Kathleen J Green

Kathleen J Green

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Kathleen J Green

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Keratinocyte cadherin desmoglein 1 controls melanocyte behavior through paracrine signaling.

Pigment Cell Melanoma Res 2020 Mar 10;33(2):305-317. Epub 2019 Oct 10.

Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

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http://dx.doi.org/10.1111/pcmr.12826DOI Listing
March 2020

Desmosomes:  Essential contributors to an integrated intercellular junction network.

F1000Res 2019 30;8. Epub 2019 Dec 30.

Departments of Pathology and Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

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http://dx.doi.org/10.12688/f1000research.20942.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944264PMC
December 2019

The Role of Desmoglein 1 in Gap Junction Turnover Revealed through the Study of SAM Syndrome.

J Invest Dermatol 2019 Aug 26. Epub 2019 Aug 26.

Departments of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA; Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA; Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2019.08.433DOI Listing
August 2019

Desmoglein 1 Regulates Invadopodia by Suppressing EGFR/Erk Signaling in an Erbin-Dependent Manner.

Mol Cancer Res 2019 05 17;17(5):1195-1206. Epub 2019 Jan 17.

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1158/1541-7786.MCR-18-0048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581214PMC
May 2019

Adherens Junctions and Desmosomes Coordinate Mechanics and Signaling to Orchestrate Tissue Morphogenesis and Function: An Evolutionary Perspective.

Cold Spring Harb Perspect Biol 2018 11 1;10(11). Epub 2018 Nov 1.

University of Cologne, Department of Dermatology, Cologne Excellence Cluster on Stress Responses in Aging Associated Diseases (CECAD), Center for Molecular Medicine Cologne (CMMC) at the CECAD Research Center, 50931 Cologne, Germany.

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http://dx.doi.org/10.1101/cshperspect.a029207DOI Listing
November 2018

Desmoplakin maintains gap junctions by inhibiting Ras/MAPK and lysosomal degradation of connexin-43.

J Cell Biol 2018 09 29;217(9):3219-3235. Epub 2018 Jun 29.

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL

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http://dx.doi.org/10.1083/jcb.201710161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123000PMC
September 2018

Epithelial barrier dysfunction in desmoglein-1 deficiency.

J Allergy Clin Immunol 2018 08 27;142(2):702-706.e7. Epub 2018 Apr 27.

Laboratory of Genetics of Monogenic Auto-inflammatory Diseases, Necker Branch, U1163, Necker-Enfants Malades Hospital (AP-HP), Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.04.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078820PMC
August 2018

Filaggrin 2 Deficiency Results in Abnormal Cell-Cell Adhesion in the Cornified Cell Layers and Causes Peeling Skin Syndrome Type A.

J Invest Dermatol 2018 08 27;138(8):1736-1743. Epub 2018 Jun 27.

Department of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; Department of Human Molecular Genetics & Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2018.04.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056331PMC
August 2018

Techniques to stimulate and interrogate cell-cell adhesion mechanics.

Extreme Mech Lett 2018 Apr 7;20:125-139. Epub 2017 Dec 7.

Department of Mechanical Engineering, Northwestern University, Evanston, IL 60208, United States.

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https://linkinghub.elsevier.com/retrieve/pii/S23524316173018
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http://dx.doi.org/10.1016/j.eml.2017.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181239PMC
April 2018

Research Techniques Made Simple: Methodology and Applications of Förster Resonance Energy Transfer (FRET) Microscopy.

J Invest Dermatol 2017 11;137(11):e185-e191

Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA; Department of Dermatology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2017.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800528PMC
November 2017

Epidermolytic Ichthyosis Sine Epidermolysis.

Am J Dermatopathol 2017 Jun;39(6):440-444

*Department of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; †Department of Human Molecular Genetics & Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; ‡Department of Dermatology, Kirov State Medical Academy, Kirov, Russia; §Department of Pathology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; ¶Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; ‖INSERM UMR 1163, Imagine Institute, University Paris Descartes Sorbonne Cité, Paris, France; **Department of Genetics, Necker hospital for sick children, APHP, Paris, France; ††Department of Dermatology and Allergology, Ludwig-Maximilian-University, Munich, Germany; and Departments of ‡‡Pathology, §§Dermatology, and ¶¶Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL.

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http://dx.doi.org/10.1097/DAD.0000000000000674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489912PMC
June 2017

Intermediate Filaments and the Plasma Membrane.

Cold Spring Harb Perspect Biol 2017 Jan 3;9(1). Epub 2017 Jan 3.

Departments of Dermatology and Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611.

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http://dx.doi.org/10.1101/cshperspect.a025866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204322PMC
January 2017

In Vitro Model of the Epidermis: Connecting Protein Function to 3D Structure.

Methods Enzymol 2016 20;569:287-308. Epub 2015 Aug 20.

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA; Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois, USA. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2015.07.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870045PMC
October 2016

Epidermal Desmoglein 1 Expression Is Reduced in Kidney Transplant Recipients Compared with Immunocompetent Patients.

J Invest Dermatol 2016 09 11;136(9):1908-1912. Epub 2016 Jun 11.

Department of Dermatology, Northwestern University, Chicago, Illinois, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5044805PMC
http://dx.doi.org/10.1016/j.jid.2016.06.001DOI Listing
September 2016

Degrees of Freedom: Your Future in Biomedical Research.

J Invest Dermatol 2016 06;136(6):1073-1076

University of Cologne, Department of Dermatology, Cologne Excellence Cluster on Stress Responses in Aging Associated Diseases (CECAD), Center for Molecular Medicine Cologne (CMMC) at the CECAD Research Center, Joseph Stelzmannstrasse 26, 50931, Cologne, Germany.

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http://dx.doi.org/10.1016/j.jid.2016.03.025DOI Listing
June 2016

Plakophilin-2 loss promotes TGF-β1/p38 MAPK-dependent fibrotic gene expression in cardiomyocytes.

J Cell Biol 2016 Feb 8;212(4):425-38. Epub 2016 Feb 8.

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611

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http://jcb.rupress.org/content/212/4/425.full.pdf
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http://www.jcb.org/lookup/doi/10.1083/jcb.201507018
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http://dx.doi.org/10.1083/jcb.201507018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754716PMC
February 2016

Dominant de novo DSP mutations cause erythrokeratodermia-cardiomyopathy syndrome.

Hum Mol Genet 2016 Jan 24;25(2):348-57. Epub 2015 Nov 24.

Department of Genetics, Department of Dermatology and Department of Pathology, Yale University School of Medicine, New Haven, CT, USA,

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http://dx.doi.org/10.1093/hmg/ddv481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706118PMC
January 2016

Severe dermatitis, multiple allergies, and metabolic wasting syndrome caused by a novel mutation in the N-terminal plakin domain of desmoplakin.

J Allergy Clin Immunol 2015 Nov 12;136(5):1268-76. Epub 2015 Jun 12.

Clinical Medicine, Trinity College Dublin, Dublin, Ireland; Pediatric Dermatology, Our Lady's Children's Hospital Crumlin, Dublin, Ireland; National Children's Research Centre, Our Lady's Children's Hospital Crumlin, Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649901PMC
November 2015

Human Schlafen 5 (SLFN5) Is a Regulator of Motility and Invasiveness of Renal Cell Carcinoma Cells.

Mol Cell Biol 2015 Aug 26;35(15):2684-98. Epub 2015 May 26.

Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA Division of Hematology-Oncology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA Division of Hematology-Oncology, Department of Medicine, Jesse Brown Veterans Affairs Medical Center, Chicago, Illinois, USA

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http://mcb.asm.org/content/early/2015/05/21/MCB.00019-15.ful
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http://mcb.asm.org/lookup/doi/10.1128/MCB.00019-15
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http://dx.doi.org/10.1128/MCB.00019-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524119PMC
August 2015

Desmosome regulation and signaling in disease.

Cell Tissue Res 2015 Jun 19;360(3):501-12. Epub 2015 Feb 19.

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.

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http://dx.doi.org/10.1007/s00441-015-2136-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489137PMC
June 2015

GSK3- and PRMT-1-dependent modifications of desmoplakin control desmoplakin-cytoskeleton dynamics.

J Cell Biol 2015 Mar;208(5):597-612

Department of Pathology and Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 Department of Pathology and Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611

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http://dx.doi.org/10.1083/jcb.201406020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347645PMC
March 2015

Plakophilin 3 mediates Rap1-dependent desmosome assembly and adherens junction maturation.

Mol Biol Cell 2014 Nov 10;25(23):3749-64. Epub 2014 Sep 10.

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 R.H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611

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http://dx.doi.org/10.1091/mbc.E14-05-0968DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230782PMC
November 2014

Desmosomes: regulators of cellular signaling and adhesion in epidermal health and disease.

Cold Spring Harb Perspect Med 2014 Nov 3;4(11):a015297. Epub 2014 Nov 3.

Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611 Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611.

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http://dx.doi.org/10.1101/cshperspect.a015297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208714PMC
November 2014

Disease mutations in desmoplakin inhibit Cx43 membrane targeting mediated by desmoplakin-EB1 interactions.

J Cell Biol 2014 Sep;206(6):779-97

Department of Pathology and Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 Department of Pathology and Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611

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http://dx.doi.org/10.1083/jcb.201312110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164953PMC
September 2014

The desmosomal protein desmoglein 1 aids recovery of epidermal differentiation after acute UV light exposure.

J Invest Dermatol 2014 Aug 4;134(8):2154-2162. Epub 2014 Mar 4.

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA. Electronic address:

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http://dx.doi.org/10.1038/jid.2014.124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102640PMC
August 2014

Desmosomes in the heart: a review of clinical and mechanistic analyses.

Cell Commun Adhes 2014 Jun 23;21(3):109-28. Epub 2014 Apr 23.

Department of Pathology, Northwestern University Feinberg School of Medicine , Chicago, IL , USA.

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http://dx.doi.org/10.3109/15419061.2014.906533DOI Listing
June 2014

Different roles of cadherins in the assembly and structural integrity of the desmosome complex.

J Cell Sci 2014 May 7;127(Pt 10):2339-50. Epub 2014 Mar 7.

Cancer Biology Program, Stanford University, Stanford, CA 94305, USA Department of Biology, Stanford University, Stanford, CA 94305, USA Department of Molecular and Cellular Physiology, Stanford University, Stanford, CA 94305, USA

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http://jcs.biologists.org/content/joces/127/10/2339.full.pdf
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http://jcs.biologists.org/lookup/doi/10.1242/jcs.146316
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http://dx.doi.org/10.1242/jcs.146316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021477PMC
May 2014

Plakophilin 2 affects cell migration by modulating focal adhesion dynamics and integrin protein expression.

J Invest Dermatol 2014 Jan 13;134(1):112-122. Epub 2013 Jun 13.

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA. Electronic address:

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http://dx.doi.org/10.1038/jid.2013.266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216696PMC
January 2014

Structural and functional diversity of desmosomes.

Cell Commun Adhes 2013 Dec 8;20(6):171-87. Epub 2013 Nov 8.

Department of Pathology, Northwestern University Feinberg, School of Medicine , Chicago, IL , USA.

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http://jcb.rupress.org/content/193/7/1137.full.pdf
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http://www.tandfonline.com/doi/full/10.3109/15419061.2013.85
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http://dx.doi.org/10.3109/15419061.2013.855204DOI Listing
December 2013

Structure, function, and regulation of desmosomes.

Prog Mol Biol Transl Sci 2013 ;116:95-118

Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1016/B978-0-12-394311-8.00005-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336551PMC
November 2013

Desmosome assembly and dynamics.

Trends Cell Biol 2013 Nov 24;23(11):537-46. Epub 2013 Jul 24.

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S09628924130010
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http://dx.doi.org/10.1016/j.tcb.2013.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913269PMC
November 2013

Phosphorylation of serine 4,642 in the C-terminus of plectin by MNK2 and PKA modulates its interaction with intermediate filaments.

J Cell Sci 2013 Sep 10;126(Pt 18):4195-207. Epub 2013 Jul 10.

Department of Clinical Research-Dermatology, Inselspital Bern University Hospital and University of Bern, 3010 Bern, Switzerland.

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http://dx.doi.org/10.1242/jcs.127779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772390PMC
September 2013

The GEF Bcr activates RhoA/MAL signaling to promote keratinocyte differentiation via desmoglein-1.

J Cell Biol 2013 Aug 12;202(4):653-66. Epub 2013 Aug 12.

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1083/jcb.201304133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747303PMC
August 2013

Montagna Symposium 2012: Keeping it all together--adhesion, the cytoskeleton, and signaling in morphogenesis and tissue function.

J Invest Dermatol 2013 May;133(5):1124-8

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

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http://dx.doi.org/10.1038/jid.2013.59DOI Listing
May 2013

Desmoglein-1/Erbin interaction suppresses ERK activation to support epidermal differentiation.

J Clin Invest 2013 Apr 25;123(4):1556-70. Epub 2013 Mar 25.

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1172/JCI65220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613912PMC
April 2013

Response to Garrod.

J Invest Dermatol 2013 Feb 30;133(2):578-9. Epub 2012 Aug 30.

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http://linkinghub.elsevier.com/retrieve/pii/S0022202X1536095
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http://dx.doi.org/10.1038/jid.2012.276DOI Listing
February 2013

The C-terminal unique region of desmoglein 2 inhibits its internalization via tail-tail interactions.

J Cell Biol 2012 Nov 5;199(4):699-711. Epub 2012 Nov 5.

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1083/jcb.201202105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494854PMC
November 2012

The cellular origins of disease - from bench to bedside.

Authors:
Kathleen J Green

J Cell Sci 2012 Sep;125(Pt 17):3921-2

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http://jcs.biologists.org/lookup/doi/10.1242/jcs.118448
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http://dx.doi.org/10.1242/jcs.118448DOI Listing
September 2012

Fibronectin expression determines skin cell motile behavior.

J Invest Dermatol 2012 Feb 29;132(2):448-57. Epub 2011 Sep 29.

Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1038/jid.2011.297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252482PMC
February 2012

Desmosomal cadherins utilize distinct kinesins for assembly into desmosomes.

J Cell Biol 2011 Dec 19;195(7):1185-203. Epub 2011 Dec 19.

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1083/jcb.201106057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246898PMC
December 2011

Deconstructing the skin: cytoarchitectural determinants of epidermal morphogenesis.

Nat Rev Mol Cell Biol 2011 Aug 23;12(9):565-80. Epub 2011 Aug 23.

Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1038/nrm3175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280198PMC
August 2011

Desmosomes.

Curr Biol 2011 Jul;21(14):R529-31

Northwestern University Feinberg School of Medicine, Department of Pathology, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1016/j.cub.2011.04.035DOI Listing
July 2011

The calcium ATPase SERCA2 regulates desmoplakin dynamics and intercellular adhesive strength through modulation of PKCα signaling.

FASEB J 2011 Mar 14;25(3):990-1001. Epub 2010 Dec 14.

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1096/fj.10-163261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042836PMC
March 2011

Plakoglobin rescues adhesive defects induced by ectodomain truncation of the desmosomal cadherin desmoglein 1: implications for exfoliative toxin-mediated skin blistering.

Am J Pathol 2010 Dec 12;177(6):2921-37. Epub 2010 Nov 12.

Department of Pathology, Northwestern University Feinberg School of Medicine, 303 E. Chicago Ave., Chicago, IL 60611, USA.

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http://dx.doi.org/10.2353/ajpath.2010.100397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993287PMC
December 2010

Plakoglobin regulates cell motility through Rho- and fibronectin-dependent Src signaling.

J Cell Sci 2010 Oct 28;123(Pt 20):3576-86. Epub 2010 Sep 28.

Department of Pathology, 303 E. Chicago Avenue, Northwestern University, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1242/jcs.070391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951470PMC
October 2010

Ordered assembly of the adhesive and electrochemical connections within newly formed intercalated disks in primary cultures of adult rat cardiomyocytes.

J Biomed Biotechnol 2010 12;2010:624719. Epub 2010 May 12.

Division of Pediatric Cardiology, Department of Pediatrics and Communicable Diseases, University of Michigan, 1150 West Medical Center Dr., Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1155/2010/624719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868981PMC
August 2010

Plakophilin 2 couples actomyosin remodeling to desmosomal plaque assembly via RhoA.

Mol Biol Cell 2010 Aug 16;21(16):2844-59. Epub 2010 Jun 16.

Northwestern University Feinberg School of Medicine, Department of Pathology, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1091/mbc.E10-02-0131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921118PMC
August 2010

Detection of differentially expressed basal cell proteins by mass spectrometry.

Mol Cell Proteomics 2010 Feb 30;9(2):351-61. Epub 2009 Nov 30.

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1074/mcp.M900358-MCP200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830845PMC
February 2010

Intercellular junction assembly, dynamics, and homeostasis.

Cold Spring Harb Perspect Biol 2010 Feb;2(2):a000125

Northwestern University Feinberg School of Medicine, Department of Pathology, R.H. Lurie Comprehensive Cancer Center, 303 E. Chicago Ave. Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1101/cshperspect.a000125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828282PMC
February 2010

Desmosomes at a glance.

J Cell Sci 2009 Dec;122(Pt 24):4401-7

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1242/jcs.037457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787455PMC
December 2009

Plakophilins: multifunctional scaffolds for adhesion and signaling.

Curr Opin Cell Biol 2009 Oct 10;21(5):708-16. Epub 2009 Aug 10.

Department of Pathology, Northwestern University Feinberg School of Medicine, 303 E. Chicago Avenue, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1016/j.ceb.2009.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091506PMC
October 2009

Desmoglein 1-dependent suppression of EGFR signaling promotes epidermal differentiation and morphogenesis.

J Cell Biol 2009 Jun 22;185(7):1243-58. Epub 2009 Jun 22.

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1083/jcb.200809044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712955PMC
June 2009

Regulatory roles of the cadherin superfamily.

F1000 Biol Rep 2009 Feb 24;1:13. Epub 2009 Feb 24.

Northwestern University Feinberg School of Medicine, Departments of Pathology and Dermatology 303 E Chicago Avenue, Chicago, IL 60611 USA.

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http://dx.doi.org/10.3410/B1-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920687PMC
February 2009

EGFR and ADAMs cooperate to regulate shedding and endocytic trafficking of the desmosomal cadherin desmoglein 2.

Mol Biol Cell 2009 Jan 5;20(1):328-37. Epub 2008 Nov 5.

Departments of Pathology and Dermatology, and the R. H. Lurie Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1091/mbc.e08-04-0356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613100PMC
January 2009

Plakophilin 2: a critical scaffold for PKC alpha that regulates intercellular junction assembly.

J Cell Biol 2008 May 12;181(4):605-13. Epub 2008 May 12.

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1083/jcb.200712133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386101PMC
May 2008

Enhancement of UVB-induced apoptosis by apigenin in human keratinocytes and organotypic keratinocyte cultures.

Cancer Res 2008 Apr;68(8):3057-65

Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, Kansas City, Kansas, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-2763DOI Listing
April 2008

Intermediate filament assembly: dynamics to disease.

Trends Cell Biol 2008 Jan;18(1):28-37

Department of Pathology, Northwestern University Feinberg School of Medicine, 303 E. Chicago Avenue, Chicago IL 60611, USA.

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http://dx.doi.org/10.1016/j.tcb.2007.11.004DOI Listing
January 2008

Desmoglein-2: a novel regulator of apoptosis in the intestinal epithelium.

Mol Biol Cell 2007 Nov 5;18(11):4565-78. Epub 2007 Sep 5.

Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1091/mbc.e07-05-0426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2043542PMC
November 2007

Desmosomes: new perspectives on a classic.

J Invest Dermatol 2007 Nov;127(11):2499-515

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1038/sj.jid.5701015DOI Listing
November 2007

Plakoglobin deficiency protects keratinocytes from apoptosis.

J Invest Dermatol 2007 Apr 16;127(4):792-801. Epub 2006 Nov 16.

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1038/sj.jid.5700615DOI Listing
April 2007

Discriminating roles of desmosomal cadherins: beyond desmosomal adhesion.

J Dermatol Sci 2007 Jan 1;45(1):7-21. Epub 2006 Dec 1.

Department of Pathology, The R.H. Lurie Cancer Center, Northwestern Feinberg School of Medicine, 303 E. Chicago Avenue, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1016/j.jdermsci.2006.10.006DOI Listing
January 2007

Identification of desmogleins as disease targets.

J Invest Dermatol 2007 Jan 30;127(E1):E15-6. Epub 2007 Jan 30.

Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S0022202X156108
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http://dx.doi.org/10.1038/sj.skinbio.6250004DOI Listing
January 2007

Biochemical characterization of the desmosome.

J Invest Dermatol 2007 Jan 30;127(E1):E4-5. Epub 2007 Jan 30.

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

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http://dx.doi.org/10.1038/sj.skinbio.6250002DOI Listing
January 2007

Milestones in Investigative Dermatology: The Desmosome.

J Invest Dermatol 2007 Jan;127 Suppl 3:E1

University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1038/sj.skinbio.6250007DOI Listing
January 2007

Identification of Desmogleins as Disease Targets.

J Invest Dermatol 2007 Jan;127 Suppl 3:E15-6

Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA; Department of Dermatology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.

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http://dx.doi.org/10.1038/sj.skinbio.6250004DOI Listing
January 2007

Biochemical Characterization of the Desmosome.

J Invest Dermatol 2007 Jan;127 Suppl 3:E4-5

Department of Pathology, Northwestern University Feinberg School of Medicine Chicago Illinois, USA; Department of Dermatology, Northwestern University, Feinberg School of Medicine Chicago Illinois USA.

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http://dx.doi.org/10.1038/sj.skinbio.6250002DOI Listing
January 2007

New insights into the molecular basis of desmoplakin- and desmin-related cardiomyopathies.

J Cell Sci 2006 Dec 14;119(Pt 23):4974-85. Epub 2006 Nov 14.

Clinic of Dermatology, University Hospital, Geneva, Rue Micheli-du-Crest 14, 1211-Geneva 14, Switzerland.

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http://dx.doi.org/10.1242/jcs.03255DOI Listing
December 2006

The differentiation-dependent desmosomal cadherin desmoglein 1 is a novel caspase-3 target that regulates apoptosis in keratinocytes.

J Biol Chem 2006 Feb 14;281(6):3614-24. Epub 2005 Nov 14.

Department of Pathology and Dermatology and Cell Death Regulation Laboratory, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M508258200
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February 2006

Mechanisms of plakoglobin-dependent adhesion: desmosome-specific functions in assembly and regulation by epidermal growth factor receptor.

J Biol Chem 2005 Dec 23;280(48):40355-63. Epub 2005 Sep 23.

Department of Pathology and Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1074/jbc.M506692200DOI Listing
December 2005

Intermediate filament associated proteins.

Adv Protein Chem 2005 ;70:143-202

Departments of Pathology and Dermatology and R.H. Lurie Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1016/S0065-3233(05)70006-1DOI Listing
July 2005

Plakoglobin suppresses keratinocyte motility through both cell-cell adhesion-dependent and -independent mechanisms.

Proc Natl Acad Sci U S A 2005 Apr 1;102(15):5420-5. Epub 2005 Apr 1.

Departments of Pathology and Cell and Molecular Biology, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1073/pnas.0501676102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC556221PMC
April 2005

In vitro methods for investigating desmoplakin-intermediate filament interactions and their role in adhesive strength.

Methods Cell Biol 2004 ;78:757-86

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1016/s0091-679x(04)78026-7DOI Listing
March 2005

Regulation of desmosome assembly and adhesion.

Semin Cell Dev Biol 2004 Dec;15(6):665-77

Department of Pathology, Northwestern University Feinberg School of Medicine, 303 E. Chicago Avenue, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1016/j.semcdb.2004.09.005DOI Listing
December 2004

Coordinated expression of desmoglein 1 and desmocollin 1 regulates intercellular adhesion.

Differentiation 2004 Oct;72(8):419-33

Department of Pathology and Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1111/j.1432-0436.2004.07208008.xDOI Listing
October 2004

Comparative analysis of armadillo family proteins in the regulation of a431 epithelial cell junction assembly, adhesion and migration.

J Invest Dermatol 2004 Sep;123(3):426-33

Departments of Dermatology and Cell Biology, Emory University School of Medicine, 101 Woodruff Circle, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1111/j.0022-202X.2004.23319.xDOI Listing
September 2004

Epidermal growth factor receptor inhibition promotes desmosome assembly and strengthens intercellular adhesion in squamous cell carcinoma cells.

J Biol Chem 2004 Aug 16;279(35):37191-200. Epub 2004 Jun 16.

Departments of Pathology and Dermatology, The Robert H. Lurie Cancer Center, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1074/jbc.M405123200DOI Listing
August 2004

Working out the strength and flexibility of desmosomes.

Nat Rev Mol Cell Biol 2004 Apr;5(4):271-81

Department of Pathology, Robert H. Lurie Cancer Center, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, Illinois 60611, USA.

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http://www.nature.com/articles/nrm1356
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April 2004

p120 catenin associates with kinesin and facilitates the transport of cadherin-catenin complexes to intercellular junctions.

J Cell Biol 2003 Nov;163(3):547-57

Departments of Pathology and Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

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http://www.jcb.org/lookup/doi/10.1083/jcb.200305137
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http://dx.doi.org/10.1083/jcb.200305137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173663PMC
November 2003

Targeting of p0071 to desmosomes and adherens junctions is mediated by different protein domains.

J Cell Sci 2003 Apr;116(Pt 7):1219-33

Institute of Physiological Chemistry, Medical Faculty of the University of Halle, 06097 Halle/Saale, Germany.

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http://dx.doi.org/10.1242/jcs.00275DOI Listing
April 2003

Defining desmosomal plakophilin-3 interactions.

J Cell Biol 2003 Apr 21;161(2):403-16. Epub 2003 Apr 21.

Molecular Cell Biology Unit, Department for Molecular Biomedical Research, Flanders Interuniversity Institute for Biotechnology (VIB)-Ghent University, B-9000 Ghent, Belgium.

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http://dx.doi.org/10.1083/jcb.200303036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172904PMC
April 2003

Loss of adhesion-regulated proteinase production is correlated with invasive activity in oral squamous cell carcinoma.

Cancer 2002 Dec;95(12):2524-33

Department of Cell and Molecular Biology, Northwestern University Medical School, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1002/cncr.10997DOI Listing
December 2002

Proteinase suppression by E-cadherin-mediated cell-cell attachment in premalignant oral keratinocytes.

J Biol Chem 2002 Oct 23;277(41):38159-67. Epub 2002 Jul 23.

Division of Hematology/Oncology, Department of Medicine, Feinberg School of Medicine and the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1074/jbc.M202384200DOI Listing
October 2002

Structures of two intermediate filament-binding fragments of desmoplakin reveal a unique repeat motif structure.

Nat Struct Biol 2002 Aug;9(8):612-20

Department of Structural Biology, Stanford University School of Medicine, 299 Campus Drive West, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/nsb818DOI Listing
August 2002

The barrier function of skin: how to keep a tight lid on water loss.

Trends Cell Biol 2002 Aug;12(8):355-7

Dept of Cell and Molecular Biology, The Feinberg School of Medicine at Northwestern University, 303 E. Chicago Avenue, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1016/s0962-8924(02)02316-4DOI Listing
August 2002

Plakins: a family of versatile cytolinker proteins.

Trends Cell Biol 2002 Jan;12(1):37-45

Dept of Pathology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.

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http://dx.doi.org/10.1016/s0962-8924(01)02180-8DOI Listing
January 2002