Publications Authored by Kathleen J Millen

Early dorsomedial tissue interactions regulate gyrification of distal neocortex.

Authors:

Victor V Chizhikov Igor Y Iskusnykh Ekaterina Y Steshina Nikolai Fattakhov Anne G Lindgren Ashwin S Shetty Achira Roy Shubha Tole Kathleen J Millen

Nat Commun 2019 11 15;10(1):5192. Epub 2019 Nov 15.

Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, 98101, USA.

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http://dx.doi.org/10.1038/s41467-019-12913-z	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858446	PMC

November 2019

Spatiotemporal expansion of primary progenitor zones in the developing human cerebellum.

Science 2019 10 17;366(6464):454-460. Epub 2019 Oct 17.

Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.

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http://dx.doi.org/10.1126/science.aax7526	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897295	PMC

October 2019

Redefining the Etiologic Landscape of Cerebellar Malformations.

Am J Hum Genet 2019 Sep 29;105(3):606-615. Epub 2019 Aug 29.

Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA 98101, USA; Department of Pediatrics, University of Washington, Seattle, WA 98105, USA; Department of Neurology, University of Washington, Seattle, WA 98105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2019.07.019	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731369	PMC

September 2019

PI3K-Yap activity drives cortical gyrification and hydrocephalus in mice.

Authors:

Achira Roy Rory M Murphy Mei Deng James W MacDonald Theo K Bammler Kimberly A Aldinger Ian A Glass Kathleen J Millen

Elife 2019 05 16;8. Epub 2019 May 16.

Center for Integrative Brain Research, Seattle Children's Research Institute, Washington, United States.

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http://dx.doi.org/10.7554/eLife.45961	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544437	PMC

May 2019

What cerebellar malformations tell us about cerebellar development.

Authors:

Parthiv Haldipur Kathleen J Millen

Neurosci Lett 2019 01 23;688:14-25. Epub 2018 May 23.

Seattle Children's Research Institute, Center for Integrative Brain Research, Seattle, WA, United States; University of Washington, Department of Pediatrics, Division of Genetics, Seattle, WA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.neulet.2018.05.032	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240394	PMC

January 2019

Embryology.

Authors:

Parthiv Haldipur Derek Dang Kathleen J Millen

Handb Clin Neurol 2018 ;154:29-44

Seattle Children's Research Institute, Center for Integrative Brain Research, Seattle, WA, United States; Department of Pediatrics, Genetics Division, University of Washington, Seattle, WA, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/B97804446395610	Publisher Site
http://dx.doi.org/10.1016/B978-0-444-63956-1.00002-3	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231496	PMC

September 2018

ZIC1 Function in Normal Cerebellar Development and Human Developmental Pathology.

Authors:

Jun Aruga Kathleen J Millen

Adv Exp Med Biol 2018 ;1046:249-268

Department of Pediatrics, University of Washington School of Medicine, Seattle Children's Hospital Research Institute, Center for Integrative Brain Research, Seattle, WA, USA.

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http://dx.doi.org/10.1007/978-981-10-7311-3_13	DOI Listing

July 2018

Roof Plate-Derived Radial Glial-like Cells Support Developmental Growth of Rapidly Adapting Mechanoreceptor Ascending Axons.

Authors:

Kim Kridsada Jingwen Niu Parthiv Haldipur Zhiping Wang Long Ding Jian J Li Anne G Lindgren Eloisa Herrera Gareth M Thomas Victor V Chizhikov Kathleen J Millen Wenqin Luo

Cell Rep 2018 06;23(10):2928-2941

Department of Neuroscience, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.05.025	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174691	PMC

June 2018

Phenotypic outcomes in Mouse and Human dependent Dandy-Walker cerebellar malformation suggest shared mechanisms.

Authors:

Parthiv Haldipur Derek Dang Kimberly A Aldinger Olivia K Janson Fabien Guimiot Homa Adle-Biasette William B Dobyns Joseph R Siebert Rosa Russo Kathleen J Millen

Elife 2017 01 16;6. Epub 2017 Jan 16.

Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, United States.

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http://dx.doi.org/10.7554/eLife.20898	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271606	PMC

January 2017

Consensus Paper: Cerebellar Development.

Cerebellum 2016 12;15(6):789-828

Department of Cell Biology & Anatomy and Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, T2N 4NI, AB, Canada.

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http://dx.doi.org/10.1007/s12311-015-0724-2	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846577	PMC

December 2016

Mutations in CRADD Result in Reduced Caspase-2-Mediated Neuronal Apoptosis and Cause Megalencephaly with a Rare Lissencephaly Variant.

Am J Hum Genet 2016 Nov 20;99(5):1117-1129. Epub 2016 Oct 20.

Department of Biology, Biological Foundations of Behavior Program, Franklin & Marshall College, Lancaster, PA 17604, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.09.010	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097945	PMC

November 2016

Two Hundred Thirty-Six Children With Developmental Hydrocephalus: Causes and Clinical Consequences.

Authors:

Hannah M Tully Gisele E Ishak Tessa C Rue Jennifer C Dempsey Samuel R Browd Kathleen J Millen Dan Doherty William B Dobyns

J Child Neurol 2016 Mar 16;31(3):309-20. Epub 2015 Jul 16.

Department of Neurology, University of Washington, Seattle, WA, USA Department of Pediatrics, University of Washington, Seattle, WA, USA Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.

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http://dx.doi.org/10.1177/0883073815592222	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990005	PMC

March 2016

Sensory and spinal inhibitory dorsal midline crossing is independent of Robo3.

Authors:

John D Comer Fong Cheng Pan Spencer G Willet Parthiv Haldipur Kathleen J Millen Christopher V E Wright Julia A Kaltschmidt

Front Neural Circuits 2015 23;9:36. Epub 2015 Jul 23.

Neuroscience Program, Weill Cornell Graduate School of Medical Sciences New York, NY, USA ; Developmental Biology Program, Sloan-Kettering Institute New York, NY, USA.

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http://dx.doi.org/10.3389/fncir.2015.00036	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511845	PMC

February 2016

Active medulloblastoma enhancers reveal subgroup-specific cellular origins.

Nature 2016 Feb 27;530(7588):57-62. Epub 2016 Jan 27.

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature16546	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168934	PMC

February 2016

Mouse models of human PIK3CA-related brain overgrowth have acutely treatable epilepsy.

Authors:

Achira Roy Jonathan Skibo Franck Kalume Jing Ni Sherri Rankin Yiling Lu William B Dobyns Gordon B Mills Jean J Zhao Suzanne J Baker Kathleen J Millen

Elife 2015 Dec 3;4. Epub 2015 Dec 3.

Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, United States.

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http://dx.doi.org/10.7554/eLife.12703	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744197	PMC

December 2015

The Spontaneous Ataxic Mouse Mutant Tippy is Characterized by a Novel Purkinje Cell Morphogenesis and Degeneration Phenotype.

Authors:

Evelyn K Shih Gabriella Sekerková Gen Ohtsuki Kimberly A Aldinger Victor V Chizhikov Christian Hansel Enrico Mugnaini Kathleen J Millen

Cerebellum 2015 Jun;14(3):292-307

Division of Neurology, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s12311-014-0640-x	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832921	PMC

June 2015

Foxc1 dependent mesenchymal signalling drives embryonic cerebellar growth.

Authors:

Parthiv Haldipur Gwendolyn S Gillies Olivia K Janson Victor V Chizhikov Divakar S Mithal Richard J Miller Kathleen J Millen

Elife 2014 Dec 16;3. Epub 2014 Dec 16.

Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, United States.

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http://dx.doi.org/10.7554/eLife.03962	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281880	PMC

December 2014

The role of Zic genes in inner ear development in the mouse: Exploring mutant mouse phenotypes.

Authors:

Andrew P Chervenak Lisa M Bank Nicole Thomsen Hannah C Glanville-Jones Skibo Jonathan Kathleen J Millen Ruth M Arkell Kate F Barald

Dev Dyn 2014 Nov 16;243(11):1487-98. Epub 2014 Sep 16.

Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan; Cellular and Molecular Biology Graduate Program, University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1002/dvdy.24186	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206579	PMC

November 2014

Mutation of FOXC1 and PITX2 induces cerebral small-vessel disease.

Authors:

Curtis R French Sudha Seshadri Anita L Destefano Myriam Fornage Corey R Arnold Philip J Gage Jonathan M Skarie William B Dobyns Kathleen J Millen Ting Liu William Dietz Tsutomu Kume Marten Hofker Derek J Emery Sarah J Childs Andrew J Waskiewicz Ordan J Lehmann

J Clin Invest 2014 Nov 24;124(11):4877-81. Epub 2014 Sep 24.

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http://dx.doi.org/10.1172/JCI75109	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347243	PMC

November 2014

A novel intergenic ETnII-β insertion mutation causes multiple malformations in polypodia mice.

PLoS Genet 2013 5;9(12):e1003967. Epub 2013 Dec 5.

Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1003967	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854779	PMC

August 2014

The Developmental Brain Disorders Database (DBDB): a curated neurogenetics knowledge base with clinical and research applications.

Authors:

Ghayda M Mirzaa Kathleen J Millen A James Barkovich William B Dobyns Alex R Paciorkowski

Am J Med Genet A 2014 Jun 3;164A(6):1503-11. Epub 2014 Apr 3.

Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington; Division of Genetic Medicine, Department of Pediatrics, University of Washington, Seattle, Washington.

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http://dx.doi.org/10.1002/ajmg.a.36517	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279915	PMC

June 2014

Transformation of the cerebellum into more ventral brainstem fates causes cerebellar agenesis in the absence of Ptf1a function.

Authors:

Kathleen J Millen Ekaterina Y Steshina Igor Y Iskusnykh Victor V Chizhikov

Proc Natl Acad Sci U S A 2014 Apr 14;111(17):E1777-86. Epub 2014 Apr 14.

Seattle Children's Research Institute, Seattle, WA 98101.

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http://dx.doi.org/10.1073/pnas.1315024111	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035921	PMC

April 2014

Both rare and de novo copy number variants are prevalent in agenesis of the corpus callosum but not in cerebellar hypoplasia or polymicrogyria.

Authors:

Samin A Sajan Liliana Fernandez Sahar Esmaeeli Nieh Eric Rider Polina Bukshpun Mari Wakahiro Susan L Christian Jean-Baptiste Rivière Christopher T Sullivan Jyotsna Sudi Michael J Herriges Alexander R Paciorkowski A James Barkovich Joseph T Glessner Kathleen J Millen Hakon Hakonarson William B Dobyns Elliott H Sherr

PLoS Genet 2013 3;9(10):e1003823. Epub 2013 Oct 3.

Department of Pediatrics, Section of Neurology, Baylor College of Medicine, Houston, Texas, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1003823	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789824	PMC

March 2014

Systemic glycerol decreases neonatal rabbit brain and cerebellar growth independent of intraventricular hemorrhage.

Authors:

Christopher M Traudt Ron J McPherson Colin Studholme Kathleen J Millen Sandra E Juul

Pediatr Res 2014 Mar 17;75(3):389-94. Epub 2013 Dec 17.

Department of Pediatrics, University of Washington, Seattle, Washington.

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http://dx.doi.org/10.1038/pr.2013.236	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943708	PMC

March 2014

Purkinje cell compartmentalization in the cerebellum of the spontaneous mutant mouse dreher.

Authors:

Roy V Sillitoe Nicholas A George-Jones Kathleen J Millen Richard Hawkes

Brain Struct Funct 2014 Jan 18;219(1):35-47. Epub 2012 Nov 18.

Department of Pathology and Immunology, Baylor College of Medicine, Jan and Dan Duncan Neurological Research Institute of Texas Children's Hospital, 1250 Moursund Street, Suite 1325, Houston, TX, 77030, USA,

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http://dx.doi.org/10.1007/s00429-012-0482-6	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140632	PMC

January 2014

Cerebellar Malformation: Deficits in early neural tube identity found in CHARGE syndrome.

Authors:

Parthiv Haldipur Kathleen J Millen

Elife 2013 Dec 24;2:e01873. Epub 2013 Dec 24.

Parthiv Haldipur is in the Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, United States

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http://elifesciences.org/content/elife/2/e01873.full.pdf	Web Search
http://elifesciences.org/lookup/doi/10.7554/eLife.01873	Publisher Site
http://dx.doi.org/10.7554/eLife.01873	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870571	PMC

December 2013

Mutations in extracellular matrix genes NID1 and LAMC1 cause autosomal dominant Dandy-Walker malformation and occipital cephaloceles.

Hum Mutat 2013 Aug 28;34(8):1075-9. Epub 2013 May 28.

Department of Pediatrics, The University of Iowa, Iowa City, Iowa52242, USA.

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http://dx.doi.org/10.1002/humu.22351	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714376	PMC

August 2013

Midbrain and hindbrain malformations: advances in clinical diagnosis, imaging, and genetics.

Authors:

Dan Doherty Kathleen J Millen A James Barkovich

Lancet Neurol 2013 Apr 18;12(4):381-93. Epub 2013 Mar 18.

Division of Genetic Medicine, Department of Pediatrics, University of Washington Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.

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http://dx.doi.org/10.1016/S1474-4422(13)70024-3	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158743	PMC

April 2013

WDR81 is necessary for purkinje and photoreceptor cell survival.

Authors:

Maria Traka Kathleen J Millen Devon Collins Benayahu Elbaz Grahame J Kidd Christopher M Gomez Brian Popko

J Neurosci 2013 Apr;33(16):6834-44

Department of Neurology, University of Chicago Center for Peripheral Neuropathy, University of Chicago, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.2394-12.2013	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618862	PMC

April 2013

Cerebellar and posterior fossa malformations in patients with autism-associated chromosome 22q13 terminal deletion.

Authors:

Kimberly A Aldinger Jillene Kogan Virginia Kimonis Bridget Fernandez Denise Horn Eva Klopocki Brian Chung Annick Toutain Rosanna Weksberg Kathleen J Millen A James Barkovich William B Dobyns

Am J Med Genet A 2013 Jan 7;161A(1):131-6. Epub 2012 Dec 7.

Committee on Neurobiology, The University of Chicago, Chicago, IL, USA.

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http://doi.wiley.com/10.1002/ajmg.a.35700	Publisher Site
http://dx.doi.org/10.1002/ajmg.a.35700	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733662	PMC

January 2013

If the skull fits: magnetic resonance imaging and microcomputed tomography for combined analysis of brain and skull phenotypes in the mouse.

Authors:

Brian J Nieman Marissa C Blank Brian B Roman R Mark Henkelman Kathleen J Millen

Physiol Genomics 2012 Oct 4;44(20):992-1002. Epub 2012 Sep 4.

Mouse Imaging Centre, Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1152/physiolgenomics.00093.2012	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472465	PMC

October 2012

Beyond Gómez-López-Hernández syndrome: recurring phenotypic themes in rhombencephalosynapsis.

Authors:

Hannah M Tully Jennifer C Dempsey Gisele E Ishak Margaret P Adam Cynthia J R Curry Pedro Sanchez-Lara Alasdair Hunter Karen W Gripp Judith Allanson Christopher Cunniff Ian Glass Kathleen J Millen Daniel Doherty William B Dobyns

Am J Med Genet A 2012 Oct 10;158A(10):2393-406. Epub 2012 Sep 10.

Division of Pediatric Neurology, Department of Neurology, University of Washington, Seattle, USA.

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http://dx.doi.org/10.1002/ajmg.a.35561	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448816	PMC

October 2012

Consensus paper: pathological role of the cerebellum in autism.

Cerebellum 2012 Sep;11(3):777-807

University of Minnesota Medical School, 420 Delaware St. SE, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1007/s12311-012-0355-9	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677555	PMC

September 2012

Rhombencephalosynapsis: a hindbrain malformation associated with incomplete separation of midbrain and forebrain, hydrocephalus and a broad spectrum of severity.

Authors:

Gisele E Ishak Jennifer C Dempsey Dennis W W Shaw Hannah Tully Margaret P Adam Pedro A Sanchez-Lara Ian Glass Tessa C Rue Kathleen J Millen William B Dobyns Dan Doherty

Brain 2012 May 26;135(Pt 5):1370-86. Epub 2012 Mar 26.

Department of Radiology, Seattle Children's Hospital, 4800 Sand Point Way NE, Seattle WA 98105, USA.

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http://dx.doi.org/10.1093/brain/aws065	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338925	PMC

May 2012

Wormless without wingless.

Authors:

Dan Doherty Kathleen J Millen

Nat Med 2011 Jun;17(6):663-5

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http://dx.doi.org/10.1038/nm0611-663	DOI Listing

June 2011

Multiple developmental programs are altered by loss of Zic1 and Zic4 to cause Dandy-Walker malformation cerebellar pathogenesis.

Authors:

Marissa C Blank Inessa Grinberg Emmanuel Aryee Christine Laliberte Victor V Chizhikov R Mark Henkelman Kathleen J Millen

Development 2011 Mar 9;138(6):1207-16. Epub 2011 Feb 9.

Department of Molecular Genetics, The University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1242/dev.054114	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042874	PMC

March 2011

Novel approaches to studying the genetic basis of cerebellar development.

Authors:

Samin A Sajan Kathryn E Waimey Kathleen J Millen

Cerebellum 2010 Sep;9(3):272-83

Department of Human Genetics, The University of Chicago, 920 E 58th Street, CLSC 319, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1007/s12311-010-0169-6	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921561	PMC

September 2010

Phenotypic and genetic analysis of the cerebellar mutant tmgc26, a new ENU-induced ROR-alpha allele.

Authors:

Douglas J Swanson Ekaterina Y Steshina Paul Wakenight Kimberly A Aldinger Dan Goldowitz Kathleen J Millen Victor V Chizhikov

Eur J Neurosci 2010 Sep 16;32(5):707-16. Epub 2010 Aug 16.

Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1111/j.1460-9568.2010.07330.x	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974799	PMC

September 2010

Lmx1a regulates fates and location of cells originating from the cerebellar rhombic lip and telencephalic cortical hem.

Authors:

Victor V Chizhikov Anne G Lindgren Yuriko Mishima Richard W Roberts Kimberly A Aldinger George R Miesegaes D Spencer Currle Edwin S Monuki Kathleen J Millen

Proc Natl Acad Sci U S A 2010 Jun 24;107(23):10725-30. Epub 2010 May 24.

Department of Human Genetics,University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1073/pnas.0910786107	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890798	PMC

June 2010

A developmental and genetic classification for midbrain-hindbrain malformations.

Authors:

A James Barkovich Kathleen J Millen William B Dobyns

Brain 2009 Dec;132(Pt 12):3199-230

Neuroradiology Room L371, University of California at San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143-0628, USA.

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http://dx.doi.org/10.1093/brain/awp247	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792369	PMC

December 2009

Looking at cerebellar malformations through text-mined interactomes of mice and humans.

Authors:

Ivan Iossifov Raul Rodriguez-Esteban Ilya Mayzus Kathleen J Millen Andrey Rzhetsky

PLoS Comput Biol 2009 Nov 6;5(11):e1000559. Epub 2009 Nov 6.

Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America.

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https://dx.plos.org/10.1371/journal.pcbi.1000559	Publisher Site
http://dx.doi.org/10.1371/journal.pcbi.1000559	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2767227	PMC

November 2009

Lmx1a maintains proper neurogenic, sensory, and non-sensory domains in the mammalian inner ear.

Authors:

Soo Kyung Koo Jennifer K Hill Chan Ho Hwang Zheng Shi Lin Kathleen J Millen Doris K Wu

Dev Biol 2009 Sep 18;333(1):14-25. Epub 2009 Jun 18.

National Institute on Deafness and Other Communication Disorders, 5 Research Court, Rm 2B34, Rockville, Rockville, MD 20850, USA.

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http://dx.doi.org/10.1016/j.ydbio.2009.06.016	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400700	PMC

September 2009

FOXC1 is required for normal cerebellar development and is a major contributor to chromosome 6p25.3 Dandy-Walker malformation.

Authors:

Kimberly A Aldinger Ordan J Lehmann Louanne Hudgins Victor V Chizhikov Alexander G Bassuk Lesley C Ades Ian D Krantz William B Dobyns Kathleen J Millen

Nat Genet 2009 Sep 9;41(9):1037-42. Epub 2009 Aug 9.

Committee on Neurobiology, University of Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.1038/ng.422	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843139	PMC

September 2009

Overlapping function of Lmx1a and Lmx1b in anterior hindbrain roof plate formation and cerebellar growth.

Authors:

Yuriko Mishima Anne G Lindgren Victor V Chizhikov Randy L Johnson Kathleen J Millen

J Neurosci 2009 Sep;29(36):11377-84

Committee on Neurobiology and Department of Human Genetics, The University of Chicago, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.0969-09.2009	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765661	PMC

September 2009

Model organisms inform the search for the genes and developmental pathology underlying malformations of the human hindbrain.

Authors:

Kimberly A Aldinger Gina E Elsen Victoria E Prince Kathleen J Millen

Semin Pediatr Neurol 2009 Sep;16(3):155-63

Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.spen.2009.06.003	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778478	PMC

September 2009

Genetic variation and population substructure in outbred CD-1 mice: implications for genome-wide association studies.

Authors:

Kimberly A Aldinger Greta Sokoloff David M Rosenberg Abraham A Palmer Kathleen J Millen

PLoS One 2009 6;4(3):e4729. Epub 2009 Mar 6.

Committee on Neurobiology, The University of Chicago, Chicago, Illinois, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0004729	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649211	PMC

May 2009

Understanding cerebellar pattern formation.

Authors:

Kathleen J Millen

J Vis Exp 2007 1(9):407. Epub 2007 Nov 1.

Department of Neurology, University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.3791/407	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566324	PMC

February 2009

In ovo electroporations of HH stage 10 chicken embryos.

Authors:

Marissa C Blank Victor Chizhikov Kathleen J Millen

J Vis Exp 2007 1(9):408. Epub 2007 Nov 1.

Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.3791/408	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566325	PMC

February 2009

Lmx1a is required for segregation of sensory epithelia and normal ear histogenesis and morphogenesis.

Authors:

David H Nichols Sarah Pauley Israt Jahan Kirk W Beisel Kathleen J Millen Bernd Fritzsch

Cell Tissue Res 2008 Dec 5;334(3):339-58. Epub 2008 Nov 5.

Department of Biomedical Sciences, Creighton University, Omaha, NE, USA.

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http://dx.doi.org/10.1007/s00441-008-0709-2	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654344	PMC

December 2008

Linkage to chromosome 2q36.1 in autosomal dominant Dandy-Walker malformation with occipital cephalocele and evidence for genetic heterogeneity.

Hum Genet 2008 Apr 19;123(3):237-45. Epub 2008 Jan 19.

Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA,

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http://dx.doi.org/10.1007/s00439-008-0467-y	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822644	PMC

April 2008

Zic1 and Zic4 regulate zebrafish roof plate specification and hindbrain ventricle morphogenesis.

Authors:

Gina E Elsen Louis Y Choi Kathleen J Millen Yevgenya Grinblat Victoria E Prince

Dev Biol 2008 Feb 15;314(2):376-92. Epub 2007 Dec 15.

The Committee on Neurobiology, University of Chicago, 947 East 58th Street, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.ydbio.2007.12.006	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268115	PMC

February 2008

Cerebellar development and disease.

Authors:

Kathleen J Millen Joseph G Gleeson

Curr Opin Neurobiol 2008 Feb 29;18(1):12-9. Epub 2008 May 29.

Department of Human Genetics, University of Chicago, Cummings Life Sciences Center 319, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.conb.2008.05.010	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2474776	PMC

February 2008

A developmental classification of malformations of the brainstem.

Authors:

A James Barkovich Kathleen J Millen William B Dobyns

Ann Neurol 2007 Dec;62(6):625-39

Department of Radiology, Neurology Pediatrics, University of California at San Francisco, San Francisco, CA 94143-0628, USA.

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http://dx.doi.org/10.1002/ana.21239	DOI Listing

December 2007

Proprioceptive sensory neuropathy in mice with a mutation in the cytoplasmic Dynein heavy chain 1 gene.

Authors:

Xiang-Jun Chen Eleni N Levedakou Kathleen J Millen Robert L Wollmann Betty Soliven Brian Popko

J Neurosci 2007 Dec;27(52):14515-24

Jack Miller Center for Peripheral Neuropathy and Department of Neurology, The University of Chicago, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.4338-07.2007	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673431	PMC

December 2007

Cilia proteins control cerebellar morphogenesis by promoting expansion of the granule progenitor pool.

Authors:

Victor V Chizhikov James Davenport Qihong Zhang Evelyn Kim Shih Olga A Cabello Jannon L Fuchs Bradley K Yoder Kathleen J Millen

J Neurosci 2007 Sep;27(36):9780-9

Department of Human Genetics, University of Chicago, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.5586-06.2007	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6672978	PMC

September 2007

Mapping of deletion and translocation breakpoints in 1q44 implicates the serine/threonine kinase AKT3 in postnatal microcephaly and agenesis of the corpus callosum.

Authors:

Elena Boland Jill Clayton-Smith Victoria G Woo Shane McKee Forbes D C Manson Livija Medne Elaine Zackai Eric A Swanson David Fitzpatrick Kathleen J Millen Elliott H Sherr William B Dobyns Graeme C M Black

Am J Hum Genet 2007 Aug 13;81(2):292-303. Epub 2007 Jun 13.

Academic Unit of Medical Genetics and Regional Genetic Service, St. Mary's Hospital, and Centre for Molecular Medicine, The University of Manchester, M13 0JH, UK.

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