Katherine J Aitchison

Katherine J Aitchison

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Katherine J Aitchison

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Trend level gene-gender interaction effect for the BDNF rs6265 variant on age of onset of psychosis.

Psychiatry Res 2019 Oct 8;280:112500. Epub 2019 Aug 8.

Department of Psychiatry and Medical Genetics, University of Alberta, Edmonton, AB, Canada; Edmonton Early Intervention in Psychosis Clinic, Edmonton, AB, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.psychres.2019.112500DOI Listing
October 2019

Effect of antidepressant switching between nortriptyline and escitalopram after a failed first antidepressant treatment among patients with major depressive disorder.

Br J Psychiatry 2019 Aug 30;215(2):494-501. Epub 2019 Jan 30.

Professor,Psychosis Research Unit,Aarhus University Hospital - Psychiatry;Department of Clinical Medicine,Aarhus University;and iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research,Denmark.

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http://dx.doi.org/10.1192/bjp.2018.302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624130PMC
August 2019

Trend level gene-gender interaction effect for the BDNF rs6265 variant on age of onset of psychosis.

Psychiatry Res 2019 Oct 8;280:112500. Epub 2019 Aug 8.

Department of Psychiatry and Medical Genetics, University of Alberta, Edmonton, AB, Canada; Edmonton Early Intervention in Psychosis Clinic, Edmonton, AB, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.psychres.2019.112500DOI Listing
October 2019

Genetic disposition to inflammation and response to antidepressants in major depressive disorder.

J Psychiatr Res 2018 10 7;105:17-22. Epub 2018 Aug 7.

Department of Pathology, Dalhousie University, Halifax, NS, Canada; Department of Psychiatry, Dalhousie University, Halifax, NS, Canada; Nova Scotia Health Authority, Halifax, NS, Canada; King's College London, Social, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychires.2018.08.011DOI Listing
October 2018

Antidepressant drug-specific prediction of depression treatment outcomes from genetic and clinical variables.

Sci Rep 2018 04 3;8(1):5530. Epub 2018 Apr 3.

Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, 16 De Crespigny Park, Denmark Hill, London, SE5 8AF, UK.

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http://dx.doi.org/10.1038/s41598-018-23584-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882876PMC
April 2018

Contribution of genes in the GABAergic pathway to bipolar disorder and its executive function deficit in the Chinese Han population.

Am J Med Genet B Neuropsychiatr Genet 2018 Jan 14;177(1):50-67. Epub 2017 Nov 14.

Psychiatric Laboratory and Mental Health Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, P.R. China.

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http://dx.doi.org/10.1002/ajmg.b.32601DOI Listing
January 2018

Implications of Cannabis Legalization on Youth and Young Adults.

Can J Psychiatry 2018 01;63(1):65-71

6 Professor, Department of Psychiatry and Adjunct Professor, Department of Medical Genetics, University of Alberta.

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http://dx.doi.org/10.1177/0706743718759031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788125PMC
January 2018

Interaction between the gene, body mass index and depression: meta-analysis of 13701 individuals.

Br J Psychiatry 2017 08 22;211(2):70-76. Epub 2017 Jun 22.

Margarita Rivera, PhD, Department of Biochemistry and Molecular Biology II and Institute of Neurosciences, Center for Biomedical Research, University of Granada, Granada, Spain, and MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, Kinǵs College London, UK; Adam E. Locke, PhD, Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA; Tanguy Corre, PhD, Department of Medical Genetics, University of Lausanne, Lausanne, and Swiss Institute of Bioinformatics, Lausanne, Switzerland; Darina Czamara, PhD, Christiane Wolf, PhD, Max Planck Institute of Psychiatry, Munich, Germany; Ana Ching-Lopez, Department of Psychiatry, School of Medicine, University of Granada, and Institute of Neurosciences Federico Olóriz, Centra de Investigación Biomédica, University of Granada, Spain; Yuri Milaneschi, PhD, Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center/GGZ in Geest, Amsterdam, The Netherlands; Stefan Kloiber, MD, Max Planck Institute of Psychiatry, Munich, Germany; Sara Cohen-Woods, PhD, School of Psychology, Flinders University, Adelaide, South Australia, Australia; James Rucker, MD, PhD, MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK; Katherine J. Aitchison, MD, PhD, Department of Psychiatry, University of Alberta, Alberta, Canada; Sven Bergmann, PhD, Department of Medical Genetics, University of Lausanne, Lausanne, and Swiss Institute of Bioinformatics, Lausanne, Switzerland; Dorret I. Boomsma, PhD, Department of Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands; Nick Craddock, MB, PhD, FMedSci, Department of Psychological Medicine and Neurology, Cardiff University School of Medicine, Henry Wellcome Building, Cardiff, UK; Michael Gill, MD, Department of Psychiatry, Trinity Centre for Health Sciences, Dublin 8, Ireland; Florian Holsboer, MD, PhD, Max Planck Institute of Psychiatry, Munich, Germany; Jouke-Jan Hottenga, PhD, Department of Psychiatry, University of Alberta, Alberta, Canada; Ania Korszun, PhD, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK; Zoltan Kutalik, PhD, Department of Medical Genetics, University of Lausanne, Lausanne, and Swiss Institute of Bioinformatics, Lausanne, Switzerland; Susanne Lucae, MD, PhD, Max Planck Institute of Psychiatry, Munich, Germany; Wolfgang Maier, MD, Department of Psychiatry, University of Bonn, Bonn, Germany; Ole Mors, MD, PhD, Research Department P, Aarhus University Hospital, Risskov, Denmark; Bertram Müller-Myhsok MD, Max Planck Institute of Psychiatry, Munich, Germany; Michael J. Owen, MB, PhD, FMedSci, MRC Centre for Neuropsychiatry Genetics and Genomics, Department of Psychological Medicine and Neurology, School of Medicine, Cardiff University, Cardiff, UK; Brenda W. J. H. Penninx, PhD, Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center/GGZ in Geest, Amsterdam, The Netherlands; Martin Preisig, MD, Department of Psychiatry, Lausanne University Hospital, 1008 Prilly-Lausanne, Switzerland; John Rice, PhD, Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA; Marcella Rietschel, MD, Central Institute of Mental Health, Mannheim, Germany; Federica Tozzi, MD, Genetics Division, Drug Discovery, GlaxoSmithKline Research and Development, Verona, Italy; Rudolf Uher, MD, PhD, MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK, and Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada; Peter Vollenweider, MD, PhD, Gerard Waeber, MD, PhD, Division of Internal Medicine, CHUV, Lausanne, Switzerland; Gonneke Willemsen, PhD, Department of Psychiatry, University of Alberta, Alberta, Canada; Ian W. Craig, PhD, Anne E. Farmer, MD, MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK; Cathryn M. Lewis, PhD, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, and Department of Medical and Molecular Genetics, School of Medicine, King's College London, UK; Gerome Breen, PhD, Peter McGuffin, MB, PhD, FMedSci, MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.

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http://dx.doi.org/10.1192/bjp.bp.116.183475DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537566PMC
August 2017

Association between C-reactive protein (CRP) with depression symptom severity and specific depressive symptoms in major depression.

Brain Behav Immun 2017 May 1;62:344-350. Epub 2017 Mar 1.

Aarhus University Hospital, Risskov, Psychosis Research Unit, Aarhus, Denmark; iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.

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http://dx.doi.org/10.1016/j.bbi.2017.02.020DOI Listing
May 2017

An Examination of Polygenic Score Risk Prediction in Individuals With First-Episode Psychosis.

Biol Psychiatry 2017 03 6;81(6):470-477. Epub 2016 Aug 6.

Medical Research Council, Social, Genetic & Developmental Psychiatry Centre; Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom; National Institute for Health Research Mental Health Biomedical Research Centre, South London and Maudsley National Health Service Foundation Trust and King's College London, London, United Kingdom.

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http://dx.doi.org/10.1016/j.biopsych.2016.06.028DOI Listing
March 2017

Combining clinical variables to optimize prediction of antidepressant treatment outcomes.

J Psychiatr Res 2016 07 1;78:94-102. Epub 2016 Apr 1.

Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, 16 De Crespigny Park, Denmark Hill, London, SE5 8AF, UK; Dalhousie University Department of Psychiatry, 5909 Veterans' Memorial Drive, Halifax, B3H 2E2, Nova Scotia, Canada.

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http://dx.doi.org/10.1016/j.jpsychires.2016.03.016DOI Listing
July 2016

Phenotypic Association Analyses With Copy Number Variation in Recurrent Depressive Disorder.

Biol Psychiatry 2016 Feb 25;79(4):329-36. Epub 2015 Feb 25.

Medical Research Council Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London, United Kingdom; National Institute for Health Research Biomedical Research Centre, South London and Maudsley National Health Service Foundation Trust and Institute of Psychiatry, King's College London.

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http://dx.doi.org/10.1016/j.biopsych.2015.02.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725574PMC
February 2016

Changes in biomarkers of bone turnover in an aripiprazole add-on or switching study.

Schizophr Res 2016 Feb 12;170(2-3):245-51. Epub 2016 Jan 12.

Department of Psychiatry, University of Alberta, Canada; COAST Team, South London and Maudsley NHS Foundation Trust, London, UK; Department of Medical Genetics, University of Alberta, Canada; Kings College London, MRC SGDP Centre, UK.

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http://dx.doi.org/10.1016/j.schres.2015.12.007DOI Listing
February 2016

Transcriptomics and the mechanisms of antidepressant efficacy.

Eur Neuropsychopharmacol 2016 Jan 12;26(1):105-112. Epub 2015 Nov 12.

King׳s College London, Institute of Psychiatry, King׳s Health Partners Centre for Neurodegeneration Research, London, UK; NIHR Biomedical Research Centre for Mental Health at South London and Maudsley NHS Foundation Trust and Institute of Psychiatry, King׳s College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.euroneuro.2015.10.009DOI Listing
January 2016

Authors' reply.

Br J Psychiatry 2015 Oct;207(4):363-4

Cynthia H.Y. Fu, School of Psychology, University of East London, Stratford Campus, Water Lane, London E15 4LZ, UK. Email: and Centre for Affective Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK; Rebecca MacGregor Legge, Centre for Affective Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK; Sarah Cohen-Woods, Discipline of Psychiatry, School of Medicine, University of Adelaide, Adelaide, Australia; James H. Cole, Computational, Cognitive and Clinical Neuroimaging Laboratory, Department of Medicine, Imperial College London, UK; Katherine J. Aitchison, Department of Psychiatry, University of Alberta, Edmonton, Canada; Peter McGuffin, MRC Social, Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.

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http://dx.doi.org/10.1192/bjp.207.4.363aDOI Listing
October 2015

Modulatory effects of brain-derived neurotrophic factor Val66Met polymorphism on prefrontal regions in major depressive disorder.

Br J Psychiatry 2015 May 5;206(5):379-84. Epub 2015 Mar 5.

Rebecca MacGregor Legge, MSc, Shahbaz Sendi, MD, Department of Psychological Medicine, Institute of Psychiatry, King's College London; James H. Cole, PhD, Computational, Cognitive and Clinical Neuroimaging Laboratory, Department of Medicine, Imperial College London, UK; Sarah Cohen-Woods, PhD, Discipline of Psychiatry, School of Medicine, University of Adelaide, Adelaide, Australia; Sergi G. Costafreda, MD, PhD, Department of Old Age Psychiatry, Institute of Psychiatry, King's College London; Andrew Simmons, PhD, Department of Neuroimaging, Institute of Psychiatry, National Institute of Health Research (NIHR) Biomedical Research Centre for Mental Health at South London and Department of Old Age Psychiatry, Institute of Psychiatry, King's College London; Anne E. Farmer, MD, FRCPsych, Medical Research Council (MRC) Social, Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, King's College London, UK; Katherine J. Aitchison, PhD, MRCPsych, Department of Psychiatry, University of Alberta, Edmonton, Canada; Peter McGuffin, PhD, FMedSci, NIHR Biomedical Research Centre for Mental Health at South London and Department of Old Age Psychiatry, Institute of Psychiatry, MRC Social, Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, King's College London; Cynthia H.Y. Fu, MD, PhD, Department of Psychological Medicine, Institute of Psychiatry, King's College London, and School of Psychology, University of East London, London, UK.

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https://www.cambridge.org/core/product/identifier/S000712500
Publisher Site
http://dx.doi.org/10.1192/bjp.bp.113.143529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416135PMC
May 2015

Association of KIBRA rs17070145 polymorphism with episodic memory in the early stages of a human neurodevelopmental disorder.

Psychiatry Res 2014 Dec 19;220(1-2):37-43. Epub 2014 Jul 19.

Institute of Psychiatry, King's College London, MRC SGDP Centre, SE5 8AF, UK; University of Alberta, Department of Psychiatry and Medical Genetics, Edmonton, Alberta, T6G 2E1, Canada.

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http://dx.doi.org/10.1016/j.psychres.2014.07.024DOI Listing
December 2014

The 12th Annual Pharmacogenetics in Psychiatry meeting report.

Psychiatr Genet 2014 Oct;24(5):218-20

aDivision of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks bThe Feinstein Institute for Medical Research, Manhasset cDepartment of Psychiatry,Hofstra North Shore-LIJ School of Medicine, Hempstead, New York, USA dDepartment of Psychiatry and Medical Genetics, University of Alberta, Edmonton, Canada eInstitute of Psychiatry, King's College London, London, UK.

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http://dx.doi.org/10.1097/YPG.0000000000000041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141887PMC
October 2014

Genomics for clinical utility: the future is near.

Genome Med 2014 28;6(1). Epub 2014 Jan 28.

Department of Psychiatry, University of Alberta, Edmonton, AB T6G 2E1, Canada ; Department of Medical Genetics, University of Alberta, Edmonton, AB T6G 2E1, Canada.

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http://dx.doi.org/10.1186/gm522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978760PMC
August 2014

Potential role of the combination of galantamine and memantine to improve cognition in schizophrenia.

Schizophr Res 2014 Aug 28;157(1-3):84-9. Epub 2014 May 28.

Sheppard Pratt Health System, Baltimore, MD, USA; Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.schres.2014.04.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099270PMC
August 2014

Association of tardive dyskinesia with variation in CYP2D6: Is there a role for active metabolites?

J Psychopharmacol 2014 Jul 4;28(7):665-70. Epub 2014 Mar 4.

MRC Social Genetic and Developmental Psychiatry Centre, King's College London, London, UK Department of Psychiatry and Medical Genetics, University of Alberta, Edmonton, AB, Canada.

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http://dx.doi.org/10.1177/0269881114523861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950711PMC
July 2014

Effects of antidepressant drug exposure on gene expression in the developing cerebral cortex.

Synapse 2014 May 13;68(5):209-20. Epub 2014 Feb 13.

MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London, United Kingdom; Department of Psychiatry and Neuroscience Program, Harvard Medical School and McLean Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1002/syn.21732DOI Listing
May 2014

Modulation of amygdala response and connectivity in depression by serotonin transporter polymorphism and diagnosis.

J Affect Disord 2013 Aug 2;150(1):96-103. Epub 2013 May 2.

Department of Old Age Psychiatry, Institute of Psychiatry, King's College London, UK.

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http://dx.doi.org/10.1016/j.jad.2013.02.028DOI Listing
August 2013

Serum and gene expression profile of cytokines in first-episode psychosis.

Brain Behav Immun 2013 Jul 28;31:90-5. Epub 2012 Jun 28.

King's College London, Institute of Psychiatry, Department of Psychological Medicine, London, UK.

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http://dx.doi.org/10.1016/j.bbi.2012.06.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675681PMC
July 2013

White matter abnormalities and illness severity in major depressive disorder.

Br J Psychiatry 2012 Jul 10;201(1):33-9. Epub 2012 May 10.

MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, De Crespigny Park, London, UK.

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http://dx.doi.org/10.1192/bjp.bp.111.100594DOI Listing
July 2012

Pharmacogenetic studies of change in cortisol on ecstasy (MDMA) consumption.

J Psychopharmacol 2012 Mar 3;26(3):419-28. Epub 2011 Oct 3.

King's College London, Institute of Psychiatry, Addiction Department, London, UK.

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http://dx.doi.org/10.1177/0269881111415737DOI Listing
March 2012

Ecstasy (MDMA)-induced hyponatraemia is associated with genetic variants in CYP2D6 and COMT.

J Psychopharmacol 2012 Mar 1;26(3):408-18. Epub 2012 Feb 1.

MRC Social Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London, UK.

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http://dx.doi.org/10.1177/0269881111434624DOI Listing
March 2012

Can genetics inform the management of cognitive deficits in schizophrenia?

J Psychopharmacol 2012 Mar 10;26(3):334-48. Epub 2012 Feb 10.

King's College London, Institute of Psychiatry, MRC SGDP Centre, London, UK.

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http://dx.doi.org/10.1177/0269881111434623DOI Listing
March 2012

Special issue on Pharmacogenetics.

J Psychopharmacol 2012 Mar;26(3):333

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http://dx.doi.org/10.1177/0269881112439150DOI Listing
March 2012

Antidepressants and the resilience to early-life stress in inbred mouse strains.

Pharmacogenet Genomics 2011 Dec;21(12):779-89

INSERM U862, Avenir group Physiopathology of Energy Balance and Obesity, Université de Bordeaux 2, Bordeaux, France.

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http://dx.doi.org/10.1097/FPC.0b013e32834b3f35DOI Listing
December 2011

Costs and outcomes associated with an aripiprazole add-on or switching open-label study in psychosis.

J Psychopharmacol 2011 May 22;25(5):675-84. Epub 2010 Feb 22.

MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry at King's College London, London, UK.

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http://dx.doi.org/10.1177/0269881109358198DOI Listing
May 2011

The Ninth Annual Pharmacogenetics in Psychiatry Meeting report.

Psychiatr Genet 2011 Apr;21(2):112-3

The Zucker Hillside Hospital, Glen Oaks, New York 11004, USA.

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http://dx.doi.org/10.1097/YPG.0b013e328341e07eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704917PMC
April 2011

Gender differences in antidepressant drug response.

Int Rev Psychiatry 2010 ;22(5):485-500

MRC SGDP Centre, Institute of Psychiatry, King's College London, 16 De Crespigny Park, Denmark Hill, London, UK.

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http://dx.doi.org/10.3109/09540261.2010.496448DOI Listing
March 2011

Pharmacogenetics of antidepressant response.

Expert Rev Neurother 2011 Jan;11(1):101-25

MRC SGDP Centre, Institute of Psychiatry at King's College London, 16 De Crespigny Park, Denmark Hill, London, SE5 8AF, UK.

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http://dx.doi.org/10.1586/ern.10.186DOI Listing
January 2011

Disclosure of religious beliefs.

Br J Psychiatry 2009 Oct;195(4):368; author reply 368-9

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http://dx.doi.org/10.1192/bjp.195.4.368bDOI Listing
October 2009

Disclosure of religious beliefs.

Br J Psychiatry 2009 Oct;195(4):368; author reply 368-9

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http://dx.doi.org/10.1192/bjp.195.4.368bDOI Listing
October 2009

Routine evaluation in first episode psychosis services: feasibility and results from the MiData project.

Soc Psychiatry Psychiatr Epidemiol 2008 Dec 13;43(12):960-7. Epub 2008 Jun 13.

Institute of Psychiatry, PO80 MRC SGDP Centre, De Crespigny Park, London, UK.

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http://link.springer.com/10.1007/s00127-008-0386-1
Publisher Site
http://dx.doi.org/10.1007/s00127-008-0386-1DOI Listing
December 2008

Change in sexual dysfunction with aripiprazole: a switching or add-on study.

J Psychopharmacol 2008 May;22(3):244-53

COAST Team (Croydon Early Intervention in Psychosis Service), Westways Resource Centre, Croydon, UK.

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http://dx.doi.org/10.1177/0269881107082901DOI Listing
May 2008

Vasopressin and oxytocin secretion in response to the consumption of ecstasy in a clubbing population.

J Psychopharmacol 2006 May;20(3):400-10

National Addiction Centre, Institute of Psychiatry, King's College London, 4 Windsor Walk, London SE5 8AF, UK.

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http://dx.doi.org/10.1177/0269881106061514DOI Listing
May 2006

The genetics of depression and related traits.

Curr Psychiatry Rep 2005 Apr;7(2):117-24

MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, UK.

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http://dx.doi.org/10.1007/s11920-005-0008-5DOI Listing
April 2005