Publications by authors named "Katherine L B Borden"

80Publications

The eukaryotic translation initiation factor eIF4E elevates steady-state mG capping of coding and noncoding transcripts.

Proc Natl Acad Sci U S A 2020 Oct 14;117(43):26773-26783. Epub 2020 Oct 14.

Institute of Research in Immunology and Cancer, Department of Pathology and Cell Biology, Université de Montréal, Montréal, QC H3T 1J4, Canada;

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http://dx.doi.org/10.1073/pnas.2002360117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604501PMC
October 2020

The diversity, plasticity, and adaptability of cap-dependent translation initiation and the associated machinery.

RNA Biol 2020 09 4;17(9):1239-1251. Epub 2020 Jun 4.

Institute of Research in Immunology and Cancer (IRIC), Department of Pathology and Cell Biology, Université de Montréal , Montreal, Québec, Canada.

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http://dx.doi.org/10.1080/15476286.2020.1766179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549709PMC
September 2020

Structural studies of the eIF4E-VPg complex reveal a direct competition for capped RNA: Implications for translation.

Proc Natl Acad Sci U S A 2019 11 11;116(48):24056-24065. Epub 2019 Nov 11.

Institute of Research in Immunology and Cancer, Department of Pathology and Cell Biology, Université de Montréal, Pavilion Marcelle-Coutu, Chemin Polytechnique, Montréal, QC H3T 1J4, Canada;

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http://dx.doi.org/10.1073/pnas.1904752116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883836PMC
November 2019

Nuclear eIF4E Stimulates 3'-End Cleavage of Target RNAs.

Cell Rep 2019 04;27(5):1397-1408.e4

Institute of Research in Immunology and Cancer (IRIC), Department of Pathology and Cell Biology, Université de Montréal, Pavillon Marcelle-Coutu, 2950 Chemin de Polytechnique, Montreal, QC H3T 1J4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661904PMC
April 2019

CDK9 and mTOR: trading places.

Blood 2019 03;133(11):1167-1168

Université de Montréal.

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http://dx.doi.org/10.1182/blood-2019-01-895086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418479PMC
March 2019

GLI1-Inducible Glucuronidation Targets a Broad Spectrum of Drugs.

ACS Chem Biol 2019 03 19;14(3):348-355. Epub 2019 Feb 19.

Institute for Research in Immunology and Cancer and Department of Pathology and Cell Biology , Université de Montréal , Montréal , Quebec , Canada.

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http://dx.doi.org/10.1021/acschembio.8b01118DOI Listing
March 2019

Biochemical and Structural Insights into the Eukaryotic Translation Initiation Factor eIF4E.

Curr Protein Pept Sci 2019 ;20(6):525-535

Institute for Research in Immunology and Cancer (IRIC), Department of Pathology and Cell Biology, Universite de Montreal, Pavillion Marcelle-Coutu, Chemin Polytechnique, Montreal, Quebec, Canada.

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http://www.eurekaselect.com/168847/article
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http://dx.doi.org/10.2174/1389203720666190110142438DOI Listing
August 2019

The Impact of Post-transcriptional Control: Better Living Through RNA Regulons.

Front Genet 2018 5;9:512. Epub 2018 Nov 5.

Institute for Research in Immunology and Cancer, Department of Pathology and Cell Biology, University of Montreal, Montreal, QC, Canada.

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https://www.frontiersin.org/article/10.3389/fgene.2018.00512
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http://dx.doi.org/10.3389/fgene.2018.00512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230556PMC
November 2018

Overcoming Drug Resistance through the Development of Selective Inhibitors of UDP-Glucuronosyltransferase Enzymes.

J Mol Biol 2019 01 11;431(2):258-272. Epub 2018 Nov 11.

Institute of Research in Immunology and Cancer (IRIC), Department of Pathology and Cell Biology, Université de Montréal, Pavilion Marcelle-Coutu, Chemin Polytechnique, Montreal, QC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2018.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331242PMC
January 2019

Chemical shift assignment of the viral protein genome-linked (VPg) from potato virus Y.

Biomol NMR Assign 2019 04 21;13(1):9-13. Epub 2018 Sep 21.

Department of Pathology and Cell Biology, Institute of Research in Immunology and Cancer (IRIC), Université de Montréal, Pavilion Marcelle-Coutu, Chemin Polytechnique, Montreal, QC, Canada.

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http://dx.doi.org/10.1007/s12104-018-9842-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428624PMC
April 2019

BRAF/MAPK and GSK3 signaling converges to control MITF nuclear export.

Proc Natl Acad Sci U S A 2018 09 27;115(37):E8668-E8677. Epub 2018 Aug 27.

Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Headington, OX3 7DQ Oxford, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1810498115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140509PMC
September 2018

A TFEB nuclear export signal integrates amino acid supply and glucose availability.

Nat Commun 2018 07 11;9(1):2685. Epub 2018 Jul 11.

Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Headington, Oxford, OX3 7DQ, UK.

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http://dx.doi.org/10.1038/s41467-018-04849-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041281PMC
July 2018

Backbone assignment of the apo-form of the human C-terminal domain of UDP-glucuronosyltransferase 1A (UGT1A).

Biomol NMR Assign 2018 10 22;12(2):315-318. Epub 2018 Jun 22.

Department of Pathology and Cell Biology, Institute of Research in Immunology and Cancer (IRIC), Université de Montréal, Pavilion Marcelle-Coutu, Chemin Polytechnique, Montreal, QC, Canada.

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http://dx.doi.org/10.1007/s12104-018-9830-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309593PMC
October 2018

A biochemical framework for eIF4E-dependent mRNA export and nuclear recycling of the export machinery.

RNA 2017 06 21;23(6):927-937. Epub 2017 Mar 21.

Institute of Research in Immunology and Cancer (IRIC), Department of Pathology and Cell Biology, Université de Montréal, Pavillon Marcelle-Coutu, Chemin de Polytechnique, Montreal, Québec, H3T 1J4, Canada.

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http://dx.doi.org/10.1261/rna.060137.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435865PMC
June 2017

The eukaryotic translation initiation factor eIF4E wears a "cap" for many occasions.

Translation (Austin) 2016 10;4(2):e1220899. Epub 2016 Aug 10.

Department of Pathology and Cell Biology, Institute of Research in Immunology and Cancer (IRIC), Université de Montréal , Montreal, Québec, Canada.

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http://dx.doi.org/10.1080/21690731.2016.1220899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173310PMC
August 2016

Importin 8 mediates m7G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E.

Proc Natl Acad Sci U S A 2016 May 25;113(19):5263-8. Epub 2016 Apr 25.

Institute of Research in Immunology and Cancer, Department of Pathology and Cell Biology, Université de Montréal, Montreal, QC, H3T 1J4, Canada;

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http://dx.doi.org/10.1073/pnas.1524291113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868427PMC
May 2016

Multiple Export Mechanisms for mRNAs.

Cells 2015 Aug 28;4(3):452-73. Epub 2015 Aug 28.

Department of Pathology and Cell Biology, Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, QC, H3C 3J7, Canada.

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http://dx.doi.org/10.3390/cells4030452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588045PMC
August 2015

Molecular Pathways: GLI1-Induced Drug Glucuronidation in Resistant Cancer Cells.

Clin Cancer Res 2015 May 25;21(10):2207-10. Epub 2015 Mar 25.

Institute of Research in Immunology and Cancer (IRIC), Department of Pathology and Cell Biology, Université de Montréal, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-1370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433783PMC
May 2015

The eukaryotic translation initiation factor eIF4E in the nucleus: taking the road less traveled.

Immunol Rev 2015 Jan;263(1):210-23

Institute for Research in Immunology and Cancer & Dept. of Pathology and Cell Biology, Université de Montréal, Montréal, QC, Canada.

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http://dx.doi.org/10.1111/imr.12240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269245PMC
January 2015

When will resistance be futile?

Cancer Res 2014 Dec 4;74(24):7175-80. Epub 2014 Dec 4.

Department of Pathology and Cell Biology, Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Canada.

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http://cancerres.aacrjournals.org/content/early/2014/12/03/0
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-14-2607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268154PMC
December 2014

The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation.

Nature 2014 Jul 28;511(7507):90-3. Epub 2014 May 28.

Institute for Research in Immunology and Cancer and Department of Pathology and Cell Biology, Université de Montréal, P.O. Box 6128, Downtown Station, Montréal, Québec H3C 3J7, Canada.

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http://dx.doi.org/10.1038/nature13283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138053PMC
July 2014

Conformational changes induced in the eukaryotic translation initiation factor eIF4E by a clinically relevant inhibitor, ribavirin triphosphate.

Biochem Biophys Res Commun 2013 May 10;434(3):614-9. Epub 2013 Apr 10.

Institute of Research in Immunology and Cancer, Department of Pathology and Cell Biology, Université de Montréal, Pavilion Marcelle-Coutu, Chemin Polytechnique, Montreal, Qc, Canada H3T 1J4.

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http://dx.doi.org/10.1016/j.bbrc.2013.03.125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659399PMC
May 2013

Aiding and abetting cancer: mRNA export and the nuclear pore.

Trends Cell Biol 2013 Jul 10;23(7):328-35. Epub 2013 Apr 10.

Institute for Research in Immunology and Cancer (IRIC), Department of Pathology and Cell Biology, Université de Montréal, Pavillion Marcelle-Coutu, Chemin Polytechnique, Montréal, Québec H3T 1J4, Canada.

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http://dx.doi.org/10.1016/j.tcb.2013.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700650PMC
July 2013

Mechanisms and insights into drug resistance in cancer.

Front Pharmacol 2013 14;4:28. Epub 2013 Mar 14.

Department of Pathology and Cell Biology, Institute of Research in Immunology and Cancer, Université de Montréal Montreal, QC, Canada.

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http://journal.frontiersin.org/article/10.3389/fphar.2013.00
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http://dx.doi.org/10.3389/fphar.2013.00028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596793PMC
March 2013

The oncogene eIF4E: using biochemical insights to target cancer.

J Interferon Cytokine Res 2013 May 8;33(5):227-38. Epub 2013 Mar 8.

Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1089/jir.2012.0142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653383PMC
May 2013

eIF4E3 acts as a tumor suppressor by utilizing an atypical mode of methyl-7-guanosine cap recognition.

Proc Natl Acad Sci U S A 2013 Mar 19;110(10):3877-82. Epub 2013 Feb 19.

Institute for Research in Immunology and Cancer, Department of Pathology and Cell Biology, Université de Montréal, Montreal, QC, Canada H3T 1J4.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1216862110
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http://dx.doi.org/10.1073/pnas.1216862110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593863PMC
March 2013

The oncogene eIF4E reprograms the nuclear pore complex to promote mRNA export and oncogenic transformation.

Cell Rep 2012 Aug 16;2(2):207-15. Epub 2012 Aug 16.

Institute for Research in Immunology and Cancer, Department of Pathology and Cell Biology, Université de Montréal, Québec, Canada.

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http://dx.doi.org/10.1016/j.celrep.2012.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463940PMC
August 2012

RSK regulates activated BRAF signalling to mTORC1 and promotes melanoma growth.

Oncogene 2013 Jun 16;32(24):2917-2926. Epub 2012 Jul 16.

Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, Quebec H3C 3J7, Canada.

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http://dx.doi.org/10.1038/onc.2012.312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440665PMC
June 2013

The Development of Novel Therapies for the Treatment of Acute Myeloid Leukemia (AML).

Cancers (Basel) 2012 Nov 2;4(4):1161-79. Epub 2012 Nov 2.

Department of Medicine and Oncology, Segal Cancer Centre, Jewish General Hospital, Montreal, QC, H3T 1E2, Canada.

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http://dx.doi.org/10.3390/cancers4041161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712735PMC
November 2012

mRNA export and cancer.

Wiley Interdiscip Rev RNA 2012 Jan-Feb;3(1):13-25. Epub 2011 Jul 27.

Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Quebec, Canada.

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http://dx.doi.org/10.1002/wrna.101DOI Listing
April 2012

Cell biology. Puzzled by PML.

Science 2010 Nov;330(6008):1183-4

Institute of Research in Immunology and Cancer, Department of Pathology and Cell Biology, Université de Montréal, Pavillion Marcelle-Coutu, Chemin Polytechnique, Montreal, QC, Canada.

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http://dx.doi.org/10.1126/science.1199405DOI Listing
November 2010

Ribavirin as an anti-cancer therapy: acute myeloid leukemia and beyond?

Leuk Lymphoma 2010 Oct;51(10):1805-15

Institute of Research in Immunology and Cancer (IRIC), Department of Pathology and Cell Biology, Université de Montréal, Montreal, QC, Canada.

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http://dx.doi.org/10.3109/10428194.2010.496506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950216PMC
October 2010

Structural characterization of the Z RING-eIF4E complex reveals a distinct mode of control for eIF4E.

Proc Natl Acad Sci U S A 2010 Mar 8;107(12):5441-6. Epub 2010 Mar 8.

Institute of Research in Immunology and Cancer, Department of Pathology and Cell Biology, Université de Montréal, Pavillion Marcelle-Coutu, Chemin Polytechnique, Montreal, QC, Canada.

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http://dx.doi.org/10.1073/pnas.0909877107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851782PMC
March 2010

Two fundamentally distinct PCNA interaction peptides contribute to chromatin assembly factor 1 function.

Mol Cell Biol 2009 Dec 12;29(24):6353-65. Epub 2009 Oct 12.

Cancer Research UK, London Research Institute, London WC2A 3PX, United Kingdom.

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http://dx.doi.org/10.1128/MCB.01051-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786881PMC
December 2009

Control of p53 multimerization by Ubc13 is JNK-regulated.

Proc Natl Acad Sci U S A 2009 Aug 27;106(31):12676-81. Epub 2009 Jul 27.

Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Quebec, H3T 1J4, Canada.

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http://dx.doi.org/10.1073/pnas.0900596106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722327PMC
August 2009

Tissue targeting in cancer: eIF4E's tale.

Clin Cancer Res 2009 Jul 9;15(13):4254-5. Epub 2009 Jun 9.

Institute of Research in Immunology and Cancer (IRIC), Department of Pathology and Cell Biology, Université de Montréal, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-0552DOI Listing
July 2009

Perspectives in PML: a unifying framework for PML function.

Front Biosci (Landmark Ed) 2009 Jan 1;14:497-509. Epub 2009 Jan 1.

Institute for Research in Immunology and Cancer and Department of Pathology and Cell Biology, Universite de Montreal, Montreal, Quebec, H4M 1J6 Canada.

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http://dx.doi.org/10.2741/3258DOI Listing
January 2009

Molecular dissection of the eukaryotic initiation factor 4E (eIF4E) export-competent RNP.

EMBO J 2009 Apr 5;28(8):1087-98. Epub 2009 Mar 5.

Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Quebec, Canada.

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http://dx.doi.org/10.1038/emboj.2009.53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683702PMC
April 2009

Stability of eukaryotic translation initiation factor 4E mRNA is regulated by HuR, and this activity is dysregulated in cancer.

Mol Cell Biol 2009 Mar 29;29(5):1152-62. Epub 2008 Dec 29.

Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Québec H3T 1J4, Canada.

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http://dx.doi.org/10.1128/MCB.01532-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643828PMC
March 2009

NMR assignment of the arenaviral protein Z from Lassa fever virus.

Biomol NMR Assign 2008 Jun;2(1):81-4

Department of Pathology and Cell Biology, Institute of Research in Immunology and Cancer (IRIC), Université de Montréal, Pavilion Marcelle-Coutu, 2950 Chemin Polytechnique, Montreal, QC, Canada.

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http://link.springer.com/content/pdf/10.1007%2Fs12104-008-90
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http://link.springer.com/10.1007/s12104-008-9090-z
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http://dx.doi.org/10.1007/s12104-008-9090-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2574003PMC
June 2008

Ribavirin targets eIF4E dependent Akt survival signaling.

Biochem Biophys Res Commun 2008 Oct 14;375(3):341-5. Epub 2008 Aug 14.

Institute for Research in Immunology and Cancer, Department of Pathology and Cell Biology, Université de Montréal, Montréal, Que., Canada H4M 1J6.

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http://dx.doi.org/10.1016/j.bbrc.2008.07.163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573464PMC
October 2008

Pondering the puzzle of PML (promyelocytic leukemia) nuclear bodies: can we fit the pieces together using an RNA regulon?

Biochim Biophys Acta 2008 Nov 18;1783(11):2145-54. Epub 2008 Jun 18.

Institute for Research in Immunology and Cancer and Department of Pathology and Cell Biology, Université de Montréal, Montréal, Québec, Canada H4M 1J6.

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http://dx.doi.org/10.1016/j.bbamcr.2008.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652867PMC
November 2008

The eIF4E RNA regulon promotes the Akt signaling pathway.

J Cell Biol 2008 Apr;181(1):51-63

Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Québec H4M 1J6, Canada.

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http://dx.doi.org/10.1083/jcb.200707018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2287285PMC
April 2008

Controlling gene expression through RNA regulons: the role of the eukaryotic translation initiation factor eIF4E.

Cell Cycle 2007 Jan 11;6(1):65-9. Epub 2007 Jan 11.

Institute for Research in Immunology and Cancer, Department of Pathology and Cell Biology, Université de Montréal, Montréal, Québec, Canada.

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http://dx.doi.org/10.4161/cc.6.1.3688DOI Listing
January 2007

eIF4E is a central node of an RNA regulon that governs cellular proliferation.

J Cell Biol 2006 Nov 30;175(3):415-26. Epub 2006 Oct 30.

Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, Québec H4M 1J6, Canada.

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http://www.jcb.org/lookup/doi/10.1083/jcb.200607020
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http://dx.doi.org/10.1083/jcb.200607020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064519PMC
November 2006

Cap-free structure of eIF4E suggests a basis for conformational regulation by its ligands.

EMBO J 2006 Nov 12;25(21):5138-49. Epub 2006 Oct 12.

Department of Pathology and Cell Biology, Institute for Research in Immunology and Cancer, Université de Montréal, Pavillion Marcelle-Coutu, Chemin Polytechnique, Montréal, QC, Canada.

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http://dx.doi.org/10.1038/sj.emboj.7601380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1630411PMC
November 2006

Regulation of p53 localization and activity by Ubc13.

Mol Cell Biol 2006 Dec 25;26(23):8901-13. Epub 2006 Sep 25.

Signal Transduction Program, Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1128/MCB.01156-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636826PMC
December 2006

NMR assignment of human eukaryotic translation initiation factor 4E (eIF4E) in its cap-free form.

J Biomol NMR 2006 27;36 Suppl 1:65. Epub 2006 Jul 27.

Institute of Research in Immunology and Cancer (IRIC), Department of Pathology and Cell Biology, Université de Montréal, Pavilion Marcelle-Coutu, 2950 Chemin Polytechnique, Montreal, QC, Canada.

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http://dx.doi.org/10.1007/s10858-006-9051-8DOI Listing
August 2007

Arenavirus Z protein as an antiviral target: virus inactivation and protein oligomerization by zinc finger-reactive compounds.

J Gen Virol 2006 May;87(Pt 5):1217-1228

Laboratory of Virology, Department of Biological Chemistry, School of Sciences, University of Buenos Aires, Ciudad Universitaria, Pabellón 2, Piso 4, 1428 Buenos Aires, Argentina.

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http://dx.doi.org/10.1099/vir.0.81667-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423342PMC
May 2006

Further evidence that ribavirin interacts with eIF4E.

RNA 2005 Dec 26;11(12):1762-6. Epub 2005 Oct 26.

Mount Sinai School of Medicine, New York University, New York, NY 10029, USA.

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http://www.rnajournal.org/cgi/doi/10.1261/rna.2238705
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http://dx.doi.org/10.1261/rna.2238705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1370864PMC
December 2005

eIF4E promotes nuclear export of cyclin D1 mRNAs via an element in the 3'UTR.

J Cell Biol 2005 Apr 18;169(2):245-56. Epub 2005 Apr 18.

Institute for Research in Immunology and Cancer, University of Montreal, Quebec, Canada.

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http://dx.doi.org/10.1083/jcb.200501019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171863PMC
April 2005

Eukaryotic translation initiation factor 4E activity is modulated by HOXA9 at multiple levels.

Mol Cell Biol 2005 Feb;25(3):1100-12

Institute for Research in Immunovirology and Cancer, University of Montreal, Montreal, Quebec H3T 1J4, Canada.

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http://dx.doi.org/10.1128/MCB.25.3.1100-1112.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC544005PMC
February 2005

Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap.

Proc Natl Acad Sci U S A 2004 Dec 15;101(52):18105-10. Epub 2004 Dec 15.

Structural Biology Program, Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York University, New York, NY 10029, USA.

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http://dx.doi.org/10.1073/pnas.0406927102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC539790PMC
December 2004

Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities.

Cancer Res 2004 Dec;64(23):8639-42

Structural Biology Program, Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York University, New York, New York, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-2677DOI Listing
December 2004

Structure of the C-terminal RING finger from a RING-IBR-RING/TRIAD motif reveals a novel zinc-binding domain distinct from a RING.

J Mol Biol 2004 Jul;340(5):1117-29

Structural Biology Program, Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York University, New York, NY 10029, USA.

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http://dx.doi.org/10.1016/j.jmb.2004.05.035DOI Listing
July 2004

Physical mechanisms and biological significance of supramolecular protein self-assembly.

Curr Protein Pept Sci 2004 Apr;5(2):125-34

Structural Biology Program, Department of Physiology & Biophysics, Mount Sinai School of Medicine, New York University, New York, NY 10029, USA.

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http://dx.doi.org/10.2174/1389203043486856DOI Listing
April 2004

Aberrant eukaryotic translation initiation factor 4E-dependent mRNA transport impedes hematopoietic differentiation and contributes to leukemogenesis.

Mol Cell Biol 2003 Dec;23(24):8992-9002

Structural Biology Program, Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York University, One Gustave Levy Place, New York, NY 10029, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC309660PMC
http://dx.doi.org/10.1128/mcb.23.24.8992-9002.2003DOI Listing
December 2003

UV-C-induced DNA damage leads to p53-dependent nuclear trafficking of PML.

Oncogene 2003 Mar;22(11):1620-8

Laboratory of Human Carcinogenesis, CCR, National Cancer Institute, NIH, Bethesda, MD 20892-4255, USA.

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http://dx.doi.org/10.1038/sj.onc.1206140DOI Listing
March 2003

The proline-rich homeodomain protein, PRH, is a tissue-specific inhibitor of eIF4E-dependent cyclin D1 mRNA transport and growth.

EMBO J 2003 Feb;22(3):689-703

Structural Biology Program and Institute for Computational Biomedicine, Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York University, One Gustave Levy Place, New York, NY 10029, USA.

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http://dx.doi.org/10.1093/emboj/cdg069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC140753PMC
February 2003

Control of biochemical reactions through supramolecular RING domain self-assembly.

Proc Natl Acad Sci U S A 2002 Nov 18;99(24):15404-9. Epub 2002 Nov 18.

Structural Biology Program, Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York University, New York 10029, USA.

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http://dx.doi.org/10.1073/pnas.202608799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC137729PMC
November 2002

Gamma interferon and cadmium treatments modulate eukaryotic initiation factor 4E-dependent mRNA transport of cyclin D1 in a PML-dependent manner.

Mol Cell Biol 2002 Sep;22(17):6183-98

Structural Biology Program, Department of Physiology & Biophysics, Mount Sinai School of Medicine, New York University, New York, New York 10029, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC134012PMC
http://dx.doi.org/10.1128/mcb.22.17.6183-6198.2002DOI Listing
September 2002

Pondering the promyelocytic leukemia protein (PML) puzzle: possible functions for PML nuclear bodies.

Mol Cell Biol 2002 Aug;22(15):5259-69

Structural Biology Program, Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York University, One Gustave L. Levy Place, New York, NY 10029, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC133952PMC
http://dx.doi.org/10.1128/mcb.22.15.5259-5269.2002DOI Listing
August 2002

The emerging roles of translation factor eIF4E in the nucleus.

Differentiation 2002 Mar;70(1):10-22

Structural Biology Program, Department of Physiology & Biophysics, Mount Sinai School of Medicine, New York University, One Gustave Levy Place, New York, NY 10029, USA.

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http://dx.doi.org/10.1046/j.1432-0436.2002.700102.xDOI Listing
March 2002

Self-assembly properties of a model RING domain.

Proc Natl Acad Sci U S A 2002 Jan 15;99(2):667-72. Epub 2002 Jan 15.

Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York University, New York, NY 10029, USA.

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http://dx.doi.org/10.1073/pnas.012317299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC117363PMC
January 2002