Kathleen A McDonough

Kathleen A McDonough

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Kathleen A McDonough

Kathleen A McDonough

Publications by authors named "Kathleen A McDonough"

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Small RNA Mcr11 requires the transcription factor AbmR for stable expression and regulates genes involved in the central metabolism of Mycobacterium tuberculosis.

Mol Microbiol 2020 Feb 16;113(2):504-520. Epub 2019 Dec 16.

Department of Biomedical Sciences, School of Public Health, University at Albany, Albany, NY.

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http://dx.doi.org/10.1111/mmi.14436DOI Listing
February 2020

AbmR (Rv1265) is a novel transcription factor of Mycobacterium tuberculosis that regulates host cell association and expression of the non-coding small RNA Mcr11.

Mol Microbiol 2018 12 21;110(5):811-830. Epub 2018 Oct 21.

Department of Biomedical Sciences, School of Public Health, University at Albany, PO Box 22002, Albany, NY, 12201-2002, USA.

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http://dx.doi.org/10.1111/mmi.14126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282994PMC
December 2018

Cyclic nucleotide signaling in Mycobacterium tuberculosis: an expanding repertoire.

Pathog Dis 2018 07;76(5)

Department of Biomedical Sciences, School of Public Health, University at Albany, SUNY, Albany, NY 12201-2002, USA.

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http://dx.doi.org/10.1093/femspd/fty048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693379PMC
July 2018

Novel structural features drive DNA binding properties of Cmr, a CRP family protein in TB complex mycobacteria.

Nucleic Acids Res 2018 01;46(1):403-420

Department of Biomedical Sciences, School of Public Health, University at Albany, SUNY, Albany, NY 12201, USA.

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http://dx.doi.org/10.1093/nar/gkx1148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758884PMC
January 2018

Combined Bioinformatic and Rational Design Approach To Develop Antimicrobial Peptides against Mycobacterium tuberculosis.

Antimicrob Agents Chemother 2016 05 22;60(5):2757-64. Epub 2016 Apr 22.

Howard P. Isermann Department of Chemical and Biological Engineering and Center for Biotechnology and Interdisciplinary Studies, RPI, Troy, New York, USA

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http://dx.doi.org/10.1128/AAC.00940-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862459PMC
May 2016

Characterization of a cAMP responsive transcription factor, Cmr (Rv1675c), in TB complex mycobacteria reveals overlap with the DosR (DevR) dormancy regulon.

Nucleic Acids Res 2016 Jan 10;44(1):134-51. Epub 2015 Sep 10.

Department of Biomedical Sciences, School of Public Health, University at Albany, SUNY, Albany, NY 12201, USA Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, PO Box 22002, Albany, NY 12201-2002, USA

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http://dx.doi.org/10.1093/nar/gkv889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705688PMC
January 2016

Role of intragenic binding of cAMP responsive protein (CRP) in regulation of the succinate dehydrogenase genes Rv0249c-Rv0247c in TB complex mycobacteria.

Nucleic Acids Res 2015 Jun 4;43(11):5377-93. Epub 2015 May 4.

Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, PO Box 22002, Albany, NY 12201-2002, USA Department of Biomedical Sciences, University at Albany, SUNY, Albany, NY 12201, USA

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http://dx.doi.org/10.1093/nar/gkv420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477654PMC
June 2015

Identification of novel sRNAs in mycobacterial species.

PLoS One 2013 14;8(11):e79411. Epub 2013 Nov 14.

McKetta Department of Chemical Engineering, University of Texas at Austin, Austin, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0079411PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828370PMC
November 2014

Cyclic AMP Signaling in Mycobacteria.

Microbiol Spectr 2014 Apr;2(2)

Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, PO Box 22002, Albany, NY 12222.

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http://dx.doi.org/10.1128/microbiolspec.MGM2-0011-2013DOI Listing
April 2014

Definition and annotation of (myco)bacterial non-coding RNA.

Tuberculosis (Edinb) 2013 Jan 4;93(1):26-9. Epub 2013 Jan 4.

Johns Hopkins University School of Medicine, Center for TB Research, 1550 Orleans St, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1016/j.tube.2012.11.010DOI Listing
January 2013

The myriad roles of cyclic AMP in microbial pathogens: from signal to sword.

Nat Rev Microbiol 2011 Nov 14;10(1):27-38. Epub 2011 Nov 14.

Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, PO Box 22002, Albany, New York, New York 12201-2002, USA. kathleen.mcdonough@ wadsworth.org

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http://dx.doi.org/10.1038/nrmicro2688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785115PMC
November 2011

Dysregulation of serine biosynthesis contributes to the growth defect of a Mycobacterium tuberculosis crp mutant.

Mol Microbiol 2011 Oct 8;82(1):180-98. Epub 2011 Sep 8.

Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, PO Box 22002, Albany, NY 12201-2002, USA.

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http://dx.doi.org/10.1111/j.1365-2958.2011.07806.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785234PMC
October 2011

Cyclic AMP signalling in mycobacteria: redirecting the conversation with a common currency.

Cell Microbiol 2011 Mar 28;13(3):349-58. Epub 2010 Dec 28.

Wadsworth Center, New York State Department of Health, Albany, NY 12201-2002, USA.

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http://dx.doi.org/10.1111/j.1462-5822.2010.01562.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785248PMC
March 2011

Multiple small RNAs identified in Mycobacterium bovis BCG are also expressed in Mycobacterium tuberculosis and Mycobacterium smegmatis.

Nucleic Acids Res 2010 Jul 24;38(12):4067-78. Epub 2010 Feb 24.

Wadsworth Center, New York State Department of Health, PO Box 22002, Albany, NY 12201-2002, USA.

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http://dx.doi.org/10.1093/nar/gkq101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896511PMC
July 2010

Rv1675c (cmr) regulates intramacrophage and cyclic AMP-induced gene expression in Mycobacterium tuberculosis-complex mycobacteria.

Mol Microbiol 2009 Jan 14;71(2):434-48. Epub 2008 Nov 14.

Department of Biomedical Sciences, School of Public Health, University at Albany, Albany, NY 12201, USA.

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http://dx.doi.org/10.1111/j.1365-2958.2008.06541.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845544PMC
January 2009

cAMP levels within Mycobacterium tuberculosis and Mycobacterium bovis BCG increase upon infection of macrophages.

FEMS Immunol Med Microbiol 2009 Jan 6;55(1):68-73. Epub 2008 Dec 6.

New York State Department of Health, Wadsworth Center, Albany, NY 12201-2002, USA.

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http://dx.doi.org/10.1111/j.1574-695X.2008.00500.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222459PMC
January 2009

Expression of the Mycobacterium tuberculosis acr-coregulated genes from the DevR (DosR) regulon is controlled by multiple levels of regulation.

Infect Immun 2008 Jun 7;76(6):2478-89. Epub 2008 Apr 7.

Wadsworth Center, New York State Department of Health, Albany, NY 12201-2002, USA.

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http://dx.doi.org/10.1128/IAI.01443-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423077PMC
June 2008

A Mycobacterium marinum zone of inhibition assay as a method for screening potential antimycobacterial compounds from marine extracts.

Planta Med 2007 Jun 30;73(6):559-63. Epub 2007 May 30.

University of Minnesota Medical School, Department of Anatomy Microbiology and Pathology, Duluth, MN, USA.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-2007-981522
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http://dx.doi.org/10.1055/s-2007-981522DOI Listing
June 2007

Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein.

J Bacteriol 2005 Nov;187(22):7795-804

Wadsworth Center, New York State Department of Health, Albany, 12201-2002, USA.

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http://dx.doi.org/10.1128/JB.187.22.7795-7804.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1280308PMC
November 2005

Identification of cyclic AMP-regulated genes in Mycobacterium tuberculosis complex bacteria under low-oxygen conditions.

J Bacteriol 2005 Apr;187(8):2681-92

New York State Department of Health, University of Albany, 120 New Scotland Ave., Albany, NY 12208, USA.

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http://dx.doi.org/10.1128/JB.187.8.2681-2692.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1070381PMC
April 2005