Katherine N Weilbaecher

Katherine N Weilbaecher

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Katherine N Weilbaecher

Katherine N Weilbaecher

Publications by authors named "Katherine N Weilbaecher"

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43Publications

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Assessment of Copper Nanoclusters for Accurate in Vivo Tumor Imaging and Potential for Translation.

Authors:
Gyu Seong Heo Yongfeng Zhao Deborah Sultan Xiaohui Zhang Lisa Detering Hannah P Luehmann Xiangyu Zhang Richen Li Ankur Choksi Savannah Sharp Sidney Levingston Tina Primeau David E Reichert Guorong Sun Babak Razani Shunqiang Li Katherine N Weilbaecher Farrokh Dehdashti Karen L Wooley Yongjian Liu

ACS Appl Mater Interfaces 2019 Jun 22;11(22):19669-19678. Epub 2019 May 22.

Mallinckrodt Institute of Radiology , Washington University , St. Louis , Missouri 63110 , United States.

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http://dx.doi.org/10.1021/acsami.8b22752DOI Listing
June 2019

Inhibition of the Stromal p38MAPK/MK2 Pathway Limits Breast Cancer Metastases and Chemotherapy-Induced Bone Loss.

Authors:
Bhavna Murali Qihao Ren Xianmin Luo Douglas V Faget Chun Wang Radia Marie Johnson Tina Gruosso Kevin C Flanagan Yujie Fu Kathleen Leahy Elise Alspach Xinming Su Michael H Ross Barry Burnette Katherine N Weilbaecher Morag Park Gabriel Mbalaviele Joseph B Monahan Sheila A Stewart

Cancer Res 2018 10 9;78(19):5618-5630. Epub 2018 Aug 9.

Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri.

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http://dx.doi.org/10.1158/0008-5472.CAN-18-0234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168362PMC
October 2018

The β3-integrin endothelial adhesome regulates microtubule-dependent cell migration.

Authors:
Samuel J Atkinson Aleksander M Gontarczyk Abdullah Aa Alghamdi Tim S Ellison Robert T Johnson Wesley J Fowler Benjamin M Kirkup Bernardo C Silva Bronwen E Harry Jochen G Schneider Katherine N Weilbaecher Mette M Mogensen Mark D Bass Maddy Parsons Dylan R Edwards Stephen D Robinson

EMBO Rep 2018 07 24;19(7). Epub 2018 May 24.

School of Biological Sciences, Norwich Research Park, University of East Anglia, Norwich, UK

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http://dx.doi.org/10.15252/embr.201744578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030693PMC
July 2018

Perfusion-based fluorescence imaging method delineates diverse organs and identifies multifocal tumors using generic near-infrared molecular probes.

Authors:
Jessica Miller Steven T Wang Inema Orukari Julie Prior Gail Sudlow Xinming Su Kexian Liang Rui Tang Elizabeth M C Hillman Katherine N Weilbaecher Joseph P Culver Mikhail Y Berezin Samuel Achilefu

J Biophotonics 2018 04 3;11(4):e201700232. Epub 2018 Jan 3.

Optical Radiology Laboratory, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri.

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http://dx.doi.org/10.1002/jbio.201700232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903995PMC
April 2018

Breast and pancreatic cancer interrupt IRF8-dependent dendritic cell development to overcome immune surveillance.

Authors:
Melissa A Meyer John M Baer Brett L Knolhoff Timothy M Nywening Roheena Z Panni Xinming Su Katherine N Weilbaecher William G Hawkins Cynthia Ma Ryan C Fields David C Linehan Grant A Challen Roberta Faccio Rebecca L Aft David G DeNardo

Nat Commun 2018 03 28;9(1):1250. Epub 2018 Mar 28.

Department of Medicine, Washington University School of Medicine, St. Louis, MO, 63110, USA.

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http://dx.doi.org/10.1038/s41467-018-03600-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871846PMC
March 2018

Bone-Induced Expression of Integrin β3 Enables Targeted Nanotherapy of Breast Cancer Metastases.

Authors:
Michael H Ross Alison K Esser Gregory C Fox Anne H Schmieder Xiaoxia Yang Grace Hu Dipanjan Pan Xinming Su Yalin Xu Deborah V Novack Thomas Walsh Graham A Colditz Gabriel H Lukaszewicz Elizabeth Cordell Joshua Novack James A J Fitzpatrick David L Waning Khalid S Mohammad Theresa A Guise Gregory M Lanza Katherine N Weilbaecher

Cancer Res 2017 11 30;77(22):6299-6312. Epub 2017 Aug 30.

Department of Medicine, Division of Molecular Oncology, Washington University School of Medicine, St. Louis, Missouri.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-1225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841166PMC
November 2017

HTLV-1 viral oncogene HBZ induces osteolytic bone disease in transgenic mice.

Authors:
Alison K Esser Daniel A Rauch Jingyu Xiang John C Harding Nicole A Kohart Michael H Ross Xinming Su Kevin Wu Devra Huey Yalin Xu Kiran Vij Patrick L Green Thomas J Rosol Stefan Niewiesk Lee Ratner Katherine N Weilbaecher

Oncotarget 2017 Sep 27;8(41):69250-69263. Epub 2017 Aug 27.

Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.18632/oncotarget.20565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642476PMC
September 2017

Evaluating Acetate Metabolism for Imaging and Targeting in Multiple Myeloma.

Authors:
Francesca Fontana Xia Ge Xinming Su Deep Hathi Jingyu Xiang Simone Cenci Roberto Civitelli Kooresh I Shoghi Walter J Akers Andre D'avignon Katherine N Weilbaecher Monica Shokeen

Clin Cancer Res 2017 Jan 2;23(2):416-429. Epub 2016 Aug 2.

Department of Radiology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-2134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241171PMC
January 2017

Contact-facilitated drug delivery with Sn2 lipase labile prodrugs optimize targeted lipid nanoparticle drug delivery.

Authors:
Dipanjan Pan Christine T N Pham Katherine N Weilbaecher Michael H Tomasson Samuel A Wickline Gregory M Lanza

Wiley Interdiscip Rev Nanomed Nanobiotechnol 2016 Jan-Feb;8(1):85-106. Epub 2015 Aug 21.

Division of Cardiology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.

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http://doi.wiley.com/10.1002/wnan.1355
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http://dx.doi.org/10.1002/wnan.1355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709477PMC
September 2016

Antagonizing Integrin β3 Increases Immunosuppression in Cancer.

Authors:
Xinming Su Alison K Esser Sarah R Amend Jingyu Xiang Yalin Xu Michael H Ross Gregory C Fox Takayuki Kobayashi Veronica Steri Kirsten Roomp Francesca Fontana Michelle A Hurchla Brett L Knolhoff Melissa A Meyer Elizabeth A Morgan Julia C Tomasson Joshua S Novack Wei Zou Roberta Faccio Deborah V Novack Stephen D Robinson Steven L Teitelbaum David G DeNardo Jochen G Schneider Katherine N Weilbaecher

Cancer Res 2016 06 23;76(12):3484-95. Epub 2016 May 23.

Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-2663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944657PMC
June 2016

Whole Genome Sequence of Multiple Myeloma-Prone C57BL/KaLwRij Mouse Strain Suggests the Origin of Disease Involves Multiple Cell Types.

Authors:
Sarah R Amend William C Wilson Liang Chu Lan Lu Pengyuan Liu Daniel Serie Xinming Su Yalin Xu Dingyan Wang Anthony Gramolini Xiao-Yan Wen Julie O'Neal Michelle Hurchla Celine M Vachon Graham Colditz Ravi Vij Katherine N Weilbaecher Michael H Tomasson

PLoS One 2015 28;10(5):e0127828. Epub 2015 May 28.

Division of Oncology, Washington University School of Medicine, St. Louis, MO, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127828PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447437PMC
April 2016

Dual-therapy with αvβ3-targeted Sn2 lipase-labile fumagillin-prodrug nanoparticles and zoledronic acid in the Vx2 rabbit tumor model.

Authors:
Alison K Esser Anne H Schmieder Michael H Ross Jingyu Xiang Xinming Su Grace Cui Huiying Zhang Xiaoxia Yang John S Allen Todd Williams Samuel A Wickline Dipanjan Pan Gregory M Lanza Katherine N Weilbaecher

Nanomedicine 2016 Jan 27;12(1):201-11. Epub 2015 Oct 27.

Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15499634150019
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http://dx.doi.org/10.1016/j.nano.2015.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727985PMC
January 2016

Stromal-Initiated Changes in the Bone Promote Metastatic Niche Development.

Authors:
Xianmin Luo Yujie Fu Andrew J Loza Bhavna Murali Kathleen M Leahy Megan K Ruhland Margery Gang Xinming Su Ali Zamani Yu Shi Kory J Lavine David M Ornitz Katherine N Weilbaecher Fanxin Long Deborah V Novack Roberta Faccio Gregory D Longmore Sheila A Stewart

Cell Rep 2016 Jan 24;14(1):82-92. Epub 2015 Dec 24.

Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO 63110, USA; ICCE Institute, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706805PMC
January 2016

CXCR4 Protein Epitope Mimetic Antagonist POL5551 Disrupts Metastasis and Enhances Chemotherapy Effect in Triple-Negative Breast Cancer.

Authors:
Jingyu Xiang Michelle A Hurchla Francesca Fontana Xinming Su Sarah R Amend Alison K Esser Garry J Douglas Chidananda Mudalagiriyappa Kathryn E Luker Timothy Pluard Foluso O Ademuyiwa Barbara Romagnoli Gérald Tuffin Eric Chevalier Gary D Luker Michael Bauer Johann Zimmermann Rebecca L Aft Klaus Dembowsky Katherine N Weilbaecher

Mol Cancer Ther 2015 Nov 12;14(11):2473-85. Epub 2015 Aug 12.

Division of Molecular Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.

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http://mct.aacrjournals.org/content/14/11/2473.full.pdf
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http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-15
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http://dx.doi.org/10.1158/1535-7163.MCT-15-0252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784694PMC
November 2015

Small Molecule MYC Inhibitor Conjugated to Integrin-Targeted Nanoparticles Extends Survival in a Mouse Model of Disseminated Multiple Myeloma.

Authors:
Deepti Soodgupta Dipanjan Pan Grace Cui Angana Senpan Xiaoxia Yang Lan Lu Katherine N Weilbaecher Edward V Prochownik Gregory M Lanza Michael H Tomasson

Mol Cancer Ther 2015 Jun 30;14(6):1286-1294. Epub 2015 Mar 30.

Division of Oncology, Department of Medicine, Washington University Medical School, St. Louis, Missouri.

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http://dx.doi.org/10.1158/1535-7163.MCT-14-0774-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571491PMC
June 2015

Thrombospondin-1 regulates bone homeostasis through effects on bone matrix integrity and nitric oxide signaling in osteoclasts.

Authors:
Sarah R Amend Ozge Uluckan Michelle Hurchla Daniel Leib Deborah Veis Novack Matthew Silva William Frazier Katherine N Weilbaecher

J Bone Miner Res 2015 Jan;30(1):106-15

Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.

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http://doi.wiley.com/10.1002/jbmr.2308
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http://dx.doi.org/10.1002/jbmr.2308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403870PMC
January 2015

A randomized phase II trial investigating the effect of platelet function inhibition on circulating tumor cells in patients with metastatic breast cancer.

Authors:
Ryan P Roop Michael J Naughton Catherine Van Poznak Jochen G Schneider Philip E Lammers Timothy J Pluard Farley Johnson Charles S Eby Katherine N Weilbaecher

Clin Breast Cancer 2013 Dec;13(6):409-15

Department of Medicine, Division of Oncology, Washington University School of Medicine in St. Louis, St. Louis, MO.

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http://dx.doi.org/10.1016/j.clbc.2013.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949605PMC
December 2013

Very late antigen-4 (α(4)β(1) Integrin) targeted PET imaging of multiple myeloma.

Authors:
Deepti Soodgupta Michelle A Hurchla Majiong Jiang Alexander Zheleznyak Katherine N Weilbaecher Carolyn J Anderson Michael H Tomasson Monica Shokeen

PLoS One 2013 8;8(2):e55841. Epub 2013 Feb 8.

Department of Medicine, Washington University, St. Louis, Missouri, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0055841PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568146PMC
August 2013

Role of WNT7B-induced noncanonical pathway in advanced prostate cancer.

Authors:
Dali Zheng Keith F Decker Tianhua Zhou Jianquan Chen Zongtai Qi Kathryn Jacobs Katherine N Weilbaecher Eva Corey Fanxin Long Li Jia

Mol Cancer Res 2013 May 5;11(5):482-93. Epub 2013 Feb 5.

Center for Pharmacogenomics, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-12-0520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141540PMC
May 2013

Noncompetitive modulation of the proteasome by imidazoline scaffolds overcomes bortezomib resistance and delays MM tumor growth in vivo.

Authors:
Theresa A Lansdell Michelle A Hurchla Jingyu Xiang Stacy Hovde Katherine N Weilbaecher R William Henry Jetze J Tepe

ACS Chem Biol 2013 Mar 11;8(3):578-87. Epub 2012 Dec 11.

Department of Chemistry, Michigan State University, East Lansing, MI, USA.

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http://pubs.acs.org/doi/10.1021/cb300568r
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http://dx.doi.org/10.1021/cb300568rDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600058PMC
March 2013

Antagonism of inhibitor of apoptosis proteins increases bone metastasis via unexpected osteoclast activation.

Authors:
Chang Yang Jennifer L Davis Rong Zeng Paras Vora Xinming Su Lynne I Collins Suwanna Vangveravong Robert H Mach David Piwnica-Worms Katherine N Weilbaecher Roberta Faccio Deborah Veis Novack

Cancer Discov 2013 Feb 26;3(2):212-23. Epub 2012 Dec 26.

Division of Bone and Mineral Diseases, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1158/2159-8290.CD-12-0271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570610PMC
February 2013

Hedgehog-targeted therapeutics uncouple the vicious cycle of bone metastasis.

Authors:
Michelle A Hurchla Katherine N Weilbaecher

Oncoimmunology 2012 Nov;1(8):1411-1413

Department of Medicine; Division of Oncology; Washington University School of Medicine; St. Louis, MO USA.

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http://dx.doi.org/10.4161/onci.21060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518520PMC
November 2012

The ADP receptor P2RY12 regulates osteoclast function and pathologic bone remodeling.

Authors:
Xinming Su Desiree H Floyd Alun Hughes Jingyu Xiang Jochen G Schneider Ozge Uluckan Emanuela Heller Hongju Deng Wei Zou Clarissa S Craft Kaiming Wu Angela C Hirbe Dorota Grabowska Mark C Eagleton Sarah Townsley Lynne Collins David Piwnica-Worms Thomas H Steinberg Deborah V Novack Pamela B Conley Michelle A Hurchla Michael Rogers Katherine N Weilbaecher

J Clin Invest 2012 Oct 17;122(10):3579-92. Epub 2012 Sep 17.

Department of Medicine, Division of Oncology, Washington University in St. Louis School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1172/JCI38576DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461896PMC
October 2012

Integrin α(v)β₃ as a PET imaging biomarker for osteoclast number in mouse models of negative and positive osteoclast regulation.

Authors:
Alexander Zheleznyak Thaddeus J Wadas Christopher D Sherman Jessica M Wilson Paul J Kostenuik Katherine N Weilbaecher Carolyn J Anderson

Mol Imaging Biol 2012 Aug;14(4):500-8

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.

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http://link.springer.com/10.1007/s11307-011-0512-4
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http://dx.doi.org/10.1007/s11307-011-0512-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277818PMC
August 2012

Breast cancer cell targeting by prenylation inhibitors elucidated in living animals with a bioluminescence reporter.

Authors:
Sharon L Chinault Julie L Prior Kevin M Kaltenbronn Anya Penly Katherine N Weilbaecher David Piwnica-Worms Kendall J Blumer

Clin Cancer Res 2012 Aug 12;18(15):4136-44. Epub 2012 Jun 12.

Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-12-0642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605717PMC
August 2012

Hedgehog signaling inhibition blocks growth of resistant tumors through effects on tumor microenvironment.

Authors:
Emanuela Heller Michelle A Hurchla Jingyu Xiang Xinming Su Sara Chen Jochen Schneider Kyu-Sang Joeng Marcos Vidal Leah Goldberg Hongju Deng Mary C Hornick Julie L Prior David Piwnica-Worms Fanxin Long Ross Cagan Katherine N Weilbaecher

Cancer Res 2012 Feb 20;72(4):897-907. Epub 2011 Dec 20.

Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-2681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659806PMC
February 2012

Cancer to bone: a fatal attraction.

Authors:
Katherine N Weilbaecher Theresa A Guise Laurie K McCauley

Nat Rev Cancer 2011 Jun 19;11(6):411-25. Epub 2011 May 19.

Department of Medicine, Division of Molecular Oncology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1038/nrc3055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666847PMC
June 2011

Integrins and bone metastasis: integrating tumor cell and stromal cell interactions.

Authors:
Jochen G Schneider Sarah R Amend Katherine N Weilbaecher

Bone 2011 Jan 17;48(1):54-65. Epub 2010 Sep 17.

Institute for Clinical Biochemistry and Pathobiochemistry, University of Wuerzburg, Germany.

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http://dx.doi.org/10.1016/j.bone.2010.09.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010439PMC
January 2011

The ARF tumor suppressor regulates bone remodeling and osteosarcoma development in mice.

Authors:
Daniel A Rauch Michelle A Hurchla John C Harding Hongju Deng Lauren K Shea Mark C Eagleton Stefan Niewiesk Michael D Lairmore David Piwnica-Worms Thomas J Rosol Jason D Weber Lee Ratner Katherine N Weilbaecher

PLoS One 2010 Dec 30;5(12):e15755. Epub 2010 Dec 30.

Division of Molecular Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0015755PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012707PMC
December 2010

Dissection of platelet and myeloid cell defects by conditional targeting of the beta3-integrin subunit.

Authors:
Elizabeth A Morgan Jochen G Schneider Timothy E Baroni Ozge Uluçkan Emanuela Heller Michelle A Hurchla Hongju Deng Desiree Floyd Andrew Berdy Julie L Prior David Piwnica-Worms Steven L Teitelbaum F Patrick Ross Katherine N Weilbaecher

FASEB J 2010 Apr 20;24(4):1117-27. Epub 2009 Nov 20.

Department of Medicine, Mallinkrodt Institute of Radiology, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1096/fj.09-138420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845430PMC
April 2010

Targeting the alphavbeta3 integrin for small-animal PET/CT of osteolytic bone metastases.

Authors:
Thaddeus J Wadas Hongju Deng Jennifer E Sprague Alexander Zheleznyak Katherine N Weilbaecher Carolyn J Anderson

J Nucl Med 2009 Nov;50(11):1873-80

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.2967/jnumed.109.067140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836828PMC
November 2009

CD47 regulates bone mass and tumor metastasis to bone.

Authors:
Ozge Uluçkan Stephanie N Becker Hongju Deng Wei Zou Julie L Prior David Piwnica-Worms William A Frazier Katherine N Weilbaecher

Cancer Res 2009 Apr 10;69(7):3196-204. Epub 2009 Mar 10.

Division of Oncology, Department of Medicine and Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-3358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763641PMC
April 2009

Interferon-gamma targets cancer cells and osteoclasts to prevent tumor-associated bone loss and bone metastases.

Authors:
Zhiqiang Xu Michelle A Hurchla Hongju Deng Ozge Uluçkan Fang Bu Andrew Berdy Mark C Eagleton Emanuela A Heller Desiree H Floyd Wessel P Dirksen Sherry Shu Yuetsu Tanaka Soledad A Fernandez Thomas J Rosol Katherine N Weilbaecher

J Biol Chem 2009 Feb 5;284(7):4658-66. Epub 2008 Dec 5.

Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri 63110.

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http://dx.doi.org/10.1074/jbc.M804812200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640973PMC
February 2009

Advancing treatment for metastatic bone cancer: consensus recommendations from the Second Cambridge Conference.

Authors:
Robert E Coleman Theresa A Guise Allan Lipton G David Roodman James R Berenson Jean-Jacques Body Brendan F Boyce Laura M Calvi Peyman Hadji Eugene V McCloskey Fred Saad Matthew R Smith Larry J Suva Russell S Taichman Robert L Vessella Katherine N Weilbaecher

Clin Cancer Res 2008 Oct;14(20):6387-95

The University of Sheffield Cancer Research Centre, Sheffield, UK.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-08-1572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763638PMC
October 2008

RelB is the NF-kappaB subunit downstream of NIK responsible for osteoclast differentiation.

Authors:
Sergio Vaira Trevor Johnson Angela C Hirbe Muhammad Alhawagri Imani Anwisye Benedicte Sammut Julie O'Neal Wei Zou Katherine N Weilbaecher Roberta Faccio Deborah Veis Novack

Proc Natl Acad Sci U S A 2008 Mar 5;105(10):3897-902. Epub 2008 Mar 5.

Division of Bone and Mineral Diseases, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1073/pnas.0708576105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268780PMC
March 2008

Isolation and molecular profiling of bone marrow micrometastases identifies TWIST1 as a marker of early tumor relapse in breast cancer patients.

Authors:
Mark A Watson Lourdes R Ylagan Kathryn M Trinkaus William E Gillanders Michael J Naughton Katherine N Weilbaecher Timothy P Fleming Rebecca L Aft

Clin Cancer Res 2007 Sep;13(17):5001-9

Department of Pathology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-0024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680916PMC
September 2007

Disruption of CXCR4 enhances osteoclastogenesis and tumor growth in bone.

Authors:
Angela C Hirbe Jessica Rubin Ozge Uluçkan Elizabeth A Morgan Mark C Eagleton Julie L Prior David Piwnica-Worms Katherine N Weilbaecher

Proc Natl Acad Sci U S A 2007 Aug 22;104(35):14062-7. Epub 2007 Aug 22.

Department of Medicine, Division of Oncology, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1073/pnas.0705203104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1955795PMC
August 2007

Noninvasive imaging of osteoclasts in parathyroid hormone-induced osteolysis using a 64Cu-labeled RGD peptide.

Authors:
Jennifer E Sprague Hideki Kitaura Wei Zou Yunpeng Ye Samuel Achilefu Katherine N Weilbaecher Steven L Teitelbaum Carolyn J Anderson

J Nucl Med 2007 Feb;48(2):311-8

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711534PMC
February 2007

Advances in treating metastatic bone cancer: summary statement for the First Cambridge Conference.

Authors:
Allan Lipton James R Berenson Jean-Jacques Body Brendan F Boyce Oyvind S Bruland Michael A Carducci Charles S Cleeland Denis R Clohisy Robert E Coleman Richard J Cook Theresa A Guise Roger N Pearse Trevor J Powles Michael J Rogers G David Roodman Matthew R Smith Larry J Suva Robert L Vessella Katherine N Weilbaecher Laura King

Clin Cancer Res 2006 Oct;12(20 Pt 2):6209s-6212s

Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, Pennsylvania 17033-0850, USA, and Department of Oncology, Norwegian Radium Hospital, Oslo, Norway.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-1213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705325PMC
October 2006

Platelet and osteoclast beta3 integrins are critical for bone metastasis.

Authors:
Suzanne J Bakewell Patrick Nestor Srinivasa Prasad Michael H Tomasson Nikki Dowland Mukund Mehrotra Robert Scarborough James Kanter Keith Abe David Phillips Katherine N Weilbaecher

Proc Natl Acad Sci U S A 2003 Nov 11;100(24):14205-10. Epub 2003 Nov 11.

Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR and Division of Oncology, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.1073/pnas.2234372100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC283570PMC
November 2003

Comparison of five antibodies as markers in the diagnosis of melanoma in cytologic preparations.

Authors:
Matthew V Sheffield Herman Yee Christine C Dorvault Katherine N Weilbaecher Isam A Eltoum Gene P Siegal David E Fisher David C Chhieng

Am J Clin Pathol 2002 Dec;118(6):930-6

Department of Pathology, University of Alabama at Birmingham, 35249-6823, USA.

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http://dx.doi.org/10.1309/EWK9-LUPR-6BC5-1GXVDOI Listing
December 2002

The melanocyte-specific isoform of the microphthalmia transcription factor affects the phenotype of human melanoma.

Authors:
Edgar Selzer Volker Wacheck Trevor Lucas Elisabeth Heere-Ress Min Wu Katherine N Weilbaecher Werner Schlegel Peter Valent Fritz Wrba Hubert Pehamberger David Fisher Burkhard Jansen

Cancer Res 2002 Apr;62(7):2098-103

Department of Radiotherapy and Radiobiology, University Hospital Vienna, 1090 Vienna, Austria.

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April 2002

Role for microphthalmia transcription factor in the diagnosis of metastatic malignant melanoma.

Authors:
Scott R Granter Katherine N Weilbaecher Catherine Quigley David E Fisher

Appl Immunohistochem Mol Morphol 2002 Mar;10(1):47-51

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.

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March 2002