Katherine N Weilbaecher

In Vivo Tumorigenesis, Osteolytic Sarcomas, and Tumorigenic Cell Lines from Transgenic Mice Expressing the Human T-Lymphotropic Virus Type 1 (HTLV-1) Tax Viral Oncogene.

Authors:

Lisa G Lanigan Blake E Hildreth Wessel P Dirksen Jessica K Simmons Chelsea K Martin Jillian L Werbeck Nandu K Thudi Tracey L Papenfuss Prosper N Boyaka Ramiro E Toribio Jerrold M Ward Katherine N Weilbaecher Thomas J Rosol

Am J Pathol 2020 Nov 9. Epub 2020 Nov 9.

Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio; Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio. Electronic address:

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November 2020

Hepatic lipids promote liver metastasis.

Authors:

Yongjia Li Xinming Su Nidhi Rohatgi Yan Zhang Jonathan R Brestoff Kooresh I Shoghi Yalin Xu Clay F Semenkovich Charles A Harris Lindsay L Peterson Katherine N Weilbaecher Steven L Teitelbaum Wei Zou

JCI Insight 2020 09 3;5(17). Epub 2020 Sep 3.

Division of Anatomic and Molecular Pathology, Department of Pathology and Immunology, and.

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September 2020

Nanotherapy delivery of c-myc inhibitor targets Protumor Macrophages and preserves Antitumor Macrophages in Breast Cancer.

Authors:

Alison K Esser Michael H Ross Francesca Fontana Xinming Su Ariel Gabay Gregory C Fox Yalin Xu Jingyu Xiang Anne H Schmieder Xiaoxia Yang Grace Cui Michael Scott Samuel Achilefu Jay Chauhan Steven Fletcher Gregory M Lanza Katherine N Weilbaecher

Theranostics 2020 12;10(17):7510-7526. Epub 2020 Jun 12.

Department of Medicine, Division of Molecular Oncology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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June 2020

Mouse model recapitulates the phenotypic heterogeneity of human adult T-cell leukemia/lymphoma in bone.

Authors:

Nicole A Kohart Said M Elshafae Wachirapan Supsahvad Aylin Alasonyalilar-Demirer Amanda R Panfil Jingyu Xiang Wessel P Dirksen Deborah J Veis Patrick L Green Katherine N Weilbaecher Thomas J Rosol

J Bone Oncol 2019 Dec 20;19:100257. Epub 2019 Aug 20.

Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210, USA.

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December 2019

Parathyroid hormone-related protein promotes bone loss in T-cell leukemia as well as in solid tumors.

Authors:

Nicole A Kohart Said M Elshafae Aylin A Demirer Wessel P Dirksen Justin T Breitbach Sherry T Shu Jingyu Xiang Katherine N Weilbaecher Thomas J Rosol

Leuk Lymphoma 2020 02 8;61(2):409-419. Epub 2019 Oct 8.

Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH, USA.

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February 2020

HTLV-1 viral oncogene HBZ drives bone destruction in adult T cell leukemia.

JCI Insight 2019 10 3;4(19). Epub 2019 Oct 3.

Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.

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October 2019

Assessment of Copper Nanoclusters for Accurate in Vivo Tumor Imaging and Potential for Translation.

ACS Appl Mater Interfaces 2019 Jun 22;11(22):19669-19678. Epub 2019 May 22.

Mallinckrodt Institute of Radiology , Washington University , St. Louis , Missouri 63110 , United States.

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June 2019

Inhibition of the Stromal p38MAPK/MK2 Pathway Limits Breast Cancer Metastases and Chemotherapy-Induced Bone Loss.

Authors:

Bhavna Murali Qihao Ren Xianmin Luo Douglas V Faget Chun Wang Radia Marie Johnson Tina Gruosso Kevin C Flanagan Yujie Fu Kathleen Leahy Elise Alspach Xinming Su Michael H Ross Barry Burnette Katherine N Weilbaecher Morag Park Gabriel Mbalaviele Joseph B Monahan Sheila A Stewart

Cancer Res 2018 10 9;78(19):5618-5630. Epub 2018 Aug 9.

Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri.

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October 2018

The β3-integrin endothelial adhesome regulates microtubule-dependent cell migration.

Authors:

Samuel J Atkinson Aleksander M Gontarczyk Abdullah Aa Alghamdi Tim S Ellison Robert T Johnson Wesley J Fowler Benjamin M Kirkup Bernardo C Silva Bronwen E Harry Jochen G Schneider Katherine N Weilbaecher Mette M Mogensen Mark D Bass Maddy Parsons Dylan R Edwards Stephen D Robinson

EMBO Rep 2018 07 24;19(7). Epub 2018 May 24.

School of Biological Sciences, Norwich Research Park, University of East Anglia, Norwich, UK

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July 2018

Breast and pancreatic cancer interrupt IRF8-dependent dendritic cell development to overcome immune surveillance.

Authors:

Melissa A Meyer John M Baer Brett L Knolhoff Timothy M Nywening Roheena Z Panni Xinming Su Katherine N Weilbaecher William G Hawkins Cynthia Ma Ryan C Fields David C Linehan Grant A Challen Roberta Faccio Rebecca L Aft David G DeNardo

Nat Commun 2018 03 28;9(1):1250. Epub 2018 Mar 28.

Department of Medicine, Washington University School of Medicine, St. Louis, MO, 63110, USA.

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March 2018

Perfusion-based fluorescence imaging method delineates diverse organs and identifies multifocal tumors using generic near-infrared molecular probes.

Authors:

Jessica Miller Steven T Wang Inema Orukari Julie Prior Gail Sudlow Xinming Su Kexian Liang Rui Tang Elizabeth M C Hillman Katherine N Weilbaecher Joseph P Culver Mikhail Y Berezin Samuel Achilefu

J Biophotonics 2018 04 3;11(4):e201700232. Epub 2018 Jan 3.

Optical Radiology Laboratory, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri.

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April 2018

HTLV-1 viral oncogene HBZ induces osteolytic bone disease in transgenic mice.

Authors:

Alison K Esser Daniel A Rauch Jingyu Xiang John C Harding Nicole A Kohart Michael H Ross Xinming Su Kevin Wu Devra Huey Yalin Xu Kiran Vij Patrick L Green Thomas J Rosol Stefan Niewiesk Lee Ratner Katherine N Weilbaecher

Oncotarget 2017 Sep 27;8(41):69250-69263. Epub 2017 Aug 27.

Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, MO, USA.

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September 2017

Bone-Induced Expression of Integrin β3 Enables Targeted Nanotherapy of Breast Cancer Metastases.

Cancer Res 2017 11 30;77(22):6299-6312. Epub 2017 Aug 30.

Department of Medicine, Division of Molecular Oncology, Washington University School of Medicine, St. Louis, Missouri.

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November 2017

Evaluating Acetate Metabolism for Imaging and Targeting in Multiple Myeloma.

Authors:

Francesca Fontana Xia Ge Xinming Su Deep Hathi Jingyu Xiang Simone Cenci Roberto Civitelli Kooresh I Shoghi Walter J Akers Andre D'avignon Katherine N Weilbaecher Monica Shokeen

Clin Cancer Res 2017 Jan 2;23(2):416-429. Epub 2016 Aug 2.

Department of Radiology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri.

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January 2017

Antagonizing Integrin β3 Increases Immunosuppression in Cancer.

Cancer Res 2016 06 23;76(12):3484-95. Epub 2016 May 23.

Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri.

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June 2016

Stromal-Initiated Changes in the Bone Promote Metastatic Niche Development.

Authors:

Xianmin Luo Yujie Fu Andrew J Loza Bhavna Murali Kathleen M Leahy Megan K Ruhland Margery Gang Xinming Su Ali Zamani Yu Shi Kory J Lavine David M Ornitz Katherine N Weilbaecher Fanxin Long Deborah V Novack Roberta Faccio Gregory D Longmore Sheila A Stewart

Cell Rep 2016 Jan 24;14(1):82-92. Epub 2015 Dec 24.

Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO 63110, USA; ICCE Institute, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address:

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January 2016