Katherine M Aird

Katherine M Aird

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Katherine M Aird

Katherine M Aird

Publications by authors named "Katherine M Aird"

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p16: cycling off the beaten path.

Mol Cell Oncol 2019 15;6(6):e1677140. Epub 2019 Oct 15.

Department of Cellular & Molecular Physiology, Penn State College of Medicine, Hershey, PA, USA.

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http://dx.doi.org/10.1080/23723556.2019.1677140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816386PMC
October 2019

Targeting IDH1 as a Prosenescent Therapy in High-grade Serous Ovarian Cancer.

Mol Cancer Res 2019 08 20;17(8):1710-1720. Epub 2019 May 20.

Department of Cellular & Molecular Physiology, Penn State College of Medicine, Hershey, Pennsylvania.

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http://mcr.aacrjournals.org/lookup/doi/10.1158/1541-7786.MCR
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http://dx.doi.org/10.1158/1541-7786.MCR-18-1233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679739PMC
August 2019

GPx3 supports ovarian cancer progression by manipulating the extracellular redox environment.

Redox Biol 2019 07 17;25:101051. Epub 2018 Nov 17.

Department of Pharmacology, Pennsylvania State University College of Medicine, Hershey, PA, USA; Department of Obstetrics and Gynecology, Pennsylvania State University College of Medicine, Hershey, PA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22132317183089
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http://dx.doi.org/10.1016/j.redox.2018.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859581PMC
July 2019

Simultaneous isotope dilution quantification and metabolic tracing of deoxyribonucleotides by liquid chromatography high resolution mass spectrometry.

Anal Biochem 2019 03 31;568:65-72. Epub 2018 Dec 31.

AJ Drexel Autism Institute, Drexel University, 3020 Market St Suite 560, Philadelphia, PA, 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ab.2018.12.023DOI Listing
March 2019

Jumonji C Demethylases in Cellular Senescence.

Genes (Basel) 2019 01 9;10(1). Epub 2019 Jan 9.

Department of Cellular & Molecular Physiology, Penn Stage College of Medicine, Hershey, PA 17033, USA.

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http://dx.doi.org/10.3390/genes10010033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356615PMC
January 2019

Deoxyribonucleotide Triphosphate Metabolism in Cancer and Metabolic Disease.

Front Endocrinol (Lausanne) 2018 18;9:177. Epub 2018 Apr 18.

Department of Cellular and Molecular Physiology, Penn State College of Medicine, Hershey, PA, United States.

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http://dx.doi.org/10.3389/fendo.2018.00177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915462PMC
April 2018

Ovarian cancer: how can resistance to chemotherapy be tackled?

Future Oncol 2017 12 28;13(30):2737-2739. Epub 2017 Nov 28.

Department of Cellular & Molecular Physiology, Penn State College of Medicine, Hershey, PA 17033, USA.

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http://dx.doi.org/10.2217/fon-2017-0235DOI Listing
December 2017

Ataxia-Telangiectasia Mutated Modulation of Carbon Metabolism in Cancer.

Front Oncol 2017 29;7:291. Epub 2017 Nov 29.

Department of Cellular and Molecular Physiology, Penn State College of Medicine, Hershey, PA, United States.

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http://dx.doi.org/10.3389/fonc.2017.00291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712564PMC
November 2017

Targeting RRM2 and Mutant BRAF Is a Novel Combinatorial Strategy for Melanoma.

Mol Cancer Res 2016 09 13;14(9):767-75. Epub 2016 Jun 13.

Gene Expression and Regulation Program, The Wistar Institute, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1541-7786.MCR-16-0099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025362PMC
September 2016

Metabolic alterations accompanying oncogene-induced senescence.

Mol Cell Oncol 2014 Jul-Sep;1(3):e963481. Epub 2014 Dec 23.

The Wistar Institute; Gene Expression and Regulation ; Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.4161/23723548.2014.963481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904889PMC
June 2016

Epigenetic synthetic lethality in ovarian clear cell carcinoma: EZH2 and ARID1A mutations.

Mol Cell Oncol 2016 Jan 14;3(1):e1032476. Epub 2015 Apr 14.

Gene Expression and Regulation, The Wistar Institute ; Philadelphia, PA USA.

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http://dx.doi.org/10.1080/23723556.2015.1032476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845188PMC
January 2016

EglN2 associates with the NRF1-PGC1α complex and controls mitochondrial function in breast cancer.

EMBO J 2015 Dec 22;34(23):2953-70. Epub 2015 Oct 22.

Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC, USA

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http://dx.doi.org/10.15252/embj.201591437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687683PMC
December 2015

SPOP E3 Ubiquitin Ligase Adaptor Promotes Cellular Senescence by Degrading the SENP7 deSUMOylase.

Cell Rep 2015 Nov 29;13(6):1183-1193. Epub 2015 Oct 29.

Gene Expression and Regulation Program, The Wistar Institute, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.09.083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644472PMC
November 2015

PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion.

Proc Natl Acad Sci U S A 2015 Jul 29;112(28):8638-43. Epub 2015 Jun 29.

Prostate Cancer Discovery and Development Program, The Wistar Institute, Philadelphia, PA 19104; Tumor Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, PA 19104;

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http://dx.doi.org/10.1073/pnas.1500722112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507184PMC
July 2015

ATM in senescence.

Oncotarget 2015 Jun;6(17):14729-30

Gene Expression and Regulation, The Wistar Institute, Philadelphia, PA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558108PMC
http://dx.doi.org/10.18632/oncotarget.4411DOI Listing
June 2015

ATM couples replication stress and metabolic reprogramming during cellular senescence.

Cell Rep 2015 May 30;11(6):893-901. Epub 2015 Apr 30.

Gene Expression and Regulation Program, The Wistar Institute, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431925PMC
May 2015

Nucleotide metabolism, oncogene-induced senescence and cancer.

Cancer Lett 2015 Jan 29;356(2 Pt A):204-10. Epub 2014 Jan 29.

Gene Expression and Regulation Program, The Wistar Institute Cancer Center, The Wistar Institute, Philadelphia, PA 19104, United States. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2014.01.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115046PMC
January 2015

Identification of ribonucleotide reductase M2 as a potential target for pro-senescence therapy in epithelial ovarian cancer.

Cell Cycle 2014 29;13(2):199-207. Epub 2013 Oct 29.

Gene Expression and Regulation Program; The Wistar Institute Cancer Center; The Wistar Institute; Philadelphia, PA USA.

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http://dx.doi.org/10.4161/cc.26953DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906237PMC
November 2014

Detection of senescence-associated heterochromatin foci (SAHF).

Methods Mol Biol 2013 ;965:185-96

Women's Cancer Program, Epigenetics and Progenitor Cells Keystone Program, Fox Chase Cancer Center, Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/978-1-62703-239-1_12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552318PMC
June 2013

RAS, cellular senescence and transformation: the BRCA1 DNA repair pathway at the crossroads.

Small GTPases 2012 Jul-Sep;3(3):163-7. Epub 2012 Jul 1.

Women's Cancer Program and Epigenetics and Progenitor Cell Keystone Program, Fox Chase Cancer Center, Philadelphia, PA, USA.

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http://www.tandfonline.com/doi/abs/10.4161/sgtp.19884
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http://dx.doi.org/10.4161/sgtp.19884DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442802PMC
April 2013

Suppression of nucleotide metabolism underlies the establishment and maintenance of oncogene-induced senescence.

Cell Rep 2013 Apr 4;3(4):1252-65. Epub 2013 Apr 4.

Gene Expression and Regulation Program, The Wistar Institute Cancer Center, The Wistar Institute, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.celrep.2013.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840499PMC
April 2013

Cellular uptake of neutral phosphorodiamidate morpholino oligomers.

Curr Pharm Biotechnol 2009 Sep 1;10(6):579-88. Epub 2009 Sep 1.

Department of Surgery, Comprehensive Cancer Center, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.2174/138920109789069279DOI Listing
September 2009