal ear histogenesis and morphogenesis.

Cell Tissue Res 2008 Dec 5;334(3):339-58. Epub 2008 Nov 5.

Department of Biomedical Sciences, Creighton University, Omaha, NE, USA.

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http://dx.doi.org/10.1007/s00441-008-0709-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654344PMC
December 2008

Zic1 and Zic4 regulate zebrafish roof plate specification and hindbrain ventricle morphogenesis.

Dev Biol 2008 Feb 15;314(2):376-92. Epub 2007 Dec 15.

The Committee on Neurobiology, University of Chicago, 947 East 58th Street, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.ydbio.2007.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268115PMC
February 2008

Cerebellar development and disease.

Curr Opin Neurobiol 2008 Feb 29;18(1):12-9. Epub 2008 May 29.

Department of Human Genetics, University of Chicago, Cummings Life Sciences Center 319, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.conb.2008.05.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2474776PMC
February 2008

A developmental classification of malformations of the brainstem.

Ann Neurol 2007 Dec;62(6):625-39

Department of Radiology, Neurology Pediatrics, University of California at San Francisco, San Francisco, CA 94143-0628, USA.

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http://dx.doi.org/10.1002/ana.21239DOI Listing
December 2007

Proprioceptive sensory neuropathy in mice with a mutation in the cytoplasmic Dynein heavy chain 1 gene.

J Neurosci 2007 Dec;27(52):14515-24

Jack Miller Center for Peripheral Neuropathy and Department of Neurology, The University of Chicago, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.4338-07.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673431PMC
December 2007

Mapping of deletion and translocation breakpoints in 1q44 implicates the serine/threonine kinase AKT3 in postnatal microcephaly and agenesis of the corpus callosum.

Am J Hum Genet 2007 Aug 13;81(2):292-303. Epub 2007 Jun 13.

Academic Unit of Medical Genetics and Regional Genetic Service, St. Mary's Hospital, and Centre for Molecular Medicine, The University of Manchester, M13 0JH, UK.

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http://dx.doi.org/10.1086/519999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950798PMC
August 2007

Molecular definition of an allelic series of mutations disrupting the mouse Lmx1a (dreher) gene.

Mamm Genome 2006 Oct 3;17(10):1025-32. Epub 2006 Oct 3.

Department of Human Genetics, University of Chicago, 920 E. 58th Street, CLSC 319, Chicago, Illinois, 60637, USA.

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http://dx.doi.org/10.1007/s00335-006-0033-7DOI Listing
October 2006

The roof plate regulates cerebellar cell-type specification and proliferation.

Development 2006 Aug 21;133(15):2793-804. Epub 2006 Jun 21.

Department of Human Genetics, University of Chicago, 920 E. 58th Street, CLSC 319 Chicago, IL 60637, USA.

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http://dx.doi.org/10.1242/dev.02441DOI Listing
August 2006

Roof plate-dependent patterning of the vertebrate dorsal central nervous system.

Dev Biol 2005 Jan;277(2):287-95

Department of Human Genetics, University of Chicago, 920 E. 58th Street, CLSC 319, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.ydbio.2004.10.011DOI Listing
January 2005

Development and malformations of the cerebellum in mice.

Mol Genet Metab 2003 Sep-Oct;80(1-2):54-65

Department of Human Genetics, University of Chicago, 920 E 58th Street, CLSC 319, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.ymgme.2003.08.019DOI Listing
November 2004

Heterozygous deletion of the linked genes ZIC1 and ZIC4 is involved in Dandy-Walker malformation.

Nat Genet 2004 Oct 29;36(10):1053-5. Epub 2004 Aug 29.

Department of Human Genetics, The University of Chicago, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1038/ng1420DOI Listing
October 2004

Mechanisms of roof plate formation in the vertebrate CNS.

Nat Rev Neurosci 2004 Oct;5(10):808-12

Department of Human Genetics, University of Chicago, 920 East 58th Street, CLSC 319, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1038/nrn1520DOI Listing
October 2004

Control of roof plate formation by Lmx1a in the developing spinal cord.

Development 2004 Jun;131(11):2693-705

Department of Human Genetics, University of Chicago, 920 East 58th Street, CLSC 319, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1242/dev.01139DOI Listing
June 2004

Control of roof plate development and signaling by Lmx1b in the caudal vertebrate CNS.

J Neurosci 2004 Jun;24(25):5694-703

Department of Human Genetics, University of Chicago, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.0758-04.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6729212PMC
June 2004