Katherine Luzuriaga

Katherine Luzuriaga

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Katherine Luzuriaga

Katherine Luzuriaga

Publications by authors named "Katherine Luzuriaga"

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The HIV-1 antibody response: a footprint of the viral reservoir in children vertically infected with HIV.

Lancet HIV 2020 May;7(5):e359-e365

Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, USA; Center for Clinical and Translational Science, University of Massachusetts Medical School, Worcester, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/S2352-3018(20)30100-4DOI Listing
May 2020

JITA: A Platform for Enabling Real Time Point-of-Care Patient Recruitment.

AMIA Jt Summits Transl Sci Proc 2020 30;2020:355-359. Epub 2020 May 30.

University of Massachusetts Medical School, Worcester, MA 01655, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233033PMC
May 2020

CDR3α drives selection of the immunodominant Epstein Barr virus (EBV) BRLF1-specific CD8 T cell receptor repertoire in primary infection.

PLoS Pathog 2019 11 25;15(11):e1008122. Epub 2019 Nov 25.

Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1008122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901265PMC
November 2019

No detection of CD4-independent human immunodeficiency virus 1 envelope glycoproteins in brain tissue of patients with or without neurological complications.

Arch Virol 2019 Feb 10;164(2):473-482. Epub 2018 Nov 10.

Biotech 2, Program in Molecular Medicine, University of Massachusetts Medical School, Suite 315, 373 Plantation Street, Worcester, MA, 01605, USA.

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http://dx.doi.org/10.1007/s00705-018-4094-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369005PMC
February 2019

Unique influenza A cross-reactive memory CD8 T-cell receptor repertoire has a potential to protect against EBV seroconversion.

J Allergy Clin Immunol 2017 10 16;140(4):1206-1210. Epub 2017 Jun 16.

Department of Pathology, University of Massachusetts Medical School, Worcester, Mass; Immunology and Microbiology Program, University of Massachusetts Medical School, Worcester, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.05.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669360PMC
October 2017

Early Combination Antiretroviral Therapy Limits HIV-1 Persistence in Children.

Annu Rev Med 2016 ;67:201-13

Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605; email:

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http://dx.doi.org/10.1146/annurev-med-091114-111159DOI Listing
October 2016

Treatment interruption after early-treated perinatal HIV-1 infection.

AIDS 2016 09;30(15):2381-3

aMolecular Medicine, University of Massachusetts Medical School, Worcester, MA, USA bPediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1097/QAD.0000000000001226DOI Listing
September 2016

Eliminating Pediatric HIV-1 Infection.

N Engl J Med 2016 07;375(2):193-4

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http://dx.doi.org/10.1056/NEJMc1604016DOI Listing
July 2016

Challenges in the Elimination of Pediatric HIV-1 Infection.

N Engl J Med 2016 Feb;374(8):761-70

From the Program in Molecular Medicine, University of Massachusetts Medical School, Worcester (K.L.); and the Elizabeth Glaser Pediatric AIDS Foundation, Washington, DC (L.M.M.).

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http://dx.doi.org/10.1056/NEJMra1505256DOI Listing
February 2016

Recombination elevates the effective evolutionary rate and facilitates the establishment of HIV-1 infection in infants after mother-to-child transmission.

Retrovirology 2015 Nov 16;12:96. Epub 2015 Nov 16.

Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, 87545, NM, USA.

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http://dx.doi.org/10.1186/s12977-015-0222-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647327PMC
November 2015

Very early combination antiretroviral therapy in infants: prospects for cure.

Curr Opin HIV AIDS 2015 Jan;10(1):4-11

aDepartment of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland bProgram in Molecular Medicine, Department of Pediatrics, and Center for Clinical and Translational Science, University of Massachusetts Medical School, Worcester, Massachusetts, USA.

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http://dx.doi.org/10.1097/COH.0000000000000127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351817PMC
January 2015

Influence of age at virologic control on peripheral blood human immunodeficiency virus reservoir size and serostatus in perinatally infected adolescents.

JAMA Pediatr 2014 Dec;168(12):1138-46

Program in Molecular Medicine, Department of Pediatrics, University of Massachusetts Medical School, Worcester10Center for Clinical and Translational Science, University of Massachusetts Medical School, Worcester.

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http://dx.doi.org/10.1001/jamapediatrics.2014.1560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324476PMC
December 2014

Absence of HIV-1 after treatment cessation in an infant.

N Engl J Med 2014 02;370(7):678

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http://dx.doi.org/10.1056/NEJMc1315498DOI Listing
February 2014

Absence of detectable HIV-1 viremia after treatment cessation in an infant.

N Engl J Med 2013 Nov 23;369(19):1828-35. Epub 2013 Oct 23.

From the Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore (D.P., C.Z., Y.H.C.), Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Frederick (M.P.), and the Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda (T.-W.C.) - all in Maryland; the Department of Pediatrics, University of Mississippi Medical Center, Jackson (H.G.); the University of California San Diego, La Jolla, and the Veterans Affairs San Diego Healthcare System, San Diego (M.S., D.R.); and the Department of Pediatrics, Program in Molecular Medicine, and Center for Clinical and Translational Science, University of Massachusetts Medical School, Worcester (K.L.).

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http://www.nejm.org/doi/10.1056/NEJMoa1302976
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http://dx.doi.org/10.1056/NEJMoa1302976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954754PMC
November 2013

Persistence of Epstein-Barr virus in self-reactive memory B cells.

J Virol 2012 Nov 5;86(22):12330-40. Epub 2012 Sep 5.

Department of Pathology, Tufts University School of Medicine, Boston, Massachusetts, USA.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.01699-12
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http://dx.doi.org/10.1128/JVI.01699-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486485PMC
November 2012

Pilot study on the immunogenicity of paired Env immunogens from mother-to-child transmitted HIV-1 isolates.

Hum Vaccin Immunother 2012 Nov 1;8(11):1638-47. Epub 2012 Nov 1.

Department of Medicine; University of Massachusetts Medical School; Worcester, MA, USA.

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http://dx.doi.org/10.4161/hv.22414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601138PMC
November 2012

Genotypic and functional properties of early infant HIV-1 envelopes.

Retrovirology 2011 Aug 15;8:67. Epub 2011 Aug 15.

Graduate School of Biomedical Sciences, University of Massachusetts Medical School, Worcester, MA, USA.

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http://dx.doi.org/10.1186/1742-4690-8-67DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189118PMC
August 2011

Broad cross-reactive TCR repertoires recognizing dissimilar Epstein-Barr and influenza A virus epitopes.

J Immunol 2010 Dec 3;185(11):6753-64. Epub 2010 Nov 3.

Department of Pathology and Program in Immunology and Virology, University of Massachusetts Medical School, Worcester, MA 01655, USA.

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http://dx.doi.org/10.4049/jimmunol.1000812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738202PMC
December 2010

Impaired generation of hepatitis B virus-specific memory B cells in HIV infected individuals following vaccination.

Vaccine 2010 May 28;28(21):3672-8. Epub 2010 Mar 28.

Department of Pediatrics and Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, United States.

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http://linkinghub.elsevier.com/retrieve/pii/S0264410X1000358
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http://dx.doi.org/10.1016/j.vaccine.2010.03.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862082PMC
May 2010

Infectious mononucleosis.

N Engl J Med 2010 May;362(21):1993-2000

Department of Pediatrics and Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.

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http://dx.doi.org/10.1056/NEJMcp1001116DOI Listing
May 2010

Low-cost HIV-1 diagnosis and quantification in dried blood spots by real time PCR.

PLoS One 2009 Jun 5;4(6):e5819. Epub 2009 Jun 5.

Department of Pediatrics and Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0005819PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688035PMC
June 2009

On the dynamics of acute EBV infection and the pathogenesis of infectious mononucleosis.

Blood 2008 Feb 8;111(3):1420-7. Epub 2007 Nov 8.

Department of Pathology, Tufts University School of Medicine, Boston, MA 02111, USA.

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http://dx.doi.org/10.1182/blood-2007-06-093278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2214734PMC
February 2008

Identification and characterization of HIV-1 CD8+ T cell escape variants with impaired fitness.

J Infect Dis 2008 Jan;197(2):300-8

Department of Pediatrics and Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.

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http://dx.doi.org/10.1086/524845DOI Listing
January 2008

Variation in HIV-1 R5 macrophage-tropism correlates with sensitivity to reagents that block envelope: CD4 interactions but not with sensitivity to other entry inhibitors.

Retrovirology 2008 Jan 18;5. Epub 2008 Jan 18.

Center for AIDS Research, Program in Molecular Medicine and Department of Molecular Genetics and Microbiology, 373 Plantation Street, University of Massachusetts Medical School, Worcester, MA 01605, USA.

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http://dx.doi.org/10.1186/1742-4690-5-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268948PMC
January 2008

Population pharmacokinetics of lamivudine in human immunodeficiency virus-exposed and -infected infants.

Antimicrob Agents Chemother 2007 Dec 24;51(12):4297-302. Epub 2007 Sep 24.

Division of Pharmacology and Drug Discovery, Pediatric Pharmacology Research Unit, University of California San Diego, MC 8214, San Diego, CA 92103-8214, USA.

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http://dx.doi.org/10.1128/AAC.00332-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2168008PMC
December 2007

Mother-to-child transmission of HIV: a global perspective.

Curr Infect Dis Rep 2007 Nov;9(6):511-7

University of Massachusetts Medical School, Department of Pediatrics and Program in Molecular Medicine, 373 Plantation Street, Suite 318, Worcester, MA 01605, USA.

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http://dx.doi.org/10.1007/s11908-007-0076-2DOI Listing
November 2007

Influence of EBV on the peripheral blood memory B cell compartment.

J Immunol 2007 Sep;179(5):3153-60

Department of Pathology, Jaharis Building, Tufts University School of Medicine, 150 Harrison Avenue, Boston, MA 02111, USA.

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http://www.jimmunol.org/content/179/5/3153.full.pdf
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http://dx.doi.org/10.4049/jimmunol.179.5.3153DOI Listing
September 2007

Virologic response to potent antiretroviral therapy and modeling of HIV dynamics in early pediatric infection.

J Infect Dis 2007 Jul 24;196(1):23-9. Epub 2007 May 24.

Department of Pediatrics, University of Medicine and Dentistry-New Jersey Medical School, Newark, NJ, USA.

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http://dx.doi.org/10.1086/518508DOI Listing
July 2007

Cytomegalovirus (CMV) IE1- and pp65-specific CD8+ T cell responses broaden over time after primary CMV infection in infants.

J Infect Dis 2007 Jun 8;195(12):1789-98. Epub 2007 May 8.

Department of Pediatrics, University of Massachusetts Medical School, Worcester, MA 01605, and Department of Pediatrics, Baystate Children's Hospital, Springfield, USA.

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http://dx.doi.org/10.1086/518042DOI Listing
June 2007

Vaccines to prevent transmission of HIV-1 via breastmilk: scientific and logistical priorities.

Lancet 2006 Aug;368(9534):511-21

University of Massachusetts Medical School, Program in Molecular Medicine, 373 Plantation Street, Suite 318, Worcester, MA 01605, USA.

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http://dx.doi.org/10.1016/S0140-6736(06)69159-9DOI Listing
August 2006

Cross-reactive influenza virus-specific CD8+ T cells contribute to lymphoproliferation in Epstein-Barr virus-associated infectious mononucleosis.

J Clin Invest 2005 Dec 23;115(12):3602-12. Epub 2005 Nov 23.

Department of Pathology, Program in Immunology and Virology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA.

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http://dx.doi.org/10.1172/JCI25078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1288832PMC
December 2005

Peripheral B cells latently infected with Epstein-Barr virus display molecular hallmarks of classical antigen-selected memory B cells.

Proc Natl Acad Sci U S A 2005 Dec 5;102(50):18093-8. Epub 2005 Dec 5.

Department of Pathology, Tufts University School of Medicine, Boston, MA 02111, USA.

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http://dx.doi.org/10.1073/pnas.0509311102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1306799PMC
December 2005

HIV-1-specific CD8+ T cell responses and viral evolution in women and infants.

J Immunol 2005 Nov;175(10):6976-86

Department of Pediatrics/Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.

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http://dx.doi.org/10.4049/jimmunol.175.10.6976DOI Listing
November 2005

Prevention of mother-to-child transmission of HIV infection.

Clin Infect Dis 2005 Feb 7;40(3):466-7. Epub 2005 Jan 7.

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http://dx.doi.org/10.1086/427294DOI Listing
February 2005

A trial of three antiretroviral regimens in HIV-1-infected children.

N Engl J Med 2004 Jun;350(24):2471-80

Department of Pediatrics and Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Mass 01605, USA.

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http://dx.doi.org/10.1056/NEJMoa032706DOI Listing
June 2004

Immunoprophylaxis to prevent mother-to-child transmission of HIV-1.

J Acquir Immune Defic Syndr 2004 Feb;35(2):169-77

Elizabeth Glaser Pediatric AIDS Foundation, David Geffen School of Medicine, University of California, Los Angeles, USA.

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http://dx.doi.org/10.1097/00126334-200402010-00012DOI Listing
February 2004

Demonstration of the Burkitt's lymphoma Epstein-Barr virus phenotype in dividing latently infected memory cells in vivo.

Proc Natl Acad Sci U S A 2004 Jan 19;101(1):239-44. Epub 2003 Dec 19.

Department of Pathology, Tufts University School of Medicine, Jaharis Building, 150 Harrison Avenue, Boston, MA 02111, USA.

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http://dx.doi.org/10.1073/pnas.2237267100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC314169PMC
January 2004

Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus.

Nature 2003 Nov;426(6965):450-4

Partners AIDS Research Center, Brigham and Women's Hospital, Department of Medicine (Microbiology and Molecular Genetics), Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nature02145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095016PMC
November 2003

HIV-1 replication increases HIV-specific CD4+ T cell frequencies but limits proliferative capacity in chronically infected children.

J Immunol 2003 Jun;170(11):5786-92

Graduate Program in Immunology/Virology and Department of Pediatrics, University of Massachusetts Medical School, Worcester, MA 01605, USA.

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http://dx.doi.org/10.4049/jimmunol.170.11.5786DOI Listing
June 2003

Differential kinetics and specificity of EBV-specific CD4+ and CD8+ T cells during primary infection.

J Immunol 2003 Mar;170(5):2590-8

Graduate Program in Immunology/Virology, University of Massachusetts Medical School, Worcester, MA 01605, USA.

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http://dx.doi.org/10.4049/jimmunol.170.5.2590DOI Listing
March 2003

Evidence for a cytopathogenicity determinant in HIV-1 Vpr.

Proc Natl Acad Sci U S A 2002 Jul 1;99(14):9503-8. Epub 2002 Jul 1.

Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA.

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http://dx.doi.org/10.1073/pnas.142313699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC123170PMC
July 2002

Pediatric HIV-1 infection: advances and remaining challenges.

AIDS Rev 2002 Jan-Mar;4(1):21-6

University of Massachusetts Medical School, Department of Pediatrics, Program in Molecular Medicine, 373 Plantation Street, Biotech II-Suite 318, Worcester, MA 01605, USA.

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June 2002

Enhanced culture method for detection of replication-competent virus in peripheral blood mononuclear cells of HIV type 1-infected individuals.

AIDS Res Hum Retroviruses 2002 May;18(8):577-83

Department of Pediatrics and Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605.

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http://dx.doi.org/10.1089/088922202753747923DOI Listing
May 2002

Phenotypic and functional heterogeneity of EBV epitope-specific CD8+ T cells.

J Immunol 2002 Apr;168(8):4184-91

Department of Pediatrics and Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.

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http://dx.doi.org/10.4049/jimmunol.168.8.4184DOI Listing
April 2002